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Nature Medicine, ISSN 1078-8956, 11/2016, Volume 22, Issue 11, p. 1314
Journal Article
RNA (New York, N.Y.), ISSN 1355-8382, 04/2015, Volume 21, Issue 4, pp. 640 - 641
In the last 25 years, research on mRNA 3'end processing has been an exciting growing field. Studying the polyadenylation complex in its function, biochemistry,... 
RNA Processing, Post-Transcriptional | RNA, Messenger - metabolism | Index Medicus
Journal Article
by Jones, David T. W and Hutter, Barbara and Jäger, Natalie and Korshunov, Aney and Kool, Marcel and Warnatz, Hans-Jörg and Zichner, Thomas and Lambert, Sally R and Ryzhova, Marina and Quang, Dong Anh Khuong and Fontebasso, Adam M and Stütz, Aian M and Hutter, Sonja and Zuckermann, Marc and Sturm, Dominik and Gronych, Jan and Lasitschka, Bärbel and Schmidt, Sabine and Seker-Cin, Huriye and Witt, Henik and Sultan, Marc and Ralser, Meryem and Northcott, Paul A and Hovestadt, Volker and Bender, Sebastian and Pfaff, Elke and Stark, Sebastian and Faury, Damien and Schwartzentruber, Jeremy and Majewski, Jacek and Weber, Ursula D and Zapatka, Marc and Raeder, Benjamin and Schlesner, Matthias and Worth, Catherine L and Bartholomae, Cynthia C and von Kalle, Christof and Imbusch, Charles D and Radomski, Sylwester and Lawerenz, Chris and van Sluis, Peter and Koster, Jan and Volckmann, Richard and Versteeg, Rogier and Lehrach, Hans and Monoranu, Camelia and Winkler, Beate and Unterberg, Aneas and Herold-Mende, Christel and Milde, Till and Kulozik, Aneas E and Ebinger, Martin and Schuhmann, Martin U and Cho, Yoon-Jae and Pomeroy, Scott L and von Deimling, Aneas and Witt, Olaf and Taylor, Michael D and Wolf, Stephan and Karajannis, Matthias A and Eberhart, Charles G and Scheurlen, Wolfram and Hasselblatt, Martin and Ligon, Keith L and Kieran, Mark W and Korbel, Jan O and Yaspo, Marie-Laure and Brors, Benedikt and Felsberg, Jörg and Reifenberger, Guido and Collins, V. Peter and Jabado, Nada and Eils, Roland and Lichter, Peter and Pfister, Stefan M and Int Canc Genome Consortium and International Cancer Genome Consortium PedBrain Tumor Project and the International Cancer Genome Consortium PedBrain Tumor Project
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 8, pp. 927 - 932
Journal Article
by Sturm, Dominik and Witt, Hendrik and Witt, Olaf and Hovestadt, Volker and Khuong-Quang, Dong-Anh and Jones, David T.W and Konermann, Carolin and Pfaff, Elke and Tönjes, Martje and Sill, Martin and Bender, Sebastian and Kool, Marcel and Zapatka, Marc and Becker, Natalia and Zucknick, Manuela and Hielscher, Thomas and Liu, Xiao-Yang and Fontebasso, Adam M and Ryzhova, Marina and Albrecht, Steffen and Jacob, Karine and Wolter, Marietta and Ebinger, Martin and Schuhmann, Martin U and van Meter, Timothy and Frühwald, Michael C and Hauch, Holger and Pekrun, Arnulf and Radlwimmer, Bernhard and Niehues, Tim and von Komorowski, Gregor and Dürken, Matthias and Kulozik, Andreas E and Madden, Jenny and Donson, Andrew and Foreman, Nicholas K and Drissi, Rachid and Fouladi, Maryam and Scheurlen, Wolfram and von Deimling, Andreas and Monoranu, Camelia and Roggendorf, Wolfgang and Herold-Mende, Christel and Unterberg, Andreas and Kramm, Christof M and Felsberg, Jörg and Hartmann, Christian and Wiestler, Benedikt and Wick, Wolfgang and Milde, Till and Lindroth, Anders M and Schwartzentruber, Jeremy and Faury, Damien and Fleming, Adam and Zakrzewska, Magdalena and Liberski, Pawel P and Zakrzewski, Krzysztof and Hauser, Peter and Garami, Miklos and Klekner, Almos and Bognar, Laszlo and Morrissy, Sorana and Cavalli, Florence and Taylor, Michael D and van Sluis, Peter and Koster, Jan and Versteeg, Rogier and Volckmann, Richard and Mikkelsen, Tom and Aldape, Kenneth and Reifenberger, Guido and Collins, V. Peter and Majewski, Jacek and Korshunov, Andrey and Lichter, Peter and Plass, Christoph and Jabado, Nada and Pfister, Stefan M
Cancer Cell, ISSN 1535-6108, 10/2012, Volume 22, Issue 4, pp. 425 - 437
Journal Article
by Kool, Marcel and Jones, David T.W and Jäger, Natalie and Northcott, Paul A and Pugh, Trevor J and Hovestadt, Volker and Piro, Rosario M and Esparza, L. Adriana and Markant, Shirley L and Remke, Marc and Milde, Till and Bourdeaut, Franck and Ryzhova, Marina and Sturm, Dominik and Pfaff, Elke and Stark, Sebastian and Hutter, Sonja and Şeker-Cin, Huriye and Johann, Pascal and Bender, Sebastian and Schmidt, Christin and Schmidt, Sabine and Rausch, Tobias and Shih, David and Reimand, Jüri and Sieber, Laura and Wittmann, Andrea and Linke, Linda and Witt, Olaf and Witt, Hendrik and Weber, Ursula D and Zapatka, Marc and König, Rainer and Beroukhim, Rameen and Bergthold, Guillaume and van Sluis, Peter and Volckmann, Richard and Koster, Jan and Versteeg, Rogier and Wolf, Stephan and Lawerenz, Chris and Bartholomae, Cynthia C and von Kalle, Christof and Unterberg, Andreas and Herold-Mende, Christel and Hofer, Silvia and Kulozik, Andreas E and von Deimling, Andreas and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Hasselblatt, Martin and Crawford, John R and Grant, Gerald A and Jabado, Nada and Perry, Arie and Cowdrey, Cynthia and Croul, Sydney and Zadeh, Gelareh and Korbel, Jan O and Doz, Francois and Delattre, Olivier and Bader, Gary D and McCabe, Martin G and Collins, V. Peter and Kieran, Mark W and Cho, Yoon-Jae and Pomeroy, Scott L and Brors, Benedikt and Taylor, Michael D and Schüller, Ulrich and Korshunov, Andrey and Eils, Roland and Wechsler-Reya, Robert J and Lichter, Peter and Pfister, Stefan M and ICGC PedBrain Tumor Project
Cancer Cell, ISSN 1535-6108, 03/2014, Volume 25, Issue 3, pp. 393 - 405
Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven medulloblastoma (SHH-MB). Clinical response is highly variable. To... 
NERVOUS-SYSTEM | TERT PROMOTER MUTATIONS | ONCOLOGY | GROWTH | HEDGEHOG PATHWAY INHIBITOR | ITRACONAZOLE | PEDIATRIC MEDULLOBLASTOMA | CANCER | TUMORS | MOUSE MODELS | ADULT | CELL BIOLOGY | Neoplasm Transplantation | Oncogene Proteins - genetics | Humans | Zinc Finger Protein Gli2 | Child, Preschool | Molecular Sequence Data | Infant | Male | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - therapeutic use | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Young Adult | Telomerase - genetics | Hedgehog Proteins - genetics | Base Sequence | Smoothened Receptor | Adult | Female | N-Myc Proto-Oncogene Protein | Patched Receptors | Medulloblastoma - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Child | Pyridines - therapeutic use | Cerebellar Neoplasms - drug therapy | Repressor Proteins - genetics | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Cerebellar Neoplasms - genetics | Mice, SCID | Phosphatidylinositol 3-Kinases - genetics | DEAD-box RNA Helicases - genetics | Drug Resistance, Neoplasm - genetics | Animals | Adolescent | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice, Inbred NOD | High-Throughput Nucleotide Sequencing | Mice | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Genetic aspects | Nucleotide sequencing | Analysis | Medulloblastoma | Genomics | DNA sequencing | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2015, Volume 27, Issue 5, pp. 728 - 743
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 226 - 231
Journal Article
Blood, ISSN 0006-4971, 12/2010, Volume 116, Issue 23, pp. 4737 - 4738
Journal Article
Cell, ISSN 0092-8674, 01/2012, Volume 148, Issue 1-2, pp. 59 - 71
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 5/2015, Volume 129, Issue 5, pp. 669 - 678
Journal Article