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Conference Proceeding
Science, ISSN 0036-8075, 03/2015, Volume 347, Issue 6226, pp. 1117 - 1122
Chemokines and their receptors control cell migration during development, immune system responses, and in numerous diseases, including inflammation and cancer.... 
HIV-1 | CELL-DERIVED FACTOR-1-ALPHA | LYMPHOPOIESIS | SMALL-MOLECULE | CC-CHEMOKINE | MYELOPOIESIS | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | VMIP-II | SULFOTYROSINE RECOGNITION | BINDING | Proteins | Protein research | Viral proteins | Physiological aspects | Research | Structure | Chemokines | Membranes | Crystal structure | Immune systems | Binding | Receptors | Ligands | Chemokine receptors | Diseases
Journal Article
Immunity, ISSN 1074-7613, 06/2017, Volume 46, Issue 6, pp. 1005 - 1017.e5
CCR5 is the primary chemokine receptor utilized by HIV to infect leukocytes, whereas CCR5 ligands inhibit infection by blocking CCR5 engagement with HIV gp120.... 
maraviroc | V3 loop | CCL5/RANTES | G protein-coupled receptor (GPCR) | Chemokine antagonist | CCR5-gp120 interaction | viral mimicry | membrane protein structure | two-site model | HIV entry inhibitor | CCR5 Receptor Antagonists - chemistry | CCR5 Receptor Antagonists - pharmacology | Triazoles - chemistry | Cyclohexanes - pharmacology | HIV Fusion Inhibitors - chemistry | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Virus Internalization - drug effects | HIV Envelope Protein gp120 - metabolism | Spodoptera | Chemokine CCL5 - chemistry | HIV Infections - immunology | Molecular Mimicry | Receptors, CCR5 - metabolism | Sf9 Cells | HIV-1 - physiology | Cloning, Molecular | Cyclohexanes - chemistry | Chemokine CCL5 - metabolism | HIV Envelope Protein gp120 - chemistry | Models, Molecular | Triazoles - pharmacology | Animals | Protein Binding | Receptors, CCR5 - chemistry | HIV Infections - drug therapy | Protein Conformation | Hydrogen | Analysis | Pharmacy | Therapeutics | Drugstores | HIV (Viruses) | Drug approval | Homeopathy | Materia medica and therapeutics | G proteins | Membrane proteins | Similarity | Molecular structure | Infections | Leukocytes | Hydrogen bonding | Mimicry | Exploitation | Proteins | Hydrogen bonds | Design improvements | Human immunodeficiency virus--HIV | Plasticity | Chemical bonds | Modelling | Binding | CCR5 protein | Diseases | Molecular modelling | Inhibitors | Ligands | Determinants | Plastic properties | Molecular biology | Chemokines | Glycoprotein gp120 | Recognition | Cancer | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | RANTES | CCL5
Journal Article
Journal Article
Journal Article
Journal of computer-aided molecular design, ISSN 0920-654X, 01/2020, Volume 34, Issue 3, pp. 219 - 230
Small molecules binding at any of the multiple regulatory sites on the molecular surface of a protein kinase may stabilize or disrupt the corresponding... 
Proteins | Binding | Biological effects | Toxicity | Graphical representations | Kinases | ATP
Journal Article
Journal Article