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by Hoshino, Ayuko and Costa-Silva, Bruno and Shen, Tang-Long and Rodrigues, Goncalo and Hashimoto, Ayako and Tesic Mark, Milica and Molina, Henrik and Kohsaka, Shinji and Di Giannatale, Angela and Ceder, Sophia and Singh, Swarnima and Williams, Caitlin and Soplop, Nadine and Uryu, Kunihiro and Pharmer, Lindsay and King, Tari and Bojmar, Linda and Davies, Alexander E and Ararso, Yonathan and Zhang, Tuo and Zhang, Haiying and Hernandez, Jonathan and Weiss, Joshua M and Dumont-Cole, Vanessa D and Kramer, Kimberly and Wexler, Leonard H and Narendran, Aru and Schwartz, Gary K and Healey, John H and Sandstrom, Per and Jørgen Labori, Knut and Kure, Elin H and Grandgenett, Paul M and Hollingsworth, Michael A and De Sousa, Maria and Kaur, Sukhwinder and Jain, Maneesh and Mallya, Kavita and Batra, Surinder K and Jarnagin, William R and Brady, Mary S and Fodstad, Oystein and Muller, Volkmar and Pantel, Klaus and Minn, Andy J and Bissell, Mina J and Garcia, Benjamin A and Kang, Yibin and Rajasekhar, Vinagolu K and Ghajar, Cyrus M and Matei, Irina and Peinado, Hector and Bromberg, Jacqueline and Lyden, David and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Weill Cornell Medicine, New York, NY (United States) and Memorial Sloan Kettering Cancer Center, New York, NY (United States) and Medicinska fakulteten and Region Östergötland and Kirurgiska kliniken US and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Avdelningen för kliniska vetenskaper and Centrum för kirurgi, ortopedi och cancervård
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 329 - 335
Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from... 
CELLS | BONE METASTASES | VESICLES | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | NICHE | MICROVESICLES | PROTEINS | PROTEOMICS | Exosomes - metabolism | Tropism | Phosphorylation | Epithelial Cells - metabolism | Receptors, Vitronectin - antagonists & inhibitors | Humans | Lung - cytology | Integrin beta4 - metabolism | Integrins - metabolism | Brain - metabolism | Integrin alpha6beta1 - metabolism | S100 Proteins - genetics | Neoplasm Metastasis - prevention & control | Female | Kupffer Cells - metabolism | Lung - metabolism | Receptors, Vitronectin - metabolism | Epithelial Cells - cytology | Integrin alpha6beta4 - metabolism | Fibroblasts - metabolism | Biomarkers - metabolism | Brain - cytology | Kupffer Cells - cytology | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Integrin alpha6beta4 - antagonists & inhibitors | Organ Specificity | Animals | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Cell Line, Tumor | Integrin beta Chains - metabolism | Fibroblasts - cytology | Liver - cytology | Mice | Genes, src | Integrins - antagonists & inhibitors | Complications and side effects | Development and progression | Cell organelles | Metastasis | Health aspects | Integrins | Tumors | Studies | Microscopy | Liver | Melanoma | Fibroblasts | Breast cancer | Chemokines | Index Medicus | mechanisms of disease | cancer microenvironment | BASIC BIOLOGICAL SCIENCES | metastasis | 60 APPLIED LIFE SCIENCES | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Neuron, ISSN 0896-6273, 12/2013, Volume 80, Issue 5, pp. 1175 - 1189
Axon degeneration is widespread both in neurodegenerative disease and in normal neural development, but the molecular pathways regulating these degenerative... 
PERIPHERAL-NERVE | APOPTOSIS | ACTIVATION | UBIQUITIN-PROTEASOME SYSTEM | PATHWAY | WALLERIAN DEGENERATION | DISEASE | DEATH | CLEAVAGE | FRAGMENTATION | NEUROSCIENCES | Neurons - pathology | Calpain - metabolism | Wallerian Degeneration - pathology | Cytoskeletal Proteins - genetics | Embryo, Mammalian | Nicotinamide-Nucleotide Adenylyltransferase - metabolism | Humans | Cell Survival - genetics | Ganglia, Spinal - cytology | Green Fluorescent Proteins - genetics | Armadillo Domain Proteins - genetics | RNA, Messenger - metabolism | Sciatic Neuropathy - complications | Nerve Degeneration - metabolism | Axotomy | Neurons - ultrastructure | Time Factors | HEK293 Cells | Cytoskeletal Proteins - metabolism | Disease Models, Animal | Animals, Newborn | Calcium-Binding Proteins - metabolism | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Brain - cytology | Nerve Growth Factor - metabolism | Transduction, Genetic | Wallerian Degeneration - physiopathology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Ganglia, Spinal - ultrastructure | Nerve Tissue Proteins - metabolism | Animals | Armadillo Domain Proteins - metabolism | Nicotinamide-Nucleotide Adenylyltransferase - genetics | Mice | In Vitro Techniques | Nerve Degeneration - etiology | Sciatic Neuropathy - metabolism | Calcium-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Physiological aspects | Calpain | Nervous system diseases | Analysis | Medical research | Microscopy | Mammals | Neurodegeneration | Lasers | Index Medicus
Journal Article
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 9/2007, Volume 114, Issue 3, pp. 221 - 229
Journal Article
Cell Reports, ISSN 2211-1247, 08/2014, Volume 8, Issue 4, pp. 957 - 965
Vertebrate centrioles lose their geometric scaffold, the cartwheel, during mitosis, concurrently with gaining the ability to recruit the pericentriolar... 
PROCENTRIOLE | PROTEIN | CPAP | HUMAN-CELLS | 9-FOLD SYMMETRY | POLO | SAS-6 | CYCLE | CELL BIOLOGY | Cell Line | Proteins - physiology | Centrioles - physiology | Humans | Cell Cycle Proteins | Centrosome - metabolism | Index Medicus
Journal Article