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1. Full Text Identification of stem cells in small intestine and colon by marker gene Lgr5
by Barker, Nick and Van Es, Johan H and Kuipers, Jeroen and Kujala, Pekka and Van Den Born, Maaike and Cozijnsen, Miranda and Haegebarth, Anea and Korving, Jeroen and Begthel, Harry and Peters, Peter J and Clevers, Hans
Nature, ISSN 0028-0836, 10/2007, Volume 449, Issue 7165, pp. 1003 - 1007
The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals. It is currently believed that four to six crypt stem cells reside at the... 
GPR49 | OVEREXPRESSION | RENEWAL | PROTEIN-COUPLED RECEPTOR | MULTIDISCIPLINARY SCIENCES | MOUSE SMALL-INTESTINE | EPITHELIAL PROGENITORS | EXPRESSION | CANCER | MUSASHI-1 | ADULT-MOUSE | Colon - cytology | Paneth Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Gene Expression Profiling | Stem Cells - metabolism | Animals | Intestine, Small - cytology | Alleles | Biomarkers | Cell Line, Tumor | Mice | Receptors, G-Protein-Coupled - genetics | Genes, Reporter | Medical examination | Intestine, Small | Stem cells | Genetic aspects | Colon (Anatomy) | Identification and classification | Health aspects | Genetic markers | Biomedical research | Cellular biology | Rodents | Cancer
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2. Full Text A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen
by Impagliazzo, Antonietta and Milder, Fin and Kuipers, Harmjan and Wagner, Michelle V and Zhu, Xueyong and Hoffman, Ryan M. B and van Meersbergen, Ruud and Huizingh, Jeroen and Wanningen, Patrick and Verspuij, Johan and de Man, Martijn and Ding, Zhaoqing and Apetri, Aian and Kükrer, Başak and Sneekes-Vriese, Eveline and Tomkiewicz, Danuta and Laursen, Nick S and Lee, Peter S and Zakrzewska, Anna and Dekking, Liesbeth and Tolboom, Jeroen and Tettero, Lisanne and van Meerten, Sander and Yu, Wenli and Koudstaal, Wouter and Goudsmit, Jaap and Ward, Anew B and Meijberg, Wim and Wilson, Ian A and Radošević, Katarina
Science, ISSN 0036-8075, 2015, Volume 349, Issue 6254, pp. 1301 - 1306
The identification of human broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem revitalized hopes of developing a universal influenza... 
CELLS | DESIGN | NEUTRALIZING ANTIBODIES | EPITOPE | STALK DOMAIN | A VIRUSES | MULTIDISCIPLINARY SCIENCES | VACCINE | THERAPEUTIC ANTIBODIES | VIRUS HEMAGGLUTININ | GLOBULAR HEAD | Influenza A Virus, H1N1 Subtype - immunology | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Protein Structure, Secondary | Humans | Protein Multimerization | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Antibodies, Neutralizing - immunology | Animals | Influenza Vaccines - immunology | Influenza A Virus, H5N1 Subtype - immunology | Antibodies, Viral - immunology | Mice | Influenza, Human - prevention & control | Lectins | Antigens | Influenza | Viral antibodies | Influenza viruses | Antibodies | Health aspects | Proteins | Vaccines | Mutation | Binding | Design engineering | Primates | Viruses
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3. Full Text Molecular signatures of the evolving immune response in mice following a Bordetella pertussis infection
by Raeven, René H. M and Brummelman, Jolanda and Pennings, Jeroen L. A and Nijst, Olaf E. M and Kuipers, Betsy and Blok, Laura E. R and Helm, Kina and Van Riet, Elly and Jiskoot, Wim and Van Els, Cecile A. C. M and Han, Wanda G. H and Kersten, Gideon F. A and Metz, Bernard
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e104548
Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies. Since natural infections induce a... 
OUTER-MEMBRANE VESICLES | RESPIRATORY-INFECTION | MURINE MODEL | INNATE RESISTANCE | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | CELL-MEDIATED-IMMUNITY | WHOLE-CELL | T-CELLS | NEUTROPHIL RECRUITMENT | CUTTING EDGE | Th1 Cells - pathology | Lung - microbiology | Bordetella Infections - immunology | Spleen - immunology | Bordetella Infections - microbiology | Complement Activation | Immunoglobulin A - biosynthesis | Bordetella Infections - genetics | Bordetella pertussis - immunology | Th1 Cells - immunology | Spleen - microbiology | Host-Pathogen Interactions - immunology | alpha-Defensins - genetics | Antibodies, Bacterial - biosynthesis | Female | Spleen - pathology | Transcription Factors - immunology | Cytokines - genetics | Bordetella Infections - pathology | Cytokines - immunology | Th17 Cells - pathology | Adaptive Immunity | Lung - pathology | Gene Expression Regulation - immunology | Transcription Factors - genetics | Immunity, Innate | Receptors, Cell Surface - immunology | Th1 Cells - microbiology | Animals | alpha-Defensins - immunology | Th17 Cells - immunology | Immunologic Memory | Mice | Mice, Inbred BALB C | Lung - immunology | Th17 Cells - microbiology | Receptors, Cell Surface - genetics | Infection | Analysis | Vaccines | Bordetella pertussis | T cells | Immunoglobulin A | Health aspects | Flow cytometry | Transcription factors | Genomics | Vaccination | Immune clearance | Helper cells | Lymphocytes T | Infections | Immunity | Pertussis | Immunology | Rodents | Transcription activation | Animal tissues | Evolution | Bacteria | Signatures | Drug dosages | Public health | Immune system | Spleen | Immunological memory | Memory cells | Immune response | Cytokines | Principal components analysis | Gene expression | Disease control | Whooping cough | Computer memory | Cytometry | DNA microarrays | Infectious diseases | Lymphocytes B | Lungs | Kinetics | Immunoassays
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4. Full Text Mini-HA is superior to full length hemagglutinin immunization in inducing stem-specific antibodies and protection against group 1 influenza virus challenges in mice
by Van Der Lubbe, Joan E.M and Verspuij, Johan W.A and Huizingh, Jeroen and Schmit-Tillemans, Sonja P.R and Tolboom, Jeroen T.B.M and Dekking, Liesbeth E.H.A and Kwaks, Ted and Brandenburg, Börries and Meijberg, Wim and Zahn, Roland C and Roozendaal, Ramon and Kuipers, Harmjan
Frontiers in Immunology, ISSN 1664-3224, 10/2018, Volume 9
Seasonal influenza vaccines are updated almost annually to match the antigenic drift in influenza hemagglutinin (HA) surface glycoprotein. A new HA stem-based... 
Antibodies | Mouse influenza challenge models | Universal influenza vaccine | Influenza | Hemagglutinin stem immunogen | influenza | ANTIGENIC STRUCTURE | PREVENTION | INDUCTION | IMMUNOLOGY | NEUTRALIZING EPITOPE | hemagglutinin stem immunogen | DEPENDENT CELLULAR CYTOTOXICITY | H5N1 | universal influenza vaccine | ADVISORY-COMMITTEE | SEASONAL INFLUENZA | mouse influenza challenge models | antibodies | INFECTION | VACCINES RECOMMENDATIONS | Viral antibodies | Prevention | Immunization | Usage | Rats as laboratory animals | Research
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5. Full Text Experimental investigation of non-Newtonian droplet collisions: the role of extensional viscosity
by Finotello, Giulia and De, Shauvik and Vrouwenvelder, Jeroen C. R and Padding, Johan T and Buist, Kay A and Jongsma, Alfred and Innings, Fredrik and Kuipers, J A. M
Experiments in Fluids, ISSN 0723-4864, 7/2018, Volume 59, Issue 7, pp. 1 - 16
We investigate the collision behaviour of a shear thinning non-Newtonian fluid xanthan, by binary droplet collision experiments. Droplet collisions of... 
Engineering | Engineering Fluid Dynamics | Fluid- and Aerodynamics | Engineering Thermodynamics, Heat and Mass Transfer | VACUUM | MECHANICS | XANTHAN GUM | COALESCENCE | RHEOLOGICAL BEHAVIOR | SEPARATION | MODEL | NUMERICAL SIMULATIONS | BINARY COLLISIONS | ENGINEERING, MECHANICAL | Glycerin | Glycerol | Analysis | Milk
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6. Full Text Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis
by Nijmeijer, Rian M and van Santvoort, Hjalmar C and Zhernakova, Alexana and Teller, Steffen and Scheiber, Jonas A and de Kovel, Carolien G and Besselink, Marc G. H and Visser, Jeroen T. J and Lutgendorff, Femke and Bollen, Thomas L and Boermeester, Marja A and Rijkers, Ger T and Weiss, Frank U and Mayerle, Julia and Lerch, Markus M and Gooszen, Hein G and Akkermans, Louis M. A and Wijmenga, Cisca and van Ramshorst, B and Weusten, B. L and Timmer, R and van Erpecum, K. J and Cirkel, G. A and Zeguers, V and Roeterdink, A and Rijnhart, H. G and Schwartz, M. P and van Leeuwen, M. S and Ridwan, B. U and Witteman, B. J and Kruyt, P. M and van Laarhoven, C. J and xler, T. A and Nieuwenhuijs, V. B and Ploeg, R. J and Hofker, H. S and Kruijt Spanjer, M. R and Buitenhuis, H. T and van Vliet, S. U and Ramcharan, S and Nooteboom, A and van Goor, H and Jansen, J. B and Bongaerts, G. T and Buscher, H. C and Brink, M. A and Mundt, M and Frankhuisen, R and Consten, E. C and van Ruler, O and Gouma, D. J and Bruno, M. J and Dejong, C. H and Rutten, J. P and Tan, A. C and Rosman, C and Ootes, L and Houben, B and Schaapherder, A. F and Haasnoot, A and van Eijck, C. H and van der Wal, J. B. C and van 't Hof, G and Kuipers, E. J and Wahab, P and Spillenaar Bilgen, E. J and van Embden, P and Kubben, F. J and van der Harst, E and Lange, J. F and Wijffels, N. A and van Walraven, L. A and Dutch Pancreatitis Study Grp and Dutch Pancreatitis Study Group and on behalf of the Dutch Pancreatitis Study Group
PLoS ONE, ISSN 1932-6203, 2013, Volume 8, Issue 12, p. e85870
Impairment of the mucosal barrier plays an important role in the pathophysiology of acute pancreatitis. The myosin IXB (MYO9B) gene and the two tight-junction... 
DIABETIC-PATIENTS | UNITED-STATES | BARRIER DYSFUNCTION | INCREASED INTESTINAL PERMEABILITY | CROHNS-DISEASE | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | MY09B GENE | ORGAN FAILURE | EXOCRINE PANCREAS | CELIAC-DISEASE | Acute Disease | Membrane Proteins - genetics | Humans | Middle Aged | Male | Myosins - genetics | Carrier Proteins - genetics | Pancreatitis - genetics | Netherlands | Cell Cycle Proteins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Germany | Cohort Studies | Medical research | Genes | Pancreatitis | Development and progression | Research | Permeability | Muscle proteins | Analysis | Myosin | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Ulcerative colitis | Haplotypes | Inflammatory bowel diseases | Disease | Mucosa | Association analysis | Single-nucleotide polymorphism | Small intestine | Confidence intervals | Immunology | Etiology | Intestine | Rodents | Surgery | Genetics | Bioinformatics | Internal medicine | Genetic diversity | Patients | Inflammatory bowel disease | Medicine | Studies | Genetic variance | Celiac disease | Hospitals | Diabetes | Autoimmune diseases
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7. Full Text Scanning EM of non-heavy metal stained biosamples: Large-field of view, high contrast and highly efficient immunolabeling
by Kuipers, Jeroen and de Boer, Pascal and Giepmans, Ben N.G
Experimental Cell Research, ISSN 0014-4827, 10/2015, Volume 337, Issue 2, pp. 202 - 207
Scanning electron microscopy (SEM) is increasing its application in life sciences for electron density measurements of ultrathin sections. These are... 
Scanning EM | Nanotomy | Scanning transmission EM | Quantum dots | Virtual EM | Contrasting | Transmission EM | Immuno-EM | CELLS | ENERGY | VOLUME ELECTRON-MICROSCOPY | ORGANELLES | RESOLUTION | TISSUE | CELL BIOLOGY | CORRELATED LIGHT | ONCOLOGY | Gold - chemistry | Staining and Labeling - methods | Microscopy, Electron, Scanning | Metals - chemistry | Quantum Dots | Models, Biological | Humans | Nanotechnology | Cells | INSPECTION | TRANSMISSION ELECTRON MICROSCOPY | HEAVY METALS | LABELLING | BIOMEDICAL RADIOGRAPHY | ELECTRONS | SAMPLE PREPARATION | INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY | 60 APPLIED LIFE SCIENCES | ELECTRON DETECTION | ELECTRON DENSITY | SCANNING ELECTRON MICROSCOPY | LEAD
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8. Chapters in game theory
: in honor of Stef Tijs
by Tijs, Stef and Borm, Peter and Peters, Hans (Hans J. M.) and SpringerLink (Online service)
2002, Theory and decision library. Series C, Game theory, mathematical programming, and operations research, ISBN 1402070632, Volume 31, xvii, 314
Chapters in Game Theory has been written on the occasion of the 65th birthday of Stef Tijs, who can be regarded as the godfather of game theory in the... 
Game theory | Microeconomics | Operations research | Economic theory | Operations Research/Decision Theory | Economic Theory/Quantitative Economics/Mathematical Methods
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9. Full Text Brilliant camouflage: photonic crystals in the diamond weevil, Entimus imperialis
by Bodo D. Wilts and Kristel Michielsen and Jeroen Kuipers and Hans De Raedt and Doekele G. Stavenga
Proceedings: Biological Sciences, ISSN 0962-8452, 7/2012, Volume 279, Issue 1738, pp. 2524 - 2530
The neotropical diamond weevil, Entimus impenalis, is marked by rows of brilliant spots on the overall black elytra. The spots are concave pits with intricate... 
Animal camouflage | Beetles | Colors | Crystals | Imperialism | Optical reflection | Spectral reflectance | Butterflies | Photonics | Weevils | Photonic bandgap materials | Structural colour | Scatterometry | Diffuse reflection | Communication | photonic bandgap materials | diffuse reflection | scatterometry | BEETLES | BIRD | LIGHT | STRUCTURAL COLORS | BUTTERFLY WING SCALES | EVOLUTIONARY BIOLOGY | DISRUPTIVE COLORATION | POLARIZED IRIDESCENCE | BIOLOGY | ECOLOGY | INTERFERENCE | communication | COLEOPTERA | structural colour | Microscopy, Electron, Transmission | Wings, Animal - ultrastructure | Coleoptera - chemistry | Crystallization | Photons | Pigmentation | Coleoptera - ultrastructure | Behavior, Animal | Animals | Computer Simulation | Refractometry | Wings, Animal - chemistry | Coleoptera - physiology | 201 | 1001
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10. Full Text Explaining the survival of public organizations: Applying density dependence theory to a population of US federal agencies
by van Witteloostuijn, Arjen and Boin, Arjen and Kofman, Celesta and Kuilman, Jeroen and Kuipers, Sanneke
Public Administration, ISSN 0033-3298, 12/2018, Volume 96, Issue 4, pp. 633 - 650
Why do some public organizations survive for many decades, whereas others are terminated within a few years? This question of organizational survival has long... 
MORTALITY | MATTER | DESIGN | ASSOCIATIONS | POLITICAL SCIENCE | ADAPTATION | POLITICS | PUBLIC ADMINISTRATION | ECOLOGY | DEATH | CHALLENGES | AUTONOMY | Analysis | Administrative agencies | Public sector | Competition | Ecology | Longevity | Intellectuals | Public administration
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11. Full Text Large-Scale Electron Microscopy Maps of Patient Skin and Mucosa Provide Insight into Pathogenesis of Blistering Diseases
by Sokol, Ena and Kramer, Duco and Diercks, Gilles F.H and Kuipers, Jeroen and Jonkman, Marcel F and Pas, Hendri H and Giepmans, Ben N.G
Journal of Investigative Dermatology, ISSN 0022-202X, 07/2015, Volume 135, Issue 7, pp. 1763 - 1770
Large-scale electron microscopy (“nanotomy”) allows straight forward ultrastructural examination of tissue, cells, organelles, and macromolecules in a single... 
DESMOSOMES | BULLOUS IMPETIGO | ACANTHOLYSIS | ULTRASTRUCTURE | HYPOTHESIS | KERATINOCYTES | VULGARIS | PEMPHIGUS FOLIACEUS | DESMOGLEIN 1 | BINDING | DERMATOLOGY | Immunohistochemistry | Desmosomes - ultrastructure | Humans | Pemphigus - physiopathology | Acantholysis - pathology | Reference Values | Skin Diseases, Vesiculobullous - pathology | Skin Diseases, Vesiculobullous - physiopathology | Nanostructures | Case-Control Studies | Desmosomes - pathology | Microscopy, Electron - methods | Pemphigus - pathology | Sensitivity and Specificity | Skin - ultrastructure | Mouth Mucosa - ultrastructure | Blister - pathology | Biopsy, Needle | Mouth Mucosa - pathology | Skin - pathology
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12. Full Text Human adipose tissue-derived stromal cells act as functional pericytes in mice and suppress high-glucose-induced proinflammatory activation of bovine retinal endothelial cells
by Hajmousa, Ghazaleh and Przybyt, Ewa and Pfister, Frederick and Paredes-Juarez, Genaro A and Moganti, Kondaiah and Busch, Stephanie and Kuipers, Jeroen and Klaassen, Ingeborg and van Luyn, Marja J. A and Krenning, Guido and Hammes, Hans-Peter and Harmsen, Martin C
Diabetologia, ISSN 0012-186X, 11/2018, Volume 61, Issue 11, pp. 2371 - 2385
The immunomodulatory capacity of adipose tissue-derived stromal cells (ASCs) is relevant for next-generation cell therapies that aim to reverse tissue... 
Diabetic retinopathy | Oxidative stress | Adipose tissue-derived stromal cells | High glucose | CYCLOOXYGENASE-2 | ANGIOGENESIS | RAT | MODEL | MESENCHYMAL STEM-CELLS | IN-VITRO | PROLIFERATIVE DIABETIC-RETINOPATHY | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | EXPRESSION | PROSTAGLANDIN E-2 | Pericytes - drug effects | Humans | Pericytes - cytology | Adipose Tissue - cytology | Male | Monocytes - metabolism | Retina - cytology | Cattle | Female | Wound Healing - drug effects | Cell Survival - drug effects | Enzyme-Linked Immunosorbent Assay | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | E-Selectin - metabolism | Glucose - pharmacology | Cell Adhesion - drug effects | Diabetic Retinopathy - metabolism | Monocytes - drug effects | Intercellular Adhesion Molecule-1 - metabolism | Animals | Signal Transduction - drug effects | Mice | Oxidative Stress - drug effects | Vascular Cell Adhesion Molecule-1 - metabolism | Stromal Cells - cytology | Endothelial Cells - drug effects | Adipose tissues | Analysis | Glucose | Ophthalmology | Cells | Dextrose | Endothelium | NF-κB protein | Retinopathy | Adipose tissue | Intercellular adhesion molecule 1 | Immunoregulation | Immunomodulation | Diabetes mellitus | Paracrine signalling | Retina | Inflammation | Endothelial cells | Angiogenesis | Monocytes | Stromal cells | Pericytes | Diabetes | Capillaries
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