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PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0135668
6-Formylindolo(3,2-b) carbazole (FICZ) is a photoproduct of tryptophan and an endogenous high affinity ligand for aryl hydrocarbon receptor (AhR). It was... 
ACID-INDUCED DIFFERENTIATION | C-CBL | MULTIDISCIPLINARY SCIENCES | JUVENILE MYELOMONOCYTIC LEUKEMIA | INDUCED BLR1 EXPRESSION | GRANULOCYTIC DIFFERENTIATION | CD38 EXPRESSION | TRANS-RETINOIC ACID | ACUTE MYELOID-LEUKEMIA | SURFACE ANTIGEN | ACUTE PROMYELOCYTIC LEUKEMIA | Biomarkers - metabolism | Proto-Oncogene Proteins c-cbl - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Gene Expression Regulation, Leukemic - drug effects | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Cell Differentiation - drug effects | src-Family Kinases - metabolism | Cell Line, Tumor | HL-60 Cells | Leukemia, Myeloid, Acute - drug therapy | Receptors, Aryl Hydrocarbon - metabolism | ADP-ribosyl Cyclase 1 - metabolism | Antineoplastic Agents - pharmacology | CD11b Antigen - metabolism | Carbazoles - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Tretinoin - pharmacology | Cluster analysis | Flow cytometry | Oxidative metabolism | Leukemia | Lung cancer | Differentiation (biology) | Hydrocarbons | Kinases | Cancer therapies | Metabolites | Aromatic compounds | CD38 antigen | Cell cycle | Cbl-b protein | Physiology | Fluorescence resonance energy transfer | Antigens | CD11b antigen | Phenotypes | Markers | Tryptophan | MAP kinase | Metabolism | Cell differentiation | Clustering | Carbazole | Molecular chains | 1-Phosphatidylinositol 3-kinase | Myeloblastic leukemia | Signaling | Chemotherapy | Acids | Correlation analysis | Stem cells | Mutation | Retinoic acid
Journal Article
Blood, ISSN 0006-4971, 12/2011, Volume 118, Issue 24, pp. 6392 - 6398
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2015, Volume 27, Issue 3, pp. 409 - 425
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Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 3718 - 3718
Abstract Transcription Factor 3 (TCF3) rearrangements are a recurring chromosomal abnormality in B-cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)... 
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Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 4097 - 4097
Abstract Tumor Necrosis Factor-alpha (TNF) is elevated in myeloproliferative neoplasm (MPN) and plays a key role in expansion of the JAK2V617F neoplastic... 
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Journal of Neuroscience Research, ISSN 0360-4012, 10/2003, Volume 74, Issue 2, pp. 296 - 308
Journal Article
Molecular cancer research : MCR, ISSN 1541-7786, 11/2013, Volume 11, Issue 11
Since the advent of tyrosine kinase inhibitors as targeted therapies in cancer, several receptor tyrosine kinases (RTKs) have been identified that are... 
nucleus | receptor tyrosine kinase | Igf1r | rhabdomyosarcoma | Pdgfrα
Journal Article
Cancer research, ISSN 0008-5472, 6/2013, Volume 73, Issue 11, pp. 3356 - 3370
The imatinib paradigm in chronic myeloid leukemia (CML) established continuous BCR-ABL inhibition as a design principle for ABL tyrosine kinase inhibitors... 
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Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 21, pp. 512 - 512
Abstract Abstract 512 Background: BCR-ABL promotes cell cycle progression by interfering with the regulatory functions of p27, a cyclin dependent kinase (Cdk)... 
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 3504 - 3504
Abstract Abstract 3504 The imatinib paradigm established continuous BCR-ABL inhibition as a design principle for ABL tyrosine kinase inhibitors (TKIs).... 
Journal Article
PLoS ONE, 08/2015, Volume 10, Issue 8
6-Formylindolo(3,2-b)carbazole (FICZ) is a photoproduct of tryptophan and an endogenous high affinity ligand for aryl hydrocarbon receptor (AhR). It was... 
Journal Article