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2005, ISBN 0521529565, ix, 249
The process of programmed cell death or apoptosis has, in the decade preceding the publication of this 2005 book, been shown to be centrally involved in the... 
physiology | drug effects | Pathology, Cellular | Apoptosis
Book
Apoptosis, ISSN 1360-8185, 9/2007, Volume 12, Issue 9, pp. 1543 - 1568
Apoptosis has been accepted as a fundamental component in the pathogenesis of cancer, in addition to other human diseases including neurodegeneration, coronary... 
Biochemistry, general | TNFR | TRAF | Oncology | NFkB | Virology | Cell Biology | Biomedicine | Cancer Research | IAPs | Caspases | Smac | Knock out mice | Apoptosis | Cancer | NEURONAL APOPTOSIS | X-LINKED INHIBITOR | SERINE-PROTEASE OMI/HTRA2 | MITOCHONDRIA-DERIVED ACTIVATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | knock out mice | INDUCED PROXIMITY MODEL | apoptosis | CELL BIOLOGY | CELL LUNG-CANCER | SPINAL MUSCULAR-ATROPHY | IN-VIVO | cancer | CYTOCHROME-C RELEASE | caspases | CASPASE ACTIVATION | Caspases - physiology | Proto-Oncogene Proteins c-bcl-2 - physiology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Neoplasm Proteins - physiology | Serine Endopeptidases - physiology | Neoplasm Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - physiology | X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors | Neoplasms - genetics | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Oligonucleotides, Antisense - therapeutic use | Intracellular Signaling Peptides and Proteins - therapeutic use | Mitochondrial Proteins - therapeutic use | Peptide Termination Factors - physiology | Mitochondrial Proteins - physiology | Neoplasm Proteins - therapeutic use | Microtubule-Associated Proteins - antagonists & inhibitors | Caspase Inhibitors | High-Temperature Requirement A Serine Peptidase 2 | Neoplasms - drug therapy | Animals | Protein Kinases - physiology | Checkpoint Kinase 1 | Enzyme Activation | Genetic Vectors | Intracellular Signaling Peptides and Proteins - physiology | Proteins | Cancer therapies
Journal Article
Molecular & Cellular Oncology, ISSN 2372-3556, 07/2019, Volume 6, Issue 4, p. 1607456
A genome-wide small-interfering RNA-based screen identified the transcription factor Specificity Protein 3 (SP3) as a critical factor for Second... 
RNAi | inflammation | IAP antagonist | inhibitor of apoptosis | SP3 | cIAP2 | cIAP1 | Specificity Protein 3 | Smac mimetic | RIPK1 | cancer | MDA-MB-231
Journal Article
Cytokine, ISSN 1043-4666, 09/2013, Volume 63, Issue 3, p. 248
Smac mimetic compounds (SMCs) are a novel class of small molecule antagonists that target the inhibitor of apoptosis (IAP) proteins to induce cancer cell death... 
Journal Article
Cytokine, ISSN 1043-4666, 09/2013, Volume 63, Issue 3, p. 248
Journal Article
Journal Article
Cytokine, ISSN 1043-4666, 09/2013, Volume 63, Issue 3, pp. 248 - 248
Journal Article
Frontiers in Immunology, 02/2014, Volume 5
Mammalian skeletal muscle maintains a robust regenerative capacity throughout life, due largely to the presence of a stem cell population known as satellite... 
muscle regeneration | Myoblasts, Skeletal | skeletal muscle | myogenesis | TNF receptor family | NF-kB
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1
Small-molecule inhibitor of apoptosis (IAP) antagonists, called Smac mimetic compounds (SMCs), sensitize tumours to TNF-alpha-induced killing while... 
ACTIVATION | VIRUS | INDUCED APOPTOSIS | INDUCE | IMMUNOTHERAPY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | NF-KAPPA-B | CANCER | CIAP1 | CELL-DEATH | Interferon-alpha - pharmacology | Interferon-beta - immunology | Inhibitor of Apoptosis Proteins - genetics | Antineoplastic Agents - chemical synthesis | Humans | Tumor Necrosis Factor-alpha - genetics | Vesiculovirus - immunology | T-Lymphocytes, Cytotoxic - drug effects | Brain Neoplasms - immunology | Glioblastoma - genetics | Interferon-alpha - genetics | Tumor Necrosis Factor-alpha - immunology | Interferon-beta - genetics | Vesiculovirus - genetics | Female | Antineoplastic Agents - pharmacology | Brain Neoplasms - mortality | T-Lymphocytes, Cytotoxic - immunology | Poly I-C - pharmacology | Genetic Vectors - chemistry | Genetic Vectors - immunology | Immunity, Innate - drug effects | Signal Transduction | Gene Expression Regulation | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Interferon-alpha - immunology | Xenograft Model Antitumor Assays | Tumor Necrosis Factor-alpha - pharmacology | Adaptive Immunity - drug effects | Animals | Glioblastoma - immunology | Interferon-beta - pharmacology | Thiazoles - chemical synthesis | Survival Analysis | Cell Line, Tumor | Immunologic Memory | Inhibitor of Apoptosis Proteins - immunology | Mice | Thiazoles - pharmacology | Glioblastoma - drug therapy | Glioblastoma - mortality
Journal Article