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Lancet Infectious Diseases, The, ISSN 1473-3099, 2014, Volume 14, Issue 11, pp. 1083 - 1089
Summary Background Group B streptococcus is the most common cause of neonatal infections. We studied the clinical and molecular epidemiology of invasive group... 
Infectious Disease | UNITED-STATES | INFECTIOUS DISEASES | ONSET NEONATAL SEPSIS | BACTERIAL-MENINGITIS | AGALACTIAE | INFANTS | PREVENTION | CLINICAL-FEATURES | ANTIBIOTIC-PROPHYLAXIS | EPIDEMIOLOGY | YOUNGER | Guidelines as Topic | Escherichia coli Infections - prevention & control | Humans | Netherlands - epidemiology | Streptococcus agalactiae - classification | Infant | Male | Streptococcal Infections - prevention & control | Infection Control - methods | Multilocus Sequence Typing | Incidence | Streptococcus agalactiae - genetics | Streptococcus agalactiae - isolation & purification | Female | Infant, Newborn | Streptococcal Infections - microbiology | Meningitis, Bacterial - microbiology | Sepsis - epidemiology | Escherichia coli Infections - microbiology | Streptococcal Infections - epidemiology | Genotype | Escherichia coli Infections - epidemiology | Epidemiological Monitoring | Molecular Epidemiology | Meningitis, Bacterial - epidemiology | Sepsis - microbiology | Infants (Newborn) | Cross infection | Genetic aspects | Nosocomial infections | Medical research | Medical examination | Escherichia coli | Medicine, Experimental | Meningitis | Epidemiology | Blood | Disease | Laboratories | Drug resistance | Patients | Risk factors | Fever | Streptococcus infections | Studies | Disease prevention | Genotype & phenotype | Surveillance | Antibiotics | E coli | Womens health | Age
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 1, pp. 116 - 126.e11
Background Common variable immunodeficiency (CVID) is an antibody deficiency with an equal sex distribution and a high variability in clinical presentation.... 
Allergy and Immunology | patient self-reported outcomes | treatment | Common variable immunodeficiency | primary antibody deficiency | autoimmunity | enteropathy | immunoglobulin replacement | quality of life | lymphadenopathy | granulomas | INFECTIONS | PHENOTYPES | IMMUNOLOGY | DEFICIENCY | IGM | TRIAL | B-CELL | ALLERGY | HYPOGAMMAGLOBULINEMIA | INTRAVENOUS IMMUNOGLOBULIN | DISEASE | Autoimmunity | Common Variable Immunodeficiency - immunology | Common Variable Immunodeficiency - drug therapy | Humans | Child, Preschool | Lymphoproliferative Disorders - complications | Male | Lymphoproliferative Disorders - immunology | Splenomegaly - pathology | Bronchiectasis - pathology | Common Variable Immunodeficiency - mortality | Pneumonia - mortality | Pneumonia - immunology | Adult | Female | Retrospective Studies | Child | Europe | Delayed Diagnosis | Common Variable Immunodeficiency - complications | Lymphoproliferative Disorders - mortality | Pneumonia - drug therapy | Immunoglobulins, Intravenous - therapeutic use | Adolescent | Age of Onset | Survival Analysis | Pneumonia - complications | Lymphoproliferative Disorders - drug therapy | Immunological deficiency syndromes | Care and treatment | Health aspects | Respiratory tract diseases | Studies | Pneumonia | Meningitis | Lymphomas | Multivariate analysis | Patients | Age | Data bases
Journal Article
by Tuijnenburg, Paul and Lango Allen, Hana and Burns, Siobhan O and Burns, Siobhan and Greene, Daniel and Jansen, Machiel H and Staples, Emily and Stephens, Jonathan and Carss, Keren J and Carss, Keren and Biasci, Daniele and Baxendale, Helen and Thomas, Moira and Chandra, Anita and Kiani-Alikhan, Sorena and Longhurst, Hilary and Longhurst, Hilary J and Seneviratne, Suranjith and Seneviratne, Suranjith L and Oksenhendler, Eric and Simeoni, Ilenia and de Bree, Godelieve J and Tool, Anton T.J and van Leeuwen, Ester M.M and Ebberink, Eduard H.T.M and Meijer, Alexander B and Tuna, Salih and Whitehorn, Deborah and Brown, Matthew and Turro, Ernest and Thrasher, Adrian and Thrasher, Adrian J and Smith, Kenneth G.C and Thaventhiran, James E and Thaventhiran, James and Kuijpers, Taco W and Kuijpers, Taco and Adhya, Zoe and Alachkar, Hana and Anantharachagan, Ariharan and Antrobus, Richard and Arumugakani, Gururaj and Bacchelli, Chiara and Bethune, Claire and Bibi, Shahnaz and Boardman, Barbara and Booth, Claire and Browning, Michael and Brownlie, Mary and Clifford, Hayley and Cooper, Nichola and Davies, Sophie and Dempster, John and Devlin, Lisa and Doffinger, Rainer and Drewe, Elizabeth and Edgar, David and Egner, William and El-Shanawany, Tariq and Gaspar, Bobby and Ghurye, Rohit and Gilmour, Kimberley and Goddard, Sarah and Gordins, Pavel and Grigoriadou, Sofia and Hackett, Scott and Hague, Rosie and Harper, Lorraine and Hayman, Grant and Herwadkar, Archana and Hughes, Stephen and Huissoon, Aarnoud and Jolles, Stephen and Jones, Julie and Kelleher, Peter and Klein, Nigel and Kumararatne, Dinakantha and Laffan, James and Lear, Sara and Lorenzo, Lorena and Maimaris, Jesmeen and Manson, Ania and McDermott, Elizabeth and Millar, Hazel and Mistry, Anoop and Morrisson, Valerie and Murng, Sai and Nasir, Iman and Nejentsev, Sergey and Noorani, Sadia and Ponsford, Mark and Qasim, Waseem and Quinn, Ellen and Quinti, Isabella and Richter, Alex and Samarghitean, Crina and Sargur, Ravishankar and Savic, Sinisa and Sewall, Carrock and Shackley, Fiona and ... and NIHR BioResource-Rare Dis and NIHR BioResource–Rare Diseases Consortium
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 10/2018, Volume 142, Issue 4, pp. 1285 - 1296
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 4, pp. e5234 - e5234
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2012, Volume 69, Issue 1, pp. 7 - 15
Chronic granulomatous disease (CGD) is an uncommon congenital immunodeficiency seen approximately in 1 of 250,000 individuals. It is caused by a profound... 
Biochemistry, general | Granuloma | Tregs | Tryptophan | Inflammation | Biomedicine general | Cell Biology | Life Sciences | Infection | Life Sciences, general | IDO | NADPH oxidase | IL-17 | Kynurenine | ASPERGILLUS-FUMIGATUS | RESPIRATORY BURST | CHRONIC GRANULOMATOUS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDOLEAMINE 2,3-DIOXYGENASE | TRYPTOPHAN CATABOLISM | CELL BIOLOGY | IMMUNE-RESPONSES | REGULATORY T-CELLS | HOST-DEFENSE | INDEPENDENT ACTIVATION | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | T-Lymphocytes, Regulatory - metabolism | Humans | Granulomatous Disease, Chronic - genetics | Interleukin-17 - immunology | NADPH Oxidases - immunology | Male | Phagocytes - pathology | Respiratory Burst - immunology | Granulomatous Disease, Chronic - immunology | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Superoxides - immunology | NF-E2-Related Factor 2 - immunology | T-Lymphocytes, Regulatory - immunology | NADPH Oxidases - deficiency | Inflammation - metabolism | Superoxides - metabolism | Female | Models, Animal | Kynurenine - metabolism | Transforming Growth Factor beta - immunology | Phagocytosis - physiology | Inflammation - immunology | NF-E2-Related Factor 2 - deficiency | Phagocytes - immunology | Interleukin-17 - metabolism | Animals | Phagocyte Bactericidal Dysfunction - immunology | Mice | Kynurenine - immunology | Transforming Growth Factor beta - metabolism | Oxidases | Genetic disorders | Hydroxides | Hydrogen peroxide | Immunodeficiency | Respiratory agents | Superoxide | Transplantation | Macrophages | Hematopoietic stem cells | Fungi | Bacteria | Health aspects | Infections | Oxidation | Inflammatory diseases | Chronic granulomatous disease | Myeloid cells | Free radicals | Hypochlorous acid | Recurrent infection | Leukocytes (eosinophilic) | stem cell transplantation | Oxygen consumption | Leukocytes (neutrophilic) | Phagocytes | Monocytes | Respiratory burst | Phagocytosis | Multi-Author Review
Journal Article
PLoS genetics, ISSN 1553-7390, 2009, Volume 5, Issue 1, p. e1000319
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 140, Issue 1, pp. 273 - 277.e10
Arp2/3 gene deletions result in embryonic lethality in the mouse.2 The genetic defects in the regulatory proteins for cytoskeletal rearrangements cause... 
Allergy and Immunology | ALLERGY | IMMUNOLOGY | WASP | Severity of Illness Index | Disease Susceptibility | Actin-Related Protein 2-3 Complex - deficiency | Severe Combined Immunodeficiency - diagnosis | Humans | Hypersensitivity - complications | Severe Combined Immunodeficiency - etiology | Inflammation - complications | Inflammation - metabolism | Phenotype | Animals | Hypersensitivity - metabolism | Biopsy | DNA Mutational Analysis | Biomarkers | Inflammation - genetics | Hypersensitivity - genetics | Severe Combined Immunodeficiency - metabolism | Mice | Skin - pathology | Disease Models, Animal | Skin - immunology | Allergy | Medical colleges | Medical research | Immunodeficiency | Medicine, Experimental | Children | Allergic reaction | Diseases | Blood proteins | Cdc42 protein | Salmonella | Nucleation | Motility | Guanosine | Disorders | Erythrocytes | Immunoglobulin E | Lymphocytes T | Lethality | Infections | In vitro testing | Confocal | Immunoglobulin A | Blood | Bleeding | Defects | Proteins | Signal transduction | Anaphylaxis | Immunology | Blood platelets | Lymphocytes | Actin | Age | Wiskott-Aldrich syndrome | Antigens | Blood cells | Hypersensitivity | Neutrophils | Polymerization | Leukocytes (neutrophilic) | Rac2 protein | Chemotaxis | Embryos | Adhesion | White blood cells | Leukocytosis | Proteomics | Cytoskeleton | Transduction | Mutation | Platelets | Regulatory proteins
Journal Article
by Farmery, James H. R and Smith, Mike L and Huissoon, Aarnoud and Furnell, Abigail and Mead, Adam and Levine, Adam P and Manzur, Adnan and Thrasher, Adrian and Greenhalgh, Alan and Parker, Alasdair and Sanchis-Juan, Alba and Richter, Alex and Gardham, Alice and Lawrie, Allan and Sohal, Aman and Creaser-Myers, Amanda and Frary, Amy and Greinacher, Andreas and Themistocleous, Andreas and Peacock, Andrew J and Marshall, Andrew and Mumford, Andrew and Rice, Andrew and Webster, Andrew and Brady, Angie and Koziell, Ania and Manson, Ania and Chandra, Anita and Hensiek, Anke and Veld, Anna Huis In'T and Maw, Anna and Kelly, Anne M and Moore, Anthony and Vonk Noordegraaf, Anton and Attwood, Antony and Herwadkar, Archana and Ghofrani, Ardi and Houweling, Arjan C and Girerd, Barbara and Furie, Bruce and Treacy, Carmen M and Millar, Carolyn M and Sewell, Carrock and Roughley, Catherine and Titterton, Catherine and Williamson, Catherine and Hadinnapola, Charaka and Deshpande, Charu and Toh, Cheng-Hock and Bacchelli, Chiara and Patch, Chris and Geet, Chris Van and Babbs, Christian and Bryson, Christine and Penkett, Christopher J and Rhodes, Christopher J and Watt, Christopher and Bethune, Claire and Booth, Claire and Lentaigne, Claire and McJannet, Coleen and Church, Colin and French, Courtney and Samarghitean, Crina and Halmagyi, Csaba and Gale, Daniel and Greene, Daniel and Hart, Daniel and Allsup, David and Bennett, David and Edgar, David and Kiely, David G and Gosal, David and Perry, David J and Keeling, David and Montani, David and Shipley, Debbie and Whitehorn, Deborah and Fletcher, Debra and Krishnakumar, Deepa and Grozeva, Detelina and Kumararatne, Dinakantha and Thompson, Dorothy and Josifova, Dragana and Maher, Eamonn and Wong, Edwin K. S and Murphy, Elaine and Dewhurst, Eleanor and Louka, Eleni and Rosser, Elisabeth and Chalmers, Elizabeth and Colby, Elizabeth and Drewe, Elizabeth and McDermott, Elizabeth and Thomas, Ellen and Staples, Emily and Clement, Emma and Matthews, Emma and Wakeling, Emma and Oksenhendler, Eric and ... and NIHR BioResource-Rare Dis and NIHR BioResource - Rare Diseases
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1300 - 17
Telomere length is a risk factor in disease and the dynamics of telomere length are crucial to our understanding of cell replication and vitality. The... 
MULTIDISCIPLINARY SCIENCES | DISEASE | Telomeres | Ploidy | Computer applications | Data processing | Genomes | Chromosomes | Telomerase | Genotypes | Cancer
Journal Article