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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5004 - 19
The mammalian inactive X-chromosome (Xi) is structurally distinct from all other chromosomes and serves as a model for how the 3D genome is organized. The Xi... 
ORGANIZATION | RNA | MULTIDISCIPLINARY SCIENCES | COHESIN | ARCHITECTURE | CTCF | CONFORMATION | CHROMATIN INTERACTIONS | DOMAINS | GENOME | PRINCIPLES | Domains | Gene silencing | Deactivation | Escape structures | Genomes | Methylation | Inactivation | Gene expression | Localization | Chromosomes | Three dimensional models
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2019, Volume 74, Issue 1, pp. 101 - 117.e10
During X-inactivation, Xist RNA spreads along an entire chromosome to establish silencing. However, the mechanism and functional RNA elements involved in... 
X-inactivation | lncRNA | HNRNPK | PRC2 | Hi-C | PRC1 | Polycomb | 3D genome | Xist | epigenetics | VISUALIZATION | RECRUITMENT | RESOLUTION REVEALS | REPEAT | GENE | DOSAGE COMPENSATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHROMOSOME INACTIVATION | HNRNP-K | GENOME | CELL BIOLOGY | Epigenetic inheritance | RNA | Molecular biology | Analysis | Genes
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 186 - 191
Journal Article
Quantitative Biology, ISSN 2095-4689, 06/2014, Volume 2, Issue 2, pp. 59 - 70
The CRISPR-Cas9 system, naturally a defense mechanism in prokaryotes, has been repurposed as an RNA-guided DNA targeting platform. It has been widely used for... 
target specificity | CRISPR | off-targets | Cas9 | genome engineering
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2018, Volume 69, Issue 4, pp. 648 - 663.e7
Journal Article
BIOLOGICAL PROCEDURES ONLINE, ISSN 1480-9222, 2017, Volume 19, Issue 1
Journal Article