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1. Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review
by Kovacic, Jason C and Dimmeler, Stefanie and Harvey, Richard P and Finkel, Toren and Aikawa, Elena and Krenning, Guido and Baker, Andrew H
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2019, Volume 73, Issue 2, pp. 190 - 209
cardiovascular | EndMT | endothelial to mesenchymal transition | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiovascular Diseases - etiology | Animals | Signal Transduction | Heart - embryology | Humans | Epithelial-Mesenchymal Transition | Hypertension | Cell culture | Phenotypes | Mesenchyme | Disease | Laboratories | Lung diseases | Muscles | Smooth muscle | Gene expression | Endothelial cells | Endothelium | Arteriosclerosis | Atherosclerosis | Genetic engineering | Cardiovascular diseases | Cancer
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2. Full Text The origin of fibroblasts and mechanism of cardiac fibrosis
by Krenning, Guido and Zeisberg, Elisabeth and Kalluri, Raghu
Journal of cellular physiology, ISSN 0021-9541, 11/2010, Volume 225, Issue 3, pp. 631 - 637
endothelial-mesenchymal transition | ENDOTHELIAL CELLS | fibroblast | CARDIAC FIBROSIS | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Myocardial Contraction | Coronary Vessels - pathology | Excitation Contraction Coupling | Heart Diseases - metabolism | Signal Transduction | Heart Diseases - physiopathology | Coronary Vessels - physiopathology | Humans | Extracellular Matrix - metabolism | Myocardium - pathology | Fibroblasts - pathology | Morphogenesis | Cell Lineage | Phenotype | Animals | Myocardium - metabolism | Fibrosis | Stem Cells - pathology | Cell Transdifferentiation | Endothelial Cells - pathology | Heart Diseases - pathology | Neovascularization, Physiologic | Fibroblasts - metabolism | Index Medicus
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3. Full Text Gastroenteropancreatic neuroendocrine tumours
by Modlin, Irvin M, Prof and Oberg, Kjell, Prof and Chung, Daniel C, MD and Jensen, Robert T, MD and de Herder, Wouter W, MD and Thakker, Rajesh V, Prof and Caplin, Martyn, MD and Delle Fave, Gianfranco, Prof and Kaltsas, Greg A, MD and Krenning, Eric P, Prof and Moss, Steven F, MD and Nilsson, Ola, Prof and Rindi, Guido, MD and Salazar, Ramon, MD and Ruszniewski, Philippe, Prof and Sundin, Anders, MD
The lancet oncology, ISSN 1470-2045, 2008, Volume 9, Issue 1, pp. 61 - 72
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Carcinoma, Neuroendocrine - metabolism | Somatostatin - analogs & derivatives | Pancreatic Neoplasms - metabolism | Molecular Biology | Carcinoma, Neuroendocrine - classification | Humans | Gastrointestinal Neoplasms - therapy | Biomarkers, Tumor | Animals | Carcinoma, Neuroendocrine - pathology | Pancreatic Neoplasms - physiopathology | Somatostatin - therapeutic use | Gastrointestinal Neoplasms - physiopathology | Somatostatin - metabolism | Gastrointestinal Neoplasms - metabolism | Pancreatic Neoplasms - therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Epigenetic Regulation of Endothelial-to-Mesenchymal Transition in Chronic Heart Disease: Histone Modifications, DNA Methylation, and Noncoding RNAs
by Hulshoff, Melanie S and Xu, Xingbo and Krenning, Guido and Zeisberg, Elisabeth M
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 09/2018, Volume 38, Issue 9, pp. 1986 - 1996
CIRCULATING MICRORNAS | heart failure | PROMOTER HYPERMETHYLATION | endothelial cells | RNA | PULMONARY-HYPERTENSION | FLUID SHEAR-STRESS | INDUCED CARDIAC FIBROSIS | epigenomics | DILATED CARDIOMYOPATHY | acetylation | FIBROBLAST ACTIVATION | GROWTH-FACTOR-BETA | HUMAN GENOME | DNA methylation | fibrosis | INFLAMMATORY CYTOKINES | untranslated | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology
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5. Full Text Endothelial-mesenchymal transition in atherosclerosis
by Souihol, Celine E M and Harmsen, Martin C and Evans, Paul C and Krenning, Guido
Cardiovascular research, ISSN 0008-6363, 03/2018, Volume 114, Issue 4, pp. 565 - 577
Regional blood flow | Remodelling | TGF-BETA | FLUID SHEAR-STRESS | Endothelial function | ENDOPLASMIC-RETICULUM STRESS | KINASE C-DELTA | CARDIAC-VALVE FORMATION | IDIOPATHIC PORTAL-HYPERTENSION | GROWTH-FACTOR-BETA | Transforming growth factor beta (TGF-beta) | SIGNALING PATHWAY | Atherosclerosis | Shear stress | Mechanotransduction | SMOOTH-MUSCLE-CELLS | NF-KAPPA-B | Endothelial-mesenchymal transition (EndMT) | Transforming growth factor beta (TGF-β) | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Atherosclerosis - pathology | Vascular Remodeling | Signal Transduction | Atherosclerosis - physiopathology | Endothelial Cells - metabolism | Humans | Extracellular Matrix - metabolism | Arteries - pathology | Plaque, Atherosclerotic | Atherosclerosis - metabolism | Arteries - metabolism | Cell Lineage | Phenotype | Animals | Arteries - physiopathology | Epithelial-Mesenchymal Transition | Inflammation Mediators - metabolism | Cell Plasticity | Hemodynamics | Endothelial Cells - pathology
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6. Full Text The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence
by Maleszewska, Monika and Vanchin, Byambasuren and Harmsen, Martin C and Krenning, Guido
Angiogenesis (London), ISSN 0969-6970, 01/2016, Volume 19, Issue 1, pp. 9 - 24
Endothelial cell | Chromatin | STEM-CELLS | ACTIVATION | DNA METHYLATION | CANCER CELLS | HUMAN CORONARY-ARTERIES | ZESTE HOMOLOG 2 | Fluid shear stress (FSS) | Enhancer of zeste homolog-2 (EZH2) | DISTURBED FLOW | EPIGENETIC THERAPY | IN-VITRO | GENOME-WIDE | Mechanotransduction | Biomedicine | Cancer Research | Oncology | Ophthalmology | Cardiology | Biomedicine general | Cell Biology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cell Cycle - genetics | Cell Adhesion - genetics | Cell Proliferation | Polycomb Repressive Complex 2 - genetics | Rheology | Humans | Gene Expression Regulation | Stress, Mechanical | Mitogen-Activated Protein Kinase 7 - metabolism | Gene Regulatory Networks | Down-Regulation - genetics | Enhancer of Zeste Homolog 2 Protein | Human Umbilical Vein Endothelial Cells - enzymology | Models, Biological | Human Umbilical Vein Endothelial Cells - cytology | Enzyme Activation | Polycomb Repressive Complex 2 - metabolism | Gene Ontology | Methyltransferases | Analysis | Influence | Research | Gene expression | Endothelium | Index Medicus | Original Paper
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