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1. Full Text In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
by Meissner, Alexander and Brambrink, Tobias and Hochedlinger, Konrad and Foreman, Ruth and Ku, Manching and Jaenisch, Rudolf and Bernstein, Bradley E and Wernig, Marius
Nature (London), ISSN 0028-0836, 07/2007, Volume 448, Issue 7151, pp. 318 - 324
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Embryology: invertebrates and vertebrates. Teratology | Molecular embryology | Chromatin - metabolism | Homeodomain Proteins - metabolism | Male | Chimera - growth & development | Chimera - genetics | Teratoma - metabolism | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | DNA Methylation | Chimera - embryology | Female | Cell Differentiation | Fibroblasts - metabolism | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Gene Silencing | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Pluripotent Stem Cells - metabolism | Cell Lineage | Teratoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Fibroblasts - cytology | Mice | Chimera - metabolism | Chromatin - genetics | Stem cell research | Evaluation | Nucleotide sequence | Fibroblasts | Research | DNA binding proteins | Gene expression | Embryos | Deoxyribonucleic acid | DNA | Rodents | Stem cells | Ethics | Cloning | Derivation | Genomes | In vitro testing | Methylation | Index Medicus
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2. Full Text Mapping and analysis of chromatin state dynamics in nine human cell types
by Ernst, Jason and Kheradpour, Pouya and Mikkelsen, Tarjei S and Shoresh, Noam and Ward, Lucas D and Epstein, Charles B and Zhang, Xiaolan and Wang, Li and Issner, Robbyn and Coyne, Michael and Ku, Manching and Durham, Timothy and Kellis, Manolis and Bernstein, Bradley E
Nature (London), ISSN 0028-0836, 05/2011, Volume 473, Issue 7345, pp. 43 - 49
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Chromatin. Chromosome | Molecular and cellular biology | Molecular genetics | Cell Line | Chromatin - metabolism | Reproducibility of Results | Humans | Cell Physiological Phenomena | Cells, Cultured | Gene Expression Regulation | Chromosome Mapping | Transcription Factors - genetics | Promoter Regions, Genetic - genetics | Genome, Human - genetics | Hep G2 Cells | Cell Line, Tumor | Binding Sites | Chromatin - genetics | Mechanical properties | Chromosome mapping | Chromatin | Models | Proteins | Disease | Cellular biology | Stem cells | Genomes | RNA polymerase | Gene expression | Binding sites | Index Medicus
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3. Full Text Jarid2 and PRC2, partners in regulating gene expression
by Li, Gang and Margueron, Raphael and Ku, Manching and Chambon, Pierre and Bernstein, Bradley E and Reinberg, Danny
Genes & development, ISSN 0890-9369, 02/2010, Volume 24, Issue 4, pp. 368 - 380
Polycomb | Chromatin | Histone methylation | Jarid2 | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Polycomb-Group Proteins | Drosophila Proteins - metabolism | Nerve Tissue Proteins - genetics | Enhancer of Zeste Homolog 2 Protein | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Polycomb Repressive Complex 2 | Animals | Histone-Lysine N-Methyltransferase - metabolism | Gene Expression Regulation, Developmental | Protein Binding | Cell Differentiation | Mice | Repressor Proteins - metabolism | Analysis | Histones | Genetic aspects | Chemical properties | Gene expression | Structure | Mammals | Index Medicus | Research Paper | chromatin
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4. Full Text Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling
by Koche, Richard P and Smith, Zachary D and Adli, Mazhar and Gu, Hongcang and Ku, Manching and Gnirke, Andreas and Bernstein, Bradley E and Meissner, Alexander
Cell stem cell, ISSN 1934-5909, 2011, Volume 8, Issue 1, pp. 96 - 105
Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Chromatin - metabolism | Epigenesis, Genetic | Transcriptional Activation | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Histones - genetics | Mice | Histones - metabolism | Induced Pluripotent Stem Cells - cytology | Methylation | Cellular Reprogramming - physiology | Chromatin Assembly and Disassembly - physiology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Index Medicus
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5. Full Text Dissecting direct reprogramming through integrative genomic analysis
by Mikkelsen, Tarjei S and Schorderet, Patrick and Hanna, Jacob and Lander, Eric S and Ku, Manching and Bernstein, Bradley E and Jaenisch, Rudolf and Wernig, Marius and Zhang, Xiaolan and Meissner, Alexander
Nature (London), ISSN 0028-0836, 07/2008, Volume 454, Issue 7200, pp. 49 - 55
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Cell Line | Chromatin - metabolism | Embryonic Stem Cells - metabolism | Pluripotent Stem Cells - cytology | DNA (Cytosine-5-)-Methyltransferase 1 | Genomics | Transcription Factors - deficiency | Enzyme Inhibitors - pharmacology | Genome - genetics | Gene Expression Profiling | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Transcription Factors - genetics | DNA (Cytosine-5-)-Methyltransferases - metabolism | Pluripotent Stem Cells - metabolism | Azacitidine - pharmacology | Cell Lineage | DNA (Cytosine-5-)-Methyltransferases - genetics | DNA Methylation | Animals | Gene Expression Regulation, Developmental | Mice | Cellular Reprogramming - genetics | Proteins | Protease inhibitors | Cyclin-dependent kinases | Analysis | Stem cells | Dissection | Index Medicus
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6. Full Text Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
by Mikkelsen, Tarjei S and Ku, Manching and Jaffe, David B and Issac, Biju and Lieberman, Erez and Giannoukos, Georgia and Alvarez, Pablo and Brockman, William and Kim, Tae-Kyung and Koche, Richard P and Lee, William and Mendenhall, Eric and O'Donovan, Aisling and Presser, Aviva and Russ, Carsten and Xie, Xiaohui and Meissner, Alexander and Wernig, Marius and Jaenisch, Rudolf and Nusbaum, Chad and Lander, Eric S and Bernstein, Bradley E
Nature, ISSN 0028-0836, 08/2007, Volume 448, Issue 7153, pp. 553 - 560
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Chromatin. Chromosome | Molecular and cellular biology | Molecular genetics | Chromatin - metabolism | Genomic Imprinting | Pluripotent Stem Cells - cytology | Genome - genetics | Male | Promoter Regions, Genetic - genetics | Pluripotent Stem Cells - metabolism | Animals | Gene Expression Regulation, Developmental | Alleles | CpG Islands - genetics | Fibroblasts | Mice | Histones - metabolism | Transcription, Genetic - genetics | Methylation | Chromatin - genetics | Cell Lineage - genetics | Chromatin | Genomics | Research methodology | Rodents | Stem cells | Index Medicus
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7. Full Text An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
by Knoechel, Birgit and Roderick, Justine E and Williamson, Kaylyn E and Zhu, Jiang and Lohr, Jens G and Cotton, Matthew J and Gillespie, Shawn M and Fernandez, Daniel and Ku, Manching and Wang, Hongfang and Piccioni, Federica and Silver, Serena J and Jain, Mohit and Pearson, Daniel and Kluk, Michael J and Ott, Christopher J and Shultz, Leonard D and Brehm, Michael A and Greiner, Dale L and Gutierrez, Alejandro and Stegmaier, Kimberly and Kung, Andrew L and Root, David E and Bradner, James E and Aster, Jon C and Kelliher, Michelle A and Bernstein, Bradley E
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 4, pp. 364 - 370
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Chromatin - metabolism | Humans | Flow Cytometry | Chromatin Immunoprecipitation | Gene Expression Regulation, Neoplastic - drug effects | Indoles | Nuclear Proteins - genetics | Real-Time Polymerase Chain Reaction | Gene Expression Regulation, Neoplastic - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Enzyme-Linked Immunosorbent Assay | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Signal Transduction - genetics | Transcription Factors - genetics | Enzyme Inhibitors - therapeutic use | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Epigenesis, Genetic - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Histones - metabolism | Receptor, Notch1 - antagonists & inhibitors | Receptor, Notch1 - genetics | Chromatin - genetics | Care and treatment | Pharmacology, Experimental | Acute lymphocytic leukemia | Research | Drug resistance | Proteins | Genotype & phenotype | Leukemia | Epigenetics | Genomes | Kinases | Gene expression | Cancer therapies | Index Medicus
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8. Full Text Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons
by Schafer, Simon T and Paquola, Apua C. M and Stern, Shani and Gosselin, David and Ku, Manching and Pena, Monique and Kuret, Thomas J. M and Liyanage, Marvin and Mansour, Abed AlFatah and Jaeger, Baptiste N and Marchetto, Maria C and Glass, Christopher K and Mertens, Jerome and Gage, Fred H
Nature neuroscience, ISSN 1097-6256, 02/2019, Volume 22, Issue 2, pp. 243 - 255
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Induced Pluripotent Stem Cells - pathology | Autism Spectrum Disorder - genetics | Neurons - pathology | Humans | Neurons - physiology | Inhibitory Postsynaptic Potentials - physiology | Autism Spectrum Disorder - pathology | Gene Regulatory Networks | Nerve Net - physiopathology | Neural Stem Cells - pathology | Autism Spectrum Disorder - physiopathology | Care and treatment | Research | Gene expression | Neurons | Risk factors | Pervasive developmental disorders | Autism | Phenotypes | Chromatin | Developmental stages | Cortex | Stem cells | Neural stem cells | Priming | Pluripotency | Direct conversion | Inhibitory postsynaptic potentials | Index Medicus
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