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by Ding, Li and Bailey, Matthew and Bailey, Matthew H and Porta-Pardo, Eduard and Thorsson, Vesteinn and Colaprico, Antonio and Bertrand, Denis and Gibbs, David L and Gibbs, Richard A and Weerasinghe, Amila and Huang, Kuan-lin and Tokheim, Collin and Cortés-Ciriano, Isidro and Jayasinghe, Reyka and Chen, Amy and Chen, Feng and Chen, Chu and Yu, Lihua and Sun, Qiang and Sun, Yichao and Sun, Sam and Olsen, Catharina and Kim, Jaegil and Taylor, Barry S and Taylor, Alison M and Cherniack, Andrew D and Akbani, Rehan and Suphavilai, Chayaporn and Nagarajan, Niranjan and Stuart, Joshua M and Mills, Gordon B and Wyczalkowski, Matthew A and Vincent, Benjamin G and Hutter, Carolyn M and Zenklusen, Jean C and Zenklusen, Jean Claude and Hoadley, Katherine A and Wendl, Michael C and Shmulevich, llya and Shmulevich, Ilya and Lazar, Alexander J and Wheeler, David A and Getz, Gad and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Wang, Min and Wang, Jing and Wang, Jioajiao and Wang, Timothy and Wang, Linghua and Yang, Ju Dong and Yang, Hannah and Yang, Ian and Yang, Liming and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Zhang, Jiexin and Zhang, Jiashan (Julia) and Zhang, Lizhi and Chudamani, Sudha and Liu, Yuexin and Liu, Xiuping and Liu, Wenbin and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Christopher A and Miller, Judy and Reynolds, Sheila and Broom, Bradley M and Hegde, Apurva M and ... and Cancer Genome Atlas Res Network and Cancer Genome Atlas Research Network and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Cell, ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 305 - 320.e10
Journal Article
by Ge, Zhongqi and Leighton, Jake S and Wang, Linghua and Wang, Yumeng and Wang, Min and Wang, Jioajiao and Wang, Jing and Wang, Timothy and Wang, Zhining and Peng, Xinxin and Chen, Chu and Chen, Hu and Chen, Amy and Chen, Zhongyuan and Sun, Yichao and Sun, Yutong and Sun, Qiang and Yao, Fan and Li, Jun and Li, Wei and Zhang, Hailei and Zhang, Jiashan (Julia) and Zhang, Wei and Zhang, Jiexin and Zhang, Hongxin and Zhang, Lizhi and Zhang, Huiwen and Zhang, Hongzheng and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Shriver, Craig D and Hu, Jianhong and Hu, Hai and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Ju Dong and Yang, Hannah and Yang, Ian and Yang, Liming and Zenklusen, Jean C and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Judy and Miller, Michael and Miller, Christopher A and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Liang, Han and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Ryan, Michael and Weinstein, John N and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Gao, Galen F and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 213 - 226.e3
Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using... 
ubiquitin pathway | FBXW7 | therapeutic targets | tumor subtype | biomarker | cancer prognosis | pan-cancer analysis | The Cancer Genome Atlas | CYCLIN-E | RECOGNITION | PHOSPHORYLATION | MDM2 | PTEN | DEGRADATION | ANTAGONISTS | F-BOX PROTEIN | DEUBIQUITINATING ENZYMES | LIGASE | CELL BIOLOGY
Journal Article
by Bailey, Matthew and Bailey, Matthew H and Tokheim, Collin and Porta-Pardo, Eduard and Sengupta, Sohini and Bertrand, Denis and Weerasinghe, Amila and Colaprico, Antonio and Wendl, Michael C and Kim, Jaegil and Reardon, Brendan and Kwok-Shing Ng, Patrick and Jeong, Kang Jin and Cao, Song and Wang, Jioajiao and Wang, Timothy and Wang, Zhining and Wang, Zixing and Wang, Fang and Wang, Linghua and Wang, Jing and Wang, Min and Gao, Qingsong and Gao, Jianjiong and Gao, Galen F and Liu, Xiuping and Liu, Jia and Liu, Wenbin and Liu, Yuexin and Liu, Eric Minwei and Mularoni, Loris and Rubio-Perez, Carlota and Nagarajan, Niranjan and Cortés-Ciriano, Isidro and Zhou, Wanding and Zhou, Daniel Cui and Liang, Wen-Wei and Liang, Han and Hess, Julian M and Hess, Julian and Yellapantula, Venkata D and Tamborero, David and Gonzalez-Perez, Abel and Suphavilai, Chayaporn and Ko, Jia Yu and Khurana, Ekta and Park, Joong-Won and Park, Peter J and Van Allen, Eliezer M and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Ju Dong and Yang, Hannah and Yang, Ian and Yang, Liming and Zenklusen, Jean C and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Zhang, Jiexin and Zhang, Jiashan (Julia) and Zhang, Lizhi and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Christopher A and Miller, Judy and Reynolds, Sheila and Shmulevich, Ilya and ... and Canc Genome Atlas Res Network and MC3 Working Grp and MC3 Working Group and Cancer Genome Atlas Research Network
Cell, ISSN 0092-8674, 08/2018, Volume 174, Issue 4, pp. 1034 - 1035
Journal Article
by Gao, Qingsong and Gao, Galen F and Gao, Jianjiong and Liang, Han and Liang, Wen-Wei and Foltz, Steven M and Mutharasu, Gnanavel and Jayasinghe, Reyka G and Cao, Song and Liao, Wen-Wei and Reynolds, Sheila M and Reynolds, Sheila and Wyczalkowski, Matthew A and Yao, Lijun and Yu, Lihua and Sun, Sam Q and Sun, Yichao and Sun, Qiang and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Min and Wang, Zhining and Wang, Jing and Wang, Timothy and Wang, Linghua and Wang, Jioajiao and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Hongzheng and Zhang, Wei and Zhang, Jiexin and Zhang, Hongxin and Zhang, Hailei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Chudamani, Sudha and Liu, Jia and Liu, Xiuping and Liu, Yuexin and Liu, Wenbin and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Judy and Miller, Christopher A and Miller, Michael and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Li, Wei and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Ryan, Michael and Weinstein, John N and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Gross, Benjamin E and Heins, Zachary J and ... and Canc Genome Atlas Res Network and Fusion Anal Working Grp and Fusion Analysis Working Group and Cancer Genome Atlas Research Network
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 227 - 238.e3
Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using... 
fusion | cancer | translocation | RNA | gene fusions | Biochemistry, Genetics and Molecular Biology(all) | BREAST-CANCER | PATHWAYS | BCR-ABL | GENES | SQUAMOUS-CELL CARCINOMA | MYELOID-LEUKEMIA | LANDSCAPES | MUTATIONS | GENOMIC CHARACTERIZATION | TUMORS | CELL BIOLOGY
Journal Article