American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2010, Volume 203, Issue 1, pp. 68.e1 - 68.e6
Objective We sought to determine the association between tumor responses in vitro to platinum therapy by using the ChemoFx drug response marker and overall...
Obstetrics and Gynecology | platinum-based chemotherapy | chemotherapy drug response marker | ovarian cancer | in vitro chemosensitivity testing | DRUG | 1ST-LINE TREATMENT | CARBOPLATIN | ASSAY | PHASE-III | CHEMOTHERAPY | PACLITAXEL | OBSTETRICS & GYNECOLOGY | TRIAL | RESPONSES | CISPLATIN | Adenocarcinoma - pathology | Humans | Middle Aged | Ovarian Neoplasms - pathology | Proportional Hazards Models | Carboplatin - administration & dosage | Neoplasm Recurrence, Local - drug therapy | Survival Rate | Cisplatin - pharmacology | Adenocarcinoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cisplatin - administration & dosage | Young Adult | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Adult | Female | Aged | Carboplatin - pharmacology | Neoplasm Staging | Ovarian Neoplasms - drug therapy | Drug Screening Assays, Antitumor | Medical tests | Chemotherapy | Patient outcomes | Ovarian cancer | Cancer
Obstetrics and Gynecology | platinum-based chemotherapy | chemotherapy drug response marker | ovarian cancer | in vitro chemosensitivity testing | DRUG | 1ST-LINE TREATMENT | CARBOPLATIN | ASSAY | PHASE-III | CHEMOTHERAPY | PACLITAXEL | OBSTETRICS & GYNECOLOGY | TRIAL | RESPONSES | CISPLATIN | Adenocarcinoma - pathology | Humans | Middle Aged | Ovarian Neoplasms - pathology | Proportional Hazards Models | Carboplatin - administration & dosage | Neoplasm Recurrence, Local - drug therapy | Survival Rate | Cisplatin - pharmacology | Adenocarcinoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cisplatin - administration & dosage | Young Adult | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Adult | Female | Aged | Carboplatin - pharmacology | Neoplasm Staging | Ovarian Neoplasms - drug therapy | Drug Screening Assays, Antitumor | Medical tests | Chemotherapy | Patient outcomes | Ovarian cancer | Cancer
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2014, Volume 90, Issue 5, pp. 1083 - 1090
Purpose To utilize the National Cancer Data Base to evaluate trends in brachytherapy and alternative radiation therapy utilization in the treatment of cervical...
Radiology | Hematology, Oncology and Palliative Medicine | UNITED-STATES | UTERINE CERVIX | ONCOLOGY | CONCURRENT CHEMOTHERAPY | PATTERNS | RADIOTHERAPY PRACTICE | EXTERNAL-BEAM | BRACHYTHERAPY | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CARE | EPIDEMIOLOGY | Age Factors | United States | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Hispanic Americans - statistics & numerical data | Radiotherapy, Intensity-Modulated - utilization | Uterine Cervical Neoplasms - pathology | Carcinoma, Squamous Cell - radiotherapy | Radiosurgery - utilization | Socioeconomic Factors | Carcinoma, Squamous Cell - mortality | Brachytherapy - trends | Health Services Accessibility | Adult | Female | Retrospective Studies | Uterine Cervical Neoplasms - mortality | Radiotherapy, Intensity-Modulated - mortality | Brachytherapy - mortality | Radiotherapy Dosage | Continental Population Groups - classification | Uterine Cervical Neoplasms - radiotherapy | Cancer Care Facilities - supply & distribution | Databases, Factual - statistics & numerical data | Kaplan-Meier Estimate | Radiotherapy, Intensity-Modulated - trends | Radiosurgery - trends | Analysis of Variance | Survival Analysis | Aged | Brachytherapy - utilization | Radiosurgery - mortality | Continental Population Groups - statistics & numerical data | Databases | Radiotherapy | Analysis | Cervical cancer | MORTALITY | DIAGNOSIS | PATIENTS | NEOPLASMS | RADIOLOGY AND NUCLEAR MEDICINE | COMPARATIVE EVALUATIONS | HISTOLOGY | CHEMOTHERAPY | GYNECOLOGY | HAZARDS
Radiology | Hematology, Oncology and Palliative Medicine | UNITED-STATES | UTERINE CERVIX | ONCOLOGY | CONCURRENT CHEMOTHERAPY | PATTERNS | RADIOTHERAPY PRACTICE | EXTERNAL-BEAM | BRACHYTHERAPY | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CARE | EPIDEMIOLOGY | Age Factors | United States | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Hispanic Americans - statistics & numerical data | Radiotherapy, Intensity-Modulated - utilization | Uterine Cervical Neoplasms - pathology | Carcinoma, Squamous Cell - radiotherapy | Radiosurgery - utilization | Socioeconomic Factors | Carcinoma, Squamous Cell - mortality | Brachytherapy - trends | Health Services Accessibility | Adult | Female | Retrospective Studies | Uterine Cervical Neoplasms - mortality | Radiotherapy, Intensity-Modulated - mortality | Brachytherapy - mortality | Radiotherapy Dosage | Continental Population Groups - classification | Uterine Cervical Neoplasms - radiotherapy | Cancer Care Facilities - supply & distribution | Databases, Factual - statistics & numerical data | Kaplan-Meier Estimate | Radiotherapy, Intensity-Modulated - trends | Radiosurgery - trends | Analysis of Variance | Survival Analysis | Aged | Brachytherapy - utilization | Radiosurgery - mortality | Continental Population Groups - statistics & numerical data | Databases | Radiotherapy | Analysis | Cervical cancer | MORTALITY | DIAGNOSIS | PATIENTS | NEOPLASMS | RADIOLOGY AND NUCLEAR MEDICINE | COMPARATIVE EVALUATIONS | HISTOLOGY | CHEMOTHERAPY | GYNECOLOGY | HAZARDS
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2015, Volume 33, Issue 8, pp. 937 - 943
Purpose To examine the effects of disease burden, complex surgery, and residual disease (RD) status on progression-free (PFS) and overall survival (OS) in...
SURVIVAL | TRIAL | CYTOREDUCTIVE SURGERY | GYNECOLOGIC-ONCOLOGY-GROUP | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | VOLUME | RESIDUAL DISEASE | CARCINOMA | PREDICTION | Multivariate Analysis | Prognosis | Humans | Middle Aged | Peritoneal Neoplasms - surgery | Kaplan-Meier Estimate | Gynecologic Surgical Procedures | Treatment Outcome | Neoplasm, Residual | Disease-Free Survival | Time Factors | Ovarian Neoplasms - therapy | Adult | Female | Aged | Peritoneal Neoplasms - therapy | Ovarian Neoplasms - surgery | Gync17 | ORIGINAL REPORTS
SURVIVAL | TRIAL | CYTOREDUCTIVE SURGERY | GYNECOLOGIC-ONCOLOGY-GROUP | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | VOLUME | RESIDUAL DISEASE | CARCINOMA | PREDICTION | Multivariate Analysis | Prognosis | Humans | Middle Aged | Peritoneal Neoplasms - surgery | Kaplan-Meier Estimate | Gynecologic Surgical Procedures | Treatment Outcome | Neoplasm, Residual | Disease-Free Survival | Time Factors | Ovarian Neoplasms - therapy | Adult | Female | Aged | Peritoneal Neoplasms - therapy | Ovarian Neoplasms - surgery | Gync17 | ORIGINAL REPORTS
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e25056
Background: Epithelial ovarian cancer (EOC) is the deadliest gynecologic malignancy in the United States. Unfortunately, a validated protein...
OXIDATIVE STRESS | CARCINOGENESIS | PROTEIN | BIOLOGY | EXPRESSION | CARCINOMA | ABUNDANCE | RESOURCE | Humans | Middle Aged | Peroxiredoxins - metabolism | Neoplasms, Glandular and Epithelial - metabolism | Blotting, Western | Tandem Mass Spectrometry | Extracellular Fluid - metabolism | Carcinoma, Ovarian Epithelial | Chromatography, Liquid | Adult | Female | Aged | Ovarian Neoplasms - metabolism | Proteomics - methods | Proteins | Medical research | Biological products | Analysis | Medicine, Experimental | Liquid chromatography | Medical screening | Mass spectrometry | Enzyme-linked immunosorbent assay | Ovarian cancer | Peroxiredoxin | Oxidative stress | Ovarian carcinoma | Endometrial cancer | Oncology | Identification | Malignancy | Blood | Fluids | Surgery | Peripheral blood | Bioindicators | Peripheral circulation | Enzymes | Gel electrophoresis | Gynecology | Benign | Mass spectroscopy | Workflow | Breast cancer | Gene expression | Patients | Obstetrics | Esophagus | Medicine | Inflammatory bowel disease | Hospitals | Womens health | Medical prognosis | Proteomics | Biomarkers | Uterine cancer | Ascites | Prostate cancer | Immunoassays | Tumors | Cancer
OXIDATIVE STRESS | CARCINOGENESIS | PROTEIN | BIOLOGY | EXPRESSION | CARCINOMA | ABUNDANCE | RESOURCE | Humans | Middle Aged | Peroxiredoxins - metabolism | Neoplasms, Glandular and Epithelial - metabolism | Blotting, Western | Tandem Mass Spectrometry | Extracellular Fluid - metabolism | Carcinoma, Ovarian Epithelial | Chromatography, Liquid | Adult | Female | Aged | Ovarian Neoplasms - metabolism | Proteomics - methods | Proteins | Medical research | Biological products | Analysis | Medicine, Experimental | Liquid chromatography | Medical screening | Mass spectrometry | Enzyme-linked immunosorbent assay | Ovarian cancer | Peroxiredoxin | Oxidative stress | Ovarian carcinoma | Endometrial cancer | Oncology | Identification | Malignancy | Blood | Fluids | Surgery | Peripheral blood | Bioindicators | Peripheral circulation | Enzymes | Gel electrophoresis | Gynecology | Benign | Mass spectroscopy | Workflow | Breast cancer | Gene expression | Patients | Obstetrics | Esophagus | Medicine | Inflammatory bowel disease | Hospitals | Womens health | Medical prognosis | Proteomics | Biomarkers | Uterine cancer | Ascites | Prostate cancer | Immunoassays | Tumors | Cancer
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2011, Volume 123, Issue 3, pp. 616 - 616
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 01/2019, Volume 152, Issue 1, pp. 220 - 220
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2013, Volume 131, Issue 2, pp. 362 - 367
Abstract Objective Use of in vitro chemoresponse assays for informing effective treatment selection is a compelling clinical question and a topic of debate...
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Prospective clinical trial | Chemoresponse assay | Ovarian cancer | SURVIVAL | CHEMOSENSITIVITY | RESISTANCE ASSAY | BEVACIZUMAB | PERITONEAL | DRUG-RESISTANCE | CHEMOTHERAPY | OBSTETRICS & GYNECOLOGY | TRIAL | ONCOLOGY | PLATINUM RESISTANCE | EPITHELIAL OVARIAN | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Drug Resistance, Neoplasm | Survival Rate | Treatment Outcome | Disease-Free Survival | Peritoneal Neoplasms - drug therapy | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Female | Aged | Ovarian Neoplasms - drug therapy | Drug Screening Assays, Antitumor | Fallopian Tube Neoplasms - drug therapy | Medicine, Experimental | Medical research | Relapse | Diseases
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Prospective clinical trial | Chemoresponse assay | Ovarian cancer | SURVIVAL | CHEMOSENSITIVITY | RESISTANCE ASSAY | BEVACIZUMAB | PERITONEAL | DRUG-RESISTANCE | CHEMOTHERAPY | OBSTETRICS & GYNECOLOGY | TRIAL | ONCOLOGY | PLATINUM RESISTANCE | EPITHELIAL OVARIAN | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Drug Resistance, Neoplasm | Survival Rate | Treatment Outcome | Disease-Free Survival | Peritoneal Neoplasms - drug therapy | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Female | Aged | Ovarian Neoplasms - drug therapy | Drug Screening Assays, Antitumor | Fallopian Tube Neoplasms - drug therapy | Medicine, Experimental | Medical research | Relapse | Diseases
Journal Article
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2015, Volume 212, Issue 6, pp. 763.e1 - 763.e8
Objective Treatment for advanced-stage epithelial ovarian cancer (AEOC) includes primary debulking surgery (PDS) or neoadjuvant chemotherapy (NACT). A...
Obstetrics and Gynecology | neoadjuvant chemotherapy | primary debulking surgery | cost comparisons | ovarian cancer | CYTOREDUCTIVE SURGERY | GYNECOLOGIC-ONCOLOGY-GROUP | IMPROVED SURVIVAL | ELDERLY-WOMEN | PACLITAXEL | OBSTETRICS & GYNECOLOGY | TRIAL | CISPLATIN | QUALITY-OF-LIFE | INTRAPERITONEAL | CARCINOMA | Neoplasms, Glandular and Epithelial - pathology | Cytoreduction Surgical Procedures - economics | Humans | Neoplasms, Glandular and Epithelial - therapy | Ovarian Neoplasms - pathology | Neoadjuvant Therapy - economics | Neoplasms, Glandular and Epithelial - economics | Ovarian Neoplasms - economics | Cost-Benefit Analysis | Carcinoma, Ovarian Epithelial | Ovarian Neoplasms - therapy | Female | Aged | Chemotherapy, Adjuvant - economics | Neoplasm Staging | Cancer patients | Comparative analysis | Adjuvant treatment | Ovarian cancer | Cancer
Obstetrics and Gynecology | neoadjuvant chemotherapy | primary debulking surgery | cost comparisons | ovarian cancer | CYTOREDUCTIVE SURGERY | GYNECOLOGIC-ONCOLOGY-GROUP | IMPROVED SURVIVAL | ELDERLY-WOMEN | PACLITAXEL | OBSTETRICS & GYNECOLOGY | TRIAL | CISPLATIN | QUALITY-OF-LIFE | INTRAPERITONEAL | CARCINOMA | Neoplasms, Glandular and Epithelial - pathology | Cytoreduction Surgical Procedures - economics | Humans | Neoplasms, Glandular and Epithelial - therapy | Ovarian Neoplasms - pathology | Neoadjuvant Therapy - economics | Neoplasms, Glandular and Epithelial - economics | Ovarian Neoplasms - economics | Cost-Benefit Analysis | Carcinoma, Ovarian Epithelial | Ovarian Neoplasms - therapy | Female | Aged | Chemotherapy, Adjuvant - economics | Neoplasm Staging | Cancer patients | Comparative analysis | Adjuvant treatment | Ovarian cancer | Cancer
Journal Article
Journal of Gynecologic Surgery, ISSN 1042-4067, 02/2014, Volume 30, Issue 1, pp. 5 - 11
Objective: Cervical cancer occurs in ā¼1/2200 pregnancies. Limited data exist for optimal management of cervical adenocarcinomas, which have seen a...
Original Articles
Original Articles
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2012, Volume 125, Issue 3, pp. 677 - 682
Abstract Objective Our objective was to determine the rate of BRCA1/2 deficiency in platinum-sensitive and platinum-resistant tumors from a cohort of unselect...
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | BRCA mutations | Ovarian cancer | SURVIVAL | FREQUENT | PROTEIN | POLYMERASE | SOMATIC MUTATIONS | PACLITAXEL | OBSTETRICS & GYNECOLOGY | PHASE-III TRIAL | INHIBITION | CISPLATIN | ONCOLOGY | BRCANESS | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasms, Glandular and Epithelial - metabolism | Drug Resistance, Neoplasm | BRCA2 Protein - biosynthesis | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Genes, BRCA2 | Germ-Line Mutation | Adult | Female | Ovarian Neoplasms - metabolism | Genes, BRCA1 | BRCA1 Protein - deficiency | Ovarian Neoplasms - drug therapy | Neoplasms, Glandular and Epithelial - pathology | Gene Expression | BRCA1 Protein - biosynthesis | BRCA1 Protein - genetics | Disease-Free Survival | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Aged | BRCA2 Protein - deficiency | Neoplasm Staging | Organoplatinum Compounds - therapeutic use | BRCA2 Protein - genetics | Care and treatment | Chemotherapy | Genetic aspects | Cancer
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | BRCA mutations | Ovarian cancer | SURVIVAL | FREQUENT | PROTEIN | POLYMERASE | SOMATIC MUTATIONS | PACLITAXEL | OBSTETRICS & GYNECOLOGY | PHASE-III TRIAL | INHIBITION | CISPLATIN | ONCOLOGY | BRCANESS | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasms, Glandular and Epithelial - metabolism | Drug Resistance, Neoplasm | BRCA2 Protein - biosynthesis | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Genes, BRCA2 | Germ-Line Mutation | Adult | Female | Ovarian Neoplasms - metabolism | Genes, BRCA1 | BRCA1 Protein - deficiency | Ovarian Neoplasms - drug therapy | Neoplasms, Glandular and Epithelial - pathology | Gene Expression | BRCA1 Protein - biosynthesis | BRCA1 Protein - genetics | Disease-Free Survival | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Aged | BRCA2 Protein - deficiency | Neoplasm Staging | Organoplatinum Compounds - therapeutic use | BRCA2 Protein - genetics | Care and treatment | Chemotherapy | Genetic aspects | Cancer
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 10/2018, Volume 151, Issue 1, pp. 18 - 23
To determine the relationship between chemotherapy dose modification (dose adjustment or treatment delay), overall survival (OS) and progression-free survival...
Progression | Chemotherapy | Dose modification | G-CSF | Ovarian cancer | Dose reduction | SURVIVAL | CARBOPLATIN | CYCLOPHOSPHAMIDE | DOXORUBICIN | RANDOMIZED-TRIAL | PACLITAXEL | OBSTETRICS & GYNECOLOGY | PHASE-III TRIAL | BREAST-CANCER | CISPLATIN | ONCOLOGY | CARCINOMA | Doxorubicin - therapeutic use | Humans | Middle Aged | Ovarian Neoplasms - pathology | Ovarian Neoplasms - mortality | Dose-Response Relationship, Drug | Ovary - surgery | Carboplatin - therapeutic use | Neoplasms, Glandular and Epithelial - mortality | Female | Peritoneal Neoplasms - pathology | Neoplasms, Glandular and Epithelial - pathology | Ovary - pathology | Kaplan-Meier Estimate | Neoplasms, Glandular and Epithelial - therapy | Treatment Outcome | Cytoreduction Surgical Procedures - methods | Granulocyte Colony-Stimulating Factor - therapeutic use | Paclitaxel - therapeutic use | Peritoneal Neoplasms - mortality | Disease Progression | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Chemotherapy, Adjuvant - methods | Carcinoma, Ovarian Epithelial | Ovarian Neoplasms - therapy | Aged | Neoplasm Staging | Peritoneal Neoplasms - therapy | Women | Oncology, Experimental | Analysis | Patient outcomes | Adjuvant treatment | Research | Health aspects | Cancer | dose reduction | progression | dose modification | chemotherapy
Progression | Chemotherapy | Dose modification | G-CSF | Ovarian cancer | Dose reduction | SURVIVAL | CARBOPLATIN | CYCLOPHOSPHAMIDE | DOXORUBICIN | RANDOMIZED-TRIAL | PACLITAXEL | OBSTETRICS & GYNECOLOGY | PHASE-III TRIAL | BREAST-CANCER | CISPLATIN | ONCOLOGY | CARCINOMA | Doxorubicin - therapeutic use | Humans | Middle Aged | Ovarian Neoplasms - pathology | Ovarian Neoplasms - mortality | Dose-Response Relationship, Drug | Ovary - surgery | Carboplatin - therapeutic use | Neoplasms, Glandular and Epithelial - mortality | Female | Peritoneal Neoplasms - pathology | Neoplasms, Glandular and Epithelial - pathology | Ovary - pathology | Kaplan-Meier Estimate | Neoplasms, Glandular and Epithelial - therapy | Treatment Outcome | Cytoreduction Surgical Procedures - methods | Granulocyte Colony-Stimulating Factor - therapeutic use | Paclitaxel - therapeutic use | Peritoneal Neoplasms - mortality | Disease Progression | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Chemotherapy, Adjuvant - methods | Carcinoma, Ovarian Epithelial | Ovarian Neoplasms - therapy | Aged | Neoplasm Staging | Peritoneal Neoplasms - therapy | Women | Oncology, Experimental | Analysis | Patient outcomes | Adjuvant treatment | Research | Health aspects | Cancer | dose reduction | progression | dose modification | chemotherapy
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2011, Volume 124, Issue 3, pp. 575 - 581
Abstract Purpose Efflux transporters of the ATP-binding cassette (ABC) family are major determinants of chemoresistance in tumor cells. This study examined...
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | ABCB1 | ABCC2 | Common variants | GOG | Advanced stage ovarian cancer | MULTIDRUG TRANSPORTER | RESISTANCE PROTEIN | PACLITAXEL RESISTANCE | DRUG-RESISTANCE | P-GLYCOPROTEIN | OBSTETRICS & GYNECOLOGY | CELL LUNG-CANCER | ONCOLOGY | MDR1 GENE | EXPRESSION | MRP2 ABCC2 | SINGLE NUCLEOTIDE POLYMORPHISMS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Deoxycytidine - administration & dosage | Humans | Middle Aged | Carboplatin - administration & dosage | Cisplatin - administration & dosage | Polymorphism, Genetic | Ovarian Neoplasms - genetics | Young Adult | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Topotecan - administration & dosage | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | ATP Binding Cassette Transporter, Sub-Family B | Aged | Neoplasm Proteins - genetics | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Deoxycytidine - analogs & derivatives | Doxorubicin - administration & dosage | Women | Medical colleges | Chemotherapy | Patient outcomes | Genes | Oncology, Experimental | Genetic research | Genetic aspects | Research | Ovarian cancer | Cancer
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | ABCB1 | ABCC2 | Common variants | GOG | Advanced stage ovarian cancer | MULTIDRUG TRANSPORTER | RESISTANCE PROTEIN | PACLITAXEL RESISTANCE | DRUG-RESISTANCE | P-GLYCOPROTEIN | OBSTETRICS & GYNECOLOGY | CELL LUNG-CANCER | ONCOLOGY | MDR1 GENE | EXPRESSION | MRP2 ABCC2 | SINGLE NUCLEOTIDE POLYMORPHISMS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Deoxycytidine - administration & dosage | Humans | Middle Aged | Carboplatin - administration & dosage | Cisplatin - administration & dosage | Polymorphism, Genetic | Ovarian Neoplasms - genetics | Young Adult | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Topotecan - administration & dosage | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | ATP Binding Cassette Transporter, Sub-Family B | Aged | Neoplasm Proteins - genetics | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Deoxycytidine - analogs & derivatives | Doxorubicin - administration & dosage | Women | Medical colleges | Chemotherapy | Patient outcomes | Genes | Oncology, Experimental | Genetic research | Genetic aspects | Research | Ovarian cancer | Cancer
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2015, Volume 137, Issue 3, pp. 365 - 372
Abstract Background For node-positive vulvar cancer, adjuvant radiotherapy has an established benefit, whereas the impact of chemotherapy is unknown. A...
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Vulvar cancer | Chemotherapy | Adjuvant | Node positive | NCDB | GYNECOLOGIC-ONCOLOGY-GROUP | PROGNOSTIC-FACTORS | PHASE-II | CERVICAL-CANCER | OBSTETRICS & GYNECOLOGY | THERAPY | ONCOLOGY | PROPENSITY SCORE METHODS | CONCURRENT CHEMOTHERAPY | CISPLATIN CHEMOTHERAPY | SQUAMOUS-CELL CARCINOMA | CHEMORADIATION | Vulvar Neoplasms - surgery | Vulvar Neoplasms - radiotherapy | United States | Vulvar Neoplasms - drug therapy | Humans | Middle Aged | Lymphatic Metastasis | Chemoradiotherapy, Adjuvant | Young Adult | Vulvar Neoplasms - pathology | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Cohort Studies | Practice Guidelines as Topic | Databases | Analysis | Radiation | Adjuvant treatment | Cancer | Rankings | Health aspects
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Vulvar cancer | Chemotherapy | Adjuvant | Node positive | NCDB | GYNECOLOGIC-ONCOLOGY-GROUP | PROGNOSTIC-FACTORS | PHASE-II | CERVICAL-CANCER | OBSTETRICS & GYNECOLOGY | THERAPY | ONCOLOGY | PROPENSITY SCORE METHODS | CONCURRENT CHEMOTHERAPY | CISPLATIN CHEMOTHERAPY | SQUAMOUS-CELL CARCINOMA | CHEMORADIATION | Vulvar Neoplasms - surgery | Vulvar Neoplasms - radiotherapy | United States | Vulvar Neoplasms - drug therapy | Humans | Middle Aged | Lymphatic Metastasis | Chemoradiotherapy, Adjuvant | Young Adult | Vulvar Neoplasms - pathology | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Cohort Studies | Practice Guidelines as Topic | Databases | Analysis | Radiation | Adjuvant treatment | Cancer | Rankings | Health aspects
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 85, Issue 5, pp. 1269 - 1274
Purpose To examine clinical outcomes and relapse patterns in locally advanced vulvar carcinoma treated using preoperative chemotherapy and intensity modulated...
Radiology | Hematology, Oncology and Palliative Medicine | TRIAL | CISPLATIN | ONCOLOGY | CHEMORADIATION | PHASE-II | RADIOTHERAPY | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Lymph Node Excision | Chemoradiotherapy - adverse effects | Inguinal Canal | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Surgical Wound Infection - surgery | Cisplatin - administration & dosage | Neoplasm Recurrence, Local - pathology | Neoplasm, Residual | Vulvar Neoplasms - pathology | Vulvar Neoplasms - therapy | Fluorouracil - administration & dosage | Aged, 80 and over | Adult | Female | Radiotherapy Dosage | Vulvar Neoplasms - surgery | Chemoradiotherapy - methods | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Preoperative Care | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Radiotherapy, Intensity-Modulated | Chemotherapy | Relapse | Carcinoma | Nuclear radiation | Analysis | Radiotherapy | Cancer | Diseases | Index Medicus | SURGERY | PATIENTS | URACILS | LYMPH NODES | WOUNDS | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | RADIATION DOSES | TOXICITY | CHEMOTHERAPY
Radiology | Hematology, Oncology and Palliative Medicine | TRIAL | CISPLATIN | ONCOLOGY | CHEMORADIATION | PHASE-II | RADIOTHERAPY | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Lymph Node Excision | Chemoradiotherapy - adverse effects | Inguinal Canal | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Surgical Wound Infection - surgery | Cisplatin - administration & dosage | Neoplasm Recurrence, Local - pathology | Neoplasm, Residual | Vulvar Neoplasms - pathology | Vulvar Neoplasms - therapy | Fluorouracil - administration & dosage | Aged, 80 and over | Adult | Female | Radiotherapy Dosage | Vulvar Neoplasms - surgery | Chemoradiotherapy - methods | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Preoperative Care | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Radiotherapy, Intensity-Modulated | Chemotherapy | Relapse | Carcinoma | Nuclear radiation | Analysis | Radiotherapy | Cancer | Diseases | Index Medicus | SURGERY | PATIENTS | URACILS | LYMPH NODES | WOUNDS | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | RADIATION DOSES | TOXICITY | CHEMOTHERAPY
Journal Article
Cancer, ISSN 0008-543X, 03/2017, Volume 123, Issue 6, pp. 985 - 993
BACKGROUND The purpose of this study was to determine the effect of retroperitoneal (RP) exploration on progressionāfree survival (PFS) and overall survival...
surgical debulking | retroperitoneal exploration | disease burden | ovarian cancer | lymphadenectomy | SURVIVAL | METASTASIS | GOG 182 | PRIMARY CYTOREDUCTIVE SURGERY | NODE INVOLVEMENT | IMPACT | ONCOLOGY | DISEASE | CARCINOMA | Neoplasms, Glandular and Epithelial - pathology | Lymph Nodes - pathology | Humans | Middle Aged | Retroperitoneal Space - surgery | Ovarian Neoplasms - pathology | Treatment Outcome | Ovarian Neoplasms - mortality | Cytoreduction Surgical Procedures | Neoplasms, Glandular and Epithelial - surgery | Neoplasm Metastasis | Neoplasm Grading | Neoplasms, Glandular and Epithelial - mortality | Survival Analysis | Aged, 80 and over | Carcinoma, Ovarian Epithelial | Adult | Female | Aged | Neoplasm Staging | Odds Ratio | Ovarian Neoplasms - surgery | Cancer survivors | Care and treatment | Breast cancer | Social aspects | Lymphatic system | Ovarian carcinoma | Exploration | Oncology | Patients | Survival | Optimization | Lymph nodes | Ovarian cancer | Surgery | Aorta | Hazard assessment | Cancer | Lymph
surgical debulking | retroperitoneal exploration | disease burden | ovarian cancer | lymphadenectomy | SURVIVAL | METASTASIS | GOG 182 | PRIMARY CYTOREDUCTIVE SURGERY | NODE INVOLVEMENT | IMPACT | ONCOLOGY | DISEASE | CARCINOMA | Neoplasms, Glandular and Epithelial - pathology | Lymph Nodes - pathology | Humans | Middle Aged | Retroperitoneal Space - surgery | Ovarian Neoplasms - pathology | Treatment Outcome | Ovarian Neoplasms - mortality | Cytoreduction Surgical Procedures | Neoplasms, Glandular and Epithelial - surgery | Neoplasm Metastasis | Neoplasm Grading | Neoplasms, Glandular and Epithelial - mortality | Survival Analysis | Aged, 80 and over | Carcinoma, Ovarian Epithelial | Adult | Female | Aged | Neoplasm Staging | Odds Ratio | Ovarian Neoplasms - surgery | Cancer survivors | Care and treatment | Breast cancer | Social aspects | Lymphatic system | Ovarian carcinoma | Exploration | Oncology | Patients | Survival | Optimization | Lymph nodes | Ovarian cancer | Surgery | Aorta | Hazard assessment | Cancer | Lymph
Journal Article