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41. Full Text Role of Laparoscopic Surgery for Treatment of Early Colorectal Carcinoma
by Fazio, Victor W and Fazio, Victor W and López-Kostner, Francisco and López-Kostner, Francisco
World Journal of Surgery, ISSN 0364-2313, 9/2000, Volume 24, Issue 9, pp. 1056 - 1060
The first laparoscopic colorectal surgery was performed in 1991. Several reports have showed some advantages for the laparoscopic technique compared to open... 
Medicine & Public Health | Cardiac Surgery | Surgery | Abdominal Surgery | Vascular Surgery | Thoracic Surgery | General Surgery | COLECTOMY | SURGERY | LEARNING-CURVE | MURINE MODEL | METASTASES FOLLOWING LAPAROSCOPY | ASSISTED COLON RESECTION | ABDOMINAL-WALL RECURRENCE | WOUND RECURRENCE | CANCER-SURGERY | ADJUVANT THERAPY | SUBCUTANEOUS METASTASES | Colorectal Neoplasms - surgery | Animals | Neoplasm Seeding | Humans | Abdominal Muscles - pathology | Colectomy - methods | Treatment Outcome | Laparoscopy | Patient Selection | Laparoscopic surgery | Care and treatment | Drug therapy | Colorectal cancer | Cancer
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42. Full Text Impacto de las filtraciones anastomóticas en cirugía colorrectal
by López-Köstner, Francisco and Cerda C, Cesar and Wainstein G, Claudio and Kronberg, Udo and Larach K, Andrés and Larach S, Jorge and Zarate, Alejandro J and Castro A, Lorna
Revista Chilena de Cirugía, ISSN 0379-3893, 11/2016, Volume 68, Issue 6, pp. 417 - 421
La filtración de anastomosis es una de las complicaciones de mayor impacto en cirugía colorrectal. Analizar la frecuencia e impacto de las filtraciones... 
Morbilidad | Anastomosis leak | Morbility | Filtración anastomosis | Cirugía colorrectal | Colorectal surgery
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43. Full Text A Pilot Trial to Quantify Plasma Exosomes in Colorectal Cancer Screening from the International Collaborative Study between Chile and Japan
by Kobayashi, Maki and Kawachi, Hiroshi and Hurtado, Claudia and Wielandt, Ana María and Ponce, Alejandra and Karelovic, Stanko and Pasternak, Samara and Delgado, Carlos and Pinto, Pablo and Carrasco, Hernan and Ito, Takashi and Okada, Takuya and Tanaka, Koji and Odagaki, Tomoyuki and Zárate, Alejandro José and Kronberg, Udo and López-Köstner, Francisco and Tsubaki, Masahiro and Kawano, Tatsuyuki and Eishi, Yoshinobu
Digestion, ISSN 0012-2823, 11/2018, Volume 98, Issue 4, pp. 270 - 274
Background: In Chile, a national colorectal cancer (CRC) screening program using immunochemical fecal occult blood tests and colonoscopy was started in 2012 as... 
Short Communication | Screening | Colorectal adenoma | Plasma exosomes | Immunochemical fecal occult blood test | Colorectal cancer | RATES | FECAL OCCULT BLOOD | GASTROENTEROLOGY & HEPATOLOGY | Adenoma - diagnosis | Adenocarcinoma - pathology | Early Detection of Cancer - methods | Colon - pathology | Colorectal Neoplasms - blood | Adenocarcinoma - blood | Humans | Japan | Middle Aged | Male | International Cooperation | Exosomes | Colorectal Neoplasms - diagnosis | Adenocarcinoma - diagnosis | Adenoma - blood | Colon - diagnostic imaging | Pilot Projects | Colonoscopy | Adenoma - pathology | Female | Aged | Occult Blood | Chile | Colorectal Neoplasms - pathology
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44. Full Text Lynch syndrome in South America: past, present and future
by Vaccaro, Carlos A and Sarroca, Carlos and Rossi, Benedito and Lopez-Kostner, Francisco and Dominguez, Mev and Calo, Natalia Causada and Cutait, Raul and Valle, Adriana Della and Nuñez, Lina and Neffa, Florencia and Alvarez, Karin and Gonzalez, Maria Laura and Kalfayan, Pablo and Lynch, Henry T and Church, James
Familial Cancer, ISSN 1389-9600, 7/2016, Volume 15, Issue 3, pp. 437 - 445
After decades of unawareness about Lynch syndrome, the medical community in South America is increasingly interested and informed. The visits and support of... 
Human Genetics | Hereditary cancer registry | Biomedicine | Genetic counseling | Hereditary colorectal cancer | Cancer Research | Genetic testing | Epidemiology | Biomedicine general | Lynch syndrome | NONPOLYPOSIS COLORECTAL-CANCER | MSH2 MUTATIONS | HMLH1 | MLH1 | INDIVIDUALS | ONCOLOGY | FAMILIES | GENETICS & HEREDITY | SPECTRUM | CARCINOMA | Genetic Predisposition to Disease | South America - epidemiology | Genetic Testing | Genetic Counseling - statistics & numerical data | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Colorectal Neoplasms, Hereditary Nonpolyposis - epidemiology | Registries - statistics & numerical data | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Genetic Counseling - trends | Germ-Line Mutation | Colorectal cancer | Medical genetics
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45. Full Text Spectrum of MLH1 and MSH2 Mutations in Chilean Families With Suspected Lynch Syndrome
by Alvarez, Karin and Hurtado, Claudia and Hevia, Montserrat A and Wielandt, Ana Maria and de la Fuente, Marjorie and Church, James and Carvallo, Pilar and López-Köstner, Francisco
Diseases of the Colon & Rectum, ISSN 0012-3706, 04/2010, Volume 53, Issue 4, pp. 450 - 459
PURPOSE:Lynch syndrome is the most common inherited syndrome of colorectal cancer, caused principally by germline mutations in MLH1 and MSH2. We report our... 
Hereditary nonpolyposis colorectal cancer | MSH2 | Mismatch repair | Chilean population | Microsatellite instability | MLH1 | Lynch syndrome | SURGERY | HMSH2 | NONPOLYPOSIS COLORECTAL-CANCER | HMLH1 | BETHESDA GUIDELINES | GERMLINE MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | CARCINOMA | EXPRESSION | HNPCC FAMILIES | MutL Protein Homolog 1 | Genetic Predisposition to Disease | Microsatellite Instability | Genetic Testing | Polymorphism, Single-Stranded Conformational - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Middle Aged | Male | MutS Homolog 2 Protein - genetics | Reverse Transcriptase Polymerase Chain Reaction | Immunoenzyme Techniques | Phenotype | Base Sequence | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Germ-Line Mutation | Adult | Female | Registries | Aged | Chile | Nuclear Proteins - genetics
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46. Full Text Gene symbol: APC. Disease: Adenomatous polyposis coli
by Lopez-Kostner, Francisco
Human genetics, 2008, Volume 124, Issue 3, p. 316
Adenomatous Polyposis Coli Protein - genetics | Point Mutation | Humans | Codon - genetics | Codon, Nonsense | Adenomatous Polyposis Coli - genetics | Codon, Terminator | Amino Acid Substitution
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47. Full Text Mutational Screening of the APC Gene in Chilean Families with Familial Adenomatous Polyposis: Nine Novel Truncating Mutations
by De la Fuente, Marjorie K and Alvarez, Karin P and Letelier, Alejandro J and Bellolio, Felipe and Acuña, Mariana L and León, Francisca S and Pinto, Eliana and Carvallo, Pilar and López-Köstner, Francisco
Diseases of the Colon & Rectum, ISSN 0012-3706, 12/2007, Volume 50, Issue 12, pp. 2142 - 2148
Familial adenomatous polyposis is characterized by the development of hundreds of adenomatous polyps located mainly in the colon and rectum. Patients with... 
Medicine & Public Health | APC | Colorectal Surgery | Surgery | Familial adenomatous polyposis | Gastroenterology | Oncology | Chilean | Genotype-phenotype correlation | Surgical Oncology | SURGERY | genotype-phenotype correlation | RISK | IDENTIFICATION | TUMORS | COLON-CANCER | GERM-LINE MUTATIONS | FAP | COLORECTAL-CANCER | DNA | ASHKENAZI JEWS | CHROMOSOME-5 | familial adenomatous polyposis | GASTROENTEROLOGY & HEPATOLOGY | Genetic Predisposition to Disease | Prevalence | Humans | Adenomatous Polyposis Coli - epidemiology | Genetic Testing - methods | Polymorphism, Single-Stranded Conformational | Genes, APC - physiology | Adult | Family | DNA, Neoplasm - genetics | Mutation | Adenomatous Polyposis Coli - genetics | Child | Chile - epidemiology | Adenomatous Polyposis Coli - diagnosis | Genetic aspects | Polyposis, Familial | Gene mutations | Human genetics
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48. Full Text Prevalencia y características de mutaciones somáticas del gen KRAS en pacientes chilenos con cáncer colorrectal
by Hurtado, Claudia and Encina, Gonzalo and Wielandt, Ana María and Zárate, Alejandro José and Castro, Magdalena and Carrillo, Katya and Kronberg, Udo and López-Köstner, Francisco
Revista médica de Chile, ISSN 0034-9887, 11/2014, Volume 142, Issue 11, pp. 1407 - 1414
MEDICINE, GENERAL & INTERNAL
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49. Full Text Prevalencia y características de mutaciones somáticas del gen KRAS en pacientes chilenos con cáncer colorectal
by Hurtado, Claudia and Encina, Gonzalo and Wielandt, Ana María and Zárate, Alejandro José and Castro, Magdalena and Carrillo, Katya and Kronberg, Udo and López-Köstner, Francisco
Revista médica de Chile, ISSN 0034-9887, 11/2014, Volume 142, Issue 11, pp. 1407 - 1414
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50. Full Text Characterization of patients with sporadic colorectal cancer following the new Consensus Molecular Subtypes (CMS)
by Wielandt, AM and Villarroel, C and Hurtado, C and Simian, D and Zamorano, D and Martinez, M and Castro, M and Vial, MT and Kronberg, U and Lopez-Kostner, F
REVISTA MEDICA DE CHILE, ISSN 0034-9887, 04/2017, Volume 145, Issue 4, pp. 419 - 430
Background: Colorectal cancer (CRC) is an heterogeneous disease. Three carcinogenic pathways determine its molecular profile: microsatellite instability (MSI),... 
SURVIVAL | Microsatellite Instability | PROGNOSTIC IMPACT | CpG Island | CLASSIFICATION | CIN | BRAF | Carcinogenesis | ISLAND METHYLATOR PHENOTYPE | COLON-CANCER | MEDICINE, GENERAL & INTERNAL | DNA | MUTATION | Colorectal Neoplasms | Chromosomal Instability | Adenocarcinoma - pathology | Prospective Studies | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | DNA Methylation - genetics | Consensus | Phenotype | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | Aged | Biomarkers, Tumor - genetics | DNA, Neoplasm - genetics | Mutation | Chile | Colorectal Neoplasms - pathology
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51. Full Text Análisis molecular del cáncer de colon esporádico
by Hurtado, Claudia and Wielandt, Ana María and Zárate, Alejandro J and Kronberg, Udo and Castro, Magdalena and Yamagiwa, Ken and Ito, Takashi and Eishi, Yoshinobu and Contreras, Luis and López-Köstner, Francisco
Revista Medica de Chile, ISSN 0034-9887, 2015, Volume 143, Issue 3, pp. 310 - 319
Human | KRAS protein | PIK3CA protein | BRAF protein | Colonic neoplasms
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52. Full Text Disease: Adenomatous polyposis coli
by Lopez-Kostner, Francisco and Wielandt, Ana Maria and Alvarez, Karin and De La Fuente, Marjorie and Orellana, Paulina and Hurtado, Claudia
Human Genetics, ISSN 0340-6717, 04/2010, Volume 127, Issue 4, p. 481
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53. Full Text Results of a multicentric colorectal cancer screening program in Chile
by Lopez-Kostner, F and Zarate, AJ and Ponce, A and Kronberg, U and Kawachi, H and Okada, T and Tsubaki, M and Ito, T and Nishikage, T and Tanaka, K and Kawano, T and Eishi, Y and Penaloza, P and Estela, R and Karelovic, S and Flores, S
REVISTA MEDICA DE CHILE, ISSN 0034-9887, 06/2018, Volume 146, Issue 6, pp. 685 - 692
Background: Colorectal Cancer Screening Programs (CRCSP) are widely accepted in developed countries. Unfortunately, financial restrictions, low adherence rate... 
MORTALITY | POPULATION | TESTS | RATES | MEDICINE, GENERAL & INTERNAL | OBESITY | Early Detection of Cancer | OCCULT-BLOOD-TEST | ADENOMA DETECTION RATE | Colorectal Neoplasms | BOWEL-CANCER | Endoscopy
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54. Full Text Increased production of soluble TLR2 by lamina propria mononuclear cells from ulcerative colitis patients
by Candia, Enzo and Díaz-Jiménez, David and Langjahr, Patricia and Núñez, Lucía E and de la Fuente, Marjorie and Farfán, Nancy and López-Kostner, Francisco and Abedrapo, Mario and Alvarez-Lobos, Manuel and Pinedo, George and Beltrán, Caroll J and González, Carlos and González, María-Julieta and Quera, Rodrigo and Hermoso, Marcela A
Immunobiology, ISSN 0171-2985, 2011, Volume 217, Issue 6, pp. 634 - 642
Abstract Toll-like receptor 2 (TLR2) is a type I pattern recognition receptor that has been shown to participate in intestinal homeostasis. Its increased... 
Allergy and Immunology | Advanced Basic Science | Inflammatory bowel diseases | Monocytes | Toll-like receptor 2 | Ulcerative colitis | RECRUITMENT | CROHNS-DISEASE | RECOGNITION | POLYMORPHISM | INDUCTION | IMMUNOLOGY | TOLL-LIKE RECEPTOR-2 | INFLAMMATORY-BOWEL-DISEASE | INTESTINAL MACROPHAGES | EXPRESSION | COLONIC-MUCOSA | Leukocytes, Mononuclear - metabolism | Humans | Middle Aged | Sialic Acid Binding Ig-like Lectin 3 - immunology | Crohn Disease - metabolism | Male | Colitis, Ulcerative - immunology | Cell Movement - immunology | Leukocytes, Mononuclear - immunology | Aged, 80 and over | Adult | Female | Receptors, Chemokine - genetics | Sialic Acid Binding Ig-like Lectin 3 - genetics | Gene Expression | Tissue Culture Techniques | Colitis, Ulcerative - metabolism | Solubility | Chemokine CX3CL1 - genetics | Colitis, Ulcerative - pathology | Receptors, Chemokine - immunology | Immunity, Innate | Crohn Disease - immunology | Toll-Like Receptor 2 - biosynthesis | Mucous Membrane - metabolism | Leukocytes, Mononuclear - pathology | Mucous Membrane - pathology | Mucous Membrane - immunology | Biopsy | Crohn Disease - pathology | Chemokine CX3CL1 - immunology | Aged | CX3C Chemokine Receptor 1 | Molecular genetics | Analysis | Gastrointestinal diseases | Crohn's disease | Colitis | Macrophages | Homeostasis | Leukocytes (mononuclear) | Pattern recognition | Immunity | Intestine | TLR2 protein | Organ culture | lamina propria | Toll-like receptors
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55. Full Text Prevalencia y características de mutaciones somáticas del gen KRAS en pacientes chilenos con cáncer colorrectal
by Hurtado, Claudia and Encina, Gonzalo and Wielandt, Ana María and Zárate, Alejandro José and Castro, Magdalena and Carrillo, Katya and Kronberg, Udo and López-Köstner, Francisco
Revista Medica de Chile, ISSN 0034-9887, 2014, Volume 142, Issue 11, pp. 1407 - 1414
Human | KRAS protein | Epidermal growth factor | Receptor | Proto-oncogene proteins | Colorectal neoplasms
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56. Full Text Impacto de las filtraciones anastomóticas en cirugía colorrectal
by López-Köstner, Francisco and Cerda C, Cesar and Wainstein G, Claudio and Kronberg, Udo and Larach K, Andrés and Larach S, Jorge and Zarate, Alejandro J and Castro A, Lorna
Revista Chilena de Cirugia, ISSN 0379-3893, 11/2016, Volume 68, Issue 6, pp. 417 - 421
Introduction Anastomotic leak is the most important complication on colorectal surgery. Objective Analyze the frequency and impact of anastomotic leaks in... 
Anastomosis leak | Morbility | Colorectal surgery
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57. Full Text Análisis molecular del cáncer de colon esporádico
by Hurtado, Claudia and Wielandt, Ana María and Zárate, Alejandro J and Kronberg, Udo and Castro, Magdalena and Yamagiwa, Ken and Ito, Takashi and Eishi, Yoshinobu and Contreras, Luis and López-Köstner, Francisco
Revista médica de Chile, ISSN 0034-9887, 03/2015, Volume 143, Issue 3, pp. 310 - 319
MEDICINE, GENERAL & INTERNAL
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58. Full Text Análisis molecular del cáncer de colon esporádico
by Hurtado, Claudia and Wielandt, Ana María and Zárate, Alejandro J and Kronberg, Udo and Castro, Magdalena and Yamagiwa, Ken and Ito, Takashi and Eishi, Yoshinobu and Contreras, Luis and López-Köstner, Francisco
Revista médica de Chile, ISSN 0034-9887, 03/2015, Volume 143, Issue 3, pp. 310 - 319
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59. Full Text Enfermedad inflamatoria intestinal a partir de una experiencia local
by Simian, Daniela and Estay, Camila and Lubascher, Jaime and Acuña, Raúl and Kronberg, Udo and Figueroa, Carolina and Brahm, Javier and Silva, Guillermo and López-Köstner, Francisco and Wainstein, Claudio and Larach, Andrés and Larach, Jorge and Quera, Rodrigo
Revista Medica de Chile, ISSN 0034-9887, 2014, Volume 142, Issue 8, pp. 1006 - 1013
Inflammatory bowel disease | Crohn disease | Colitis ulcerative | Trends
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60. Full Text EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features
by Alvarez, Karin and Orellana, Paulina and Villarroel, Cynthia and Contreras, Luis and Kawachi, Hiroshi and Kobayashi, Maki and Wielandt, Ana Maria and De la Fuente, Marjorie and Triviño, Juan Carlos and Kronberg, Udo and Carvallo, Pilar and López-Köstner, Francisco
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 09/2017, Volume 39, Issue 9, p. 1010428317724517
Colorectal cancer is a multistep process affecting several signaling pathways including EGFR (epidermal growth factor receptor), a therapeutic target for... 
Immunohistochemistry | Receptor, Epidermal Growth Factor - genetics | Tissue Array Analysis | Colorectal Neoplasms - genetics | Humans | Middle Aged | Transcriptome | Male | Signal Transduction - genetics | Genes, erbB-1 | DNA Mutational Analysis | Polymerase Chain Reaction | Aged, 80 and over | Adult | Female | Aged | High-Throughput Nucleotide Sequencing | Chile | Colorectal Neoplasms - pathology
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