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1. The collagens
: biochemistry and pathophysiology
by Kucharz, Eugene J. 1951- (Eugene Joseph)
1992, ISBN 9783540533238, xviii, 430
chemistry | physiopathology | Pathophysiology | Collagen | Collagen Diseases | physiology | Metabolism
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2. Statins therapy for connective tissue diseases: New therapeutic opportunities
by Kotyla, Przemyslaw J and Kucharz, Eugene J
Endocrine, Metabolic and Immune Disorders - Drug Targets, ISSN 1871-5303, 03/2018, Volume 18, Issue 2, pp. 135 - 147
Background and Objective: Statins, 3-hydroxyl-3-methyl-glutharyl Coenzyme A reductase inhibitors showed their therapeutic potential in the treatment of... 
Therapeutic | Connective tissue diseases | Immunomodulation | Pleiotropic effect | Statins | Mevalonate pathway | RHEUMATOID-ARTHRITIS | immunomodulation | pleiotropic effect | SYSTEMIC-LUPUS-ERYTHEMATOSUS | COENZYME-A REDUCTASE | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | IMMUNOLOGY | connective tissue diseases | therapeutic | MHC CLASS-I | MURINE MODEL | ENDOCRINOLOGY & METABOLISM | REGULATORY T-CELLS | GENE-EXPRESSION | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | CORONARY-HEART-DISEASE | Immune response | Cytokines | Laboratories | Medical treatment | Medical services | Clinical trials | Data processing | Inflammation | Database searching | Diseases | Mode of action | Scientific papers | Connective tissues | Immunology | Arteriosclerosis | Atherosclerosis | Fibrosis | Coenzyme A | Autoimmune diseases | Immune system | Reductase
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3. Full Text Serum concentration of surfactant protein D in patients with systemic sclerosis: The potential marker of the interstitial lung disease severity
by Grosicka, Anida and Manasar, Ahmed and Kucharz, Eugene J and Kotyla, Przemyslaw J
Best Practice & Research Clinical Rheumatology, ISSN 1521-6942, 08/2018, Volume 32, Issue 4, pp. 541 - 549
Pulmonary involvement is a severe manifestation of systemic sclerosis (SSc). The study was designed to determine the serum level of surfactant protein D (SP-D)... 
Systemic sclerosis-related interstitial lung disease | Interstitial lung disease | Serum surfactant protein D | Systemic sclerosis | BIOMARKERS | KL-6 | RHEUMATOLOGY | EULAR SCLERODERMA TRIALS | PULMONARY-FIBROSIS | Proteins | Care and treatment | Surface active agents | Systemic scleroderma | Analysis | Lung diseases | Scleroderma (Disease) | Pulmonary function tests
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4. Fibulin-3 and other cartilage metabolism biomarkers in relationship to calprotectin (MRP8/14) and disease activity in rheumatoid arthritis patients treated with anti-TNF therapy
by Kopec-Medrek, Magdalena and Kucharz, Eugene J
Advances in Clinical and Experimental Medicine, ISSN 1899-5276, 03/2018, Volume 27, Issue 3, pp. 383 - 389
Background. Fibulin-3 (Fib-3) is a new potential biomarker of articular cartilage metabolism. Objectives. The aim of the study was to evaluate the effect of... 
Rheumatoid arthritis | Calprotectin | Fibulin-3 | MEDICINE, RESEARCH & EXPERIMENTAL | calprotectin | BIOLOGICAL MARKERS | COHORT | OSTEOARTHRITIS | rheumatoid arthritis | fibulin-3 | Tumor Necrosis Factor-alpha - therapeutic use | Arthritis, Rheumatoid - blood | Arthritis, Rheumatoid - drug therapy | Humans | Female | Biomarkers - blood | Leukocyte L1 Antigen Complex - blood | Case-Control Studies | Extracellular Matrix Proteins - metabolism | Antirheumatic Agents - therapeutic use
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5. Statins Therapy for Connective Tissue Diseases: New Therapeutic Opportunities
by Kotyla, Przemyslaw J and Kucharz, Eugene J
Endocrine, metabolic & immune disorders drug targets, 02/2018, Volume 18, Issue 2, p. 135
Statins, 3-hydroxyl-3-methyl-glutharyl Coenzyme A reductase inhibitors showed their therapeutic potential in the treatment of atherosclerosis-related diseases.... 
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6. Full Text Opinion of patients with ankylosing spondylitis on risk factors impairing their quality of life
by Kucharz, Eugene J and Kucharz, Eugene J and Kotulska, Anna and Kotulska, Anna and Kopeć-Mędrek, Magdalena and Kopeć-Mędrek, Magdalena and Widuchowska, Małgorzata and Widuchowska, Małgorzata
Rheumatology International, ISSN 0172-8172, 11/2013, Volume 33, Issue 11, pp. 2899 - 2901
We studied 54 patients with ankylosing spondylitis with questionnaire in order to determine their view on threat to quality of their life related to the... 
Patients’ opinion | Medicine & Public Health | Ankylosing spondylitis | Rheumatology | Quality of life | Patients' opinion | RHEUMATOLOGY | Disability Evaluation | Severity of Illness Index | Humans | Middle Aged | Risk Factors | Male | Spondylitis, Ankylosing - complications | Patient Satisfaction | Disabled Persons - psychology | Pain - psychology | Pain - complications | Adult | Female | Surveys and Questionnaires | Quality of Life - psychology | Spondylitis, Ankylosing - psychology | Health Status | Risk factors | Short Communication
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7. Full Text Update of EULAR recommendations for the treatment of systemic sclerosis
by Kowal-Bielecka, Otylia and Fransen, Jaap and Avouac, Jerome and Becker, Mike and Kulak, Agnieszka and Allanore, Yannick and Distler, Oliver and Clements, Philip and Cutolo, Maurizio and Czirjak, Laszlo and Damjanov, Nemanja and del Galdo, Francesco and Denton, Christopher P and Distler, Jörg H W and Foeldvari, Ivan and Figelstone, Kim and Frerix, Marc and Furst, Daniel E and Guiducci, Serena and Hunzelmann, Nicolas and Khanna, Dinesh and Matucci-Cerinic, Marco and Herrick, Ariane L and van den Hoogen, Frank and van Laar, Jacob M and Riemekasten, Gabriela and Silver, Richard and Smith, Vanessa and Sulli, Alberto and Tarner, Ingo and Tyndall, Alan and Welling, Joep and Wigley, Frederic and Valentini, Gabriele and Walker, Ulrich A and Zulian, Francesco and Müller-Ladner, Ulf and EUSTAR Coauthors and Department of Rheumatology and Lund University and Lund Systemic Sclerosis Research Group and Forskargruppen för systemisk skleros, Lund and Reumatologi och molekylär skelettbiologi and Hjärt-lungsjukdom - information, stöd och bemötande and Lunds universitet and Cardiopulmonary disease - information, support and reception
Annals of the Rheumatic Diseases, ISSN 0003-4967, 08/2017, Volume 76, Issue 8, pp. 1327 - 1339
The aim was to update the 2009 European League against Rheumatism (EULAR) recommendations for the treatment of systemic sclerosis (SSc), with attention to new... 
Systemic Sclerosis | Cyclophosphamide | Treatment | Methotrexate | ORAL PROSTACYCLIN ANALOG | SCLERODERMA RENAL CRISIS | DIGITAL ULCERS | DOUBLE-BLIND TRIAL | PULMONARY ARTERIAL-HYPERTENSION | INTESTINAL BACTERIAL OVERGROWTH | INTRAVENOUS EPOPROSTENOL | RAYNAUDS-PHENOMENON SECONDARY | STANDARDIZED OPERATING PROCEDURES | RHEUMATOLOGY | STEM-CELL TRANSPLANTATION | Glucocorticoids - therapeutic use | Pyrazoles - therapeutic use | Humans | Gastrointestinal Diseases - etiology | Lung Diseases - therapy | Raynaud Disease - etiology | Hypertension, Pulmonary - therapy | Lung Diseases - etiology | Scleroderma, Systemic - therapy | Delphi Technique | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Raynaud Disease - therapy | Fingers | Scleroderma, Systemic - complications | Phosphodiesterase 5 Inhibitors - therapeutic use | Fluoxetine - therapeutic use | Ulcer - etiology | Ulcer - therapy | Europe | Rheumatology | Serotonin Uptake Inhibitors - therapeutic use | Hematopoietic Stem Cell Transplantation | Gastrointestinal Diseases - therapy | Prostaglandins I - therapeutic use | Pyrimidines - therapeutic use | Kidney Diseases - therapy | Kidney Diseases - etiology | Endothelin Receptor Antagonists - therapeutic use | Hypertension, Pulmonary - etiology | Endothelin | Experts | Fluoxetine | Lung diseases | Clinical trials | Stem cell transplantation | Transplantation | Prostacyclin | Patients | Literature reviews | Studies | Systemic sclerosis | Ulcers | Skin diseases | Scleroderma | Phosphodiesterase | Kidney transplantation | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
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8. Full Text Witold orlowski - Prominent polish internist (Mayo Clinic Proceedings (2007) 82, 9, (1037))
by Kucharz, Eugene J
Mayo Clinic Proceedings, ISSN 0025-6196, 2008, Volume 83, Issue 4, p. 507
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9. Full Text Tumor necrosis factor-α as a potential target in the treatment of systemic lupus erythematosus: A role for the HMG-CoA reductase inhibitor simvastatin [3]
by Kotyla, Przemyslaw J and Sliwinska-Kotyla, Bogna and Kucharz, Eugene J
Journal of Rheumatology, ISSN 0315-162X, 11/2006, Volume 33, Issue 11, pp. 2361 - 2363
Atherosclerosis - etiology | Simvastatin - therapeutic use | Lupus Erythematosus, Systemic - complications | Atherosclerosis - drug therapy | Tumor Necrosis Factor-alpha - drug effects | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Middle Aged | Lupus Erythematosus, Systemic - drug therapy | Adult | Female
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10. Full Text Plasma leptin and neuropeptide Y concentrations in patients with rheumatoid arthritis treated with infliximab, a TNF-[alpha] antagonist
by Kopec-Medrek, Magdalena and Kotulska, Anna and Widuchowska, Malgorzata and Adamczak, Marcin and WiAcek, Andrzej and Kucharz, Eugene J
Rheumatology International, ISSN 0172-8172, 11/2012, Volume 32, Issue 11, p. 3383
TNF-α is one of the key proinflammatory cytokines in pathogenesis of rheumatoid arthritis (RA). TNF-α was also found to enhance synthesis of leptin. Leptin is... 
Neuropeptide Y | Rheumatoid factor | Care and treatment | Infliximab | Tumor necrosis factor | Leptin | Rheumatoid arthritis | Physiological aspects
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11. Full Text A review of glucosamine for knee osteoarthritis: why patented crystalline glucosamine sulfate should be differentiated from other glucosamines to maximize clinical outcomes
by Kucharz, Eugene J and Kovalenko, Volodymyr and Szántó, Sándor and Bruyère, Olivier and Cooper, Cyrus and Reginster, Jean-Yves
Current Medical Research and Opinion, ISSN 0300-7995, 06/2016, Volume 32, Issue 6, pp. 997 - 1004
The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm for knee osteoarthritis (OA) recommends... 
Osteoarthritis | Glucosamine | Symptomatic slow-acting drugs for osteoarthritis | MEDICINE, RESEARCH & EXPERIMENTAL | CHONDROITIN SULFATE | MANAGEMENT | CHONDROCYTES | CARTILAGE EXPLANTS | MEDICINE, GENERAL & INTERNAL | TASK-FORCE | RECOMMENDATIONS | PLACEBO-CONTROLLED TRIALS | DOUBLE-BLIND | TOTAL JOINT REPLACEMENT | PROGRESSION | Nonprescription Drugs - therapeutic use | Glucosamine - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Pain - drug therapy | Humans | Acetaminophen - therapeutic use | Dietary Supplements | Disease Progression | Osteoarthritis, Knee - drug therapy
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12. Full Text Tumor necrosis factor associated periodic syndrome in a family from Silesia
by Kotulska, Anna and Ciechanowicz, Andrzej and Bińczak-Kuleta, Agnieszka and Ostanek-Pańka, Magdalena and Kopeć-Mędrek, Magdalena and Rudka, Roman
European Journal of Internal Medicine, ISSN 0953-6205, 2013, Volume 24, pp. e131 - e131
Internal Medicine | Tumor necrosis factor | Tumors
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13. Full Text Chikungunya fever
by Kucharz, Eugene J and Cebula-Byrska, Ilona
European Journal of Internal Medicine, ISSN 0953-6205, 2012, Volume 23, Issue 4, pp. 325 - 329
Abstract Chikungunya fever (CF) is an acute illness caused by Chikungunya virus (CHIKV) belonging to the alphavirus genus of the Alphaviruses (Togaviridae)... 
Internal Medicine | Viral arthritis | Chikungunya fever | Chikungunya virus | MEDICINE, GENERAL & INTERNAL | IMMUNOGENICITY | VIRUS-INFECTION | REUNION ISLAND | EPIDEMIC | ARTHRITIS | OUTBREAK | MANIFESTATIONS | Alphavirus Infections - diagnosis | Chikungunya Fever | Animals | Insect Vectors | Humans | Alphavirus Infections - transmission | Alphavirus Infections - therapy | Aedes | Rheumatoid factor | Mosquitoes | Antirheumatic agents | Disease transmission | Rheumatoid arthritis | Arthritis | Health aspects
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14. Full Text The First and Second Solemn Meeting of the Polish Internists
by Kucharz, Eugene J
European Journal of Internal Medicine, ISSN 0953-6205, 2008, Volume 19, Issue 8, pp. 633 - 635
Internal Medicine
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15. Full Text Infliximab treatment increases left ventricular ejection fraction in patients with rheumatoid arthritis: Assessment of heart function by echocardiography, endothelin 1, interleukin 6, and NT-pro brain natriuretic peptide
by Kotyla, Przemyslaw J and Owczarek, Aleksander and Rakoczy, Jaroslaw and Lewicki, Maciej and Kucharz, Eugene J and Emery, Paul
Journal of Rheumatology, ISSN 0315-162X, 04/2012, Volume 39, Issue 4, pp. 701 - 706
Objective. To study the influence of anti-tumor necrosis factor-alpha (TNF-alpha) treatment on echocardiographic measures and concentrations of endothelin 1... 
Heart failure | Endothelin 1 | Infliximab | NT-pro brain natriuretic peptide | Rheumatoid arthritis | EARLY-DIAGNOSIS | HEART FAILURE | ENDOTHELIN 1 | PREVALENCE | RHEUMATOLOGY | FAILURE | DISEASE-ACTIVITY | TUMOR-NECROSIS-FACTOR | THERAPY | RHEUMATOID ARTHRITIS | NT-PRO BRAIN NATRIURETIC PEPTIDE | TNF-ALPHA | DYSFUNCTION | INFLIXIMAB | BLOCKADE | ASSOCIATION | Antibodies, Monoclonal - pharmacology | Humans | Middle Aged | Heart Failure - physiopathology | Stroke Volume - immunology | Stroke Volume - drug effects | Natriuretic Peptide, Brain - pharmacology | Arthritis, Rheumatoid - complications | Ventricular Dysfunction, Left - diagnostic imaging | Ventricular Dysfunction, Left - physiopathology | Heart Failure - drug therapy | Ventricular Dysfunction, Left - drug therapy | Arthritis, Rheumatoid - drug therapy | Ultrasonography | Female | Antirheumatic Agents - pharmacology | Heart Failure - diagnostic imaging | Arthritis, Rheumatoid - physiopathology | Cohort Studies
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16. Full Text Ninth Polish–Slovak Conference on Internal Medicine Woźniki near Częstochowa, March 28–29, 2008
by Kucharz, Eugene J
European Journal of Internal Medicine, ISSN 0953-6205, 2008, Volume 20, Issue 1, pp. 94 - 95
Internal Medicine
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17. Full Text Digital ulcers predict a worse disease course in patients with systemic sclerosis
by Mihai, Carina and Landewé, Robert and van der Heijde, Désirée and Walker, Ulrich A and Constantin, Paul I and Gherghe, Ana Maria and Ionescu, Ruxandra and Rednic, Simona and Allanore, Yannick and Avouac, Jérôme and Czirják, László and Hachulla, Eric and Riemekasten, Gabriela and Cozzi, Franco and Airò, Paolo and Cutolo, Maurizio and Mueller-Ladner, Ulf and Matucci-Cerinic, Marco and EUSTAR and EUSTAR co-authors
Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2016, Volume 75, Issue 4, pp. 681 - 686
ObjectiveSystemic sclerosis (SSc) is a systemic autoimmune disease with high morbidity and significant mortality. There is a great need of predictors that... 
ORGAN INVOLVEMENT | RISK-FACTORS | DATABASE | 5-YEAR SURVIVAL | COHORT | MODEL | RHEUMATOLOGY | EULAR SCLERODERMA TRIALS | LESIONS | Care and treatment | Usage | Systemic scleroderma | Mortality | Analysis | Scleroderma (Disease) | Ultrasonic waves | Outcome and process assessment (Health Care) | Hypertension | Studies | Heart failure | Ultrasonic imaging | Medical prognosis | Clinical medicine | Scleroderma | Patients | Data bases
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18. Full Text Second European Day of Internal Medicine of the European Federation of Internal Medicine
by Kucharz, Eugene J
European Journal of Internal Medicine, ISSN 0953-6205, 2008, Volume 19, Issue 8, pp. 630 - 632
Internal Medicine
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19. Full Text Stamp vignette on medical science. Witold Orlowski--prominent Polish internist
by Kurcharz, Eugene J and Shampo, Marc A and Kyle, Robert A
Mayo Clinic proceedings. Mayo Clinic, ISSN 0025-6196, 2007, Volume 82, Issue 9, p. 1037
Poland | History, 20th Century | Humans | Internal Medicine - history | Philately
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20. Full Text Prediction of improvement in skin fibrosis in diffuse cutaneous systemic sclerosis: a EUSTAR analysis
by Dobrota, Rucsandra and Maurer, Britta and Graf, Nicole and Jordan, Suzana and Mihai, Carina and Kowal-Bielecka, Otylia and Allanore, Yannick and Distler, Oliver and EUSTAR Coauthors
Annals of the Rheumatic Diseases, ISSN 0003-4967, 10/2016, Volume 75, Issue 10, pp. 1743 - 1748
ObjectivesImprovement of skin fibrosis is part of the natural course of diffuse cutaneous systemic sclerosis (dcSSc). Recognising those patients most likely to... 
RANDOMIZED CONTROLLED-TRIALS | SCORE | RESEARCH GROUP DATABASE | CLINICAL-TRIALS | DISEASE | Systemic Sclerosis | DOUBLE-BLIND | RHEUMATOLOGY | Outcomes research | Epidemiology | EULAR SCLERODERMA TRIALS | D-PENICILLAMINE | Clinical and Epidemiological Research | 1507 | 1506
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