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Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5005
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2015, Volume 464, Issue 2, pp. 386 - 391
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 4, pp. 1001 - 1011
Purpose: Cancer treatments using tumor defects in DNA repair pathways have shown promising results but are restricted to small subpopulations of patients. The... 
POLY(ADP-RIBOSE) POLYMERASE | NETWORK | THERAPEUTIC STRATEGY | ONCOLOGY | MUTANT-CELLS | BRCA MUTATION CARRIERS | SUSCEPTIBILITY | HOMOLOGOUS RECOMBINATION | OVARIAN-CANCER | DNA-REPAIR | DAMAGE | DNA End-Joining Repair - drug effects | Piperazines - administration & dosage | Phthalazines - administration & dosage | Tumor Suppressor p53-Binding Protein 1 - genetics | Rad51 Recombinase - genetics | Humans | Poly(ADP-ribose) Polymerase Inhibitors - adverse effects | Piperazines - adverse effects | Neoplasms - drug therapy | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | X-ray Repair Cross Complementing Protein 1 - genetics | Poly(ADP-ribose) Polymerases - genetics | Neoplasms - genetics | Synthetic Lethal Mutations - drug effects | Cell Line, Tumor | Homologous Recombination - genetics | Gene Expression Regulation, Neoplastic - drug effects | Neoplasms - pathology | Phthalazines - adverse effects | Drugs | DNA damage | Homologous recombination | Homology | Lethality | Damage prevention | Cancer therapies | DNA repair | Recruitment | Pathways | Genetics | Repair | Damage accumulation | Deoxyribonucleic acid--DNA | Subpopulations | XRCC1 protein | Sensitivity analysis | Cell survival | Tumor cells | Poly(ADP-ribose) polymerase | Breast cancer | Tumor cell lines | Gene expression | Inhibitors | Experimental design | Cell death | Multilevel | Cell lines | Combined treatment | Auditory defects | Tumors | Cancer
Journal Article
Nature Protocols, ISSN 1754-2189, 03/2019, Volume 14, Issue 3, pp. 639 - 702
Journal Article
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 08/2019, Volume 431, Issue 17, pp. 3056 - 3067
Journal Article
Database : the journal of biological databases and curation, ISSN 1758-0463, 01/2017, Volume 2017, Issue 1
Human diseases such as cancer are routinely characterized by high-throughput molecular technologies, and multi-level omics data are accumulated in public... 
PATHWAYS | ATLAS | ENVIRONMENT | MATHEMATICAL & COMPUTATIONAL BIOLOGY | CYTOSCAPE | KEGG | CANCER | SYSTEMS BIOLOGY | Neoplasms - metabolism | Internet | Humans | Computational Biology
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 04/2013, Volume 9, Issue 4
  Systematic analysis of synthetic lethality (SL) constitutes a critical tool for systems biology to decipher molecular pathways. The most accepted mechanistic... 
Yeast | Genes | Homeostasis | Biology | Biosynthesis | Genomes | Mammals | DNA repair | Defects | Studies | Signal transduction | Ordinary differential equations | Mathematical models | Mutation | Cancer
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2008, Volume 27, Issue 1, pp. 224 - 233
Although soluble oligomeric and protofibrillar assemblies of Aβ‐amyloid peptide cause synaptotoxicity and potentially contribute to Alzheimer's disease (AD),... 
amyloidosis | amyloid fibril | Alzheimer's disease | lipid | Amyloidosis | Amyloid fibril | Lipid | CASCADE HYPOTHESIS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMMON MECHANISM | SYNAPTIC PLASTICITY | PEPTIDE | CELL BIOLOGY | IN-VIVO | PROTEIN FIBRILLOGENESIS | CELL-CULTURE | PRECURSOR PROTEIN | SECRETED OLIGOMERS
Journal Article