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SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 9
Previous studies have shown that an intronic variant rs780094 of the GCKR gene (glucokinase regulatory protein) is significantly associated with several... 
HYPERGLYCEMIA | METABOLISM | COMMON VARIANT | ACIDS | FATTY LIVER-DISEASE | MULTIDISCIPLINARY SCIENCES | RISK | SECRETION | GLUCOKINASE | INSULIN SENSITIVITY | GLUCOSE-TOLERANCE | Metabolomics | Statistical analysis | Threonine | Serine | Tryptophan | Mass spectroscopy | Lipids | Population studies | Sphingolipids | Genetic variance | Vitamin A | Pleiotropy | Metabolites | Glucokinase | Alleles | Lipid metabolism | Sulfate
Journal Article
by Fuchsberger, Christian and Flannick, Jason and Teslovich, Tanya M and Mahajan, Anubha and Agarwala, Vineeta and Gaulton, Kyle J and Ma, Clement and Fontanillas, Pierre and Moutsianas, Loukas and McCarthy, Davis J and Rivas, Manuel A and Perry, John R. B and Sim, Xueling and Blackwell, Thomas W and Robertson, Neil R and Rayner, N. William and Cingolani, Pablo and Locke, Adam E and Fernandez Tajes, Juan and Highland, Heather M and Dupuis, Josee and Chines, Peter S and Lindgren, Cecilia M and Hartl, Christopher and Jackson, Anne U and Chen, Han and Huyghe, Jeroen R and van de Bunt, Martijn and Pearson, Richard D and Kumar, Ashish and Müller-Nurasyid, Martina and Grarup, Niels and Stringham, Heather M and Gamazon, Eric R and Lee, Jaehoon and Chen, Yuhui and Scott, Robert A and Below, Jennifer E and Chen, Peng and Huang, Jinyan and Go, Min Jin and Stitzel, Michael L and Pasko, Dorota and Parker, Stephen C. J and Varga, Tibor V and Green, Todd and Beer, Nicola L and Day-Williams, Aaron G and Ferreira, Teresa and Fingerlin, Tasha and Horikoshi, Momoko and Hu, Cheng and Huh, Iksoo and Ikram, Mohammad Kamran and Kim, Bong-Jo and Kim, Yongkang and Kim, Young Jin and Kwon, Min-Seok and Lee, Juyoung and Lee, Selyeong and Lin, Keng-Han and Maxwell, Taylor J and Nagai, Yoshihiko and Wang, Xu and Welch, Ryan P and Yoon, Joon and Zhang, Weihua and Barzilai, Nir and Voight, Benjamin F and Han, Bok-Ghee and Jenkinson, Christopher P and Kuulasmaa, Teemu and Kuusisto, Johanna and Manning, Alisa and Ng, Maggie C. Y and Palmer, Nicholette D and Balkau, Beverley and Stancáková, Alena and Abboud, Hanna E and Boeing, Heiner and Gieaitis, Vilmantas and Prabhakaran, Dorairaj and Gottesman, Omri and Scott, James and Carey, Jason and Kwan, Phoenix and Grant, George and Smith, Joshua D and Neale, Benjamin M and Purcell, Shaun and Butterworth, Adam S and Howson, Joanna M. M and Lee, Heung Man and Lu, Yingchang and Kwak, Soo-Heon and Zhao, Wei and Danesh, John and Lam, Vincent K. L and Park, Kyong Soo and Saleheen, Danish and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2016, Volume 536, Issue 7614, pp. 41 - +
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2017, Volume 58, Issue 3, pp. 481 - 493
The Metabolic Syndrome in Men (METSIM) study is a population-based study including 10,197 Finnish men examined in 2005-2010. The aim of the study is to... 
Metabolic disease | Type 2 diabetes | Metsim | Cardiovascular risk factors | Coronary artery disease | coronary artery disease | TYPE-2 DIABETES SUSCEPTIBILITY | COMMON VARIANTS | METSIM | FASTING GLUCOSE-LEVELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE DIVERSITY PANEL | GENETIC ARCHITECTURE | cardiovascular risk factors | metabolic disease | INSULIN SENSITIVITY | BLOOD-PRESSURE | type 2 diabetes | BODY-MASS INDEX | NONDIABETIC FINNISH MEN | GENOME-WIDE ASSOCIATION | Metabolomics | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Cardiovascular Diseases - pathology | Cardiovascular Diseases - genetics | Hyperglycemia - genetics | Diabetes Mellitus, Type 2 - epidemiology | Adipose Tissue - metabolism | Metabolic Syndrome - blood | Hyperglycemia - pathology | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Metabolic Syndrome - epidemiology | Genetic Predisposition to Disease | Glucose Tolerance Test | Genetic Association Studies | Risk Factors | Adipose Tissue - pathology | Blood Glucose | Genotype | Diabetes Mellitus, Type 2 - blood | Hyperglycemia - blood | Biopsy | Metabolic Syndrome - genetics | Aged | High-Throughput Nucleotide Sequencing | Polymorphism, Single Nucleotide | Diabetes Mellitus, Type 2 - pathology | Metabolic Syndrome - pathology | Genome, Human | Adipose tissue | Nuclear magnetic resonance--NMR | Transcription | Diabetes mellitus | Population studies | Genomes | Metabolic syndrome | Risk factors | Glucose tolerance | Hyperglycemia | Genotyping | Metabolites | Phenotyping | Diabetes | Genetic factors | Cardiovascular diseases | Health risk assessment | Metabolic disorders | Index Medicus | Special Report
Journal Article
Journal Article
Journal Article
Journal Article
by Lu, Yingchang and Day, Felix R and Gustafsson, Stefan and Buchkovich, Martin L and Na, Jianbo and Bataille, Veronique and Cousminer, Diana L and Dastani, Zari and ng, Alexander W and Esko, Tõnu and Evans, David M and Falchi, Mario and Feitosa, Mary F and Ferreira, Teresa and Hedman, Åsa K and Haring, Robin and Hysi, Pirro G and Iles, Mark M and Justice, Anne E and Kanoni, Stavroula and Lagou, Vasiliki and Li, Rui and Li, Xin and Locke, Adam and Lu, Chen and Mägi, Reedik and Perry, John R. B and Pers, Tune H and Qi, Qibin and Sanna, Marianna and Schmidt, Ellen M and Scott, William R and Shungin, Dmitry and Teumer, Alexander and Vinkhuyzen, Anna A. E and Walker, Ryan W and Westra, Harm-Jan and Zhang, Mingfeng and Zhang, Weihua and Zhao, Jing Hua and Zhu, Zhihong and Afzal, Uzma and Ahluwalia, Tarunveer Singh and Bakker, Stephan J. L and Bellis, Claire and Bonnefond, Amélie and Borodulin, Katja and Buchman, Aron S and Cederholm, Tommy and Choh, Auey C and Choi, Hyung Jin and Curran, Joanne E and de Groot, Lisette C. P. G. M and de Jager, Philip L and Dhonukshe-Rutten, Rosalie A. M and Enneman, Anke W and Eury, Elodie and Evans, Daniel S and Forsen, Tom and Frieich, Nele and Fumeron, Frédéric and Garcia, Melissa E and Gärtner, Simone and Han, Bok-Ghee and Havulinna, Aki S and Hayward, Caroline and Hernandez, Dena and Hillege, Hans and Ittermann, Till and Kent, Jack W and Kolcic, Ivana and Laatikainen, Tiina and Lahti, Jari and Mateo Leach, Irene and Lee, Christine G and Lee, Jong-Young and Liu, Tian and Liu, Youfang and Lobbens, Stéphane and Loh, Marie and Lyytikäinen, Leo-Pekka and Medina-Gomez, Carolina and Michaëlsson, Karl and Nalls, Mike A and Nielson, Carrie M and Oozageer, Laticia and Pascoe, Laura and Paternoster, Lavinia and Polašek, Ozren and Ripatti, Samuli and Sarzynski, Mark A and Shin, Chan Soo and Narančić, Nina Smolej and Spira, Dominik and Srikanth, Priya and Steinhagen-Thiessen, Elisabeth and Sung, Yun Ju and Swart, Karin M. A and Taittonen, Leena and Tanaka, Toshiko and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Institutionen för odontologi and Umeå universitet and Medicin
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, pp. 10495 - 10495
Journal Article
by Strawbridge, Rona J and Dupuis, Josée and Prokopenko, Inga and Barker, Adam and Ahlqvist, Emma and Rybin, Denis and Petrie, John R and Travers, Mary E and Bouatia-Naji, Nabila and Dimas, Antigone S and Nica, Alexana and Wheeler, Eleanor and Chen, Han and Voight, Benjamin F and Taneera, Jalal and Kanoni, Stavroula and Peden, John F and Turrini, Fabiola and Gustafsson, Stefan and Zabena, Carina and Almgren, Peter and Barker, David J. P and Barnes, Daniel and Dennison, Elaine M and Eriksson, Johan G and Eriksson, Per and Eury, Elodie and Folkersen, Lasse and Fox, Caroline S and Frayling, Timothy M and Goel, Anuj and Gu, Harvest F and Horikoshi, Momoko and Isomaa, Bo and Jackson, Anne U and Jameson, Karen A and Kajantie, Eero and Kerr-Conte, Julie and Kuulasmaa, Teemu and Kuusisto, Johanna and Loos, Ruth J. F and Luan, Jian'an and Makrilakis, Konstantinos and Manning, Alisa K and Martínez-Larrad, María Teresa and Narisu, Narisu and Nastase Mannila, Maria and Ohrvik, John and Osmond, Clive and Pascoe, Laura and Payne, Felicity and Sayer, Avan A and Sennblad, Bengt and Silveira, Angela and Stancáková, Alena and Stirrups, Kathy and Swift, Amy J and Syvänen, Ann-Christine and Tuomi, Tiinamaija and van 't Hooft, Ferdinand M and Walker, Mark and Weedon, Michael N and Xie, Weijia and Zethelius, Björn and Ongen, Halit and Mälarstig, Anders and Hopewell, Jemma C and Saleheen, Danish and Chambers, John and Parish, Sarah and Danesh, John and Kooner, Jaspal and Ostenson, Claes-Göran and Lind, Lars and Cooper, Cyrus C and Serrano-Ríos, Manuel and Ferrannini, Ele and Forsen, Tom J and Clarke, Robert and Franzosi, Maria Grazia and Seedorf, Udo and Watkins, Hugh and Froguel, Philippe and Johnson, Paul and Deloukas, Panos and Collins, Francis S and Laakso, Markku and Dermitzakis, Emmanouil T and Boehnke, Michael and McCarthy, Mark I and Wareham, Nicholas J and Groop, Leif and Pattou, François and Gloyn, Anna L and Dedoussis, George V and Lyssenko, Valeriya and Meigs, James B and Barroso, Inês and Watanabe, Richard M and Ingelsson, Erik and ... and C4D Consortium and DIAGRAM Consortium and GIANT Consortium and CARDIoGRAM Consortium and MuTHER Consortium and the MuTHER Consortium and the CARDIoGRAM Consortium and the C4D Consortium and the DIAGRAM Consortium and the GIANT Consortium and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Geriatrik and Uppsala universitet and Institutionen för medicinska vetenskaper and Institutionen för folkhälso- och vårdvetenskap
Diabetes, ISSN 0012-1797, 2011, Volume 60, Issue 10, pp. 2624 - 2634
Journal Article