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Science Translational Medicine, ISSN 1946-6234, 08/2017, Volume 9, Issue 402, p. eaai7993
Journal Article
HOMO - Journal of Comparative Human Biology, ISSN 0018-442X, 2005, Volume 56, Issue 2, pp. 119 - 132
This paper describes a quantitative approach to the assessment of dental calculus in human archaeological skeletal samples. The approach combines the ranked... 
PLAQUE | ANTHROPOLOGY | Severity of Illness Index | History, Ancient | Data Interpretation, Statistical | Age Factors | Dental Calculus - history | Humans | Male | Egypt, Ancient | Paleodontology | Diet - history | Sex Factors | Female | Tooth - pathology | Archaeology | Analysis | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2013, Volume 123, Issue 3, pp. 1348 - 1358
Journal Article
Cancer Research, ISSN 0008-5472, 11/2011, Volume 71, Issue 21, pp. 6773 - 6784
Estrogen receptor a (ER)-positive breast cancers adapt to hormone deprivation and become resistant to antiestrogens. In this study, we sought to identify... 
GROWTH-FACTOR RECEPTOR | ONCOLOGY | TAMOXIFEN | FACTOR-I/INSULIN RECEPTOR | DOWN-REGULATION | RESISTANCE | ENDOCRINE THERAPY | IGF | MONOCLONAL-ANTIBODY | TERM ESTROGEN DEPRIVATION | INHIBITOR | Estradiol - analogs & derivatives | Receptor, IGF Type 1 - antagonists & inhibitors | Adenocarcinoma - pathology | Insulin - physiology | Estrogens | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Cell Line, Tumor - drug effects | Pyrazines - therapeutic use | Receptors, Estrogen - analysis | Neoplasms, Hormone-Dependent - physiopathology | Breast Neoplasms - physiopathology | Estrogen Receptor Modulators - therapeutic use | Protein-Tyrosine Kinases - genetics | Adenocarcinoma - physiopathology | RNA Interference | Antineoplastic Agents, Hormonal - therapeutic use | Female | Adenocarcinoma - genetics | Imidazoles - therapeutic use | Estradiol - therapeutic use | Random Allocation | Receptor, Insulin - physiology | Receptor, Insulin - antagonists & inhibitors | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Disease-Free Survival | Animals | Breast Neoplasms - genetics | Insulin-Like Growth Factor I - physiology | Breast Neoplasms - pathology | Mice, Nude | Tamoxifen - therapeutic use | Receptor, IGF Type 1 - physiology | Neoplasm Proteins - analysis | Signal Transduction - physiology | Mice | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2013, Volume 123, Issue 10, pp. 4329 - 4343
Aberrant regulation of the erythroblastosis oncogene B (ErbB) family of receptor tyrosine kinases (RTKs) and their ligands is common in human cancers. ErbB3 is... 
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | GENE-EXPRESSION SIGNATURE | TYROSINE KINASE | EPIDERMAL-GROWTH-FACTOR | CARCINOMAS | FACTOR RECEPTOR | HEREGULIN | CANCER CELL-LINES | MAMMARY-GLAND | HER3 | Receptor, Epidermal Growth Factor - genetics | Estradiol - analogs & derivatives | Receptor, ErbB-3 - metabolism | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Receptor, ErbB-2 - genetics | Humans | Receptor, ErbB-2 - metabolism | Transcriptome | Drug Resistance, Neoplasm | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | MCF-7 Cells | Receptor, ErbB-3 - immunology | Female | Gene Expression Regulation, Neoplastic - drug effects | Estradiol - pharmacology | Gene Expression | Antineoplastic Agents, Hormonal - pharmacology | Signal Transduction | Cell Survival | Antibodies, Monoclonal - pharmacology | Gene Dosage | Receptor, ErbB-3 - genetics | Down-Regulation - drug effects | Breast Neoplasms - drug therapy | Estrogen Receptor Modulators - pharmacology | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Survival Analysis | Breast Neoplasms - mortality | Mice | Mice, Inbred BALB C | Care and treatment | Development and progression | Breast cancer | Research | Properties | Gene expression | Observations | Oncogenes | Cancer | Medical research | Kinases | Rodents | Tumors | Index Medicus | Abridged Index Medicus | Receptors d'hormones | Hormone receptors | Medicaments antineoplàstics | Estrogen | Càncer de mama | Antineoplastic agents | Expressió gènica | Estrògens
Journal Article
Cancer Research, ISSN 0008-5472, 07/2013, Volume 73, Issue 13, pp. 4075 - 4085
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2014, Volume 124, Issue 12, pp. 5490 - 5502
Estrogen receptor-positive (ER+) breast cancers adapt to hormone deprivation and become resistant to antiestrogen therapy. Here, we performed deep sequencing... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | NEOADJUVANT TREATMENT | AROMATASE INHIBITION | PHOSPHATIDYLINOSITOL 3-KINASE | TAMOXIFEN | THERAPEUTIC TARGET | IN-VIVO | ENDOCRINE THERAPY | SRC FAMILY KINASES | PHOSPHOINOSITIDE 3-KINASE | Gene Expression Regulation, Enzymologic - drug effects | Receptors, Estrogen - metabolism | Pyrimidines - agonists | Humans | Phosphatidylinositol 3-Kinases - metabolism | Mutation, Missense | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Thiazoles - agonists | Breast Neoplasms - metabolism | Phosphorylation - genetics | src-Family Kinases - metabolism | Morpholines - agonists | Female | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Aminopyridines - agonists | Gene Expression Regulation, Neoplastic - genetics | Dasatinib | Receptors, Estrogen - genetics | Morpholines - pharmacology | Pyrimidines - pharmacology | Breast Neoplasms - drug therapy | Estrogen Receptor Modulators - pharmacology | src Homology Domains | Drug Synergism | Phosphatidylinositol 3-Kinases - genetics | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Gene Expression Regulation, Enzymologic - genetics | Mice, Nude | Aminopyridines - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | src-Family Kinases - genetics | Amino Acid Substitution | Drug Resistance, Neoplasm - drug effects | Gene mutations | Estrogen | Physiological aspects | Breast cancer | Genetic aspects | Research | Health aspects | Risk factors | Medical research | Cell growth | Mutation | Kinases | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Discovery, ISSN 2159-8274, 02/2014, Volume 4, Issue 2, pp. 232 - 245
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2016, Volume 5, Issue 11, pp. 1092 - 1102
Abstract Objective The transcription factor cyclic AMP-responsive element-binding protein H (CREBH, encoded by Creb3l3 ) is highly expressed in the liver and... 
Endocrinology & Metabolism | CREBH | Intestine | Cholesterol | Npc1l1 | ABCG8 | LIPID ABSORPTION | NEUTRAL STEROL EXCRETION | ELEMENT-BINDING PROTEIN | HEPATIC CHOLESTEROL | RECEPTOR-ALPHA | CASSETTE TRANSPORTERS | ENDOCRINOLOGY & METABOLISM | GALLSTONE FORMATION | MICE | LITHOGENIC DIET | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4035 - 4045
Purpose: Because of inherent disease heterogeneity, targeted therapies have eluded triple-negative breast cancer (TNBC), and biomarkers predictive of treatment... 
TUMOR-INFILTRATING LYMPHOCYTES | MAMMALIAN TARGET | SURVIVAL | CHEMOSENSITIVITY | ALIGNMENT | ONCOLOGY | PROGRAMS | CLINICAL-TRIALS | FRAMEWORK | PATTERNS | CHEMOTHERAPY | DNA Damage - drug effects | Humans | Middle Aged | Paclitaxel - adverse effects | Treatment Outcome | Everolimus - administration & dosage | Triple Negative Breast Neoplasms - drug therapy | Cisplatin - administration & dosage | Drug-Related Side Effects and Adverse Reactions - pathology | Receptors, Androgen - genetics | Triple Negative Breast Neoplasms - genetics | Ki-67 Antigen - genetics | Lymphocytes, Tumor-Infiltrating - pathology | Drug-Related Side Effects and Adverse Reactions - genetics | Everolimus - adverse effects | Triple Negative Breast Neoplasms - pathology | Cisplatin - adverse effects | Adult | Female | High-Throughput Nucleotide Sequencing | Mutation | Neoplasm Staging | Paclitaxel - administration & dosage | TOR protein | Mesenchyme | DNA damage | Transaminase | Anticancer properties | Randomization | Lymphocytes | Surgery | Paclitaxel | Bioindicators | Deoxyribonucleic acid--DNA | Neutropenia | Mucositis | Tumor-infiltrating lymphocytes | Decision making | Exploration | Breast cancer | Patients | Cisplatin | Polymerase chain reaction | Correlation analysis | Biomarkers | Breast | Antitumor activity | Cancer | Index Medicus | mTOR inhibitor | breast cancer | chemotherapy
Journal Article
Cancer Discovery, ISSN 2159-8274, 09/2011, Volume 1, Issue 4, pp. 338 - 351
Journal Article
The Tohoku Journal of Experimental Medicine, ISSN 0040-8727, 2015, Volume 237, Issue 3, pp. 157 - 162
Surgeons often experience stress during operations. The heart rate variability (HRV) is the variability in the beat-to-beat interval, which has been used as... 
stress | autonomic nervous system | heart rate variability | surgical operation | surgeon | Surgical operation | Autonomic nervous system | Heart rate variability | Stress | Surgeon
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2013, Volume 123, Issue 3, p. 1348
  After an initial response to chemotherapy, many patients with triple-negative breast cancer (TNBC) have recurrence of drug-resistant metastatic disease.... 
Chemotherapy | Breast cancer | Genetic aspects | Research | Drug therapy | Transforming growth factors | Cancer
Journal Article
Topics in Catalysis, ISSN 1022-5528, 8/2003, Volume 23, Issue 1, pp. 163 - 173
Journal Article