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by Tomlinson, Ian P.M and Webb, Emily and Carvajal-Carmona, Luis and Broderick, Peter and Howarth, Kimberley and Pittman, Alan M and Spain, Sarah and Lubbe, Steven and Walther, Axel and Sullivan, Kate and Jaeger, Emma and Fielding, Sarah and Rowan, Andrew and Vijayakrishnan, Jayaram and Domingo, Enric and Chandler, Ian and Kemp, Zoe and Qureshi, Mobshra and Farrington, Susan M and Tenesa, Albert and Prendergast, James G.D and Barnetson, Rebecca A and Penegar, Steven and Barclay, Ella and Wood, Wendy and Martin, Lynn and Gorman, Maggie and Thomas, Huw and Peto, Julian and Bishop, D. Timothy and Gray, Richard and Maher, Eamonn R and Lucassen, Anneke and Kerr, David and Evans, D. Gareth R and Schafmayer, Clemens and Buch, Stephan and Völzke, Henry and Hampe, Jochen and Schreiber, Stefan and John, Ulrich and Koessler, Thibaud and Pharoah, Paul and Van Wezel, Tom and Morreau, Hans and Wijnen, Juul T and Hopper, John L and Southey, Melissa C and Giles, Graham G and Severi, Gianluca and Castellví-Bel, Sergi and Ruiz-Ponte, Clara and Carracedo, Angel and Castells, Antoni and Försti, Asta and Hemminki, Kari and Vodicka, Pavel and Naccarati, Alessio and Lipton, Lara and Ho, Judy W.C and Cheng, K.K and Sham, Pak C and Luk, J and Agúndez, Jose A.G and Ladero, Jose M and De La Hoya, Miguel and Caldés, Trinidad and Niittymäki, Iina and Tuupanen, Sari and Karhu, Auli and Aaltonen, Lauri and Cazier, Jean-Baptiste and Campbell, Harry and Dunlop, Malcolm G and Houlston, Richard S and EPICOLON Consortium and CORGI Consortium and The EPICOLON Consortium and The CORGI Consortium
Nature Genetics, ISSN 1061-4036, 05/2008, Volume 40, Issue 5, pp. 623 - 630
Journal Article
Hepatitis monthly, ISSN 1735-143X, 09/2011, Volume 11, Issue 9, p. 698
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 12/2008, Volume 17, Issue 23, pp. 3720 - 3727
Journal Article
Journal Article
Liver International, ISSN 1478-3223, 01/2015, Volume 35, Issue 1, pp. 90 - 100
Journal Article
Hepatitis Monthly, ISSN 1735-143X, 09/2011, Volume 11, Issue 9, pp. 698 - 700
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 01/2005, Volume 59, Issue 1, pp. 62 - 68
Aims To study the effect of CYP2C8*3, the most common CYP2C8 variant allele on the dis-position of (R)-ibuprofen and the association of CYP2C8*3 with variant... 
phenotype | CYP2C9 | CYP2C8 | genotype | Genotype | Phenotype | Cytochrome P-450 CYP2C9 | Cytochrome P-450 CYP2C8 | Stereoisomerism | Gene Frequency | Humans | Ibuprofen - pharmacokinetics | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Male | Chromatography, High Pressure Liquid | Mutation - genetics | Homozygote | Female | Heterozygote | Polymorphism, Genetic - genetics | Drug Metabolism
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 02/2012, Volume 27, Issue 2, pp. 279 - 285
Background and Aim:  Polymorphisms at the interleukin‐28B ( IL28B ) gene predict therapeutic response in chronic hepatitis C virus genotype 1 (CHC‐1)... 
interferon‐λ3 | pegylated interferon | ribavirin | interleukin‐28B gene | hepatitis C | Hepatitis C | Interferon-λ3 | Pegylated interferon | Ribavirin | Interleukin-28B gene | interferon-?3 | SUSTAINED VIROLOGICAL RESPONSE | IL28B | GENOTYPE | interleukin-28B gene | 28B | GASTROENTEROLOGY & HEPATOLOGY | PEGINTERFERON | FAILURE | Haplotypes | Recombinant Proteins - therapeutic use | Multivariate Analysis | Recurrence | Humans | Middle Aged | Hepacivirus - genetics | Male | RNA, Viral - blood | Polyethylene Glycols - therapeutic use | Viral Load | Patient Selection | Young Adult | Interleukins - genetics | Time Factors | Adult | Female | Drug Therapy, Combination | Odds Ratio | Hepacivirus - drug effects | Antiviral Agents - therapeutic use | Gene Frequency | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Logistic Models | Treatment Outcome | Biomarkers - blood | Chi-Square Distribution | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Spain | Phenotype | Hepatitis C, Chronic - immunology | Interferon alpha-2 | Aged | Polymorphism, Single Nucleotide | Hepatitis C, Chronic - genetics | Medical colleges | Antiviral agents | Phosphatases | Molecular genetics | Genes | Aspartate | Biological response modifiers | Interleukins | Genetic research | Genetic aspects | Hepatitis C virus | Health aspects | Alkaline phosphatase | Chronic infection | Data processing | Single-nucleotide polymorphism | Multivariate analysis | Gene polymorphism | Cholesterol | Alanine transaminase | Aspartate aminotransferase | Interferon | Models | gamma -Glutamylcyclotransferase | Age
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37998
Background/Aims: Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B... 
SUSTAINED VIROLOGICAL RESPONSE | FIBROSIS | CLEARANCE | HEPATOCELLULAR-CARCINOMA | THERAPY | GENOTYPE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | GENOME-WIDE-ASSOCIATION | NATURAL-HISTORY | PROGRESSION | Liver Neoplasms - virology | Liver Diseases - virology | Hepatitis C, Chronic - pathology | Liver Diseases - genetics | Liver Neoplasms - genetics | Humans | Middle Aged | Liver Diseases - pathology | Hepatitis C, Chronic - virology | Hepacivirus - pathogenicity | Male | Carcinoma, Hepatocellular - virology | Interleukins - genetics | Phenotype | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Female | Liver Neoplasms - pathology | Polymorphism, Single Nucleotide | Hepatitis C, Chronic - genetics | Infection | Medical research | Analysis | Genes | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Hepatitis C virus | Health aspects | Liver | Genomics | Chronic infection | Viruses | Amino acids | Hepatocellular carcinoma | Infections | Biochemistry | Single-nucleotide polymorphism | Multivariate analysis | Gene polymorphism | Hepatitis | Liver cancer | Fatty liver | Gastroenterology | Liver diseases | Gene expression | Patients | Steatosis | Carriers | Homozygotes | Studies | Hospitals | Biopsy | Alleles | Fibrosis | Interferon | Hepatitis C | Polymorphism
Journal Article