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BMC Cancer, ISSN 1471-2407, 08/2018, Volume 18, Issue 1, pp. 1 - 16
...Author(s): Melanie Kucherlapati[sup.1,2] Background Comparatively uncontrolled replication carried out by highly evolutionarily conserved multiprotein... 
Uveal melanoma | Replication | Repair | Expression | STRAND BREAK REPAIR | FORK | PCNA | CANCER | DEFICIENCY | MAINTENANCE | NUCLEAR-MATRIX | ONCOLOGY | FACTOR CIZ1 | INTEGRATIVE GENOMICS VIEWER | MCM2 | Care and treatment | DNA replication | Usage | Analysis | Melanoma | Genetic aspects | Genetic transcription | Research | Gene expression | DNA repair
Journal Article
Oncotarget, ISSN 1949-2553, 12/2019, Volume 10, Issue 65, pp. 6913 - 6933
Genes of the pre-replication, pre-initiation and replisome complexes duplicate the genome from many sites once in a normal cell cycle. This study examines... 
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e44273
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2000, Volume 6, Issue 9, pp. 991 - 997
Journal Article
Cell Reports, ISSN 2211-1247, 07/2018, Volume 24, Issue 2, pp. 515 - 527
A systematic cataloging of genes affected by genomic rearrangement, using multiple patient cohorts and cancer types, can provide insight into cancer-relevant... 
genomic rearrangement | whole genome sequencing | structural variation | cancer | pan-cancer | TCGA | ATLAS | TAXONOMY | IMPACT | ACTIVATION | LANDSCAPE | STRUCTURAL VARIATIONS | PATTERNS | MUTATIONS | CELL BIOLOGY
Journal Article
by Kim, Jihun and Bowlby, Reanne and Mungall, Andrew J and Robertson, A. Gordon and Odze, Robert D and Cherniack, Andrew D and Shih, Juliann and Pedamallu, Chandra Sekhar and Cibulskis, Carrie and Dunford, Andrew and Meier, Samuel R and Kim, Jaegil and Raphael, J and Wu, Hsin-Ta and Wong, Alexandra M and Willis, Joseph E and Bass, Adam J and Derks, Sarah and Garman, Katherine and McCall, Shannon J and Wiznerowicz, MacIej and Pantazi, Angeliki and Parfenov, Michael and Thorsson, Vésteinn and Shmulevich, Ilya and Dhankani, Varsha and Miller, Michael and Sakai, Ku Leuven Ryo and Wang, Kenneth and Schultz, Nikolaus and Shen, Ronglai and Arora, Arshi and Weinhold, Nils and Sánchez-Vega, Francisco and Kelsen, David P and Zhang, Julia and Felau, Ina and Demchok, John and Rabkin, Charles S and Camargo, M. Constanza and Zenklusen, Jean Claude and Bowen, Jay and Leraas, Kristen and Lichtenberg, Tara M and Curtis, Christina and Seoane, Jose A and Ojesina, Akinyemi I and Beer, David G and Gulley, Margaret L and Pennathur, Arjun and Luketich, James D and Zhou, Zhongren and Weisenberger, Daniel J and Akbani, Rehan and Lee, Ju-Seog and Liu, Wenbin and Mills, Gordon B and Zhang, Wei and Reid, Brian J and Hinoue, Toshinori and Laird, Peter W and Shen, Hui and Piazuelo, M. Blanca and Schneider, Barbara G and McLellan, Michael and Taylor-Weiner, Amaro and Lawrence, Michael and Cibulskis, Kristian and Stewart, Chip and Getz, Gad and Lander, Eric and Gabriel, Stacey B and DIng, Li and McLellan, Michael D and Miller, Christopher A and Appelbaum, Elizabeth L and Cordes, Matthew G and Fronick, Catrina C and Fulton, Lucinda A and Mardis, Elaine R and Wilson, Richard K and Schmidt, Heather K and Fulton, Robert S and Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Holt, Robert A and Jones, Steven J. M and Kasaian, Katayoon and Brooks, Denise and Li, Haiyan I and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Karen L and Schein, Jacqueline E and Sipahimalani, Payal and ... and Canc Genome Atlas Res Network and Data Coordination Center: CSRA Inc and Duke University and Ribeirão Preto Medical School and Israelitisches Krankenhaus Hamburg and Project Team: National Institutes of Health and Tissue Source Sites: Analytic Biologic Services and Nationwide Children’s Hospital and Greater Poland Cancer Centre and Brown University and University of Michigan and Mayo Clinic and Broad Institute and Keimyung University School of Medicine and Asan Medical Center and Barretos Cancer Hospital and University of Alabama and Indiana University School of Medicine and Invidumed and National Cancer Center Goyang and Yonsei University College of Medicine and Vanderbilt University and University of North Carolina at Chapel Hill and Cureline and Cancer Genome Atlas Research Network and Institute of Oncology of Moldova and University of Pittsburgh School of Medicine and University of Pittsburgh and Genome Characterization Centers: BC Cancer Agency and Analysis Working Group: Asan University and University of Texas MD Anderson Cancer Center and Case Western Reserve University and National Cancer Institute and Genome Data Analysis Centers: Broad Institute and St. Joseph’s Hospital &Medical Center and University of Southern California and Institute for Systems Biology and Ontario Tumour Bank and University of Washington and University of Rochester and Harvard Medical School and KU Leuven and Genome Sequencing Center: Broad Institute and Brigham and Women’s Hospital and Memorial Sloan Kettering Cancer Center and Disease Working Group: Duke University and Erasmus University and Christiana Care Health System and University of Kansas Medical Center and Research Institute at Nationwide Children’s Hospital and International Genomics Consortium and Tayside Tissue Bank and Peter MacCallum Cancer Centre and Pusan National University Medical School and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University and BioreclamationIVT and Dana-Farber Cancer Institute and University of Southern California Epigenome Center and Stanford University and BC Cancer Agency and Chonnam National University Medical School and St. Petersburg Academic University and University of North Carolina and University of Dundee and Van Andel Research Institute and Washington University in St. Louis and Emory University and Washington University and University of California Santa Cruz and Biospecimen Core Resource: International Genomics Consortium and Asterand Bioscience and Botkin Municipal Clinic and The Cancer Genome Atlas Research Network
Nature (London), ISSN 0028-0836, 01/2017, Volume 541, Issue 7636, pp. 169 - 174
Journal Article
Journal Article
Gut, ISSN 0017-5749, 12/2015, Volume 64, Issue 12, pp. 1905 - 1912
ObjectiveLynch syndrome is caused by germline mutations in DNA mismatch repair genes leading to microsatellite instability (MSI) and colorectal cancer.... 
Mesalamine | Treatment outcome | Care and treatment | Dosage and administration | Analysis | Colorectal cancer | Cell growth | Mutation | Kinases | Small intestine | Rodents | 1507 | GI cancer | 1506
Journal Article
by Raphael, Benjamin J and Hruban, Ralph H and Aguirre, Andrew J and Moffitt, Richard A and Yeh, Jen Jen and Stewart, Chip and Robertson, A. Gordon and Cherniack, Andrew D and Gupta, Manaswi and Getz, Gad and Gabriel, Stacey B and Meyerson, Matthew and Cibulskis, Carrie and Fei, Suzanne S and Hinoue, Toshinori and Shen, Hui and Laird, Peter W and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Akbani, Rehan and Loher, Phillipe and Londin, Eric R and Rigoutsos, Isidore and Telonis, Aristeidis G and Gibb, Ewan A and Goldenberg, Anna and Mezlini, Aziz M and Hoadley, Katherine A and Collisson, Eric and Lander, Eric and Murray, Bradley A and Hess, Julian and Rosenberg, Mara and Bergelson, Louis and Zhang, Hailei and Cho, Juok and Tiao, Grace and Kim, Jaegil and Livitz, Dimitri and Leshchiner, Ignaty and Reardon, Brendan and Van Allen, Eliezer and Kamburov, Atanas and Beroukhim, Rameen and Saksena, Gordon and Schumacher, Steven E and Noble, Michael S and Heiman, David I and Gehlenborg, Nils and Lawrence, Michael S and Adsay, Volkan and Petersen, Gloria and Klimstra, David and Bardeesy, Nabeel and Leiserson, Mark D.M and Bowlby, Reanne and Kasaian, Katayoon and Birol, Inanc and Mungall, Karen L and Sadeghi, Sara and Weinstein, John N and Spellman, Paul T and Liu, Yuexin and Amundadottir, Laufey T and Tepper, Joel and Singhi, Aatur D and Dhir, Rajiv and Paul, Drwiega and Smyrk, Thomas and Zhang, Lizhi and Kim, Paula and Bowen, Jay and Frick, Jessica and Gastier-Foster, Julie M and Gerken, Mark and Lau, Kevin and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Renkel, Jeremy and Sherman, Mark and Wise, Lisa and Yena, Peggy and Zmuda, Erik and Shih, Juliann and Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chu, Andy and Chuah, Eric and Clarke, Amanda and Dhalla, Noreen and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network. Electronic address: andrew_aguirre@dfci.harvard.edu and Cancer Genome Atlas Research Network
Cancer Cell, ISSN 1535-6108, 08/2017, Volume 32, Issue 2, pp. 185 - 203.e13
Journal Article