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humans (55) 55
oncology (42) 42
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risk factors (21) 21
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unfractionated heparin (5) 5
venous thromboembolism - complications (5) 5
warfarin (5) 5
antineoplastic combined chemotherapy protocols - adverse effects (4) 4
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chemotherapy, adjuvant (4) 4
cost-benefit analysis (4) 4
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dose-response relationship, drug (4) 4
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neoplasms - blood (4) 4
neoplasms - therapy (4) 4
neutropenia - economics (4) 4
predictive value of tests (4) 4
reproducibility of results (4) 4
abridged index medicus (3) 3
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1. Full Text Reply to M.G. McNamara et al and T.H. Oo
by Lyman, Gary H and Kuderer, Nicole M
Journal of Clinical Oncology, ISSN 0732-183X, 02/2016, Volume 34, Issue 5, pp. 517 - 518
Pancreatic Neoplasms - drug therapy | Female | Male | Heparin, Low-Molecular-Weight - administration & dosage | Humans
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2. Full Text Safety and Effectiveness of Rivaroxaban Versus Low Molecular Weight Heparin for Treatment of Cancer-Associated Venous Thrombosis: A SEER-Medicare-Linked Data Analysis
by Kohn, Christine G and Lyman, Gary H and Kuderer, Nicole M and Bunz, Thomas J and Coleman, Craig I
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3673 - 3673
Introduction: Venous thromboembolism (VTE) affects ~20% of patients with cancer prior to death and may be present in up to half of cancer patients upon... 
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3. Full Text A meta-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: Impact on survival and bleeding complications
by Kuderer, Nicole M and Khorana, Alok A and Lyman, Gary H and Francis, Charles W
Cancer, ISSN 0008-543X, 09/2007, Volume 110, Issue 5, pp. 1149 - 1161
BACKGROUND. Preclinical evidence Suggests that anticoagulants, in particular the low-molecular-weight heparins (LMWH), exert an antitumor effect, whereas clini... 
Warfarin | Mortality | Heparin | Low-molecular-weight heparin | Hemorrhage | Survival | Thrombosis | Neoplasms | Meta-analysis | Randomized controlled trials | LEUKEMIA GROUP-B | survival | meta-analysis | LOW-MOLECULAR-WEIGHT | DEEP-VEIN THROMBOSIS | randomized controlled trials | RANDOMIZED CLINICAL-TRIALS | INDIVIDUAL PATIENT DATA | WALKER-256 CARCINOSARCOMA | warfarin | heparin | CELL LUNG-CANCER | thrombosis | VENOUS THROMBOEMBOLISM | ONCOLOGY | COLORECTAL-CANCER | mortality | low-molecular-weight heparin | VASCULAR ENDOTHELIAL-CELLS | neoplasms | hemorrhage | Humans | Survival Analysis | Heparin, Low-Molecular-Weight - adverse effects | Warfarin - adverse effects | Anticoagulants - therapeutic use | Treatment Outcome | Hemorrhage - chemically induced | Anticoagulants - adverse effects | Heparin, Low-Molecular-Weight - therapeutic use | Neoplasms - drug therapy | Randomized Controlled Trials as Topic | Warfarin - therapeutic use | Evaluation | Usage | Cancer patients | Care and treatment | Physiological aspects | Anticoagulants (Medicine) | Research | Drug therapy | Health aspects | Cancer
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4. Full Text Evolving landscape of US food and drug administration drug approval in the era of precision oncology: Finding the right balance between access and safety
by Kuderer, Nicole M and Lyman, Gary H
Journal of Clinical Oncology, ISSN 0732-183X, 06/2018, Volume 36, Issue 18, pp. 1773 - 1776
BREAST-CANCER | CANCER CLINICAL-TRIALS | ONCOLOGY | RESPONSE RATE | END-POINTS | EXPERIENCE | ACCELERATED APPROVAL | SUPPRESSION | ASSOCIATION | SYMPTOMATIC ADVERSE EVENTS | PATIENT-REPORTED OUTCOMES | United States | Humans | Antineoplastic Agents | Drug Approval | Neoplasms | United States Food and Drug Administration | Precision Medicine | Randomized Controlled Trials as Topic
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5. Full Text Direct oral anticoagulant for the prevention of thrombosis in ambulatory patients with cancer: A systematic review and meta‐analysis
by Li, Ang and Kuderer, Nicole M and Garcia, David A and Khorana, Alok A and Wells, Philip S and Carrier, Marc and Lyman, Gary H
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 12/2019, Volume 17, Issue 12, pp. 2141 - 2151
Background It is unclear if direct oral anticoagulant (DOAC) is efficacious and safe for prophylaxis of venous thromboembolism (VTE) in ambulatory patients... 
neoplasm | rivaroxaban | factor Xa inhibitors | apixaban | venous thromboembolism
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6. Full Text The Rate of Venous Thromboembolism in Cancer Patients Varies By Khorana Risk Category
by Khorana, Alok A and Kuderer, Nicole M and McCrae, Keith R and Milentijevic, Dejan and Germain, Guillaume and Laliberté, François and Le, Nguyen and Lefebvre, Patrick and Lyman, Gary H and Streiff, Michael B
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3798 - 3798
Abstract Introduction: Venous thromboembolism (VTE) is common in cancer patients and associated with adverse consequences. Risk factors for cancer-associated... 
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7. Full Text Healthcare Costs in Patients with Cancer Increase with Increasing Risk of Venous Thromboembolism
by Streiff, Michael B and McCrae, Keith R and Kuderer, Nicole M and Milentijevic, Dejan and Germain, Guillaume and Laliberté, François and Le, Nguyen and Lefebvre, Patrick and Lyman, Gary H and Khorana, Alok A
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3799 - 3799
Abstract Introduction: Venous thromboembolism (VTE) is a cause of significant morbidity and mortality in cancer patients and its prevalence in this population... 
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8. Full Text Meta-Analysis and Cost-Effectiveness Analysis of Low-Dose Direct Oral Anticoagulant for the Prevention of Cancer Associated Thrombosis
by Li, Ang and Carlson, Josh J and Kuderer, Nicole M and Schaefer, Jordan K and Li, Shan and Garcia, David A and Khorana, Alok A and Carrier, Marc and Lyman, Gary H
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4669 - 4669
Introduction: Randomized controlled trials (RCTs) have shown similar yet conflicting primary outcomes for the use of low-dose direct oral anticoagulant (DOAC),... 
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9. Full Text Impact of a 21-gene RT-PCR assay on treatment decisions in early-stage breast cancer: An economic analysis based on prognostic and predictive validation studies
by Lyman, Gary H and Cosler, Leon E and Kuderer, Nicole M and Hornberger, John
Cancer, ISSN 0008-543X, 03/2007, Volume 109, Issue 6, pp. 1011 - 1018
BACKGROUND. The prognostic accuracy for distant recurrence-free survival using a 21-gene reverse-transcriptase polymerase chain reaction (RT-PCR) assay... 
Economic analysis | Adjuvant chemotherapy | Costs | Lymph node-negative | 21-gene RT-PCR | Breast cancer | Microarray | Tamoxifen | Estrogen receptor-positive | COST-EFFECTIVENESS ANALYSIS | adjuvant chemotherapy | costs | SURGICAL ADJUVANT BREAST | economic analysis | GENE-EXPRESSION PATTERNS | breast cancer | RANDOMIZED CLINICAL-TRIALS | CHEMOTHERAPY | microarray | THERAPY | estrogen receptor-positive | ONCOLOGY | ADJUSTED SURVIVAL | RECURRENCE | QUALITY-OF-LIFE | tamoxifen | lymph node-negative | Gene Expression | Lymph Nodes - pathology | Prognosis | Humans | RNA, Messenger - analysis | Treatment Outcome | Neoplasm Recurrence, Local - diagnosis | Breast Neoplasms - drug therapy | Neoplasm Recurrence, Local - pathology | Disease-Free Survival | Reverse Transcriptase Polymerase Chain Reaction - economics | Breast Neoplasms - pathology | Antineoplastic Agents, Hormonal - therapeutic use | Cost-Benefit Analysis | Reverse Transcriptase Polymerase Chain Reaction - methods | Tamoxifen - therapeutic use | Female | Breast Neoplasms - diagnosis | Chemotherapy, Adjuvant | Monte Carlo Method | Polymerase chain reaction | Care and treatment | DNA microarrays | Analysis | Genetic aspects | Research
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10. Full Text Morbidity, Mortality and Costs Associated with Venous Thromboembolism in Hospitalized Patients with Cancer
by Lyman, Gary H and Culakova, Eva and Poniewierski, Marek S and Kuderer, Nicole M
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 4751 - 4751
Background: Venous thromboembolism (VTE) represents a leading cause of morbidity and mortality among hospitalized patients with cancer. Methods:... 
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11. Full Text Rumors of the Death of Biosimilars Have Been Greatly Exaggerated
by Lyman, Gary H and Kuderer, Nicole M
Cancer investigation, 09/2019, p. 1
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12. Full Text Use of biomarkers to guide decisions on adjuvant systemic therapy forwomenwith early-stage invasive breast cancer: American Society of clinical Oncology clinical practice guideline
by Harris, Lyndsay N and Ismaila, Nofisat and McShane, Lisa M and Andre, Fabrice and Collyar, Deborah E and Gonzalez-Angulo, Ana M and Hammond, Elizabeth H and Kuderer, Nicole M and Liu, Minetta C and Mennel, Robert G and Van Poznak, Catherine and Bast, Robert C and Hayes, Daniel F
Journal of Clinical Oncology, ISSN 0732-183X, 04/2016, Volume 34, Issue 10, pp. 1134 - 1150
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13. Full Text Application of a Validated Predictive Model for Venous Thromboembolism in Cancer to Patients with Multiple Myeloma
by Edwin, Natasha Catherine and Keller, Jesse and Luo, Suhong and Carson, Kenneth R and Gage, Brian F and Kuderer, Nicole M and Calverley, David and Sanfilippo, Kristen M
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 534 - 534
Abstract Background Patients with multiple myeloma (MM) have a 9-fold increased risk of developing venous thromboembolism (VTE). Current guidelines recommend... 
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14. Full Text Thromboembolic events (TE) among patients with metastatic pancreatic ductal adenocarcinoma (mPDA) after chemotherapy (Chemo)
by Lyman, Gary H and Schabert, Vernon F and Philip, Philip Agop and Stokes, Michael and Bhurke, Sharvari and Kuderer, Nicole M and Qadan, Ammar and Khorana, Alok A
Journal of Clinical Oncology, ISSN 0732-183X, 02/2017, Volume 35, Issue 4_suppl, pp. 280 - 280
280 Background: Clinical trials suggest that patients with mPDA are at high risk of TE from both disease and treatment. TE rates and anticoagulant use among... 
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15. Full Text Morbidity, Mortality and Costs Associated with Venous Thromboembolism in Hospitalized Patients with Cancer
by Lyman, Gary H and Culakova, Eva and Poniewierski, Marek S and Kuderer, Nicole M
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 2613 - 2613
Background: Venous thromboembolism (VTE) occurs commonly in patients with cancer and is associated with considerable morbidity and mortality. While the risk of... 
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16. Full Text Impact of Primary Prophylaxis With Granulocyte Colony-Stimulating Factor on Febrile Neutropenia and Mortality in Adult Cancer Patients Receiving Chemotherapy: A Systematic Review
by Nicole M. Kuderer and David C. Dale and Jeffrey Crawford and Gary H. Lyman
Journal of Clinical Oncology, ISSN 0732-183X, 07/2007, Volume 25, Issue 21, pp. 3158 - 3167
Purpose Randomized controlled trials ( RCTs) of prophylactic granulocyte colony-stimulating factors ( G-CSF) have demonstrated a significant reduction in... 
CELL LUNG-CANCER | PHASE-III TRIAL | BREAST-CANCER | 3-WEEKLY CHOP CHEMOTHERAPY | ONCOLOGY | NON-HODGKINS-LYMPHOMA | RANDOMIZED-TRIAL | COMBINATION CHEMOTHERAPY | DOSE-INTENSITY | ELDERLY-PATIENTS | G-CSF | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Drug Administration Schedule | Follow-Up Studies | Risk Assessment | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Neoplasms - mortality | Male | Treatment Outcome | Fever - chemically induced | Cause of Death | Neoplasms - drug therapy | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neutropenia - prevention & control | Primary Prevention - methods | Survival Analysis | Adult | Female | Fever - prevention & control | Neoplasms - pathology | Neutropenia - chemically induced
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17. Full Text Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update
by Gary H. Lyman and Alok A. Khorana and Nicole M. Kuderer and Agnes Y. Lee and Juan Ignacio Arcelus and Edward P. Balaban and Jeffrey M. Clarke and Christopher R. Flowers and Charles W. Francis and Leigh E. Gates and Ajay K. Kakkar and Nigel S. Key and Mark N. Levine and Howard A. Liebman and Margaret A. Tempero and Sandra L. Wong and Ann Alexis Prestrud and Anna Falanga and American Society of Clinical Oncology Clinical Practice
Journal of Clinical Oncology, ISSN 0732-183X, 06/2013, Volume 31, Issue 17, pp. 2189 - 2204
Purpose To provide recommendations about prophylaxis and treatment of venous thromboembolism (VTE) in patients with cancer. Prophylaxis in the outpatient,... 
RISK-FACTORS | ORAL RIVAROXABAN | PERIOPERATIVE THROMBOPROPHYLAXIS | ONCOLOGY | ANTICOAGULANT-THERAPY | MOLECULAR-WEIGHT HEPARIN | PULMONARY-EMBOLISM | DEEP-VEIN THROMBOSIS | RENAL IMPAIRMENT | PATIENTS RECEIVING CHEMOTHERAPY | UNFRACTIONATED HEPARIN | Venous Thromboembolism - prevention & control | Neoplasms - blood | Risk Assessment | United States | Humans | Venous Thromboembolism - therapy | Venous Thromboembolism - drug therapy | Practice Guidelines as Topic
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18. Full Text Response
by Kuderer, Nicole M and Lyman, Gary H
Journal of the National Cancer Institute, ISSN 0027-8874, 12/2010, Volume 103, Issue 24, pp. 1901 - 1903
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19. Hematopoietic growth factors in oncology
by Dale, David C and Lyman, Gary H. 1946- (Gary Herbert)
2011, 1, Cancer treatment and research, ISBN 9781441970725, Volume 157., xv, 433
This volume reviews and integrates the major advances in our understanding of the underlying molecular biology and pharmacology of hematopoietic growth factors... 
drug therapy | pharmacology | Oncology | Mechanism of action | therapeutic use | Neoplasms | Hematopoietic growth factors | Colony-Stimulating Factors | Clinical & internal medicine | Colony-Stimulating Factors - therapeutic use | Medicine & Public Health | Cancer
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20. Full Text Development and validation of a predictive model for chemotherapy- associated thrombosis
by Khorana, Aloka and Kuderer, Nicole M and Culakova, Eva and Lyman, Gary H and Francis, Charles W
Blood, ISSN 0006-4971, 05/2008, Volume 111, Issue 10, pp. 4902 - 4907
Risk of venous thromboembolism (VTE) is elevated in cancer, but individual risk factors cannot identify a sufficiently high-risk group of outpatients for... 
BREAST-CANCER | GENERAL-SURGERY | CANCER-PATIENTS | RISK-ASSESSMENT MODELS | VENOUS THROMBOEMBOLISM | FATAL PULMONARY-EMBOLISM | DEEP-VEIN THROMBOSIS | DOSE HEPARIN-PROPHYLAXIS | PLACEBO-CONTROLLED TRIAL | HEMATOLOGY | ILL MEDICAL PATIENTS | Predictive Value of Tests | Thrombosis - chemically induced | Risk Assessment | Humans | Middle Aged | Logistic Models | Male | Neoplasms - complications | Antineoplastic Agents - adverse effects | Models, Biological | Diagnosis, Computer-Assisted - methods | Female | Aged | Cohort Studies | Index Medicus | Abridged Index Medicus | Clinical Trials and Observations
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