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Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0170684 - e0170684
Abdominal obesity is a key contributor of metabolic disease. Recent trials suggest that dietary fat quality affects abdominal fat content, where palmitic acid... 
PLASMA | WAIST CIRCUMFERENCE | MULTIDISCIPLINARY SCIENCES | HUMANS | RISK | ANTHROPOMETRIC MEASURES | SEX-DIFFERENCES | SATURATED FAT | INSULIN SENSITIVITY | ADIPOSE-TISSUE | LIVER FAT | Linoleic Acid - blood | Gene Expression | Cross-Sectional Studies | Humans | Middle Aged | Obesity, Abdominal - diagnosis | Obesity, Abdominal - physiopathology | Linear Models | Male | Stearoyl-CoA Desaturase - genetics | Linoleoyl-CoA Desaturase - genetics | Eicosapentaenoic Acid - blood | Linoleoyl-CoA Desaturase - blood | Obesity, Abdominal - blood | Docosahexaenoic Acids - blood | Palmitic Acid - blood | Stearoyl-CoA Desaturase - blood | Dietary Fats - administration & dosage | Female | Cohort Studies | alpha-Linolenic Acid - blood | Prevention | Obesity | Fatty acid desaturases | Aged | Research | Health aspects | Saturated fatty acids | Neurosciences | Body fat | Polyunsaturated fatty acids | Anthropometry | Population studies | Family medical history | Palmitic acid | Desaturase | Epidemiology | Confidence intervals | Regression models | Consent | Population | Quartiles | Cardiology | Cross sections | Public health | Desaturation | Vegetable oils | Enzymes | Statistical analysis | Oils | Gender differences | Regression analysis | Fatty acids | Cholesterol | Linoleic acid | Abdomen | Medicine | Studies | Gas chromatography | Nutrition research | Hospitals | Linolenic acid | Diet | Womens health | Biomarkers | Oils & fats | Insulin resistance | Models | Lifestyles | Eicosapentaenoic acid | Metabolic disorders | Index Medicus | Hälsovetenskaper | Näringslära | Medical and Health Sciences | Medicin och hälsovetenskap | Nutrition and Dietetics | Health Sciences
Journal Article
by Kilpeläinen, Tuomas O and Bentley, Amy R and Noordam, Raymond and Sung, Yun Ju and Schwander, Karen and Winkler, Thomas W and Jakupović, Hermina and Chasman, Daniel I and Manning, Alisa and Ntalla, Ioanna and Aschard, Hugues and Brown, Michael R and de las Fuentes, Lisa and Franceschini, Nora and Guo, Xiuqing and Vojinovic, Dina and Aslibekyan, Stella and Feitosa, Mary F and Kho, Minjung and Musani, Solomon K and Richard, Melissa and Wang, Heming and Wang, Zhe and Bartz, Traci M and Bielak, Lawrence F and Campbell, Archie and Dorajoo, Rajkumar and Fisher, Virginia and Hartwig, Fernando P and Horimoto, Andrea R. V. R and Li, Changwei and Lohman, Kurt K and Marten, Jonathan and Sim, Xueling and Smith, Albert V and Tajuddin, Salman M and Alver, Maris and Amini, Marzyeh and Boissel, Mathilde and Chai, Jin Fang and Chen, Xu and Divers, Jasmin and Evangelou, Evangelos and Gao, Chuan and Graff, Mariaelisa and Harris, Sarah E and He, Meian and Hsu, Fang-Chi and Jackson, Anne U and Zhao, Jing Hua and Kraja, Aldi T and Kühnel, Brigitte and Laguzzi, Federica and Lyytikäinen, Leo-Pekka and Nolte, Ilja M and Rauramaa, Rainer and Riaz, Muhammad and Robino, Antonietta and Rueedi, Rico and Stringham, Heather M and Takeuchi, Fumihiko and van der Most, Peter J and Varga, Tibor V and Verweij, Niek and Ware, Erin B and Wen, Wanqing and Li, Xiaoyin and Yanek, Lisa R and Amin, Najaf and Arnett, Donna K and Boerwinkle, Eric and Brumat, Marco and Cade, Brian and Canouil, Mickaël and Chen, Yii-Der Ida and Concas, Maria Pina and Connell, John and de Mutsert, Renée and de Silva, H. Janaka and de Vries, Paul S and Demirkan, Ayşe and Ding, Jingzhong and Eaton, Charles B and Faul, Jessica D and Friedlander, Yechiel and Gabriel, Kelley P and Ghanbari, Mohsen and Giulianini, Franco and Gu, Chi Charles and Gu, Dongfeng and Harris, Tamara B and He, Jiang and Heikkinen, Sami and Heng, Chew-Kiat and Hunt, Steven C and Ikram, M. Arfan and Jonas, Jost B and Koh, Woon-Puay and Komulainen, Pirjo and Krieger, Jose E and ... and Lifelines Cohort Study
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 376 - 11
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects.... 
INDIVIDUALS | METAANALYSIS | CARBOXYLASE | SNP | MULTIDISCIPLINARY SCIENCES | WIDE ASSOCIATION | REVEAL | EXERCISE | Lipoproteins (low density) | Physical activity | Muscles | Lipids | Genomes | Metabolism | Loci | Low density lipoprotein | Blood | Cholesterol | Genetic effects | Gene loci | Lipid metabolism | Lipoproteins (high density) | Index Medicus
Journal Article
Conference Proceeding
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A10756 - A10756
Introduction and AimsThe relationship between intake of saturated fats and subclinical atherosclerosis is unclear and poorly investigated. We aimed to... 
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A14950 - A14950
AimSmoking is associated with carotid intima-media thickness (C-IMT). However, knowledge about how genetics may influence this association is limited. We... 
Journal Article
by Feitosa, Mary F and Kraja, Aldi T and Chasman, Daniel I and Sung, Yun J and Winkler, Thomas W and Ntalla, Ioanna and Guo, Xiuqing and Franceschini, Nora and Cheng, Ching-Yu and Sim, Xueling and Vojinovic, Dina and Marten, Jonathan and Musani, Solomon K and Li, Changwei and Bentley, Amy R and Brown, Michael R and Schwander, Karen and Richard, Melissa A and Noordam, Raymond and Aschard, Hugues and Bartz, Traci M and Bielak, Lawrence F and Dorajoo, Rajkumar and Fisher, Virginia and Hartwig, Fernando P and Horimoto, Andrea R. V.R and Lohman, Kurt K and Manning, Alisa K and Rankinen, Tuomo and Smith, Albert V and Tajuddin, Salman M and Wojczynski, Mary K and Alver, Maris and Boissel, Mathilde and Cai, Qiuyin and Campbell, Archie and Chai, Jin Fang and Chen, Xu and Divers, Jasmin and Gao, Chuan and Goel, Anuj and Hagemeijer, Yanick and Harris, Sarah E and He, Meian and Hsu, Fang-Chi and Jackson, Anne U and Kähönen, Mika and Kasturiratne, Anuradhani and Komulainen, Pirjo and Kühnel, Brigitte and Laguzzi, Federica and Luan, Jian'An and Matoba, Nana and Nolte, Ilja M and Padmanabhan, Sandosh and Riaz, Muhammad and Rueedi, Rico and Robino, Antonietta and Said, M. Abdullah and Scott, Robert A and Sofer, Tamar and Stančáková, Alena and Takeuchi, Fumihiko and Tayo, Bamidele O and Van Der Most, Peter J and Varga, Tibor V and Vitart, Veronique and Wang, Yajuan and Ware, Erin B and Warren, Helen R and Weiss, Stefan and Wen, Wanqing and Yanek, Lisa R and Zhang, Weihua and Zhao, Jing Hua and Afaq, Saima and Amin, Najaf and Amini, Marzyeh and Arking, Dan E and Aung, Tin and Boerwinkle, Eric and Borecki, Ingrid and Broeckel, Ulrich and Brown, Morris and Brumat, Marco and Burke, Gregory L and Canouil, Mickaël and Chakravarti, Aravinda and Charumathi, Sabanayagam and Chen, Yii-Der Ida and Connell, John M and Correa, Adolfo and De Las Fuentes, Lisa and De Mutsert, Renée and De Silva, H. Janaka and Deng, Xuan and Ding, Jingzhong and Duan, Qing and Eaton, Charles B and Ehret, Georg and ... and InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Näringsforskning and Umeå universitet
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, pp. e0198166 - e0198166
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation... 
COMMON VARIANTS | ENVIRONMENT INTERACTION | METAANALYSIS | PTP4A1-PHF3-EYS VARIANTS | TRANSCRIPTION FACTOR GATA4 | MULTIDISCIPLINARY SCIENCES | RISK | LOCI | FUNCTIONAL VARIATION | GENOME-WIDE ASSOCIATION | DEPENDENCE | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Blood Pressure - genetics | Humans | Middle Aged | Male | Continental Population Groups - genetics | Gene-Environment Interaction | Alcohol Drinking - genetics | Young Adult | Alcohol Drinking - epidemiology | Pedigree | Adolescent | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Hypertension - epidemiology | Hypertension - genetics | Genetic Predisposition to Disease - epidemiology | Continental Population Groups - statistics & numerical data | Cohort Studies | Genome-wide association studies | Usage | Influence | Blood pressure | Genetic aspects | Diagnosis | Drinking of alcoholic beverages | Health aspects | Risk factors | Hypertension | Consumption | Health care | Medical research | Genes | Genomics | Alcohol | Genomes | Preventive medicine | Gene expression | Epidemiology | Loci | Blood | Genetic effects | Correlation analysis | Replication | Genetics | Bioinformatics | Public health | Index Medicus | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Hälsovetenskaper | Klinisk medicin | Kardiologi | Clinical Medicine | Medical Genetics | Medicinsk genetik | Näringslära | Cardiac and Cardiovascular Systems | Medicinska och farmaceutiska grundvetenskaper | Nutrition and Dietetics | Health Sciences
Journal Article
Circulation, ISSN 0009-7322, 08/2015, Volume 132, Issue 7, pp. 586 - 594
BACKGROUND—High intake of polyunsaturated fatty acids (PUFAs) may reduce the risk of cardiovascular disease (CVD) and mortality. Large, prospective studies... 
biological markers | cohort studies | mortality | epidemiology | cardiovascular diseases | fatty acids | RANDOMIZED CONTROLLED-TRIALS | CARDIAC & CARDIOVASCULAR SYSTEMS | DIETARY-FAT | LONG-CHAIN OMEGA-3-FATTY-ACIDS | MYOCARDIAL-INFARCTION | SERUM CHOLESTERYL ESTERS | DOCOSAHEXAENOIC ACID | MIDDLE-AGED ADULTS | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | ALPHA-LINOLENIC ACID | ADIPOSE-TISSUE | Blood Glucose - analysis | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Mortality | Risk Factors | Proportional Hazards Models | Male | Biomarkers - blood | Cholesterol Esters - chemistry | Sweden - epidemiology | Cholesterol Esters - blood | Cardiotonic Agents | Fatty Acids, Unsaturated - blood | Dietary Fats | Lipids - blood | Fish Oils | Sex Factors | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Surveys and Questionnaires | Plant Oils | Recommended Dietary Allowances | Unsaturated fatty acids | Analysis | Patient outcomes | Biological markers | Cardiovascular diseases | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Hälsovetenskaper | Klinisk medicin | Kardiologi | Näringslära | Clinical Medicine | Cardiac and Cardiovascular Systems | Nutrition and Dietetics | Health Sciences
Journal Article
by Marklund, Matti and Wu, Jason H.Y and Imamura, Fumiaki and Del Gobbo, Liana C and Fretts, Amanda and de Goede, Janette and Shi, Peilin and Tintle, Nathan and Wennberg, Maria and Aslibekyan, Stella and Chen, Tzu-An and de Oliveira Otto, Marcia C and Hirakawa, Yoichiro and Eriksen, Helle Højmark and Kröger, Janine and Laguzzi, Federica and Lankinen, Maria and Murphy, Rachel A and Prem, Kiesha and Samieri, Cécilia and Virtanen, Jyrki and Wood, Alexis C and Wong, Kerry and Yang, Wei-Sin and Zhou, Xia and Baylin, Ana and Boer, Jolanda M.A and Brouwer, Ingeborg A and Campos, Hannia and Chaves, Paulo H M and Chien, Kuo-Liong and de Faire, Ulf and Djoussé, Luc and Eiriksdottir, Gudny and El-Abbadi, Naglaa and Forouhi, Nita G and Michael Gaziano, J and Geleijnse, Johanna M and Gigante, Bruna and Giles, Graham and Guallar, Eliseo and Gudnason, Vilmundur and Harris, Tamara and Harris, William S and Helmer, Catherine and Hellenius, Mai-Lis and Hodge, Allison and Hu, Frank B and Jacques, Paul F and Jansson, Jan-Håkan and Kalsbeek, Anya and Khaw, Kay-Tee and Koh, Woon-Puay and Laakso, Markku and Leander, Karin and Lin, Hung-Ju and Lind, Lars and Luben, Robert and Luo, Juhua and McKnight, Barbara and Mursu, Jaakko and Ninomiya, Toshiharu and Overvad, Kim and Psaty, Bruce M and Rimm, Eric and Schulze, Matthias B and Siscovick, David and Skjelbo Nielsen, Michael and Smith, Albert V and Steffen, Brian T and Steffen, Lyn and Sun, Qi and Sundström, Johan and Tsai, Michael Y and Tunstall-Pedoe, Hugh and Uusitupa, Matti I J and van Dam, Rob M and Veenstra, Jenna and Monique Verschuren, W.M and Wareham, Nick and Willett, Walter and Woodward, Mark and Yuan, Jian-Min and Micha, Renata and Lemaitre, Rozenn N and Mozaffarian, Dariush and Risérus, Ulf and Cohorts Heart Aging Res Genomic Ep and For the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE)
Circulation, ISSN 0009-7322, 05/2019, Volume 139, Issue 21, pp. 2422 - 2436
Journal Article
by de Vries, Paul S and Brown, Michael R and Bentley, Amy R and Sung, Yun J and Winkler, Thomas W and Ntalla, Ioanna and Schwander, Karen and Kraja, Aldi T and Guo, Xiuqing and Franceschini, Nora and Cheng, Ching-Yu and Sim, Xueling and Vojinovic, Dina and Huffman, Jennifer E and Musani, Solomon K and Li, Changwei and Feitosa, Mary F and Richard, Melissa A and Noordam, Raymond and Aschard, Hugues and Bartz, Traci M and Bielak, Lawrence F and Deng, Xuan and Dorajoo, Rajkumar and Lohman, Kurt K and Manning, Alisa K and Rankinen, Tuomo and Smith, Albert V and Tajuddin, Salman M and Evangelou, Evangelos and Graff, Mariaelisa and Alver, Maris and Boissel, Mathilde and Chai, Jin Fang and Chen, Xu and Divers, Jasmin and Gandin, Ilaria and Gao, Chuan and Goel, Anuj and Hagemeijer, Yanick and Harris, Sarah E and Hartwig, Fernando P and He, Meian and Horimoto, Andrea R V R and Hsu, Fang-Chi and Jackson, Anne U and Kasturiratne, Anuradhani and Komulainen, Pirjo and Kühnel, Brigitte and Laguzzi, Federica and Lee, Joseph H and Luan, Jian'an and Lyytikäinen, Leo-Pekka and Matoba, Nana and Nolte, Ilja M and Pietzner, Maik and Riaz, Muhammad and Said, M Abdullah and Scott, Robert A and Sofer, Tamar and Stančáková, Alena and Takeuchi, Fumihiko and Tayo, Bamidele O and van der Most, Peter J and Varga, Tibor V and Wang, Yajuan and Ware, Erin B and Wen, Wanqing and Yanek, Lisa R and Zhang, Weihua and Zhao, Jing Hua and Afaq, Saima and Amin, Najaf and Amini, Marzyeh and Arking, Dan E and Aung, Tin and Ballantyne, Christie and Boerwinkle, Eric and Broeckel, Ulrich and Campbell, Archie and Canouil, Mickaël and Charumathi, Sabanayagam and Chen, Yii-Der Ida and Connell, John M and de Faire, Ulf and de Las Fuentes, Lisa and de Mutsert, Renée and de Silva, H Janaka and Ding, Jingzhong and Dominiczak, Anna F and Duan, Qing and Eaton, Charles B and Eppinga, Ruben N and Faul, Jessica D and Fisher, Virginia and Forrester, Terrence and Franco, Oscar H and Friedlander, Yechiel and Ghanbari, Mohsen and Giulianini, Franco and ... and LifeLines Cohort Study Grp and InterAct Consortium and Lifelines Cohort, Groningen, The Netherlands (Lifelines Cohort Study)
American journal of epidemiology, ISSN 0002-9262, 06/2019, Volume 188, Issue 6, pp. 1033 - 1054
A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been... 
lipids | gene-environment interactions | gene-lifestyle interactions | cholesterol | triglycerides | alcohol consumption | genome-wide association studies | METAANALYSIS | BLOOD-LIPIDS | LOW-FREQUENCY | VEGF-B | INDIVIDUALS | DENSITY-LIPOPROTEIN CHOLESTEROL | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PLASMA | HDL CHOLESTEROL | CORONARY-HEART-DISEASE | CONSUMPTION
Journal Article