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2012, Methods in molecular biology, ISBN 9781617793370, Volume 795.
Web Resource
2012, Methods in molecular biology, ISBN 1617793361, Volume 795., xi, 256
Book
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e39424 - e39424
Journal Article
Nature Biotechnology, ISSN 1087-0156, 02/2007, Volume 25, Issue 1, pp. 125 - 131
Mass spectrometry-based quantitative proteomics has become an important component of biological and clinical research. Although such analyses typically assume... 
Sequence Analysis, Protein - methods | Algorithms | Peptides - chemistry | Gene Expression Profiling - methods | Peptide Mapping - methods | Proteome - analysis | Proteome - chemistry | Mass Spectrometry - methods | Peptides - analysis | Biotechnology | Peptides | Spectrum analysis | Proteomics | Index Medicus
Journal Article
Journal of The American Society for Mass Spectrometry, ISSN 1044-0305, 8/2014, Volume 25, Issue 8, pp. 1489 - 1497
We describe the design, preparation, and mass-spectrometric characterization of a new recombinant peptide calibration standard with uniform biophysical and... 
Biotechnology | Chemistry | Analytical Chemistry | Trypsin | Recombinant polypeptide | Electrospray ionization | Proteomics | Protease cleavage | Bioinformatics | Organic Chemistry | PASylation | CHEMISTRY, ANALYTICAL | FUSION | MALDI | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, PHYSICAL | SYNTHETIC-POLYMERS | PLASMA HALF-LIFE | SPECTROSCOPY | MULTIPLEXED ABSOLUTE QUANTIFICATION | CONCATENATED SIGNATURE PEPTIDES | PROTEINS | EXPRESSION | VECTORS | ELECTROSPRAY-IONIZATION | Molecular Weight | Recombinant Proteins - analysis | Peptides - genetics | Recombinant Fusion Proteins - analysis | Recombinant Fusion Proteins - metabolism | Reference Standards | Peptides - metabolism | Spectrometry, Mass, Electrospray Ionization | Proteolysis | Protein Engineering | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Peptide Fragments - genetics | Recombinant Proteins - metabolism | Endopeptidases - metabolism | Peptide Fragments - metabolism | Peptides - chemistry | Recombinant Proteins - chemistry | Calibration | Recombinant Fusion Proteins - chemistry | Trypsin - metabolism | Amino Acid Motifs | Peptide Fragments - analysis | Peptide Fragments - chemistry | Endopeptidases - genetics | Hydrophobic and Hydrophilic Interactions | Protein Conformation | Peptides - analysis | Ubiquitin | Peptides | Proteases | Analysis | Escherichia coli | Mass spectrometry | Standards | Spectroscopy | Polypeptides | Fragments | Amino acids | Ions | Ionization | Design standards | Cleavage | Scientific imaging | Recombinant | Cassettes | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2017, Volume 292, Issue 9, pp. 3854 - 3865
Journal Article
Science, ISSN 0036-8075, 12/2017, Volume 358, Issue 6367, p. eaan4368
Kinase inhibitors are important cancer therapeutics. Polypharmacology is commonly observed, requiring thorough target deconvolution to understand drug... 
REFINEMENT | PROTEIN | CHEMICAL PROTEOMICS | INHIBITOR SELECTIVITY | DATA QUALITY | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | INTEGRATIVE GENOMICS VIEWER | SALT-INDUCIBLE KINASES | CANCER | COMPREHENSIVE ANALYSIS | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Lung Neoplasms - drug therapy | Lung Neoplasms - enzymology | Cytokines - metabolism | Humans | Drug Discovery - methods | Antineoplastic Agents - chemistry | Molecular Targeted Therapy | Xenograft Model Antitumor Assays | Leukemia, Myeloid, Acute - enzymology | Protein Kinase Inhibitors - chemistry | Animals | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myeloid, Acute - drug therapy | Antineoplastic Agents - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Proteomics - methods | Salts | Target recognition | Lung cancer | Selectivity | Drug development | Cancer therapies | Signal transduction | Biomolecules | Protein-tyrosine kinase | Tyrosine | Medical research | Imatinib | Decision making | Medical treatment | Mass spectroscopy | Tumor necrosis factor-α | Embryos | Bruton's tyrosine kinase | Mode of action | Side effects | Inhibitors | Interleukin 10 | Affinity | Drug discovery | Mass spectrometry | Acute myeloid leukemia | Drugs | Deregulation | Leukemia | Interleukin | Medical services | Clinical trials | Leucine | Kinases | Biological effects | Epidermal growth factor | Salt-inducible kinase | Xenografts | Cell survival | Epidermal growth factor receptors | Research & development--R&D | Therapeutic applications | Myeloid leukemia | Markers | Data processing | Lead compounds | Leucine zipper proteins | Signaling | Proteomics | Cancer | Index Medicus
Journal Article