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Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 12/2011, Volume 11, Issue 10, pp. 965 - 973
Over the last few decades, the study of nanotechnology has grown exponentially. Nanotechnology bridges science, engineering and technology; it continues to... 
Nanoparticles | Gold | Targeted drug delivery | Cancer | THERAPEUTICS | CHYMOTRYPSIN | CHEMISTRY, MEDICINAL | DRUG-DELIVERY | NANOPARTICLES INHIBIT | TUMOR | targeted drug delivery | PROLIFERATION | gold | ENHANCED PERMEABILITY | TARGETED THERAPIES | nanoparticles | COLLOIDAL GOLD | ONCOLOGY | SYSTEMS
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2016, Volume 34, Issue 12, pp. 1368 - 1375
Purpose Alisertib is an oral Aurora A kinase inhibitor with preclinical activity in neuroblastoma. Irinotecan and temozolomide have activity in patients with... 
SELECTIVE AURORA | SOLID TUMORS | ONCOLOGY | N-MYC | MLN8237 | SCHEDULES | CHILDREN | Dacarbazine - adverse effects | Tablets | Humans | Neuroblastoma - enzymology | Child, Preschool | Drug Resistance, Neoplasm | Male | Neuroblastoma - mortality | Protein Kinase Inhibitors - adverse effects | Aurora Kinase A - antagonists & inhibitors | Young Adult | Time Factors | Camptothecin - administration & dosage | Child | Camptothecin - analogs & derivatives | Protein Kinase Inhibitors - pharmacokinetics | Dacarbazine - administration & dosage | Administration, Oral | Genotype | Disease Progression | Protein Kinase Inhibitors - administration & dosage | Maximum Tolerated Dose | Phenotype | Adolescent | Pyrimidines - pharmacokinetics | United States | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Infant | Aurora Kinase A - metabolism | Glucuronosyltransferase - genetics | Dacarbazine - analogs & derivatives | Adult | Female | Neuroblastoma - pathology | Camptothecin - pharmacokinetics | Camptothecin - adverse effects | Azepines - adverse effects | Drug Administration Schedule | Pyrimidines - administration & dosage | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Treatment Outcome | Disease-Free Survival | Glucuronosyltransferase - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neuroblastoma - drug therapy | Pyrimidines - adverse effects | Azepines - pharmacokinetics | Azepines - administration & dosage | Index Medicus | Pedi18 | Pedi10 | ORIGINAL REPORTS
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20347
Background: Pancreatic cancer is the fourth leading cause of cancer related deaths in America. Monoclonal antibodies are a viable treatment option for... 
GROWTH-FACTOR-RECEPTOR | MECHANISM | MULTIDISCIPLINARY SCIENCES | CHEMISTRY | TRAFFICKING | MONOCLONAL-ANTIBODY CETUXIMAB | PARTICLE-SIZE | BIODISTRIBUTION | FUNCTIONALIZED GOLD NANOPARTICLES | NANOTECHNOLOGY | DELIVERY | Gold - chemistry | Microscopy, Electron, Transmission | Antibodies, Monoclonal - pharmacology | Humans | Metal Nanoparticles - chemistry | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Pancreatic Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Antibodies, Monoclonal, Humanized | Animals | Mice, Nude | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Mice | Cetuximab | Antibodies, Monoclonal - chemistry | Nanoconjugates - chemistry | Drugs | Care and treatment | Drug delivery systems | Biological products | Oncology, Experimental | Research | Fever | Vehicles | Epidermal growth factor | Analysis | Pancreatic cancer | Cancer cells | Monoclonal antibodies | Health aspects | Hyperthermia | Cancer | Particle size | Phosphorylation | Design parameters | Leukemia | Drug delivery | Biochemistry | Kinases | Cancer therapies | Nanoparticles | Design | Radio frequency | Computed tomography | Physiology | Mathematical models | Capillaries | Growth factors | Biomedical engineering | Gold | Medical research | Immunoglobulins | Medical imaging | Epidermal growth factor receptors | Tumor cells | Nanomaterials | Medicine | Contrast agents | Ligands | Surface area | Molecular biology | Tumors | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e57522
Background: Pancreatic cancer is one of the deadliest of all human malignancies with limited options for therapy. Here, we report the development of an... 
PHASE-III TRIAL | FACTOR-RECEPTOR | SURVIVAL | NUCLEOSIDE TRANSPORTERS | CETUXIMAB | CANCER NANOTECHNOLOGY | CLINICAL BENEFIT | DRUG-DELIVERY | MULTIDISCIPLINARY SCIENCES | COMPARING GEMCITABINE | METAL NANOPARTICLES | Immunohistochemistry | Adenocarcinoma - pathology | Designer Drugs - therapeutic use | Humans | Deoxycytidine - pharmacology | Male | Antineoplastic Agents - therapeutic use | Body Fluids - drug effects | Molecular Targeted Therapy | Nanoconjugates - therapeutic use | Pancreatic Neoplasms - drug therapy | Deoxycytidine - therapeutic use | Light | Antineoplastic Agents - pharmacology | Scattering, Radiation | Disease Models, Animal | Metal Nanoparticles - ultrastructure | Nanoconjugates - ultrastructure | Pancreatic Neoplasms - pathology | Metal Nanoparticles - therapeutic use | Treatment Outcome | Static Electricity | Adenocarcinoma - drug therapy | Animals | Body Fluids - metabolism | Mice, Nude | Cell Line, Tumor | Gold - therapeutic use | Cell Proliferation - drug effects | Mice | Deoxycytidine - analogs & derivatives | Drugs | Drug delivery systems | Care and treatment | Growth | Analysis | Oncology, Experimental | Pancreatic cancer | Nucleosides | Research | Cancer | Vehicles | Adenocarcinoma | Gold | Gemcitabine | Nucleoside transporter | Cloning | Biochemistry | Pharmacology | Thymidine | Drug delivery | Cancer therapies | Mimicry | Nanoparticles | Medicine | Physiology | In vivo methods and tests | Inhibition | Molecular biology | Pharmacokinetics | Transporter | Nanotechnology | Biomedical engineering
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2014, Volume 32, Issue 15_suppl, pp. 2627 - 2627
Journal Article
Anti-cancer agents in medicinal chemistry, 12/2011, Volume 11, Issue 10, p. 965
Journal Article
Journal of Sexual Medicine, ISSN 1743-6095, 06/2019, Volume 16, Issue 6, pp. 763 - 766
Background: Vaginal diazepam is frequently used to treat pelvic floor tension myalgia and pelvic pain despite limited knowledge of systemic absorption. Aim: To... 
Dyspareunia | Nonrelaxing Pelvic Floor Dysfunction | Chronic Pelvic Pain | Pelvic Pain | Diazepam | Pelvic Floor Dysfunction
Journal Article