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1. Reply to: Long-term tocilizumab efficacy in a patient with psoriatic arthritis and AA amyloidosis
by Lane, Thirusha and Lachmann, H.J
Clinical and Experimental Rheumatology, ISSN 0392-856X, 2017, Volume 35, Issue 1, p. 171
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2. Full Text Consensus guidelines on the testing and clinical management issues associated with HLA and Non-HLA antibodies in transplantation
by Tait, Brian D and Süsal, Caner and Gebel, Howard M and Nickerson, Peter W and Zachary, Andrea A and Claas, Frans H.J and Reed, Elaine F and Bray, Robert A and Campbell, Patricia and Chapman, Jeremy R and Coates, P. Toby and Colvin, Robert B and Cozzi, Emanuele and Doxiadis, Ilias I.N and Fuggle, Susan V and Gill, John and Glotz, Denis and Lachmann, Nils and Mohanakumar, Thalachallour and Suciu-Foca, Nicole and Sumitran-Holgersson, Suchitra and Tanabe, Kazunari and Taylor, Craig J and Tyan, Dolly B and Webster, Angela and Zeevi, Adriana and Opelz, Gerhard and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for Surgery and Gastrosurgical Research and Education, Department of Surgery and Institutionen för kliniska vetenskaper, sektionen för kirurgi och kirurgisk gastroforskning, Avdelningen för kirurgi and Sahlgrenska Academy
Transplantation, ISSN 0041-1337, 01/2013, Volume 95, Issue 1, pp. 19 - 47
Background. The introduction of solid-phase immunoassay (SPI) technology for the detection and characterization of human leukocyte antigen (HLA) antibodies in... 
SURGERY | CLASS-I ANTIBODY | Antibodies | ANTIENDOTHELIAL CELL ANTIBODIES | Transplantation | IMMUNOLOGY | MEDIATED REJECTION | PANEL-REACTIVE ANTIBODIES | HUMAN-LEUKOCYTE ANTIGEN | HIGH-DOSE IVIG | POSITIVE CROSS-MATCH | INCOMPATIBLE KIDNEY-TRANSPLANTATION | HLA | CORONARY-ARTERY-DISEASE | DONOR-SPECIFIC ANTIBODIES | Immunoassay | Flow Cytometry - methods | Humans | Complement System Proteins - immunology | HLA Antigens - immunology | Organ Transplantation | Complement C1q - analysis | Isoantibodies - blood | Complement C4b | Peptide Fragments - blood | Isoantibodies - immunology | Cytotoxicity, Immunologic | Practice Guidelines as Topic | Conferences | Risk groups | Therapeutic applications | Heart transplantation | Lung transplantation | Histocompatibility testing | Risk factors | Graft rejection | Biopsy | Intestine | Islet cells | Pancreas transplantation | Histocompatibility antigen HLA | Immunoassays | Kidney transplantation | Surgery | Kirurgi
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3. Full Text Clinical Immunology Review Series: An approach to the patient with a periodic fever syndrome
by Lachmann, H. J
Clinical & Experimental Immunology, ISSN 0009-9104, 09/2011, Volume 165, Issue 3, pp. 301 - 309
The periodic fever syndromes are disorders of innate immunity. They may be inherited or acquired and present as recurrent attacks of apparently spontaneous... 
inflammation/inflammatory mediators including eicosanoids | tumour antigens | human studies | Human studies | Inflammation/inflammatory mediators including eicosanoids | Tumour antigens | INTERLEUKIN-1-RECEPTOR ANTAGONIST | APHTHOUS STOMATITIS | IMMUNOLOGY | AUTOINFLAMMATORY DISEASE | AA AMYLOIDOSIS | FAMILIAL MEDITERRANEAN FEVER | HYPER-IGD | ISOPRENOID BIOSYNTHESIS | HYPERIMMUNOGLOBULINEMIA-D | SCHNITZLER-SYNDROME | GRANULOMATOUS ARTHRITIS | Immune System Diseases - physiopathology | Humans | Hereditary Autoinflammatory Diseases - immunology | Hereditary Autoinflammatory Diseases - physiopathology | Immune System Diseases - immunology | Immune System Diseases - drug therapy | Hereditary Autoinflammatory Diseases - diagnosis | Hereditary Autoinflammatory Diseases - drug therapy | Syndrome | Immune System Diseases - diagnosis | Autoimmunity | Autoantibodies | Sjogren's syndrome | Recurrent infection | Urticaria | Hypersensitivity | Lung diseases | Inflammation | Immunity | Fever | angioedema | Anaphylaxis | Reviews | Systemic lupus erythematosus | Vasculitis | Children | inflammatory mediators including eicosanoids | Review | inflammation
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4. Full Text The phenotype of TNF receptor-associated autoinflammatory syndrome (TRAPS) at presentation: a series of 158 cases from the Eurofever/EUROTRAPS international registry
by Lachmann, H J and Papa, R and Gerhold, K and Obici, L and Touitou, I and Cantarini, L and Frenkel, J and Anton, J and Kone-Paut, I and Cattalini, M and Bader-Meunier, B and Insalaco, A and Hentgen, V and Merino, R and Modesto, C and Toplak, N and Berendes, R and Ozen, S and Cimaz, R and Jansson, A and Brogan, P A and Hawkins, P N and Ruperto, N and Martini, A and Woo, P and Gattorno, M and Paediat Rheumatology Int Trials and EUROTRAPS and Eurofever Project and Paediatric Rheumatology International Trials Organisation (PRINTO), the EUROTRAPS and the Eurofever Project
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2014, Volume 73, Issue 12, pp. 2160 - 2167
Objective To evaluate the genetic findings, demographic features and clinical presentation of tumour necrosis factor receptor-associated autoinflammatory... 
HETEROGENEITY | DISEASES | GENE | INFLAMMATION | INFEVERS | FEVER-SYNDROME | TNFRSF1A MUTATIONS | RHEUMATOLOGY | PERIODIC SYNDROME TRAPS | FAMILY | Humans | Middle Aged | Child, Preschool | Genotype | Male | Receptors, Tumor Necrosis Factor, Type I - genetics | Disease Progression | Exanthema - etiology | Young Adult | Hereditary Autoinflammatory Diseases - complications | Phenotype | Time Factors | Adolescent | Fever - etiology | Hereditary Autoinflammatory Diseases - physiopathology | Pain - etiology | Adult | Female | Registries | Aged | Retrospective Studies | Child | Cohort Studies | Hereditary Autoinflammatory Diseases - genetics | Tumor necrosis factor | Analysis | Inflammation | Genetic aspects | Research | Risk factors | Genotype & phenotype | Pain | Disease | Bias | Gangrene | Tumor necrosis factor-TNF | Whites | Mutation | Patients | Inflammatory diseases | Fever | Life Sciences | Clinical and Epidemiological Research | Amyloidosis | 1506 | Fever Syndromes
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5. Full Text Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry
by Levy, R and Gérard, L and Kuemmerle-Deschner, J and Lachmann, H J and Koné-Paut, I and Cantarini, L and Woo, P and Naselli, A and Bader-Meunier, B and Insalaco, A and Al-Mayouf, S M and Ozen, S and Hofer, M and Frenkel, J and Modesto, C and Nikishina, I and Schwarz, T and Martino, S and Meini, A and Quartier, P and Martini, A and Ruperto, N and Neven, B and Gattorno, M and Eurofever and PRINTO and for PRINTO and Eurofever
Annals of the Rheumatic Diseases, ISSN 0003-4967, 11/2015, Volume 74, Issue 11, pp. 2043 - 2049
ObjectiveTo evaluate genetic, demographic and clinical features in patients with cryopyrin-associated periodic syndrome (CAPS) from the Eurofever Registry,... 
ARTICULAR SYNDROME | NLRP3 MUTATION | LOW-LEVEL MOSAICISM | SYNDROMES CAPS | GENETIC-HETEROGENEITY | MUCKLE-WELLS-SYNDROME | COLD AUTOINFLAMMATORY SYNDROME | RHEUMATOLOGY | CIAS1 MUTATIONS | AA AMYLOIDOSIS | MULTISYSTEM INFLAMMATORY DISEASE | Arthralgia - etiology | Uveitis - etiology | Conjunctivitis - genetics | Headache - etiology | Exanthema - genetics | Myalgia - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Child, Preschool | Infant | Male | Papilledema - genetics | Arthritis - genetics | Meningitis - etiology | Exanthema - etiology | Young Adult | Arthritis - etiology | Germ-Line Mutation | Adult | Female | Registries | Retrospective Studies | Arthralgia - genetics | Child | Cryopyrin-Associated Periodic Syndromes - complications | Meningitis - genetics | Severity of Illness Index | Cryopyrin-Associated Periodic Syndromes - genetics | Europe | Genotype | Myalgia - etiology | Hearing Loss, Sensorineural - genetics | Headache - genetics | Cryopyrin-Associated Periodic Syndromes - physiopathology | Carrier Proteins - genetics | Phenotype | Hearing Loss, Sensorineural - etiology | Adolescent | Alleles | Heterozygote | Mutation | Uveitis - genetics | Conjunctivitis - etiology | Cohort Studies | Papilledema - etiology | Complications and side effects | Nervous system diseases | Care and treatment | Research | Cryopyrin-associated periodic syndromes | Studies | Genotype & phenotype | Statistical analysis | Disease | Cold | Meningitis | Family medical history | Hearing impairment | Fever | Chronic illnesses
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6. Full Text Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrin-associated periodic syndrome across different severity phenotypes
by Kuemmerle-Deschner, Jasmin B and Hachulla, E and Cartwright, R and Hawkins, P N and Tran, T A and Bader-Meunier, B and Hoyer, J and Gattorno, M and Gul, A and Smith, J and Leslie, K S and Jiménez, S and Morell-Dubois, S and Davis, N and Patel, N and Widmer, A and Preiss, R and Lachmann, H J
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2011, Volume 70, Issue 12, pp. 2095 - 2102
Objective Longer-term effects of prolonged selective interleukin-1β blockade with canakinumab were evaluated in the largest cohort of cryopyrin-associated... 
ARTICULAR SYNDROME | ANTAGONIST | FOLLOW-UP | ANTIBODY | MUCKLE-WELLS-SYNDROME | COLD AUTOINFLAMMATORY SYNDROME | ANAKINRA | MUTATIONS | RHEUMATOLOGY | RILONACEPT INTERLEUKIN-1 TRAP | MULTISYSTEM INFLAMMATORY DISEASE | Cryopyrin-Associated Periodic Syndromes - immunology | Severity of Illness Index | Body Weight | Drug Administration Schedule | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Child, Preschool | Antibodies, Monoclonal - therapeutic use | Treatment Outcome | Cryopyrin-Associated Periodic Syndromes - drug therapy | Dose-Response Relationship, Drug | Young Adult | Phenotype | C-Reactive Protein - metabolism | Antibodies, Monoclonal - administration & dosage | Injections, Subcutaneous | Adolescent | Adult | Aged | Child | Interleukin-1beta - antagonists & inhibitors | Skin diseases | Cohort analysis | Care and treatment | Research | Proteins | Studies | Hospitals | Disease | Nervous system | Adults | Inflammation | Mutation | Inflammatory diseases
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7. Full Text The Phenotype and Genotype of Mevalonate Kinase Deficiency: A Series of 114 Cases From the Eurofever Registry
by Haar, N. Ter and Jeyaratnam, J and Lachmann, H.J and Simon, A and Brogan, P.A and Doglio, M and Cattalini, M and Anton, J and Modesto, C and Quartier, P and Hoppenreijs, E.P and Martino, S and Insalaco, A and Cantarini, L and Lepore, L and Alessio, M and Calvo Penades, I and Boros, C and Consolini, R and Rigante, D and Russo, R and Pachlopnik Schmid, J and Lane, T and Martini, A and Ruperto, N and Frenkel, J and Gattorno, M and Paediat Rheumatology Int Trials and Paediatric Rheumatology International Trials Organisation and Eurofever Project
Arthritis & Rheumatology, ISSN 2326-5191, 2016, Volume 68, Issue 11, pp. 2795 - 2805
ObjectiveMevalonate kinase deficiency (MKD) is a rare metabolic disease characterized by recurrent inflammatory episodes. This study was undertaken to describe... 
MVK | HYPER-IGD | PERIODIC FEVER SYNDROME | ACIDURIA | HYPERIMMUNOGLOBULINEMIA-D | AUTOINFLAMMATORY DISEASES | MUTATIONS | SPECTRUM | RHEUMATOLOGY | Arthralgia - etiology | Uveitis - etiology | Humans | Child, Preschool | Lymphadenopathy - etiology | Male | Arthralgia - physiopathology | Arthritis - genetics | Stomatitis, Aphthous - genetics | Cerebellar Diseases - physiopathology | Amyloidosis - genetics | Skin Diseases - physiopathology | Amyloidosis - etiology | Child | Stomatitis, Aphthous - etiology | Infant, Newborn | Myalgia - physiopathology | Amyloidosis - physiopathology | Genotype | Headache - physiopathology | Vomiting - genetics | Phenotype | Diarrhea - genetics | Abdominal Pain - genetics | Adolescent | Age of Onset | Intellectual Disability - etiology | Uveitis - genetics | Vomiting - physiopathology | Conjunctivitis - etiology | Conjunctivitis - genetics | Arthritis - physiopathology | Headache - etiology | Skin Diseases - genetics | Mevalonate Kinase Deficiency - physiopathology | Myalgia - genetics | Cerebellar Diseases - etiology | Diarrhea - physiopathology | Infant | Mevalonate Kinase Deficiency - genetics | Intellectual Disability - genetics | Pharyngitis - genetics | Arthritis - etiology | Female | Registries | Retrospective Studies | Arthralgia - genetics | Pharyngitis - physiopathology | Abdominal Pain - etiology | Pharyngitis - etiology | Lymphadenopathy - genetics | Abdominal Pain - physiopathology | Myalgia - etiology | Phosphotransferases (Alcohol Group Acceptor) - genetics | Headache - genetics | Intellectual Disability - physiopathology | Skin Diseases - etiology | Cerebellar Diseases - genetics | Conjunctivitis - physiopathology | Mevalonate Kinase Deficiency - complications | Stomatitis, Aphthous - physiopathology | Vomiting - etiology | Diarrhea - etiology | Lymphadenopathy - physiopathology | Uveitis - physiopathology | Kinases | Genotype & phenotype | Index Medicus | Abridged Index Medicus
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8. Full Text Validation of the Auto-Inflammatory Diseases Activity Index (AIDAI) for hereditary recurrent fever syndromes
by Piram, Maryam and Koné-Paut, Isabelle and Lachmann, Helen J and Frenkel, Joost and Ozen, Seza and Kuemmerle-Deschner, Jasmin and Stojanov, Silvia and Simon, Anna and Finetti, Martina and Sormani, Maria Pia and Martini, Alberto and Gattorno, Marco and Ruperto, Nicolino and EUROTRAPS Network and Paediat Rheumatology Int Trials and EUROFEVER Network and EUROFEVER, EUROTRAPS and the Paediatric Rheumatology International Trials Organisation (PRINTO) networks
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2014, Volume 73, Issue 12, pp. 2168 - 2173
Objectives To validate the Auto-Inflammatory Diseases Activity Index (AIDAI) in the four major hereditary recurrent fever syndromes (HRFs): familial... 
Disease Activity | Fever Syndromes | Familial Mediterranean Fever | HORIZONTAL LINE | CRITERIA | SYSTEMIC-LUPUS-ERYTHEMATOSUS | VISUAL ANALOG SCALES | IMPROVEMENT | CONSENSUS | PRELIMINARY DEFINITION | AUTOINFLAMMATORY DISEASES | RHEUMATOLOGY | ARTHRITIS | RILONACEPT | Severity of Illness Index | Reproducibility of Results | Prospective Studies | Area Under Curve | Mevalonate Kinase Deficiency - physiopathology | Humans | Male | Hereditary Autoinflammatory Diseases - diagnosis | Fever | Mevalonate Kinase Deficiency - diagnosis | Cryopyrin-Associated Periodic Syndromes - physiopathology | Young Adult | Familial Mediterranean Fever - physiopathology | Cryopyrin-Associated Periodic Syndromes - diagnosis | Adolescent | Hereditary Autoinflammatory Diseases - physiopathology | Adult | Female | ROC Curve | Familial Mediterranean Fever - diagnosis | Child | Cohort Studies | Usage | Relapse | Hereditary autoinflammatory diseases | Clinical trials | Research | Risk factors | Diseases | Diaries | Parents & parenting | Pain | Orphans | Physicians | Pathogenesis | Adults | Clinical medicine | Patients | Clinical and Epidemiological Research | 1506
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9. Full Text A matched comparison of cyclophosphamide, bortezomib and dexamethasone (CVD) versus risk-adapted cyclophosphamide, thalidomide and dexamethasone (CTD) in AL amyloidosis
by Venner, S D J and Venner, C.P and Gillmore, J.D and Sachchithanantham, S and Mahmood, S and Lane, T and Foard, D and Rannigan, L and Gibbs, S.D.J and Pinney, J.H and Whelan, C.J and Lachmann, H.J and Hawkins, P.N and Wechalekar, A.D
Leukemia, ISSN 0887-6924, 12/2014, Volume 28, Issue 12, pp. 2304 - 2310
Despite improvements in therapy amyloid light-chain (AL) amyloidosis, there are few studies comparing different regimens. Here we present a matched comparison... 
SURVIVAL | BRAIN NATRIURETIC PEPTIDE | LIGHT-CHAIN AMYLOIDOSIS | PLUS DEXAMETHASONE | EFFICACY | ONCOLOGY | LENALIDOMIDE | HIGH-DOSE MELPHALAN | SYSTEMIC AMYLOIDOSIS | STEM-CELL TRANSPLANTATION | HEMATOLOGY | CARDIAC BIOMARKERS | Cyclophosphamide - administration & dosage | Bortezomib | Dexamethasone - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Pyrazines - administration & dosage | Amyloidosis - mortality | Amyloidosis - diagnosis | Male | Treatment Outcome | Amyloidosis - drug therapy | Thalidomide - administration & dosage | Immunoglobulin Light Chains - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Adult | Female | Aged | Boronic Acids - administration & dosage | Cohort Studies | Chemotherapy | Amyloidosis | Drug therapy | Patient outcomes | Methods | Cancer
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10. Full Text An International registry on Autoinflammatory diseases: the Eurofever experience
by Toplak, Natasa and Frenkel, Joost and Ozen, Seza and Lachmann, Helen J and Woo, Patricia and Koné-Paut, Isabelle and De Benedetti, Fabrizio and Neven, Benedicte and Hofer, Michael and Dolezalova, Pavla and Kümmerle-Deschner, Jasmin and Touitou, Isabelle and Hentgen, Veronique and Simon, Anna and Girschick, Herman and Rose, Carlos and Wouters, Carine and Vesely, Richard and Arostegui, Juan and Stojanov, Silvia and Ozgodan, Huri and Martini, Alberto and Ruperto, Nicolino and Gattorno, Marco and Eurotraps Project and Paediat Rheumatology Int Trials and Eurofever Project and Paediatric Rheumatology International Trials Organisation (PRINTO), Eurotraps and Eurofever Projects and for the Paediatric Rheumatology International Trials Organisation (PRINTO), Eurotraps and Eurofever Projects
Annals of the Rheumatic Diseases, ISSN 0003-4967, 07/2012, Volume 71, Issue 7, pp. 1177 - 1182
Objective To report on the demographic data from the first 18 months of enrollment to an international registry on autoinflammatory diseases in the context of... 
ENCODING MEVALONATE KINASE | DIAGNOSIS | ANTAGONIST | FAMILIAL MEDITERRANEAN FEVER | GENE | AUTO-INFLAMMATORY DISEASES | MUTATIONS | RHEUMATOLOGY | HEREDITARY PERIODIC FEVER | DEFICIENCY | PATIENT REGISTRY | Demography | Humans | Middle Aged | Behcet Syndrome - epidemiology | Child, Preschool | Infant | Male | Young Adult | Aged, 80 and over | Adult | Female | Registries | Cryopyrin-Associated Periodic Syndromes - epidemiology | Familial Mediterranean Fever - epidemiology | Child | Genetic Predisposition to Disease | Cryopyrin-Associated Periodic Syndromes - genetics | Global Health | Familial Mediterranean Fever - genetics | International Cooperation | Hereditary Autoinflammatory Diseases - diagnosis | Genes, Recessive | Cryopyrin-Associated Periodic Syndromes - diagnosis | Adolescent | Heterozygote | Aged | Behcet Syndrome - diagnosis | Familial Mediterranean Fever - diagnosis | Behcet Syndrome - genetics | Internet | Hereditary Autoinflammatory Diseases - epidemiology | Hereditary Autoinflammatory Diseases - genetics | Physician and patient | Medical care | Care and treatment | Management | Patients | Methods
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11. Full Text How not to miss autoinflammatory diseases masquerading as urticaria
by Krause, K and Grattan, C.E and Bindslev-Jensen, C and Gattorno, M and Kallinich, T and Koning, H.D. de and Lachmann, H.J and Lipsker, D and Navarini, A.A and Simon, A and Traidl-Hoffmann, C and Maurer, M
Allergy, ISSN 0105-4538, 2012, Volume 67, Issue 12, pp. 1465 - 1474
Urticarial skin reactions are one of the most frequent problems seen by allergists and clinical immunologists in daily practice. The most common reason for... 
autoinflammation | interleukin‐1 | chnitzler's syndrome | cryopyrin‐associated periodic syndrome | urticaria | Schnitzler's syndrome | cryopyrin-associated periodic syndrome | interleukin-1 | JUVENILE IDIOPATHIC ARTHRITIS | PHASE-III | OPEN-LABEL | IMMUNOLOGY | RILONACEPT INTERLEUKIN-1 TRAP | CIAS1 MUTATIONS | HEREDITARY PERIODIC FEVER | ALLERGY | DOUBLE-BLIND | QUALITY-OF-LIFE | SCHNITZLER-SYNDROME | ONSET STILLS-DISEASE | Exanthema - diagnosis | Exanthema - etiology | Inflammation - complications | Diagnosis, Differential | Urticaria - etiology | Urticaria - diagnosis | Humans | Autoimmune Diseases - complications | Autoimmune Diseases - diagnosis | Inflammation - diagnosis | Urticaria | Skin diseases | Autoimmune diseases | Medical diagnosis | Inflammatory diseases | Allergies | Antihistamines | Vasculitis | Arthralgia | Exanthema | Interleukin 1 | Fatigue | Amyloidosis | Arthritis | Inflammation | Skin | Fever
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