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PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e74538
The primary cause of death from breast cancer is the progressive growth of tumors and resistance to conventional therapies. It is currently believed that... 
MULTIDISCIPLINARY SCIENCES | RESISTANCE | STEM/PROGENITOR CELLS | LEUKEMIA | EXPRESSION | IN-VITRO PROPAGATION | BRAIN-TUMORS | REVEALS | Small Molecule Libraries - pharmacology | Neoplastic Stem Cells - drug effects | Humans | Spheroids, Cellular - pathology | Antineoplastic Agents - therapeutic use | Side-Population Cells - drug effects | Niclosamide - pharmacology | Side-Population Cells - metabolism | Neoplastic Stem Cells - pathology | Female | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | Drug Evaluation, Preclinical | Cell Separation | Mice, SCID | Breast Neoplasms - drug therapy | Side-Population Cells - pathology | Animals | High-Throughput Screening Assays | Signal Transduction - drug effects | Breast Neoplasms - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Niclosamide - therapeutic use | Drug Screening Assays, Antitumor | Drugs | Relapse | Stem cells | Antiparasitic agents | Product/Service Evaluations | Transplantation | Breast cancer | Diagnosis | Diseases | Cancer | Flow cytometry | Dehydrogenases | Laboratories | Oct-4 protein | Clinical trials | Niclosamide | Metastasis | Drug screening | Cancer therapies | Cell surface | Population | Growth factors | Medical research | Gynecology | Tumorigenicity | Tumor cell lines | Obstetrics | Spheroids | Screening | Hypotheses | Chemotherapy | Epigenetics | Breast | In vivo methods and tests | Surface markers | Tumors | Apoptosis
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2017, Volume 127, Issue 8, pp. 2982 - 2997
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0182166 - e0182166
Pyruvate kinase M2 (PKM2) regulates glycolysis and oxidative phosphorylation; however, the role of PKM2 in ovarian cancer remains largely unknown. We... 
APOPTOSIS | SHIKONIN | ENERGY | METABOLISM | STATISTICS | MULTIDISCIPLINARY SCIENCES | ISOFORM | ANTITUMOR-ACTIVITY | TUMOR-GROWTH | CELL | DERIVATIVES | Immunohistochemistry | Prognosis | Tissue Array Analysis | Humans | Ovarian Neoplasms - pathology | Positron-Emission Tomography | Female | Ovarian Neoplasms - drug therapy | Cell Survival - drug effects | Pyruvate Kinase - metabolism | Ovarian Neoplasms - diagnosis | Lactic Acid - metabolism | Biomarkers - analysis | Enzyme Inhibitors - pharmacology | Naphthoquinones - therapeutic use | Naphthoquinones - pharmacology | Mice, SCID | Enzyme Inhibitors - therapeutic use | Ovarian Neoplasms - enzymology | Xenograft Model Antitumor Assays | Disease-Free Survival | Pyruvate Kinase - antagonists & inhibitors | Animals | Cell Line, Tumor | Glucose - metabolism | Genetic aspects | Research | Pyruvate kinase | Ovarian cancer | Phosphorylation | Ovarian carcinoma | Laboratories | Toxicity | Pathogenesis | Physicians | Clinical trials | Acidification | Pyruvic acid | Malignancy | Multivariate analysis | Kinases | Confidence intervals | Shikonin | Xenografts | Cell cycle | Inhibition | Enzymes | Medical research | Adenosine | Gynecology | Oxygen consumption | Breast cancer | Metabolism | Patients | Obstetrics | Medicine | Studies | Hospitals | Inhibitors | Oxidative phosphorylation | Stem cells | Epigenetics | Glycolysis | Cell migration | Cancer | Apoptosis | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2017, Volume 140, Issue 5, pp. 1119 - 1133
The ongoing Triage and Risk Assessment of Cervical Precancer by Epigenetic Biomarker (TRACE) prospective, multicenter study aimed to provide a clinical... 
cervical cancer | high‐risk HPV | POU4F3 biomarker | epigenetics | host gene methylation | high-risk HPV | DNA METHYLATION | GUIDELINES | PREVENTION | FOLLOW-UP | TERMINOLOGY | HUMAN-PAPILLOMAVIRUS | CYTOLOGY | COLPOSCOPY | PATHOLOGY | ONCOLOGY | SCREENING-TESTS | DNA Probes, HPV | Prospective Studies | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Uterine Cervical Dysplasia - metabolism | DNA, Viral - analysis | Precancerous Conditions - metabolism | Transcription Factor Brn-3C - analysis | Biomarkers, Tumor | Young Adult | DNA Methylation | Precancerous Conditions - virology | Uterine Cervical Dysplasia - virology | Sensitivity and Specificity | Transcription Factor Brn-3C - genetics | Adult | Female | Papillomavirus Infections - virology | Triage | Real-Time Polymerase Chain Reaction | Promoter Regions, Genetic | Reproducibility of Results | Cervical Intraepithelial Neoplasia - chemistry | Hungary - epidemiology | Carcinoma, Squamous Cell - chemistry | Papillomaviridae - isolation & purification | Homeodomain Proteins - genetics | Cervical Intraepithelial Neoplasia - virology | Homeodomain Proteins - analysis | Papillomavirus Infections - metabolism | Adolescent | Biomarkers | Uterine Cervical Neoplasms - virology | Aged | Uterine Cervical Neoplasms - chemistry | Clinical trials | Epigenetic inheritance | Methylation | Papillomavirus infections | Cervical cancer | Human papillomavirus | Cellular biology | DNA methylation | Epigenetics | Medical screening | Deoxyribonucleic acid--DNA
Journal Article
Cancer Research, ISSN 0008-5472, 06/2008, Volume 68, Issue 11, pp. 4311 - 4320
The objective of this study was to identify and characterize a self-renewing subpopulation of human ovarian tumor cells (ovarian cancer-initiating cells,... 
PROGENITOR CELLS | SURFACE EPITHELIUM | STEM-CELLS | SUBPOPULATION | ONCOLOGY | BIOLOGY | RESISTANCE | EXPRESSION | CARCINOMA | IN-VITRO PROPAGATION | PACLITAXEL | Cell Separation | Humans | Fluorescent Antibody Technique | Ovarian Neoplasms - pathology | Neoplastic Stem Cells - pathology | Female | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2018, Volume 143, Issue 2, pp. 355 - 367
Mucinous type of epithelial ovarian cancer (MuOC) is a unique subtype with a poor survival outcome in recurrent and advanced stages. The role of type‐specific... 
proteasome inhibitors | mucinous ovarian carcinoma | methylation profiles | functional genetic interactions | PSMB8 | STEM-CELLS | DNA METHYLATION | RAS | SELF-RENEWAL | LARGE GENE LISTS | CANCER | TUMORS | BIOMARKERS | ONCOLOGY | SIGNALING PATHWAY | BORDERLINE | Gastrointestinal Neoplasms - genetics | Gastrointestinal Neoplasms - drug therapy | Humans | Cystadenoma, Mucinous - metabolism | Ovarian Neoplasms - genetics | DNA Methylation | Carcinoma, Ovarian Epithelial - drug therapy | Epigenomics - methods | Female | Ovarian Neoplasms - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Adenocarcinoma, Mucinous - drug therapy | Ovarian Neoplasms - drug therapy | Gastrointestinal Neoplasms - metabolism | Carcinoma, Ovarian Epithelial - genetics | Cell Survival - drug effects | Cystadenoma, Mucinous - genetics | Proteasome Inhibitors - pharmacology | Carcinoma, Ovarian Epithelial - metabolism | Cystadenoma, Mucinous - drug therapy | Proteasome Endopeptidase Complex - genetics | Adenocarcinoma, Mucinous - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Adenocarcinoma, Mucinous - genetics | Proteasome Endopeptidase Complex - metabolism | Oligopeptides - pharmacology | Cluster Analysis | Immunohistochemistry | Cellular proteins | Corticosteroids | Carcinoma | Proteolysis | Analysis | Colorectal cancer | Methylation | Ovarian cancer | Cancer | Adenocarcinoma | Cluster analysis | Ovarian carcinoma | Glucocorticoids | Genes | Staining | Nuclei (nuclear physics) | Adenoma | Nuclei | Proteins | Network analysis | Genetic analysis | DNA methylation | Uncertainty analysis | Deoxyribonucleic acid--DNA | Stomach | Clustering | Proteasome inhibitors | Inhibitors | Transport | Tumors | Cancer Genetics and Epigenetics
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e41060
Background: Despite of the trend that the application of DNA methylation as a biomarker for cancer detection is promising, clinically applicable genes are few.... 
EPIGENETICS | HYPERMETHYLATION | TUMOR-SUPPRESSOR REGION | ABNORMALITIES | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | GENES | MARKERS | HUMAN-PAPILLOMAVIRUS | WIDE | CANCER | Biomarkers - metabolism | Kruppel-Like Transcription Factors - biosynthesis | Promoter Regions, Genetic | Zinc Fingers | Humans | Gene Expression Regulation, Neoplastic | 3',5'-Cyclic-AMP Phosphodiesterases - genetics | Polymerase Chain Reaction - methods | DNA Methylation | 3',5'-Cyclic-AMP Phosphodiesterases - biosynthesis | Uterine Cervical Neoplasms - metabolism | Tumor Suppressor Proteins - genetics | CpG Islands | Female | ROC Curve | HeLa Cells | Tumor Suppressor Proteins - biosynthesis | Kruppel-Like Transcription Factors - genetics | Immunohistochemistry | Sulfites | Analysis | Genes | DNA | Genetic aspects | DNA binding proteins | Diagnosis | Methylation | Cervical cancer | Tumors | Cancer | Bisulfite | Immunoprecipitation | Laboratories | Genomics | Leukemia | Lung cancer | Genomes | Tissues | Medical diagnosis | Neoplasms | Scraping | Confidence intervals | Human papillomavirus | DNA methylation | Tiling | Life sciences | Cervical carcinoma | Zinc finger proteins | Lesions | Informatics | Deoxyribonucleic acid--DNA | Gynecology | Interdisciplinary aspects | Gene expression | Medical screening | Cervix | Bladder cancer | Obstetrics | Zinc | Screening | Hospitals | DNA microarrays | Stem cells | Epigenetics | Biomarkers | Deoxyribonucleic acid
Journal Article
Journal Article