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PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90857
Antibodies that preferentially and specifically target pathological oligomeric protein and peptide assemblies, as opposed to their monomeric and amyloid... 
ALZHEIMERS-DISEASE | AMYLOID-BETA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | PREFIBRILLAR OLIGOMERS | SOLUTION NMR | MONOCLONAL-ANTIBODIES | A-BETA OLIGOMERS | PASSIVE-IMMUNIZATION | PARKINSONS-DISEASE | TAU OLIGOMERS | Parkinson Disease - pathology | alpha-Synuclein - immunology | Protein Multimerization - immunology | Antibody Affinity - immunology | Hippocampus - pathology | Proteins - immunology | Alzheimer Disease - pathology | alpha-Synuclein - chemistry | Epitopes - immunology | Hippocampus - metabolism | Animals | Alzheimer Disease - metabolism | Antibodies - immunology | Protein Binding | Amyloid beta-Peptides - immunology | Female | Epitopes - chemistry | Mice | Parkinson Disease - metabolism | Amyloid beta-Peptides - chemistry | Kinetics | Proteins - chemistry | alpha-Synuclein - metabolism | Antibodies, Monoclonal - immunology | Analysis | Immunoglobulin G | Monoclonal antibodies | Polymers | Health aspects | Alzheimer's disease | Methods | Antigenic determinants | Buried structures | Parkinson's disease | Peptides | Biochemistry | Synuclein | Monomers | Turnover rate | Design optimization | Design | Proteins | Oligomers | Protein folding | Immunotherapy | Rodents | Amyloid | Assemblies | Movement disorders | Binding | Immunization | Immunoglobulins | Polypeptides | Neurodegenerative diseases | Fibrils | Biophysics | Epitopes | Avidity | Diagnostic systems | Alzheimers disease | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153112
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 20, pp. 8245 - 8250
Journal Article
Internet Interventions, ISSN 2214-7829, 05/2016, Volume 4, Issue P1, pp. 82 - 91
Audiologists provide professional contact and support between appointments to clients with hearing impairment using telephone and e-mail, but more advanced and... 
Internet-based support system | Tele-health | Rehabilitation | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Health Sciences
Journal Article
FEBS Letters, ISSN 0014-5793, 04/2017, Volume 591, Issue 8, pp. 1167 - 1175
Low pH has a strong stabilising effect on the fibrillar assembly of amyloid β, which is associated with Alzheimer's disease. The stabilising effect is already... 
fibril | amyloid | abeta | surface plasmon resonance | histidine | stability | PROTEIN | DOCK-LOCK MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | PEPTIDE | OLIGOMERS | CELL BIOLOGY | BIOPHYSICS | FAMILIAL ALZHEIMERS-DISEASE | SURFACE-PLASMON RESONANCE | BINDING | AGGREGATION | BRAIN | Recombinant Proteins - metabolism | Surface Plasmon Resonance | Microscopy, Electron, Transmission | Peptide Fragments - metabolism | Humans | Recombinant Proteins - chemistry | Amyloid - chemistry | Amyloid - ultrastructure | Peptide Fragments - chemistry | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Amyloid beta-Peptides - genetics | Amyloid beta-Peptides - metabolism | Amyloid beta-Peptides - chemistry | Kinetics | Mutation | Protein Stability | Histidine - chemistry | Peptide Fragments - genetics | Protein Aggregation, Pathological - metabolism | Amino Acid Substitution | Hydrogen-Ion Concentration | Research Letters | Research Letter | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e98575
Mediator is an evolutionary conserved multi-protein complex present in all eukaryotes. It functions as a transcriptional coregulator by conveying signals from... 
RNA-POLYMERASE-II | ACTIVATION DOMAIN | SUBUNIT MED25 | LIGAND-BINDING | HUMAN MEDIATOR COMPLEX | MULTIDISCIPLINARY SCIENCES | NMR STRUCTURE | RESPONSIVE GENE-EXPRESSION | 9-AMINO-ACID TRANSACTIVATION DOMAIN | FLOWERING TIME | P53 | Transcription Factors - chemistry | Mediator Complex - metabolism | Herpes Simplex Virus Protein Vmw65 - chemistry | Humans | Models, Molecular | Nuclear Proteins - metabolism | Nuclear Proteins - chemistry | Arabidopsis - metabolism | Arabidopsis Proteins - metabolism | Transcription Factors - metabolism | Multiprotein Complexes - metabolism | Thermodynamics | Mediator Complex - chemistry | Arabidopsis Proteins - chemistry | Herpes Simplex Virus Protein Vmw65 - metabolism | Nuclear Magnetic Resonance, Biomolecular | Protein Binding | Protein Conformation | Protein Interaction Domains and Motifs | Kinetics | Arabidopsis - virology | Arabidopsis thaliana | Herpes simplex | Calorimetry | DNA binding proteins | Goods and services tax | Herpes simplex virus | Regulators | Transcription factors | Yeast | Nuclear magnetic resonance--NMR | Genomics | Viruses | Amino acids | Biochemistry | DNA-directed RNA polymerase | Proteins | Eukaryotes | Repressors | Evolutionary conservation | Stress response | Plant viruses | VP16 protein | Abiotic stress | Titration calorimetry | RNA polymerase | Biophysics | Gene expression | Ribonucleic acid--RNA | Polymerase | Acids | Plant stress | Herpes viruses | Affinity | Ligands | Titration | Surface plasmon resonance | Human behavior | Binding sites | RNA polymerase II | Biological Sciences | Med25 | Dreb2a | NMR | Naturvetenskap | Biokemi och molekylärbiologi | Biologiska vetenskaper | VP16 | Biochemistry and Molecular Biology | ITC | Mediator | conformational changes | Natural Sciences | RNA | Nuclear magnetic resonance | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e13928
Background: Alzheimers disease (AD) has been strongly linked to an anomalous self-assembly of the amyloid-beta peptide (A beta). The correlation between... 
TRAUMATIC BRAIN-INJURY | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | A-BETA | LONG-TERM POTENTIATION | PROTEIN-PRECURSOR | MONOCLONAL-ANTIBODIES | MEMORY LOSS | PEPTIDE | TRANSGENIC MICE | Surface Plasmon Resonance | Epitope Mapping | Amyloid beta-Peptides - pharmacology | Humans | Protein Multimerization | Antibody Affinity - immunology | Peptide Fragments - pharmacology | Immunoglobulin M - immunology | Amyloid - metabolism | Peptide Fragments - immunology | Female | Antibodies, Monoclonal - immunology | Cell Survival - drug effects | Enzyme-Linked Immunosorbent Assay | Antibodies, Monoclonal - pharmacology | Antibodies, Anti-Idiotypic - immunology | Cell Survival - immunology | Protein Binding - immunology | Autoantibodies - immunology | Peptide Fragments - chemistry | Animals | Amyloid - immunology | Cell Line, Tumor | Amyloid beta-Peptides - immunology | Mice | Mice, Inbred BALB C | Amyloid beta-Peptides - chemistry | Antibodies, Monoclonal - metabolism | Immunoglobulin M | Self assembly | Animal models | Peptides | Memory | Antibodies | Cytotoxicity | Biochemistry | Selectivity | Kinases | Monomers | Proteins | Oligomers | Immunology | Alzheimer's disease | Immunization | Immunological memory | Immunoglobulins | Autoantibodies | Neurodegenerative diseases | Pathological effects | Biophysics | Epitopes | Self-assembly | β-Amyloid | Avidity | Dimers | Kinetics | Alzheimers disease | Binding sites | Animal cognition | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Biokemi | Medical Biochemistry | MEDICINE | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology | Chemistry | MEDICIN | Kemi | medicinsk biokemi
Journal Article
American Journal of Audiology, ISSN 1059-0889, 09/2015, Volume 24, Issue 3, pp. 320 - 324
Journal Article
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 03/2017, Volume 21, Issue 3, pp. 376 - 389
The BabA adhesin mediates high-affinity binding of to the ABO blood group antigen-glycosylated gastric mucosa. Here we show that BabA is acid... 
gastric acidity | multimerization | diversity | Helicobacter pylori | gastric cancer | subpopulations | adaptation | polymorphism | acid responsiveness | blood group antigen-binding adhesion | CELLS | BLOOD-GROUP | VIROLOGY | EPITHELIUM | FORCE | DYNAMICS | MICROBIOLOGY | BINDING | ADHESIN | PROLINE | STOMACH | PARASITOLOGY | Bacterial Adhesion | Adhesins, Bacterial - metabolism | Gastric Mucosa - microbiology | Gastric Mucosa - pathology | Helicobacter pylori - physiology | Helicobacter Infections - pathology | Helicobacter Infections - microbiology | Hydrogen-Ion Concentration | Hydrogen-ion concentration | Health aspects | Gastrointestinal diseases | Life Sciences | Microbiology and Parasitology | Gastric Mucosa/microbiology | Helicobacter Infections/pathology | Helicobacter Infections/microbiology | Helicobacter pylori/physiology | Adhesins, Bacterial/metabolism | Bacteriology | Gastric Mucosa/pathology | Medical and Health Sciences | Medicin och hälsovetenskap | Molekylär cellbiologi | Klinisk medicin | Molecular Cellbiology | Cancerepidemiologi | Basic Medicine | Infektionsmedicin | Cell and Molecular Biology | Clinical Medicine | Infektionssjukdomar | Medicinska och farmaceutiska grundvetenskaper | Cancer Epidemiology | Infectious Medicine | Infectious Diseases | Cancer and Oncology | Cell- och molekylärbiologi | Cancer och onkologi
Journal Article