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1. Full Text ACL Injury and Its Treatment
by Mitsuo Ochi Ochi and Konsei Shino Shino and Kazunori Yasuda Yasuda and Masahiro Kurosaka Kurosaka and Masahiro and Kazunori and Konsei and Mitsuo
06/2016, 1st ed. 2016, ISBN 443155856X, 546
This volume presents detailed information on surgically relevant anatomy and histology of the anterior cruciate ligament (ACL), biomechanics, diagnostics, and... 
Surgery | Rehabilitation | Surgical Orthopedics | Medicine & Public Health | Sports Medicine
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2. Full Text Dreams come true: the soul and spirit of orthopaedics
by Kurosaka, Masahiro
Journal of Orthopaedic Science, ISSN 0949-2658, 03/2014, Volume 19, Issue 2, pp. 205 - 206
Medicine & Public Health | Orthopedics | Rheumatology | ORTHOPEDICS | Congresses as Topic | Societies, Medical | Humans | Japan | Career Choice | Biomedical Research - trends | Orthopedics - trends
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3. Full Text Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice
by Matsuzaki, Tokio and Matsushita, Takehiko and Takayama, Koji and Matsumoto, Tomoyuki and Nishida, Kotaro and Kuroda, Ryosuke and Kurosaka, Masahiro
Annals of the Rheumatic Diseases, ISSN 0003-4967, 07/2014, Volume 73, Issue 7, pp. 1397 - 1404
Objectives Important roles for SIRT1 are implicated in ageing and age-related diseases. The role of SIRT1 in osteoarthritis (OA), however, remains partially... 
TRANSCRIPTION FACTORS | APOPTOSIS | PROTEIN | PATHWAY | INTERLEUKIN-1-BETA | GENE-EXPRESSION | FACTOR-KAPPA-B | TNF-ALPHA | RHEUMATOLOGY | HISTONE DEACETYLASE | CARTILAGE | Sirtuin 1 - metabolism | Arthritis, Experimental - genetics | Arthritis, Experimental - physiopathology | Cartilage, Articular - cytology | Mice, Inbred C57BL | Stress, Mechanical | Sirtuin 1 - genetics | Disease Progression | Arthritis, Experimental - metabolism | Mice, Knockout | Animals | Aging - genetics | Aging - physiology | Chondrocytes - physiology | Cartilage, Articular - metabolism | Osteoarthritis, Knee - genetics | Sirtuin 1 - physiology | Mice | Osteoarthritis, Knee - physiopathology | Chondrocytes - metabolism | Osteoarthritis, Knee - metabolism | Aging - metabolism | Disease Models, Animal | Stress relieving (Materials) | Care and treatment | Strains and stresses | Analysis | Diagnosis | Cartilage cells | Osteoarthritis | Stress relaxation (Materials) | Knee | Enzymes | Rodents | Surgery | Aging | Roles | Gene expression | Age | Apoptosis
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4. Full Text Clinical outcomes of medial patellofemoral ligament reconstruction in patients with an increased tibial tuberosity–trochlear groove distance
by Matsushita, Takehiko and Kuroda, Ryosuke and Oka, Shinya and Matsumoto, Tomoyuki and Takayama, Koji and Kurosaka, Masahiro
Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, 10/2014, Volume 22, Issue 10, pp. 2438 - 2444
Medial patellofemoral ligament (MPFL) reconstruction is performed to treat recurrent patellar dislocation (RPD). However, the effectiveness of MPFL... 
Tibial tuberosity–trochlear groove distance | Medial patellofemoral ligament reconstruction | Medicine & Public Health | Recurrent patellar dislocation | Orthopedics | SOFT-TISSUE RESTRAINTS | KNEE | SURGERY | SPORT SCIENCES | INSTABILITY | INJURIES | RELEASE | ANATOMY | REPAIR | Tibial tuberosity-trochlear groove distance | COMPLICATIONS | ORTHOPEDICS | Patellar Dislocation - surgery | Humans | Knee Joint - diagnostic imaging | Tibia - diagnostic imaging | Ligaments, Articular - surgery | Male | Case-Control Studies | Tibia - surgery | Radiography | Young Adult | Knee Joint - surgery | Adolescent | Adult | Female | Retrospective Studies | Orthopedic surgery
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5. Full Text Double-bundle ACL reconstruction can improve rotational stability
by Yagi, Masayoshi and Kuroda, Ryosuke and Nagamune, Kouki and Yoshiya, Shinichi and Kurosaka, Masahiro
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 01/2007, Volume 454, Issue 454, pp. 100 - 107
Double-bundle anterior cruciate ligament (ACL) reconstruction reproduces anteromedial and posterolateral bundles, and thus has theoretical advantages over... 
PATELLAR TENDON | KNEE | SURGERY | MULTISTRANDED HAMSTRING TENDONS | SEMITENDINOSUS | GRAFTS | IN-SITU FORCES | BIOMECHANICAL ANALYSIS | PIVOT SHIFT | ANTERIOR CRUCIATE LIGAMENT | ORTHOPEDICS | LOADS | Anterior Cruciate Ligament - surgery | Prospective Studies | Humans | Knee Joint - physiopathology | Orthopedic Procedures - methods | Male | Treatment Outcome | Tendons - transplantation | Joint Instability - surgery | Knee Joint - surgery | Biomechanical Phenomena | Electromagnetic Phenomena - methods | Anterior Cruciate Ligament - physiopathology | Tendons - surgery | Range of Motion, Articular - physiology | Adolescent | Adult | Female | Orthopedic Procedures - economics | Joint Instability - physiopathology
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6. Full Text Causative factors of fracture nonunion: the proportions of mechanical, biological, patient-dependent, and patient-independent factors
by Niikura, Takahiro and Yang Lee, Sang and Sakai, Yoshitada and Nishida, Kotaro and Kuroda, Ryosuke and Kurosaka, Masahiro
Journal of Orthopaedic Science, ISSN 0949-2658, 01/2014, Volume 19, Issue 1, pp. 120 - 124
Understanding the causative factors of fracture nonunion leads to both prevention and improvements in treatment. The purpose of this study was to understand... 
Medicine & Public Health | Orthopedics | Rheumatology | CIGARETTE-SMOKING | RISK-FACTORS | DIAPHYSIS | CLASSIFICATION | COMPLICATIONS | ORTHOPEDICS | FEMORAL FRACTURES | Japan - epidemiology | Fracture Fixation, Internal - adverse effects | Follow-Up Studies | Humans | Middle Aged | Fractures, Ununited - diagnostic imaging | Male | Fractures, Ununited - etiology | Incidence | Young Adult | Hand Injuries - surgery | Time Factors | Aged, 80 and over | Adult | Female | Fractures, Comminuted - surgery | Fractures, Ununited - epidemiology | Fractures, Comminuted - diagnostic imaging | Leg Injuries - diagnostic imaging | Risk Factors | Hand Injuries - diagnostic imaging | Radiography | Fracture Healing | Adolescent | Aged | Leg Injuries - surgery | Medical colleges | Fractures | Nuclear radiation | Alcoholism | Analysis | Surgeons | Diabetes | Health aspects
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7. Full Text Intraoperative posterior movement of the tibia at 90° of flexion predicts worse postoperative flexion angles in cruciate-substituting total knee arthroplasty
by Inokuchi, Takao and Ishida, Kazunari and Takayama, Koji and Shibanuma, Nao and Hayashi, Shinya and Kurosaka, Masahiro and Kuroda, Ryosuke and Matsumoto, Tomoyuki
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, ISSN 0942-2056, 07/2019, pp. 1 - 7
To investigate the correlation between intraoperative tibiofemoral anteroposterior changes at 90° of flexion and postoperative maximum flexion angles in... 
Knee | Surgical implants | Correlation | Navigation | Arthroplasty (knee) | Knee (anatomy) | Joint surgery | Rotation | Biomedical materials | Tibia | Kinematics | Navigation systems | Comparative studies | Biocompatibility | Inserts | Osteoarthritis
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8. Full Text Profiling microRNA expression during fracture healing
by Waki, Takahiro and Lee, Sang Yang and Niikura, Takahiro and Iwakura, Takashi and Dogaki, Yoshihiro and Okumachi, Etsuko and Oe, Keisuke and Kuroda, Ryosuke and Kurosaka, Masahiro
BMC Musculoskeletal Disorders, ISSN 1471-2474, 02/2016, Volume 17, Issue 1, p. 83
Background: The discovery of microRNA (miRNA) has revealed a novel type of regulatory control for gene expression. Increasing evidence suggests that miRNA... 
microRNA | Fracture healing | Bone | Microarray | ACTIVATION | RAT FEMUR | MODEL | RHEUMATOLOGY | THERAPEUTIC APPLICATIONS | REPAIR | BONE-FORMATION | NONUNION | GENE-EXPRESSION | OSTEOPOROTIC FRACTURES | DIFFERENTIATION | ORTHOPEDICS | Femoral Neck Fractures - diagnostic imaging | Femoral Neck Fractures - genetics | Gene Expression Regulation | Rats | Gene Expression Profiling - methods | Male | MicroRNAs - biosynthesis | Femoral Neck Fractures - metabolism | Rats, Sprague-Dawley | Radiography | Animals | MicroRNAs - genetics | Fracture Healing - genetics | Care and treatment | Fractures | MicroRNA | Analysis | Influence | Research | Gene expression
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9. Full Text Intra-articular tranexamic acid as an adjunct to intravenous tranexamic acid for simultaneous bilateral total knee arthroplasty: a randomized double-blind, placebo-controlled trial
by Tsukada, S and Kurosaka, K and Nishino, M and Maeda, T and Yonekawa, Y and Hirasawa, N
BMC MUSCULOSKELETAL DISORDERS, ISSN 1471-2474, 10/2019, Volume 20, Issue 1, pp. 1 - 7
BackgroundIntra-articular tranexamic acid (TXA) as an adjunct to intravenous TXA was reported to decrease perioperative blood loss during unilateral total knee... 
Knee | IMPACT | Transfusion | BLOOD-LOSS | Blood loss | Complication | RHEUMATOLOGY | Primary arthroplasty | ORTHOPEDICS
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10. Full Text Expression and Function of Histone Deacetylases in Rheumatoid Arthritis Synovial Fibroblasts
by MARIKA HORIUCHI and AKIO MORINOBU and TAKAAKI CHIN and YOSHITADA SAKAI and MASAHIRO KUROSAKA and SHUNICHI KUMAGAI
The Journal of Rheumatology, ISSN 0315-162X, 08/2009, Volume 36, Issue 8, pp. 1580 - 1589
Objective. To explore the effects of histone deacetylases (HDAC) on rheumatoid arthritis synovial fibroblasts (RA-SF). Methods. The expression of mRNA encoding... 
Histone deacetylase | Synovial fibroblast | Matrix metalloprotease | siRNA | Rheumatoid arthritis | APOPTOSIS | CELLS | MESSENGER-RNA EXPRESSION | RHEUMATOLOGY | PATHOGENESIS | MATRIX METALLOPROTEASE | GASTRIC-CANCER | SYNOVIAL FIBROBLAST | HUMAN COLON-CANCER | GROWTH | RHEUMATOID ARTHRITIS | TNF-ALPHA | INHIBITORS | HISTONE DEACETYLASE | TRICHOSTATIN | Fibroblasts - enzymology | Histone Deacetylases - genetics | Cell Count | Humans | Cells, Cultured | Osteoarthritis - metabolism | Repressor Proteins - genetics | Histone Deacetylase 2 | Gene Expression Regulation, Enzymologic - physiology | RNA, Messenger - metabolism | Osteoarthritis - physiopathology | Synovial Membrane - metabolism | Histone Deacetylase 1 | Arthritis, Rheumatoid - pathology | Cell Division - physiology | Arthritis, Rheumatoid - metabolism | Fibroblasts - cytology | RNA, Small Interfering | Apoptosis - physiology | Osteoarthritis - pathology | Matrix Metalloproteinase 1 - metabolism | Synovial Membrane - physiopathology | Arthritis, Rheumatoid - physiopathology
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11. Full Text In Vivo Measurement of the Pivot-Shift Test in the Anterior Cruciate Ligament—Deficient Knee Using an Electromagnetic Device
by Hoshino, Yuichi and Kuroda, Ryosuke and Nagamune, Kouki and Yagi, Masayoshi and Mizuno, Kiyonori and Yamaguchi, Motoi and Muratsu, Hirotsugu and Yoshiya, Shinichi and Kurosaka, Masahiro
The American Journal of Sports Medicine, ISSN 0363-5465, 7/2007, Volume 35, Issue 7, pp. 1098 - 1104
Background The pivot-shift test is commonly used for assessing dynamic instability in anterior cruciate ligament—insufficient knees, which is related to... 
ACL injury | Dynamic instability | Pivot-shift test | Electromagnetic device | pivot-shift test | SPORT SCIENCES | electromagnetic device | RECONSTRUCTION | LAXITY | ANTEROPOSTERIOR | STABILITY | INJURY | MOTIONS | ORTHOPEDICS | JOINT | dynamic instability | KINEMATICS | Anterior Cruciate Ligament - surgery | Joint Instability - diagnosis | Movement | Knee - physiology | Tibia - physiology | Electromagnetic Phenomena - instrumentation | Anterior Cruciate Ligament Injuries | Humans | Male | Knee Injuries - surgery | Joint Instability - surgery | Pilot Projects | Adolescent | Adult | Female | Knee Injuries - diagnosis | Reconstructive Surgical Procedures | Knee | Electromagnetic measurements | Diagnosis | Analysis | Anterior cruciate ligament | Injuries | Joint and ligament injuries | Ligaments | Skin & tissue grafts | Orthopedics | Sports medicine
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12. Full Text SDF‐1/CXCR4 Axis in Tie2‐Lineage Cells Including Endothelial Progenitor Cells Contributes to Bone Fracture Healing
by Kawakami, Yohei and Ii, Masaaki and Matsumoto, Tomoyuki and Kuroda, Ryosuke and Kuroda, Tomoya and Kwon, Sang‐Mo and Kawamoto, Atsuhiko and Akimaru, Hiroshi and Mifune, Yutaka and Shoji, Taro and Fukui, Tomoaki and Kurosaka, Masahiro and Asahara, Takayuki
Journal of Bone and Mineral Research, ISSN 0884-0431, 01/2015, Volume 30, Issue 1, pp. 95 - 105
ABSTRACT CXC chemokine receptor 4 (CXCR4) is a specific receptor for stromal‐derived‐factor 1 (SDF‐1). SDF‐1/CXCR4 interaction is reported to play an important... 
CX CHEMOKINE RECEPTOR 4 (CXCR4) | STROMAL‐DERIVED FACTOR‐1 (SDF‐1) | KNOCKOUT MICE | ENDOTHELIAL PROGENITOR CELL (EPC) | FRACTURE HEALING | Knockout mice | Fracture healing | Stromal-derived factor-1 (SDF-1) | CX chemokine receptor 4 (CXCR4) | Endothelial progenitor cell (EPC) | STIMULATING FACTOR | MARROW | CHEMOKINE RECEPTOR CXCR4 | STROMAL-DERIVED FACTOR-1 (SDF-1) | MESENCHYMAL STEM-CELLS | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | MOLECULAR-CLONING | MICE | DELAYED UNION | LOCAL TRANSPLANTATION | CD34-POSITIVE CELLS | Fractures, Bone - diet therapy | Cells, Cultured | Bone Regeneration | Fractures, Bone - genetics | Fractures, Bone - metabolism | Mice, Knockout | Receptor, TIE-2 - genetics | Receptors, CXCR4 - metabolism | Antigens, Differentiation - biosynthesis | Animals | Chemokine CXCL12 - genetics | Chemokine CXCL12 - metabolism | Endothelial Progenitor Cells - pathology | Chemokine CXCL12 - pharmacology | Receptor, TIE-2 - metabolism | Receptors, CXCR4 - genetics | Antigens, Differentiation - genetics | Fractures, Bone - pathology | Mice | Endothelial Progenitor Cells - metabolism | Bone morphogenetic proteins | Fractures | Endothelial growth factors | Gene expression | Collagen | Endothelium
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13. Full Text Pseudoaneurysm of the articular branch of the descending genicular artery following double-bundle anterior cruciate ligament reconstruction
by Tsubosaka, Masanori and Tsubosaka, Masanori and Matsushita, Takehiko and Matsushita, Takehiko and Kuroda, Ryosuke and Kuroda, Ryosuke and Matsumoto, Tomoyuki and Matsumoto, Tomoyuki and Kurosaka, Masahiro and Kurosaka, Masahiro
Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, 9/2017, Volume 25, Issue 9, pp. 2721 - 2724
This report describes a case of a pseudoaneurysm of the articular branch of the descending genicular artery following double-bundle anterior cruciate ligament... 
Anterior cruciate ligament reconstruction | Arthroscopy | Medicine & Public Health | Articular branch of descending genicular artery | Orthopedics | Pseudoaneurysm | SURGERY | SPORT SCIENCES | COMPLICATION | ACL RECONSTRUCTION | ARTHROSCOPIC MENISCECTOMY | ANEURYSM | ORTHOPEDICS | Anterior Cruciate Ligament Reconstruction - methods | Aneurysm, False - etiology | Humans | Adolescent | Knee Joint - blood supply | Male | Aneurysm, False - diagnosis | Anterior Cruciate Ligament Injuries - surgery | Arteries | Postoperative Complications - diagnosis | Medical colleges | Orthopedic surgery | Ultrasound imaging | Tunnels | Knee | Drilling | Reconstruction | Femur | Knee (anatomy) | Doppler effect | Anterior cruciate ligament | Bundling | Computed tomography | Skin & tissue grafts | Ultrasonography | Embolization
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14. Full Text Intraoperative loose flexion gap may restrict postoperative knee flexion after J-curve design posterior-stabilized total knee arthroplasty
by Tsukada, Sachiyuki and Kurosaka, Kenji and Nishino, Masahiro and Ogawa, Hiroyuki and Hirasawa, Naoyuki
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, ISSN 1633-8065, 08/2019
Although soft tissue tension during total knee arthroplasty (TKA) has been targeted to achieve equal flexion and extension gaps, such a perfect gap is not... 
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15. Full Text Remaining mild varus limb alignment leads to better clinical outcome in total knee arthroplasty for varus osteoarthritis
by Nishida, Kyohei and Nishida, Kyohei and Matsumoto, Tomoyuki and Matsumoto, Tomoyuki and Takayama, Koji and Takayama, Koji and Ishida, Kazunari and Ishida, Kazunari and Nakano, Naoki and Nakano, Naoki and Matsushita, Takehiko and Matsushita, Takehiko and Kuroda, Ryosuke and Kuroda, Ryosuke and Kurosaka, Masahiro and Kurosaka, Masahiro
Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, 11/2017, Volume 25, Issue 11, pp. 3488 - 3494
Postoperative neutral limb alignment [femorotibial mechanical axis (FTMA) 180° ± 3°] is generally considered to be one of the prerequisites for successful... 
Valgus alignment | Clinical outcome | Total knee arthroplasty | Medicine & Public Health | Orthopedics | Coronal alignment | Mild varus alignment | SURVIVAL | SYSTEM | SURGERY | SPORT SCIENCES | COMPONENTS | FOLLOW-UP | MECHANICAL AXIS ALIGNMENT | FAILURE | REPLACEMENT | ORTHOPEDICS | PROSTHESIS | Bone Malalignment - physiopathology | Arthroplasty, Replacement, Knee - adverse effects | Knee Prosthesis | Humans | Middle Aged | Knee Joint - diagnostic imaging | Male | Osteoarthritis, Knee - diagnostic imaging | Bone Malalignment - diagnostic imaging | Knee Joint - surgery | Bone Malalignment - etiology | Arthroplasty, Replacement, Knee - methods | Female | Aged | Osteoarthritis, Knee - physiopathology | Osteoarthritis, Knee - surgery | Medicine, Experimental | Medical research | Osteoarthritis | Patient outcomes | Knee | Surgical implants | Alignment | Statistical analysis | Arthroplasty (knee) | Biocompatibility | Arthritis | Knee (anatomy) | Joint surgery | Patients
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