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by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Index Medicus | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
by Dastani, Zari and Hivert, Marie-France and Timpson, Nicholas and Perry, John R. B and Yuan, Xin and Scott, Robert A and Henneman, Peter and Heid, Iris M and Kizer, Jorge R and Lyytikäinen, Leo-Pekka and Fuchsberger, Christian and Tanaka, Toshiko and Morris, Anew P and Small, Kerrin and Isaacs, Aaron and Beekman, Marian and Coassin, Stefan and Lohman, Kurt and Qi, Lu and Kanoni, Stavroula and Pankow, James S and Uh, Hae-Won and Wu, Ying and Bidulescu, Aurelian and Rasmussen-Torvik, Laura J and Greenwood, Celia M. T and Ladouceur, Martin and Grimsby, Jonna and Manning, Alisa K and Liu, Ching-Ti and Kooner, Jaspal and Mooser, Vincent E and Vollenweider, Peter and Kapur, Karen A and Chambers, John and Wareham, Nicholas J and Langenberg, Claudia and Frants, Rune and Willems-Vandijk, Ko and Oostra, Ben A and Willems, Sara M and Lamina, Claudia and Winkler, Thomas W and Psaty, Bruce M and Tracy, Russell P and Brody, Jennifer and Chen, Ida and Viikari, Jorma and Kähönen, Mika and Pramstaller, Peter P and Evans, David M and St Pourcain, Beate and Sattar, Naveed and Wood, Anew R and Bandinelli, Stefania and Carlson, Olga D and Egan, Josephine M and Böhringer, Stefan and van Heemst, Diana and Kedenko, Lyudmyla and Kristiansson, Kati and Nuotio, Marja-Liisa and Loo, Britt-Marie and Harris, Tamara and Garcia, Melissa and Kanaya, Alka and Haun, Margot and Klopp, Norman and Wichmann, H.-Erich and Deloukas, Panos and Katsareli, Efi and Couper, David J and Duncan, Bruce B and Kloppenburg, Margreet and Adair, Linda S and Borja, Judith B and Wilson, James G and Musani, Solomon and Guo, Xiuqing and Johnson, Toby and Semple, Robert and Teslovich, Tanya M and Allison, Matthew A and Redline, Susan and Buxbaum, Sarah G and Mohlke, Karen L and Meulenbelt, Ingrid and Ballantyne, Christie M and Dedoussis, George V and Hu, Frank B and Liu, Yongmei and Paulweber, Bernhard and Spector, Timothy D and Slagboom, P. Eline and Ferrucci, Luigi and Jula, Antti and Perola, Markus and Raitakari, Olli and Florez, Jose C and Salomaa, Veikko and ... and GLGC Investigators and DIAGRAM Consortium and MAGIC Consortium and MuTHER Consortium and Global B Pgen Consortium and MAGIC investigators and Procardis Consortium and DIAGRAM+ Consortium and GLGC Consortium and GIANT Consortium
PLoS genetics, ISSN 1553-7390, 2012, Volume 8, Issue 3, pp. e1002607 - e1002607
Journal Article
by Wang, Thomas J, MD and Zhang, Feng, PhD and Richards, J Brent, MD and Kestenbaum, Bryan, MD and van Meurs, Joyce B, PhD and Berry, Diane, MSc and Kiel, Douglas P, MD and Streeten, Elizabeth A, MD and Ohlsson, Claes, Prof and Koller, Daniel L, PhD and Peltonen, Leena, Prof and Cooper, Jason D, PhD and O'Reilly, Paul F, PhD and Houston, Denise K, PhD and Glazer, Nicole L, PhD and Vandenput, Liesbeth, PhD and Peacock, Munro, Prof and Shi, Julia, MSc and Rivadeneira, Fernando, PhD and McCarthy, Mark I, Prof and Anneli, Pouta, PhD and de Boer, Ian H, MD and Mangino, Massimo, PhD and Kato, Bernet, PhD and Smyth, Deborah J, BSc and Booth, Sarah L, Prof and Jacques, Paul F, ScD and Burke, Greg L, Prof and Goodarzi, Mark, Prof and Cheung, Ching-Lung, PhD and Wolf, Myles, MD and Rice, Kenneth, PhD and Goltzman, David, Prof and Hidiroglou, Nick, PhD and Ladouceur, Martin, PhD and Wareham, Nicholas J, Prof and Hocking, Lynne J, PhD and Hart, Deborah, PhD and Arden, Nigel K, Prof and Cooper, Cyrus, Prof and Malik, Suneil, PhD and Fraser, William D, Prof and Hartikainen, Anna-Liisa, Prof and Zhai, Guangju, PhD and Macdonald, Helen M, PhD and Forouhi, Nita G, FFPH and Loos, Ruth JF, PhD and Reid, David M, Prof and Hakim, Alan, MA and Dennison, Elaine, PhD and Liu, Yongmei, PhD and Power, Chris, Prof and Stevens, Helen E, HNC and Jaana, Laitinen, PhD and Vasan, Ramachandran S, Prof and Soranzo, Nicole, PhD and Bojunga, Jörg, MD and Psaty, Bruce M, Prof and Lorentzon, Mattias, PhD and Foroud, Tatiana, Prof and Harris, Tamara B, MD and Hofman, Albert, Prof and Jansson, John-Olov, Prof and Cauley, Jane A, PhD and Uitterlinden, Andre G, Prof and Gibson, Quince, MBA and Järvelin, Marjo-Riitta, Prof and Karasik, David, PhD and Siscovick, David S, Prof and Econs, Michael J, Prof and Kritchevsky, Stephen B, Prof and Florez, Jose C, PhD and Todd, John A, Prof and Dupuis, Josee, Prof and Hyppönen, Elina, PhD and Spector, Timothy D, Prof and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin and Institute of Neuroscience and Physiology, Department of Physiology and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi and Institute of Medicine, Department of Internal Medicine
The Lancet, ISSN 0140-6736, 2010, Volume 376, Issue 9736, pp. 180 - 188
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 05/2017, Volume 19, Issue 5, pp. 713 - 720
Aims: To assess whether the dual-hormone (insulin and glucagon) artificial pancreas reduces hypoglycaemia compared to the single-hormone (insulin alone)... 
randomised trial | type 1 diabetes | insulin therapy | hypoglycaemia | artificial pancreas, closed‐loop insulin delivery, glucagon | artificial pancreas, closed-loop insulin delivery, glucagon | SYSTEM | FREE-LIVING CONDITIONS | GLYCEMIC CONTROL | SAFETY | closed-loop insulin delivery | CHILDREN | HOME-USE | ENDOCRINOLOGY & METABOLISM | HYPOGLYCEMIA | glucagon | artificial pancreas | LOOP INSULIN DELIVERY | Glycated Hemoglobin A - analysis | Hypoglycemia - epidemiology | Pancreas, Artificial - adverse effects | Humans | Middle Aged | Glucagon - administration & dosage | Hormone Replacement Therapy - instrumentation | Risk | Hormone Replacement Therapy - adverse effects | Diabetes Mellitus, Type 1 - therapy | Activities of Daily Living | Hypoglycemia - prevention & control | Infusion Pumps - adverse effects | Adult | Hypoglycemia - chemically induced | Patient Education as Topic | Hyperglycemia - prevention & control | Monitoring, Ambulatory - instrumentation | Quebec - epidemiology | Blood Glucose - analysis | Insulin Infusion Systems - adverse effects | Insulin - administration & dosage | Combined Modality Therapy - adverse effects | Diabetes Mellitus, Type 1 - drug therapy | Cross-Over Studies | Diabetes Mellitus, Type 1 - blood | Glucagon - therapeutic use | Glucagon - adverse effects | Insulin - adverse effects | Insulin - therapeutic use | Spinal cord | Retina | Sensors | Diabetes | Hypoglycemia | Pancreas | Man machine interaction | Index Medicus
Journal Article