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by Thompson, Eric M, MD and Hielscher, Thomas, MSc and Bouffet, Eric, Prof and Remke, Marc, MD and Luu, Betty, BSc and Gururangan, Sridharan, Prof and McLendon, Roger E, Prof and Bigner, Darell D, Prof and Lipp, Eric S, MD and Perreault, Sebastien, MD and Cho, Yoon-Jae, MD and Grant, Gerald, MD and Kim, Seung-Ki, Prof and Lee, Ji Yeoun, MD and Rao, Amulya A Nageswara, MD and Giannini, Caterina, Prof and Li, Kay Ka Wai, MD and Ng, Ho-Keung, Prof and Yao, Yu, MD and Kumabe, Toshihiro, MD and Tominaga, Teiji, Prof and Grajkowska, Wieslawa A, Prof and Perek-Polnik, Marta, Prof and Low, David C Y, MBBCh and Seow, Wan Tew, MBBS and Chang, Kenneth T E, MBBCh and Mora, Jaume, Prof and Pollack, Ian F, Prof and Hamilton, Ronald L, MD and Leary, Sarah, MD and Moore, Andrew S, PhD and Ingram, Wendy J, PhD and Hallahan, Andrew R, MBBS and Jouvet, Anne, MD and Fèvre-Montange, Michelle, PhD and Vasiljevic, Alexandre, MD and Faure-Conter, Cecile, MD and Shofuda, Tomoko, PhD and Kagawa, Naoki, MD and Hashimoto, Naoya, MD and Jabado, Nada, MD and Weil, Alexander G, MD and Gayden, Tenzin, PhD and Wataya, Takafumi, MD and Shalaby, Tarek, MD and Grotzer, Michael, Prof and Zitterbart, Karel, PhD and Sterba, Jaroslav, Prof and Kren, Leos, MD and Hortobágyi, Tibor, Prof and Klekner, Almos, PhD and László, Bognár, Prof and Pócza, Tímea, MSc and Hauser, Peter, MD and Schüller, Ulrich, MD and Jung, Shin, Prof and Jang, Woo-Youl, MD and French, Pim J, Prof and Kros, Johan M, Prof and van Veelen, Marie-Lise C, MD and Massimi, Luca, MD and Leonard, Jeffrey R, Prof and Rubin, Joshua B, MD and Vibhakar, Rajeev, MD and Chambless, Lola B, MD and Cooper, Michael K, MD and Thompson, Reid C, Prof and Faria, Claudia C, MD and Carvalho, Alice, MD and Nunes, Sofia, MD and Pimentel, José, MD and Fan, Xing, MD and Muraszko, Karin M, Prof and López-Aguilar, Enrique, MD and Lyden, David, Prof and Garzia, Livia, PhD and Shih, David J H, PhD and Kijima, Noriyuki, MD and Schneider, Christian, MD and Adamski, Jennifer, PhD and Northcott, Paul A, PhD and Kool, Marcel, PhD and Jones, David T W, PhD and Chan, Jennifer A, MD and Nikolic, Ana, MD and Garre, Maria Luisa, MD and Van Meir, Erwin G, Prof and Osuka, Satoru, MD and Olson, Jeffrey J, Prof and Jahangiri, Arman, BSc and Castro, Brandyn A, BSc and Gupta, Nalin, MD and Weiss, William A, Prof and Moxon-Emre, Iska, MSc and Mabbott, Donald J, PhD and Lassaletta, Alvaro, MD and Hawkins, Cynthia E, Prof and Tabori, Uri, MD and Drake, James, Prof and Kulkarni, Abhaya, Prof and ...
The Lancet Oncology, ISSN 1470-2045, 2016, Volume 17, Issue 4, pp. 484 - 495
Journal Article
by Northcott, Paul A and Buchhalter, Ivo and Morrissy, A. Sorana and Hovestadt, Volker and Weischenfeldt, Joachim and Ehrenberger, Tobias and Gröbner, Susanne and Segura-Wang, Maia and Zichner, Thomas and Rudneva, Vasilisa A and Warnatz, Hans-Jörg and Sidiropoulos, Nikos and Phillips, Aaron H and Schumacher, Steven and Kleinheinz, Kortine and Waszak, Sebastian M and Erkek, Serap and Jones, David T. W and Worst, Barbara C and Kool, Marcel and Zapatka, Marc and Jäger, Natalie and Chavez, Lukas and Hutter, Barbara and Bieg, Matthias and Paramasivam, Nagarajan and Heinold, Michael and Gu, Zuguang and Ishaque, Naveed and Jäger-Schmidt, Christina and Imbusch, Charles D and Jugold, Alke and Hübschmann, Daniel and Risch, Thomas and Amstislavskiy, Vyacheslav and Gonzalez, Francisco German Roiguez and Weber, Ursula D and Wolf, Stephan and Robinson, Giles W and Zhou, Xin and Wu, Gang and Finkelstein, David and Liu, Yanling and Cavalli, Florence M. G and Luu, Betty and Ramaswamy, Vijay and Wu, Xiaochong and Koster, Jan and Ryzhova, Marina and Cho, Yoon-Jae and Pomeroy, Scott L and Herold-Mende, Christel and Schuhmann, Martin and Ebinger, Martin and Liau, Linda M and Mora, Jaume and McLendon, Roger E and Jabado, Nada and Kumabe, Toshihiro and Chuah, Eric and Ma, Yussanne and Moore, Richard A and Mungall, Anew J and Mungall, Karen L and Thiessen, Nina and Tse, Kane and Wong, Tina and Jones, Steven J. M and Witt, Olaf and Milde, Till and von Deimling, Aneas and Capper, David and Korshunov, Aney and Yaspo, Marie-Laure and Kriwacki, Richard and Gajjar, Amar and Zhang, Jinghui and Beroukhim, Rameen and Fraenkel, Ernest and Korbel, Jan O and Brors, Benedikt and Schlesner, Matthias and Eils, Roland and Marra, Marco A and Pfister, Stefan M and Taylor, Michael D and Lichter, Peter
Nature, ISSN 0028-0836, 2017, Volume 547, Issue 7663, pp. 311 - 317
Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose debilitating effects on the developing child, and highlight the need... 
MUTATIONAL PROCESSES | METHYLATION | SIGNATURES | DATABASE | GENE | COPY-NUMBER | MULTIDISCIPLINARY SCIENCES | SUBGROUPS | CANCER | TUMORS | FAMILY | Medical research | Medulloblastoma | Medicine, Experimental | Genomes | Genetic aspects | Research | Nucleotide sequencing | Varieties | DNA sequencing | Brain | Toxicity | Brain tumors | Brain cancer | Genes | Genomics | Biodiversity | Patients | Heterogeneity | DNA methylation | Mutation | Children
Journal Article
by Northcott, Paul A and Shih, David J. H and Peacock, John and Garzia, Livia and Sorana Morrissy, A and Zichner, Thomas and Stútz, Adrian M and Korshunov, Andrey and Reimand, Júri and Schumacher, Steven E and Beroukhim, Rameen and Ellison, David W and Marshall, Christian R and Lionel, Anath C and MacK, Stephen and Dubuc, Adrian and Yao, Yuan and Ramaswamy, Vijay and Luu, Betty and Rolider, Adi and Cavalli, Florence M. G and Wang, Xin and Remke, Marc and Wu, Xiaochong and Chiu, Readman Y. B and Chu, Andy and Chuah, Eric and Corbett, Richard D and Hoad, Gemma R and Jackman, Shaun D and Li, Yisu and Lo, Allan and Mungall, Karen L and Ming Nip, Ka and Qian, Jenny Q and Raymond, Anthony G. J and Thiessen, Nina and Varhol, Richard J and Birol, Inanc and Moore, Richard A and Mungall, Andrew J and Holt, Robert and Kawauchi, Daisuke and Roussel, Martine F and Kool, Marcel and Jones, David T. W and Witt, Hendrick and Fernandez-L, Africa and Kenney, Anna M and Wechsler-Reya, Robert J and Dirks, Peter and Aviv, Tzvi and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Haberler, Christine C and Delattre, Olivier and Reynaud, Stéphanie S and Doz, François F and Pernet-Fattet, Sarah S and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Scheurlen, Wolfram and Eberhart, Charles G and Fèvre-Montange, Michelle and Jouvet, Anne and Pollack, Ian F and Fan, Xing and Muraszko, Karin M and Yancey Gillespie, G and Di Rocco, Concezio and Massimi, Luca and Michiels, Erna M. C and Kloosterhof, Nanne K and French, Pim J and Kros, Johan M and Olson, James M and Ellenbogen, Richard G and Zitterbart, Karel and Kren, Leos and Thompson, Reid C and Cooper, Michael K and Lach, Boleslaw and McLendon, Roger E and Bigner, Darell D and Fontebasso, Adam and Albrecht, Steffen and Jabado, Nada and Lindsey, Janet C and Bailey, Simon and Gupta, Nalin and Weiss, William A and Bognár, László and Klekner, Almos and Van Meter, Timothy E and Kumabe, Toshihiro and Tominaga, Teiji and Elbabaa, Samer K and Leonard, Jeffrey R and Rubin, Joshua B and ...
Nature, ISSN 0028-0836, 08/2012, Volume 487, Issue 7409, pp. 49 - 56
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2013, Volume 31, Issue 23, pp. 2927 - 2935
Journal Article
by Morrissy, A. Sorana and Garzia, Livia and Shih, David J. H and Zuyderduyn, Scott and Huang, Xi and Skowron, Patryk and Remke, Marc and Cavalli, Florence M. G and Ramaswamy, Vijay and Lindsay, Patricia E and Jelveh, Salomeh and Donovan, Laura K and Wang, Xin and Luu, Betty and Zayne, Kory and Li, Yisu and Mayoh, Chelsea and Thiessen, Nina and Mercier, Eloi and Mungall, Karen L and Ma, Yusanne and Tse, Kane and Zeng, Thomas and Shumansky, Karey and Roth, Andrew J. L and Shah, Sohrab and Farooq, Hamza and Kijima, Noriyuki and Holgado, Borja L and Lee, John J. Y and Matan-Lithwick, Stuart and Liu, Jessica and Mack, Stephen C and Manno, Alex and Michealraj, K.A and Nor, Carolina and Peacock, John and Qin, Lei and Reimand, Juri and Rolider, Adi and Thompson, Yuan Y and Wu, Xiaochong and Pugh, Trevor and Ally, Adrian and Bilenky, Mikhail and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Young and Chuah, Eric and Corbett, Richard D and Dhalla, Noreen and He, An and Lee, Darlene and Li, Haiyan I and Long, William and Mayo, Michael and Plettner, Patrick and Qian, Jenny Q and Schein, Jacqueline E and Tam, Angela and Wong, Tina and Birol, Inanc and Zhao, Yongjun and Faria, Claudia C and Pimentel, José and Nunes, Sofia and Shalaby, Tarek and Grotzer, Michael and Pollack, Ian F and Hamilton, Ronald L and Li, Xiao-Nan and Bendel, Anne E and Fults, Daniel W and Walter, Andrew W and Kumabe, Toshihiro and Tominaga, Teiji and Collins, V. Peter and Cho, Yoon-Jae and Hoffman, Caitlin and Lyden, David and Wisoff, Jeffrey H and Garvin, James H and Stearns, Duncan S and Massimi, Luca and Schüller, Ulrich and Sterba, Jaroslav and Zitterbart, Karel and Puget, Stephanie and Ayrault, Olivier and Dunn, Sandra E and Tirapelli, Daniela P. C and Carlotti, Carlos G and Wheeler, Helen and Hallahan, Andrew R and Ingram, Wendy and MacDonald, Tobey J and Olson, Jeffrey J and Van Meir, Erwin G and Lee, Ji-Yeoun and Wang, Kyu-Chang and ...
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7586, pp. 351 - 357
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related... 
HETEROGENEITY | CANCER EVOLUTION | CELLS | IMPACT | MULTIDISCIPLINARY SCIENCES | SUBGROUP MEDULLOBLASTOMA | DYNAMICS | MUTATIONS | SEQUENCING DATA | LYMPHOBLASTIC-LEUKEMIA | GENOME | Clone Cells - drug effects | Humans | Male | Medulloblastoma - therapy | Radiotherapy, Image-Guided | Selection, Genetic - drug effects | Drosophila melanogaster - genetics | Neoplasm Recurrence, Local - pathology | Medulloblastoma - radiotherapy | DNA Mutational Analysis | Medulloblastoma - pathology | Female | Medulloblastoma - surgery | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Molecular Targeted Therapy - methods | Disease Models, Animal | Signal Transduction | Neoplasm Recurrence, Local - therapy | Drosophila melanogaster - cytology | Cerebellar Neoplasms - genetics | Clone Cells - metabolism | Genome, Human - genetics | Xenograft Model Antitumor Assays | Animals | Clone Cells - pathology | Craniospinal Irradiation | Neoplasm Recurrence, Local - genetics | Mice | Cerebellar Neoplasms - therapy | Cerebellar Neoplasms - surgery | Cerebellar Neoplasms - radiotherapy | Clonal selection theory | Care and treatment | Medulloblastoma | Oncology, Experimental | Genetic aspects | Research | Cancer | Genes | Cloning | Clinical trials | Cytotoxicity | Genomes | Radiation therapy | Metastasis | Cancer therapies | Rodents | Medical prognosis | Mutation | Tumors | Index Medicus
Journal Article
by Cavalli, Florence M.G and Remke, Marc and Rampasek, Ladislav and Peacock, John and Shih, David J.H and Luu, Betty and Garzia, Livia and Torchia, Jonathon and Nor, Carolina and Morrissy, A. Sorana and Agnihotri, Sameer and Thompson, Reid C and Thompson, Yuan Yao and Kuzan-Fischer, Claudia M and Farooq, Hamza and Isaev, Keren and Daniels, Craig and Cho, Byung-Kyu and Kim, Seung-Ki and Wang, Kyu-Chang and Lee, Ji Yeoun and Grajkowska, Wieslawa A and Perek-Polnik, Marta and Vasiljevic, Alexandre and Faure-Conter, Cecile and Jouvet, Anne and Giannini, Caterina and Nageswara Rao, Amulya A and Li, Kay Ka Wai and Ng, Ho-Keung and Eberhart, Charles G and Pollack, Ian F and Hamilton, Ronald L and Gillespie, G. Yancey and Olson, James M and Leary, Sarah and Weiss, William A and Lach, Boleslaw and Chambless, Lola B and Cooper, Michael K and Vibhakar, Rajeev and Hauser, Peter and van Veelen, Marie-Lise C and Kros, Johan M and French, Pim J and Ra, Young Shin and Kumabe, Toshihiro and López-Aguilar, Enrique and Zitterbart, Karel and Sterba, Jaroslav and Finocchiaro, Gaetano and Massimino, Maura and Van Meir, Erwin G and Osuka, Satoru and Shofuda, Tomoko and Klekner, Almos and Zollo, Massimo and Leonard, Jeffrey R and Rubin, Joshua B and Jabado, Nada and Albrecht, Steffen and Mora, Jaume and Van Meter, Timothy E and Jung, Shin and Moore, Andrew S and Hallahan, Andrew R and Chan, Jennifer A and Tirapelli, Daniela P.C and Carlotti, Carlos G and Fouladi, Maryam and Pimentel, José and Faria, Claudia C and Saad, Ali G and Massimi, Luca and Liau, Linda M and Wheeler, Helen and Nakamura, Hideo and Elbabaa, Samer K and Perezpeña-Diazconti, Mario and Chico Ponce de León, Fernando and Robinson, Shenandoah and Zapotocky, Michal and Lassaletta, Alvaro and Huang, Annie and Hawkins, Cynthia E and Tabori, Uri and Bouffet, Eric and Bartels, Ute and Dirks, Peter B and Rutka, James T and Bader, Gary D and Reimand, Jüri and Goldenberg, Anna and Ramaswamy, Vijay and Taylor, Michael D
Cancer Cell, ISSN 1535-6108, 06/2017, Volume 31, Issue 6, pp. 737 - 754.e6
Journal Article