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The New England Journal of Medicine, ISSN 0028-4793, 10/2019, Volume 381, Issue 17, pp. 1653 - 1662
Hereditary thrombotic thrombocytopenic purpura is an autosomal recessive disorder caused by the absence of a functional protease (ADAMTS13) that processes von... 
TTP | MEDICINE, GENERAL & INTERNAL | PLASMA | POLYMORPHISMS | FACTOR-VIII | PURIFICATION | ADAMTS13 DEFICIENCY | VON-WILLEBRAND-FACTOR | FACTOR-CLEAVING PROTEASE | UPSHAW-SCHULMAN SYNDROME | PREGNANCY
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 09/2019, Volume 104, Issue 10, pp. 2107 - 2115
Congenital thrombotic thrombocytopenic purpura is an autosomal recessive inherited disease with a clinically heterogeneous course and an incompletely... 
PATHOGENESIS | DIAGNOSIS | MANAGEMENT | PLASMA | UPSHAW-SCHULMAN-SYNDROME | ADAMTS13 MUTATIONS | PREVALENCE | HEMATOLOGY | ASSOCIATION | FACTOR-CLEAVING PROTEASE | PREGNANCY
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4930 - 4930
Acquired hemophilia A (AHA) is a rare autoimmune disease caused by circulating autoantibodies inhibiting coagulation factor VIII (FVIII), leading to a... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1093 - 1093
Background: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening autoimmune thrombotic microangiopathy caused by a deficiency in the... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5003 - 5003
Abstract INTRODUCTION: Low ADAMTS13 activity is associated with an increased risk of thrombotic thrombocytopenic purpura (TTP). This may be caused by the... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4908 - 4908
Background: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare but life-threatening thrombotic microangiopathy, with an untreated mortality rate of... 
Journal Article
American Journal of Hematology, ISSN 0361-8609, 10/2019, Volume 94, Issue 10, pp. E259 - E261
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2365 - 2365
Background: Acquired thrombotic thrombocytopenic purpura (aTTP) is an acute, life-threatening thrombotic microangiopathy that requires urgent and specialized... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2366 - 2366
Background: Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening autoimmune thrombotic microangiopathy that involves abnormal... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 2496 - 2496
Abstract Introduction. Prekallikrein (PK) and high-molecular-weight kininogen (HK) deficiencies are ultra-rare, autosomal-recessive defects of the contact... 
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 11/2019, Volume 20, Issue 23, p. 5963
Cellular factor XIII (cFXIII, FXIII-A2), a transglutaminase, has been demonstrated in a few cell types. Its main function is to cross-link proteins by... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 373 - 373
Abstract Introduction : Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy, in which accumulation of... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3739 - 3739
Abstract Introduction : During the clinical development of caplacizumab, safety and tolerability data have been accrued from Phase I, Phase II, and Phase III... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1142 - 1142
Abstract Introduction : Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening autoimmune blood clotting disorder, manifested by... 
Journal Article
HAMOSTASEOLOGIE, ISSN 0720-9355, 01/2017, Volume 37, Issue 1, pp. 9 - 11
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3744 - 3744
Abstract Introduction : Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy. A severe deficiency in... 
Journal Article
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