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1. Full Text Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study
by To, Kelvin Kai-Wang and Tsang, Owen Tak-Yin and Leung, Wai-Shing and Tam, Anthony Raymond and Wu, Tak-Chiu and Lung, David Christopher and Yip, Cyril Chik-Yan and Cai, Jian-Piao and Chan, Jacky Man-Chun and Chik, Thomas Shiu-Hong and Lau, Daphne Pui-Ling and Choi, Chris Yau-Chung and Chen, Lin-Lei and Chan, Wan-Mui and Chan, Kwok-Hung and Ip, Jonathan Daniel and Ng, Anthony Chin-Ki and Poon, Rosana Wing-Shan and Luo, Cui-Ting and Cheng, Vincent Chi-Chung and Chan, Jasper Fuk-Woo and Hung, Ivan Fan-Ngai and Chen, Zhiwei and Chen, Honglin and Yuen, Kwok-Yung
The Lancet infectious diseases, ISSN 1473-3099, 05/2020, Volume 20, Issue 5, pp. 565 - 574
Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Severity of Illness Index | Pandemics | Betacoronavirus - isolation & purification | COVID-19 Testing | Clinical Laboratory Techniques | Coronavirus Infections - diagnosis | Humans | Middle Aged | Male | Antibodies, Viral - blood | Coronavirus Infections - immunology | Pneumonia, Viral - immunology | Viral Load | Betacoronavirus - immunology | COVID-19 | Saliva - virology | SARS-CoV-2 | Coronavirus Infections - virology | Pneumonia, Viral - diagnosis | Adult | Female | Aged | Betacoronavirus - genetics | Pneumonia, Viral - virology | Viral antibodies | Epidemics | Analysis | Severe acute respiratory syndrome | Genomics | Antibodies | Coronaviruses | Health aspects | Protein binding | Health care | Immunoglobulin M | Nosocomial infection | RNA-directed DNA polymerase | Immunoglobulin G | Viral diseases | Viruses | Genomes | Infections | Middle East respiratory syndrome | Gene sequencing | Throats | Antiretroviral drugs | Antiviral agents | Spike protein | Health risks | Ribonucleic acid--RNA | Patients | Severe acute respiratory syndrome coronavirus 2 | Studies | Hospitals | Consultancy services | Respiratory diseases | Rectum | Mutation | Saliva | Index Medicus
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2. Full Text A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
by Chan, Jasper Fuk-Woo and Yuan, Shuofeng and Kok, Kin-Hang and To, Kelvin Kai-Wang and Chu, Hin and Yang, Jin and Xing, Fanfan and Liu, Jieling and Yip, Cyril Chik-Yan and Poon, Rosana Wing-Shan and Tsoi, Hoi-Wah and Lo, Simon Kam-Fai and Chan, Kwok-Hung and Poon, Vincent Kwok-Man and Chan, Wan-Mui and Ip, Jonathan Daniel and Cai, Jian-Piao and Cheng, Vincent Chi-Chung and Chen, Honglin and Hui, Christopher Kim-Ming and Yuen, Kwok-Yung
The Lancet (British edition), ISSN 0140-6736, 02/2020, Volume 395, Issue 10223, pp. 514 - 523
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Genome, Viral | COVID-19 Testing | Clinical Laboratory Techniques | Coronavirus Infections - diagnosis | Humans | Middle Aged | Family Health | Tomography, X-Ray Computed | China - epidemiology | Phylogeny | Whole Genome Sequencing - methods | Betacoronavirus - classification | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | SARS-CoV-2 | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Pneumonia, Viral - diagnosis | Adult | Aged | Radiography, Thoracic | Betacoronavirus - genetics | Medical research | Bats | Pneumonia | Bacterial pneumonia | Genomics | Medicine, Experimental | Coronaviruses | Nucleotide sequencing | Epidemiology | DNA sequencing | Nosocomial infection | C-reactive protein | Microbiology | Laboratories | Glass | Viruses | Genomes | Asymptomatic | DNA-directed RNA polymerase | Gene sequencing | Proteins | Respiratory tract | Next-generation sequencing | Genetic analysis | Clusters | Phylogenetics | Bioinformatics | Thrombocytopenia | Urine | Spike protein | Diarrhea | Lactate dehydrogenase | RNA polymerase | Ribonucleic acid--RNA | Patients | Pharynx | RNA-directed RNA polymerase | Fever | L-Lactate dehydrogenase | Polymerase chain reaction | Travel | Animals | Respiratory syncytial virus | Hospitals | Disease transmission | Lungs | Lymphopenia | Travellers | Respiratory diseases | Influenza | Lactic acid | Index Medicus | Abridged Index Medicus
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3. Full Text Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs
by Chan, Jasper Fuk-Woo and Yip, Cyril Chik-Yan and Tsang, Jessica Oi-Ling and Tee, Kah-Meng and Cai, Jian-Piao and Chik, Kenn Ka-Heng and Zhu, Zheng and Chan, Chris Chung-Sing and Choi, Garnet Kwan-Yue and Sridhar, Siddharth and Zhang, Anna Jinxia and Lu, Gang and Chiu, Kin and Lo, Amy Cheuk-Yin and Tsao, Sai-Wah and Kok, Kin-Hang and Jin, Dong-Yan and Chan, Kwok-Hung and Yuen, Kwok-Yung
Emerging microbes & infections, ISSN 2222-1751, 08/2016, Volume 5, Issue 1, pp. e93 - 12
Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Zika Virus - genetics | Humans | Cercopithecus aethiops | Viral Load | Zika Virus Infection - virology | Swine | Primates | Female | Disease Reservoirs | Viral Tropism | Vero Cells | Zika Virus - pathogenicity | Caco-2 Cells | Cell Line | Rabbits | Cricetinae | Zika Virus - growth & development | Disease Susceptibility | Zika Virus - physiology | Mosquito Vectors - virology | Dengue Virus - growth & development | Pregnancy | Zika Virus Infection - transmission | Animals | Virus Replication | Cell Line, Tumor | Dengue Virus - physiology | Viral Nonstructural Proteins - metabolism | Index Medicus | transmission | tropism | animal | placenta | Original | cell line | virus | flavivirus | Zika
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4. Full Text Infection of bat and human intestinal organoids by SARS-CoV-2
by Zhou Jie and Li Cun and Liu Xiaojuan and Chiu Man Chun and Zhao Xiaoyu and Wang Dong and Wei Yuxuan and Lee, Andrew and Zhang, Anna Jinxia and Chu Hin and Cai Jian-Piao and Yip, Cyril Chik-Yan and Chan, Ivy Hau-Yee and Wong, Kenneth Kak-Yuen and Tsang, Owen Tak-Yin and Chan Kwok-Hung and Chan, Jasper Fuk-Woo and To, Kelvin Kai-Wang and Chen Honglin and Yuen, Kwok Yung
Nature medicine, ISSN 1078-8956, 07/2020, Volume 26, Issue 7, pp. 1077 - 1083
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Betacoronavirus - pathogenicity | Chiroptera - virology | Pandemics | Humans | Child, Preschool | Enterocytes - virology | Infant | Male | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | SARS-CoV-2 | Intestines - virology | Female | Cell Differentiation | Enterocytes - pathology | Vero Cells | Viral Tropism - physiology | Chlorocebus aethiops | Intestines - pathology | Organoids - pathology | Pneumonia, Viral - pathology | Cells, Cultured | Intestinal Mucosa - virology | Reverse Transcriptase Polymerase Chain Reaction | Viral Load - genetics | Animals | Coronavirus Infections - virology | Coronavirus Infections - pathology | Viral Load - methods | Pneumonia, Viral - virology | Enterocytes - physiology | Intestinal Mucosa - pathology | Organoids - virology | Bats | Intestines | Disease transmission | Physiological aspects | Models | Coronaviruses | Health aspects | Methods | Genomics | Analysis | Severe acute respiratory syndrome | Resveratrol | Genomes | Cell culture | Gastrointestinal symptoms | Nucleotide sequence | Viral diseases | Diarrhea | Viruses | Homology | Infections | Ribonucleic acid--RNA | Epithelium | Severe acute respiratory syndrome coronavirus 2 | Organoids | Intestine | Life cycle analysis | Respiratory diseases | Replication | Robustness | Index Medicus
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5. Full Text Convalescent Plasma Treatment Reduced Mortality in Patients With Severe Pandemic Influenza A (H1N1) 2009 Virus Infection
by Ivan FN Hung and Kelvin KW To and Cheuk-Kwong Lee and Kar-Lung Lee and Kenny Chan and Wing-Wah Yan and Raymond Liu and Chi-Leung Watt and Wai-Ming Chan and Kang-Yiu Lai and Chi-Kwan Koo and Tom Buckley and Fu-Loi Chow and Kwan-Keung Wong and Hok-Sum Chan and Chi-Keung Ching and Bone SF Tang and Candy CY Lau and Iris WS Li and Shao-Haei Liu and Kwok-Hung Chan and Che-Kit Lin and Chi-Kit Lin and Kwok-Yung Yuen
Clinical infectious diseases, ISSN 1058-4838, 2/2011, Volume 52, Issue 4, pp. 447 - 456
H1N1 subtype influenza A virus | Intensive care units | State hospitals | Pandemics | Mortality | Viruses | Hospital units | Infections | ARTICLES AND COMMENTARIES | Viral load | Blood plasma | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Medical sciences | Human viral diseases | Viral diseases | Influenza A Virus, H1N1 Subtype - immunology | Immunotherapy - methods | Prospective Studies | Humans | Middle Aged | Plasma - immunology | Influenza A Virus, H1N1 Subtype - pathogenicity | Male | Treatment Outcome | Antibodies, Viral - blood | Viral Load | Influenza A Virus, H1N1 Subtype - isolation & purification | Survival Analysis | Influenza, Human - mortality | Adult | Female | Influenza, Human - virology | Influenza, Human - therapy | Antibodies, Neutralizing - blood | Cohort Studies | Cytokines - blood | Epidemics | Control | Care and treatment | Usage | United States | Patient outcomes | Swine influenza | Health aspects | Intensive care | Kidney diseases | Cytokines | Swine flu | Patients | Index Medicus | and Commentaries
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6. Full Text Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial
by Hung, Ivan Fan-Ngai, MD and Zhang, Anna Jinxia, PhD and To, Kelvin Kai-Wang, MD and Chan, Jasper Fuk-Woo, MBBS and Li, Patrick, MSc and Wong, Tin-Lun, BSc and Zhang, Ricky, MSc and Chan, Tuen-Ching, MD and Chan, Brian Chun-Yuan, BSc and Wai, Harrison Ho and Chan, Lok-Wun and Fong, Hugo Pak-Yiu and Hui, Raymond Kar-Ching and Kong, Ka-Lun and Leung, Arthur Chun-Fung, MBiochem and Ngan, Abe Ho-Ting and Tsang, Louise Wing-Ki and Yeung, Alex Pat-Chung and Yiu, Geo Chi-Ngo and Yung, Wing and Lau, Johnson Y-N, MD and Chen, Honglin, PhD and Chan, Kwok-Hung, PhD and Yuen, Kwok-Yung, Prof
The Lancet infectious diseases, ISSN 1473-3099, 2016, Volume 16, Issue 2, pp. 209 - 218
Infectious Disease | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Influenza A Virus, H1N1 Subtype - immunology | Influenza Vaccines - administration & dosage | Adjuvants, Immunologic - administration & dosage | Double-Blind Method | Hong Kong | Influenza A Virus, H3N2 Subtype - drug effects | Humans | Aminoquinolines - administration & dosage | Male | Influenza A Virus, H1N1 Subtype - drug effects | Influenza A Virus, H3N2 Subtype - immunology | Young Adult | Adolescent | Adult | Female | Administration, Topical | Influenza, Human - prevention & control | Influenza, Human - immunology | Injections, Intradermal | Influenza vaccines | Clinical trials | Product development | Influenza | Vaccination | Epidemics | Pain | Swine flu | Colleges & universities | Viruses | Skin | Vaccines | Chronic illnesses | Index Medicus
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7. Full Text Homozygous L-SIGN ( CLEC4M ) plays a protective role in SARS coronavirus infection
by Chan, Kwok-Hung and Chan, Li-Chong and Screaton, Gavin and Zheng, Bojian and Austyn, Jonathan M and Chan, Vera S F and Poon, Leo L M and Ngan, Hextan Y S and Cheung, Annie N Y and Mak, William and Lin, Chen-Lung S and Khoo, Ui-Soon and Chan, Kelvin Y K and Chen, Yongxiong and Yip, Shea-Ping and Tam, Paul K H and Peiris, Malik and Xu, Xiaoning
Nature genetics, ISSN 1061-4036, 01/2006, Volume 38, Issue 1, pp. 38 - 46
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Cell Adhesion Molecules - genetics | Severe Acute Respiratory Syndrome - epidemiology | Vero Cells - virology | Cricetulus | Humans | Molecular Sequence Data | Tandem Repeat Sequences | Lectins, C-Type - genetics | Intestine, Small - physiology | SARS Virus - metabolism | Lectins, C-Type - metabolism | Lung - virology | CHO Cells - virology | Cricetinae | Genetic Predisposition to Disease | Chlorocebus aethiops | Receptors, Cell Surface - metabolism | Lung - physiology | Cell Adhesion Molecules - metabolism | SARS Virus - pathogenicity | Homozygote | Animals | Hong Kong - epidemiology | Severe Acute Respiratory Syndrome - genetics | Proteasome Endopeptidase Complex - metabolism | Cohort Studies | Receptors, Cell Surface - genetics | Polymerase chain reaction | Usage | Severe acute respiratory syndrome | Glycoproteins | Genetic aspects | Research | Diagnosis | Health aspects | Risk factors | Index Medicus
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8. Full Text Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
by Hung, Ivan Fan-Ngai and Lung, Kwok-Cheung and Tso, Eugene Yuk-Keung and Liu, Raymond and Chung, Tom Wai-Hin and Chu, Man-Yee and Ng, Yuk-Yung and Lo, Jenny and Chan, Jacky and Tam, Anthony Raymond and Shum, Hoi-Ping and Chan, Veronica and Wu, Alan Ka-Lun and Sin, Kit-Man and Leung, Wai-Shing and Law, Wai-Lam and Lung, David Christopher and Sin, Simon and Yeung, Pauline and Yip, Cyril Chik-Yan and Zhang, Ricky Ruiqi and Fung, Agnes Yim-Fong and Yan, Erica Yuen-Wing and Leung, Kit-Hang and Ip, Jonathan Daniel and Chu, Allen Wing-Ho and Chan, Wan-Mui and Ng, Anthony Chin-Ki and Lee, Rodney and Fung, Kitty and Yeung, Alwin and Wu, Tak-Chiu and Chan, Johnny Wai-Man and Yan, Wing-Wah and Chan, Wai-Ming and Chan, Jasper Fuk-Woo and Lie, Albert Kwok-Wai and Tsang, Owen Tak-Yin and Cheng, Vincent Chi-Chung and Que, Tak-Lun and Lau, Chak-Sing and Chan, Kwok-Hung and To, Kelvin Kai-Wang and Yuen, Kwok-Yung
The Lancet (British edition), ISSN 0140-6736, 05/2020, Volume 395, Issue 10238, pp. 1695 - 1704
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antiviral agents | Product development | Biological response modifiers | Lopinavir | Viral antigens | Interferon beta | Therapy | Pandemics | Laboratories | Ritonavir | Health services | Viral diseases | Population studies | Infections | Middle East respiratory syndrome | Ribavirin | COVID-19 | Hepatitis | Randomization | Drug dosages | Signs and symptoms | Bacterial infections | Cytokines | Severe acute respiratory syndrome | Diarrhea | Nausea | Coronaviruses | Patients | Severe acute respiratory syndrome coronavirus 2 | Polymerase chain reaction | Influenza | Respiratory diseases | Interferon | Mutation | Index Medicus | Abridged Index Medicus
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