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1. Full Text Clinical history of the theranostic radionuclide approach to neuroendocrine tumors and other types of cancer: Historical review based on an interview of Eric P. Krenning by Rachel Levine
by Levine, R and Krenning, Eric
The Journal of nuclear medicine (1978), ISSN 0161-5505, 09/2017, Volume 58, Issue Suppl 2, pp. 3S - 9S
PRRT | PSMA | Somatostatin | Neuroendocrine | Peptide | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Neuroendocrine Tumors - radiotherapy | Radioisotopes - therapeutic use | History, 21st Century | History, 20th Century | Humans | Isotope Labeling | Interviews as Topic | Radiotherapy - history | Neuroendocrine Tumors - diagnosis | Diagnosis | Receptors, Peptide - metabolism | Index Medicus
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2. Full Text Gastroenteropancreatic neuroendocrine tumours
by Modlin, Irvin M, Prof and Oberg, Kjell, Prof and Chung, Daniel C, MD and Jensen, Robert T, MD and de Herder, Wouter W, MD and Thakker, Rajesh V, Prof and Caplin, Martyn, MD and Delle Fave, Gianfranco, Prof and Kaltsas, Greg A, MD and Krenning, Eric P, Prof and Moss, Steven F, MD and Nilsson, Ola, Prof and Rindi, Guido, MD and Salazar, Ramon, MD and Ruszniewski, Philippe, Prof and Sundin, Anders, MD
The lancet oncology, ISSN 1470-2045, 2008, Volume 9, Issue 1, pp. 61 - 72
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Carcinoma, Neuroendocrine - metabolism | Somatostatin - analogs & derivatives | Pancreatic Neoplasms - metabolism | Molecular Biology | Carcinoma, Neuroendocrine - classification | Humans | Gastrointestinal Neoplasms - therapy | Biomarkers, Tumor | Animals | Carcinoma, Neuroendocrine - pathology | Pancreatic Neoplasms - physiopathology | Somatostatin - therapeutic use | Gastrointestinal Neoplasms - physiopathology | Somatostatin - metabolism | Gastrointestinal Neoplasms - metabolism | Pancreatic Neoplasms - therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus | Medicin och hälsovetenskap
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3. Full Text To serve and protect: Enzyme inhibitors as radiopeptide escorts promote tumor targeting
by Nock, Berthold and Maina, Theodosia and Krenning, Eric and Jong, Marcel
The Journal of nuclear medicine (1978), ISSN 0161-5505, 01/2014, Volume 55, Issue 1, pp. 121 - 127
Enzyme inhibition | Radiopeptide tumor targeting | In vivo stability | Neutral endopeptidase | Phosphoramidon | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gastrins - chemistry | Neoplasm Transplantation | Radiopharmaceuticals - pharmacokinetics | Peptides - chemistry | Humans | Tomography, Emission-Computed, Single-Photon | Glycopeptides - chemistry | Male | Tomography, X-Ray Computed | Chromatography, High Pressure Liquid | Indium Radioisotopes - pharmacokinetics | Mice, SCID | Neoplasms - diagnostic imaging | Animals | Enzyme Inhibitors - chemistry | Protein Binding | Female | Mice | Somatostatin - chemistry | Bombesin - chemistry | Enzymes | Sensitivity analysis | Peptides | Metabolism | Rodents | Tumors | Index Medicus
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4. Full Text Theranostic perspectives in prostate cancer with the gastrin-releasing peptide receptor antagonist NeoBOMB1: Preclinical and first clinical results
by Nock, Berthold and Kaloudi, Katerina and Lymperis, Emmanouil and Giarika, A and Kulkarni, Harshad R and Klette, Ingo and Singh, A and Krenning, Eric and Jong, Marion and Maina, Theodosia and Baüm, Richard
The Journal of nuclear medicine (1978), ISSN 0161-5505, 01/2017, Volume 58, Issue 1, pp. 75 - 80
Radionuclide therapy | Gastrin releasing peptide receptor antagonist | Prostate cancer | Theranostic applications | Molecular Tumor Imaging | PET | SPECT | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - radiotherapy | Radioisotopes - pharmacokinetics | Radioisotopes - therapeutic use | Radiopharmaceuticals - pharmacokinetics | Humans | Male | Metabolic Clearance Rate | Treatment Outcome | Prostatic Neoplasms - diagnosis | Receptors, Bombesin - antagonists & inhibitors | Cell Survival - radiation effects | Tissue Distribution | Pilot Projects | Receptors, Bombesin - metabolism | Animals | Theranostic Nanomedicine - methods | Cell Line, Tumor | Mice | Bombesin - therapeutic use | Bombesin - pharmacokinetics | Radiopharmaceuticals - therapeutic use | Ligands | Membranes | Peptides | Rodents | Cells | Index Medicus
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5. Full Text Long-term tolerability of PRRT in 807 patients with neuroendocrine tumours: the value and limitations of clinical factors
by Bodei, Lisa and Bodei, Lisa and Kidd, Mark and Kidd, Mark and Paganelli, Giovanni and Paganelli, Giovanni and Grana, Chiara M and Grana, Chiara M and Drozdov, Ignat and Drozdov, Ignat and Cremonesi, Marta and Cremonesi, Marta and Lepensky, Christopher and Lepensky, Christopher and Kwekkeboom, Dik J and Kwekkeboom, Dik J and Baum, Richard P and Baum, Richard P and Krenning, Eric P and Krenning, Eric P and Modlin, Irvin M and Modlin, Irvin M
European journal of nuclear medicine and molecular imaging, ISSN 1619-7070, 1/2015, Volume 42, Issue 1, pp. 5 - 19
PRRT | Medicine & Public Health | Orthopedics | Oncology | Bone marrow toxicity | Nuclear Medicine | Imaging / Radiology | Cardiology | NET | Nephrotoxicity | Decision tree analysis | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Humans | Middle Aged | Male | Leukemia, Myeloid, Acute - etiology | Neuroendocrine Tumors - diagnosis | Lutetium - administration & dosage | Yttrium Radioisotopes - administration & dosage | Aged, 80 and over | Adult | Female | Lutetium - therapeutic use | Octreotide - administration & dosage | Child | Yttrium Radioisotopes - therapeutic use | Lutetium - adverse effects | Yttrium Radioisotopes - adverse effects | Octreotide - adverse effects | Radiation Dosage | Octreotide - therapeutic use | Myelodysplastic Syndromes - etiology | Radiopharmaceuticals - administration & dosage | Neuroendocrine Tumors - radiotherapy | Adolescent | Aged | Radiopharmaceuticals - adverse effects | Radiopharmaceuticals - therapeutic use | Receptors, Peptide - metabolism | Hypertension | Hemoglobin | Leukemia | Clinical trials | Neurology | Peptides | Neurons | Endocrine system | Tumors | Index Medicus
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6. Full Text Candidates for Peptide Receptor Radiotherapy Today and in the Future
by Reubi, Jean Claude and Macke, Helmut R and Krenning, Eric P
The Journal of nuclear medicine (1978), ISSN 0161-5505, 01/2005, Volume 46, Issue 1 suppl, pp. 67S - 75S
Tumor selection | Radiopeptides | Receptors | Tumor targeting | Peptide receptor radiation therapy | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Neoplasms - metabolism | Radioisotopes - pharmacokinetics | Drug Evaluation, Preclinical - trends | Humans | Peptides - pharmacokinetics | Cholecystokinin - pharmacokinetics | Cholecystokinin - therapeutic use | Biomarkers, Tumor - metabolism | Neoplasms - radiotherapy | Somatostatin - analogs & derivatives | Radioisotopes - therapeutic use | Radiopharmaceuticals - pharmacokinetics | Treatment Outcome | Clinical Trials as Topic | Substance P - therapeutic use | Somatostatin - pharmacokinetics | Practice Patterns, Physicians' - trends | Animals | Bombesin - therapeutic use | Somatostatin - therapeutic use | Bombesin - pharmacokinetics | Drug Delivery Systems - methods | Substance P - pharmacokinetics | Peptides - therapeutic use | Radiopharmaceuticals - therapeutic use | Practice Guidelines as Topic | Receptors, Peptide - metabolism | Index Medicus
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7. Full Text Treatment With the Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate: Toxicity, Efficacy, and Survival
by Dik J. Kwekkeboom and Wouter W. de Herder and Boen L. Kam and Casper H. van Eijck and Martijn van Essen and Peter P. Kooij and Richard A. Feelders and Maarten O. van Aken and Eric P. Krenning
Journal of clinical oncology, ISSN 0732-183X, 05/2008, Volume 26, Issue 13, pp. 2124 - 2130
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Tumors | Gastrointestinal Neoplasms - mortality | Humans | Middle Aged | Male | Gastrointestinal Neoplasms - pathology | Time Factors | Myelodysplastic Syndromes - chemically induced | Neuroendocrine Tumors - diagnostic imaging | Aged, 80 and over | Organometallic Compounds - therapeutic use | Adult | Female | Pancreatic Neoplasms - mortality | Neuroendocrine Tumors - pathology | Severity of Illness Index | Hematologic Diseases - chemically induced | Octreotide - analogs & derivatives | Risk Assessment | Organometallic Compounds - adverse effects | Pancreatic Neoplasms - pathology | Proportional Hazards Models | Carcinoid Tumor - diagnostic imaging | Octreotide - adverse effects | Logistic Models | Treatment Outcome | Octreotide - therapeutic use | Carcinoid Tumor - pathology | Disease-Free Survival | Gastrointestinal Neoplasms - diagnostic imaging | Neuroendocrine Tumors - mortality | Radionuclide Imaging | Aged | Chemical and Drug Induced Liver Injury | Radiopharmaceuticals - adverse effects | Carcinoid Tumor - mortality | Pancreatic Neoplasms - diagnostic imaging | Radiopharmaceuticals - therapeutic use | Index Medicus
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8. Full Text Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate in Patients With Endocrine Gastroenteropancreatic Tumors
by Dik J. Kwekkeboom and Jaap J. Teunissen and Willem H. Bakker and Peter P. Kooij and Wouter W. de Herder and Richard A. Feelders and Casper H. van Eijck and Jan-Paul Esser and Boen L. Kam and Eric P. Krenning
Journal of clinical oncology, ISSN 0732-183X, 04/2005, Volume 23, Issue 12, pp. 2754 - 2762
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Tumors | Octreotide - analogs & derivatives | Adenoma, Islet Cell - pathology | Organometallic Compounds - adverse effects | Carcinoid Tumor - drug therapy | Humans | Middle Aged | Pancreatic Neoplasms - pathology | Liver Neoplasms - drug therapy | Endocrine Gland Neoplasms - drug therapy | Organometallic Compounds - pharmacokinetics | Male | Treatment Outcome | Disease Progression | Carcinoid Tumor - pathology | Pancreatic Neoplasms - drug therapy | Adenoma, Islet Cell - drug therapy | Endocrine Gland Neoplasms - pathology | Aged, 80 and over | Organometallic Compounds - therapeutic use | Adult | Female | Receptors, Somatostatin | Aged | Liver Neoplasms - secondary | Index Medicus
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9. Full Text [99mTc]Tc-DB1 mimics with different-length PEG spacers: Preclinical comparison in GRPR-positive models
by Kanellopoulos, Panagiotis and Lymperis, Emmanouil and Kaloudi, Aikaterini and de Jong, Marion and Krenning, Eric P and Nock, Berthold A and Maina, Theodosia
Molecules (Basel, Switzerland), ISSN 1420-3049, 08/2020, Volume 25, Issue 15, p. 3418
Neprilysin-inhibition | PEG | Tc]Tc-DB1 mimic | Tumor targeting | Phosphoramidon | spacer | Gastrin-releasing peptide receptor targeting | Tc]Tc-radiotracer | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Cell culture | Animal models | Peptides | Xenotransplantation | Radioisotopes | Antagonists | Radioactive tracers | Blood | Mouse devices | Polyethylene glycol | Coinjection | Xenografts | Physiology | Dosimetry | Pancreas | Radioactivity | Cell membranes | Stability analysis | Liquid chromatography | Metabolism | High-performance liquid chromatography | Gastrin-releasing peptide | Quality control | Gastrin | Affinity | Neprilysin | Pharmacokinetics | Prostate | Binding sites | Tumors | Index Medicus | [99mTc]Tc-DB1 mimic | tumor targeting | PEGx-spacer | neprilysin-inhibition | gastrin-releasing peptide receptor targeting | [99mTc]Tc-radiotracer
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10. Full Text Long-term efficacy, survival, and safety of [177Lu-DOTA0,Tyr3]octreotate in patients with gastroenteropancreatic and bronchial neuroendocrine tumors
by Brabander, Tessa and Van Der Zwan, Wouter A and Teunissen, Jaap J.M and Kam, Boen L.R and Feelders, Richard A and De Herder, Wouter W and Van Eijck, Casper H.J and Franssen, Gaston J.H and Krenning, Eric P and Kwekkeboom, Dik J
Clinical cancer research, ISSN 1078-0432, 08/2017, Volume 23, Issue 16, pp. 4617 - 4624
Life Sciences & Biomedicine | Oncology | Science & Technology | Outcome Assessment (Health Care) - methods | Humans | Middle Aged | Male | Intestinal Neoplasms - radiotherapy | Leukemia - etiology | Time Factors | Aged, 80 and over | Organometallic Compounds - therapeutic use | Adult | Female | Stomach Neoplasms - radiotherapy | Acute Disease | Octreotide - analogs & derivatives | Organometallic Compounds - adverse effects | Kaplan-Meier Estimate | Octreotide - adverse effects | Pancreatic Neoplasms - radiotherapy | Treatment Outcome | Octreotide - therapeutic use | Myelodysplastic Syndromes - etiology | Neuroendocrine Tumors - radiotherapy | Bronchial Neoplasms - radiotherapy | Outcome Assessment (Health Care) - statistics & numerical data | Aged | Radiopharmaceuticals - adverse effects | Radiopharmaceuticals - therapeutic use | Therapy | Membranes | Effectiveness | Kidneys | Toxicity | Leukemia | Radioisotopes | Cell membranes | Survival | Patients | Lutetium | Myelodysplastic syndrome | Metastases | Confidence intervals | Receptors | Experimental design | Safety engineering | Renal failure | Somatostatin | Safety | Somatostatin receptors | Tumors | Cancer | Neuroendocrine tumors | Index Medicus
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11. Full Text Neuroendocrine tumours: The role of imaging for diagnosis and therapy
by Van Essen, Martijn and Sundin, Anders and Krenning, Eric P and Kwekkeboom, Dik J
Nature reviews. Endocrinology, ISSN 1759-5029, 02/2014, Volume 10, Issue 2, pp. 102 - 114
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Pancreatic Neoplasms - diagnosis | Humans | Tomography, Emission-Computed, Single-Photon | Tomography, X-Ray Computed | Treatment Outcome | Neuroendocrine Tumors - diagnosis | Positron-Emission Tomography | Diagnostic Imaging - methods | Pancreatic Neoplasms - drug therapy | Magnetic Resonance Imaging | Neuroendocrine Tumors - drug therapy | Intestinal Neoplasms - diagnosis | Radiopharmaceuticals | Intestinal Neoplasms - drug therapy | CT imaging | Health aspects | Usage | Index Medicus
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