Advanced Synthesis & Catalysis, ISSN 1615-4150, 05/2014, Volume 356, Issue 7, pp. 1549 - 1554
The palladium‐catalyzed acyloxylation of 2‐substituted 1,2,3‐triazoles with acids via direct sp2 CH bond activation is described. This reaction is applied to...
CH activation | palladium | acyloxylation | 2‐substituted 1,2,3‐triazoles | 2-substituted 1,2,3-triazoles | C-H activation
CH activation | palladium | acyloxylation | 2‐substituted 1,2,3‐triazoles | 2-substituted 1,2,3-triazoles | C-H activation
Journal Article
Organic Letters, ISSN 1523-7060, 03/2010, Volume 12, Issue 5, pp. 1052 - 1055
Direct cyanation of indole derivatives has been achieved with nontoxic K4[Fe(CN)6] as cyanating agent through Pd-catalyzed C−H bond activation.
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 05/2014, Volume 356, Issue 7, pp. 1549 - 1554
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 05/2014, Volume 356, Issue 7, pp. 1549 - 1554
The palladium-catalyzed acyloxylation of 2-substituted 1,2,3-triazoles with acids via direct sp super(2) C--H bond activation is described. This reaction is...
Synthesis | Activation | Tolerances | Derivatives | Catalysis | Bonding | Functional groups
Synthesis | Activation | Tolerances | Derivatives | Catalysis | Bonding | Functional groups
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 04/2014, Volume 2014, Issue 12, pp. 2576 - 2583
A highly efficient protocol for regioselective synthesis of diaryl ketones by palladium‐catalyzed direct acylation of arenes using thioethers as directing...
Regioselectivity | Homogeneous catalysis | C–H bond activation | Arenes | Synthetic methods | Palladium | Acylation | C-H bond activation | CHELATION-ASSISTED HYDROACYLATION | ROOM-TEMPERATURE | CHEMISTRY, ORGANIC | TERT-BUTYL HYDROPEROXIDE | OXIDATIVE ORTHO-ACYLATION | COUPLING REACTIONS | ALPHA-OXOCARBOXYLIC ACIDS | DECARBOXYLATIVE ORTHO-ACYLATION | BOND ACTIVATION | O-METHYL OXIMES | DIRECT CARBONYLATION | Sulfur compounds | Catalysis | Ketones
Regioselectivity | Homogeneous catalysis | C–H bond activation | Arenes | Synthetic methods | Palladium | Acylation | C-H bond activation | CHELATION-ASSISTED HYDROACYLATION | ROOM-TEMPERATURE | CHEMISTRY, ORGANIC | TERT-BUTYL HYDROPEROXIDE | OXIDATIVE ORTHO-ACYLATION | COUPLING REACTIONS | ALPHA-OXOCARBOXYLIC ACIDS | DECARBOXYLATIVE ORTHO-ACYLATION | BOND ACTIVATION | O-METHYL OXIMES | DIRECT CARBONYLATION | Sulfur compounds | Catalysis | Ketones
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 07/2014, Volume 79, Issue 13, pp. 6105 - 6112
Palladium-catalyzed alkoxylation of 2-aryl-1,2,3-triazoles was described in the presence of various groups in the aromatic rings. In addition, some other...
H BOND ACTIVATION | FUNCTIONALIZATION | C(SP)-H BONDS | CROSS-COUPLING REACTIONS | CARBON | ARYLATION | CHEMISTRY, ORGANIC | UNACTIVATED C(SP)-H | ANILIDES | C-H | Heterocyclic Compounds - chemistry | Nitrogen - chemistry | Triazoles - chemistry | Triazoles - chemical synthesis | Molecular Structure | Catalysis | Palladium - chemistry | Palladium | Chemical properties | Research | Triazoles | Alkylation
H BOND ACTIVATION | FUNCTIONALIZATION | C(SP)-H BONDS | CROSS-COUPLING REACTIONS | CARBON | ARYLATION | CHEMISTRY, ORGANIC | UNACTIVATED C(SP)-H | ANILIDES | C-H | Heterocyclic Compounds - chemistry | Nitrogen - chemistry | Triazoles - chemistry | Triazoles - chemical synthesis | Molecular Structure | Catalysis | Palladium - chemistry | Palladium | Chemical properties | Research | Triazoles | Alkylation
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 11/2019, p. 151390
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 12/2014, Volume 2014, Issue 35, pp. 7810 - 7813
A new efficient method for the direct alkenylation of 3‐arylsydnones by palladium‐catalyzed C–H functionalization was developed. The reaction proceeded...
C–H activation | Synthetic methods | Palladium | Nitrogen heterocycles | Alkenylation | C-H activation | ACTIVATION | ANALOGS | ARENES | ARYLATION | SYDNONES | CHEMISTRY, ORGANIC | OLEFINS
C–H activation | Synthetic methods | Palladium | Nitrogen heterocycles | Alkenylation | C-H activation | ACTIVATION | ANALOGS | ARENES | ARYLATION | SYDNONES | CHEMISTRY, ORGANIC | OLEFINS
Journal Article
Synlett, ISSN 0936-5214, 03/2015, Volume 26, Issue 5, pp. 681 - 687
Abstract A novel metal-free arylalkylation of N -aryl acrylamides with readily available azobisalkylnitriles leading to cyano-containing oxindoles has been...
letter | AIBN | oxindole | acrylamide | metal-free | aryalkylation
letter | AIBN | oxindole | acrylamide | metal-free | aryalkylation
Journal Article
ISSN 1477-0520, 6/2015, Volume 13, Issue 26, pp. 7146 - 7148
A mild and efficient method for the direct alkenylation of 2-benzyl-1,2,3-triazoles via Pd-catalyzed C-H bond activation was developed. This protocol was...
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 2013, Volume 13, Issue 5, pp. 713 - 719
1-Monosubstituted 1,2,3-triazoles have widespread applications in diverse fields, and their preparation has attracted increasing attention. This review mainly...
1-monosubstituted | Vinyl compounds | 1,2,3-triazole | Substituted acetylene | Acetylene | CONVENIENT SYNTHESIS | substituted acetylene | CATALYZED N-ARYLATION | CHEMISTRY, MEDICINAL | AZIDES | ACIDS | CLICK CHEMISTRY | ONE-POT | vinyl compounds | CALCIUM CARBIDE | ALKYNES | 1,3-DIPOLAR CYCLOADDITION | ARYL IODIDES | Vinyl Compounds - chemistry | Acetylene - chemistry | Triazoles - chemistry | Triazoles - chemical synthesis | Cycloaddition Reaction | Penicillanic Acid - chemical synthesis | Penicillanic Acid - chemistry | Penicillanic Acid - analogs & derivatives
1-monosubstituted | Vinyl compounds | 1,2,3-triazole | Substituted acetylene | Acetylene | CONVENIENT SYNTHESIS | substituted acetylene | CATALYZED N-ARYLATION | CHEMISTRY, MEDICINAL | AZIDES | ACIDS | CLICK CHEMISTRY | ONE-POT | vinyl compounds | CALCIUM CARBIDE | ALKYNES | 1,3-DIPOLAR CYCLOADDITION | ARYL IODIDES | Vinyl Compounds - chemistry | Acetylene - chemistry | Triazoles - chemistry | Triazoles - chemical synthesis | Cycloaddition Reaction | Penicillanic Acid - chemical synthesis | Penicillanic Acid - chemistry | Penicillanic Acid - analogs & derivatives
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 08/2013, Volume 2013, Issue 24, pp. 5272 - 5275
An efficient route for the synthesis of 2,4‐disubstituted 1,2,3‐triazoles by the regioselective direct arylation of 2‐aryl‐1,2,3‐triazole N‐oxides with Ar–X [X...
Arylation | C–H activation | Palladium | Nitrogen heterocycles | Regioselectivity | C-H activation | ACID | CHEMISTRY, ORGANIC | BOND FORMATION | BROMIDES | FUNCTIONALIZATION | LIGANDS | AZINE | ARYL CHLORIDES | CATALYZED DIRECT ARYLATION | Triazoles | Oxides
Arylation | C–H activation | Palladium | Nitrogen heterocycles | Regioselectivity | C-H activation | ACID | CHEMISTRY, ORGANIC | BOND FORMATION | BROMIDES | FUNCTIONALIZATION | LIGANDS | AZINE | ARYL CHLORIDES | CATALYZED DIRECT ARYLATION | Triazoles | Oxides
Journal Article
ISSN 1359-7345, 6/2014, Volume 5, Issue 54, pp. 7124 - 7127
A method for achieving the direct arylation of pyridines with phenylhydrazine hydrochloride was developed in this study. This new reaction proceeds readily at...
Journal Article
Progress in Chemistry, ISSN 1005-281X, 10/2012, Volume 24, Issue 10, pp. 1983 - 1994
Journal Article
15.
Full Text
Palladium-Catalyzed Olefination and Arylation of 2‑Substituted 1,2,3-Triazole N‑Oxides
Organic Letters, ISSN 1523-7060, 05/2013, Volume 15, Issue 10, pp. 2342 - 2345
Two highly efficient protocols for the regioselective synthesis of 2-substituted 4-alkenyl- and 4-aryl-1,2,3-triazoles by the palladium-catalyzed C–H...
ROOM-TEMPERATURE | PHOSPHINE-FREE | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | C-H BONDS | ARYL CHLORIDES | ALKENYLATION | Alkenes - chemistry | Cyclic N-Oxides - chemistry | Stereoisomerism | Triazoles - chemistry | Triazoles - chemical synthesis | Molecular Structure | Catalysis | Cyclic N-Oxides - chemical synthesis | Palladium - chemistry | Alkylation
ROOM-TEMPERATURE | PHOSPHINE-FREE | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | C-H BONDS | ARYL CHLORIDES | ALKENYLATION | Alkenes - chemistry | Cyclic N-Oxides - chemistry | Stereoisomerism | Triazoles - chemistry | Triazoles - chemical synthesis | Molecular Structure | Catalysis | Cyclic N-Oxides - chemical synthesis | Palladium - chemistry | Alkylation
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 12/2013, Volume 11, Issue 45, pp. 7830 - 7833
Journal Article
Cancer Science, ISSN 1347-9032, 08/2014, Volume 105, Issue 8, pp. 1008 - 1014
Whether S‐1 could replace 5‐Fluorouracil (5‐Fu) or not in the treatment of advanced gastrointestinal (GI) cancer (including advanced gastric cancer [AGS] and...
5‐Fluorouracil | S‐1 | meta‐analysis | chemotherapy | gastrointestinal cancer | Chemotherapy | 5-Fluorouracil | Gastrointestinal cancer | S-1 | Meta-analysis | TRIAL | LEUCOVORIN | THERAPY | ONCOLOGY | COLORECTAL-CANCER | meta-analysis | SOFT | Fluorouracil - therapeutic use | Asian Continental Ancestry Group | Oxonic Acid - therapeutic use | Gastrointestinal Neoplasms - drug therapy | Gastrointestinal Neoplasms - mortality | Humans | Tegafur - therapeutic use | Treatment Outcome | Antineoplastic Agents - therapeutic use | Drug Combinations | Randomized Controlled Trials as Topic | Cancer patients | Patient outcomes | Colorectal cancer | Comparative analysis | Fluorouracil | Cancer | Thrombocytopenia | Statistical analysis | Publications | Toxicity | Colorectal carcinoma | Clinical trials | Diarrhea | Nausea | Patients | Cancer therapies | Stomach cancer | Survival | Metastases | Studies | Platinum | Response rates | Gastric cancer | Potassium | Original
5‐Fluorouracil | S‐1 | meta‐analysis | chemotherapy | gastrointestinal cancer | Chemotherapy | 5-Fluorouracil | Gastrointestinal cancer | S-1 | Meta-analysis | TRIAL | LEUCOVORIN | THERAPY | ONCOLOGY | COLORECTAL-CANCER | meta-analysis | SOFT | Fluorouracil - therapeutic use | Asian Continental Ancestry Group | Oxonic Acid - therapeutic use | Gastrointestinal Neoplasms - drug therapy | Gastrointestinal Neoplasms - mortality | Humans | Tegafur - therapeutic use | Treatment Outcome | Antineoplastic Agents - therapeutic use | Drug Combinations | Randomized Controlled Trials as Topic | Cancer patients | Patient outcomes | Colorectal cancer | Comparative analysis | Fluorouracil | Cancer | Thrombocytopenia | Statistical analysis | Publications | Toxicity | Colorectal carcinoma | Clinical trials | Diarrhea | Nausea | Patients | Cancer therapies | Stomach cancer | Survival | Metastases | Studies | Platinum | Response rates | Gastric cancer | Potassium | Original
Journal Article
ISSN 1477-0520, 9/2014, Volume 12, Issue 38, pp. 7474 - 7477
A palladium-catalyzed ortho -acylation of 2-benzyl-1,2,3-triazoles with aldehydes as an acyl source was developed. A wide variety of ketones containing...
Journal Article
ISSN 1477-0520, 7/2014, Volume 12, Issue 33, pp. 6349 - 6353
A copper-catalyzed arylsulfonylation of N -arylsulfonyl-acrylamides with sulfonylhydrazides through a tandem radical process was developed. This methodology...
Journal Article
Synthesis, ISSN 0039-7881, 2010, Issue 2, pp. 283 - 287
Journal Article
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