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Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 850 - 858
The success of antitumor immune responses depends on the infiltration of solid tumors by effector T cells, a process guided by chemokines. Here we show that in... 
CD26 EXPRESSION | CELLS | CXCL10 | CHEMOKINE ACTIVITY | IN-VIVO | RECEPTOR | IMMUNOLOGY | CD26/DIPEPTIDYL PEPTIDASE-IV | PROTEINS | CANCER | POSTTRANSLATIONAL MODIFICATION | Dipeptidyl Peptidase 4 - metabolism | Immunotherapy - methods | Male | Adoptive Transfer | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Cell Movement - immunology | Flow Cytometry | Lymphocytes - immunology | Neoplasms, Experimental - immunology | Chemokine CXCL10 - immunology | Neoplasms, Experimental - genetics | Female | Sitagliptin Phosphate | Dipeptidyl Peptidase 4 - immunology | Chemokines - immunology | Lymphocytes - metabolism | Receptors, CXCR3 - metabolism | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Dipeptidyl Peptidase 4 - genetics | Mice, Transgenic | Mice, Knockout | Triazoles - pharmacology | Cell Movement - drug effects | Animals | Receptors, CXCR3 - immunology | Cell Line, Tumor | Chemokines - metabolism | Mice, Inbred BALB C | Pyrazines - pharmacology | Chemokine CXCL10 - metabolism | Care and treatment | Usage | Immunotherapy | Development and progression | Inflammation | Health aspects | Chemokines | Tumors | Neoplasms, Experimental/genetics | Immunotherapy/methods | Cell Movement/drug effects | Neoplasms, Experimental/therapy | Lymphocytes/metabolism | Lymphocytes/immunology | Dipeptidyl Peptidase 4/genetics | Life Sciences | Chemokine CXCL10/immunology | Immunology | Pyrazines/pharmacology | Dipeptidyl Peptidase 4/immunology | Dipeptidyl-Peptidase IV Inhibitors/pharmacology | Chemokines/metabolism | Receptors, CXCR3/immunology | Receptors, CXCR3/metabolism | Neoplasms, Experimental/immunology | Triazoles/pharmacology | Cell Movement/immunology | Chemokines/immunology | Dipeptidyl Peptidase 4/metabolism | Chemokine CXCL10/metabolism
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2012, Volume 188, Issue 7, pp. 2967 - 2971
The host response to Chikungunya virus is dependent on the direct action of type I IFN on infected nonhematopoietic cells. Prior studies have demonstrated that... 
Journal Article
Journal of Virology, ISSN 0022-538X, 10/2007, Volume 81, Issue 20, pp. 10838 - 10848
A FLAG epitope tag was substituted within variable loop 1 (V1), 2 (V2), or 4 (V4) of the gp120 envelope glycoprotein of simian immunodeficiency virus strain... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2012, Volume 188, Issue 7, pp. 2967 - 2971
The host response to Chikungunya virus is dependent on the direct action of type I IFN on infected nonhematopoietic cells. Prior studies have demonstrated that... 
PATHOGENESIS | VIRUS | PROTEIN | MODEL | IMMUNOLOGY | DISTINCT | Age Factors | Interferon Regulatory Factor-7 - genetics | Interferon Regulatory Factor-3 - genetics | Interferon Regulatory Factor-7 - physiology | Interferon-alpha - genetics | Bone Marrow Transplantation | Hematopoietic Stem Cells - virology | Fibroblasts - metabolism | Animals, Newborn | Chikungunya Fever | Fibroblasts - virology | Toll-Like Receptor 7 - genetics | Interferon-alpha - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 7 - deficiency | Hematopoietic Stem Cells - metabolism | Radiation Chimera | Alphavirus Infections - immunology | Chikungunya virus - growth & development | Chikungunya virus - immunology | Interferon Regulatory Factor-3 - physiology | Membrane Glycoproteins - genetics | Mice, Knockout | Host-Pathogen Interactions | Adaptor Proteins, Signal Transducing - physiology | Animals | Interferon Regulatory Factor-3 - deficiency | Myeloid Differentiation Factor 88 - deficiency | Interferon Regulatory Factor-7 - deficiency | Mice | Membrane Glycoproteins - deficiency | Interferon Regulatory Factor-7/deficiency | Toll-Like Receptor 7/genetics | Membrane Glycoproteins/genetics | Hematopoietic Stem Cells/metabolism | Myeloid Differentiation Factor 88/genetics | Life Sciences | Alphavirus Infections/immunology | Immunology | Fibroblasts/metabolism | Chikungunya virus/growth & development | Myeloid Differentiation Factor 88/deficiency | Toll-Like Receptor 7/deficiency | Interferon Regulatory Factor-3/physiology | Interferon Regulatory Factor-3/genetics | Interferon-alpha/biosynthesis | Adaptor Proteins, Signal Transducing/physiology | Hematopoietic Stem Cells/virology | Membrane Glycoproteins/deficiency | Interferon Regulatory Factor-3/deficiency | Chikungunya virus/immunology
Journal Article
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 06/2009, Volume 51, p. 1
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2014, Volume 61, Issue 4, pp. 770 - 776
Background & Aims HCV requires host lipid metabolism for replication, and apolipoproteins have been implicated in the response to treatment. Methods We... 
Gastroenterology and Hepatology | Quantitative trait loci | IL28B | Lipid metabolism | Hepatitis C virus | Apolipoproteins | PARTICLES | BETA-2-GLYCOPROTEIN-I | RIBAVIRIN | PEGYLATED INTERFERON-ALPHA | LIPOPROTEIN-LIPASE | HCV INFECTION | GENETIC-VARIATION | LOW-DENSITY | SERUM-LIPIDS | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Coinfection | Hepatitis C - drug therapy | Humans | Middle Aged | Male | Viral Load | beta 2-Glycoprotein I - blood | HIV Infections - immunology | Hepatitis C - immunology | Interleukins - genetics | Ribavirin - administration & dosage | Adult | Female | Hepacivirus - physiology | Hepatitis C - complications | Hepacivirus - drug effects | Virus Replication - drug effects | Hepatitis C - genetics | Treatment Outcome | Antiviral Agents - administration & dosage | Polyethylene Glycols - administration & dosage | Interferon-alpha - administration & dosage | beta 2-Glycoprotein I - genetics | HIV Infections - complications | HIV Infections - drug therapy | Hepatitis C - physiopathology | Aged | Polymorphism, Single Nucleotide | Genetic aspects | Health aspects | beta 2-Glycoprotein I/blood | Virus Replication/drug effects | HIV Infections/immunology | HIV Infections/drug therapy | Life Sciences | beta 2-Glycoprotein I/genetic | Immunology | Hepatitis C/complications Hepatitis | Polyethylene Glycols/administration & dosage | Interferon-alpha/administration & dosage | C/physiopathology Humans | Interleukins/genetics | Hepacivirus/physiology | C/drug therapy Hepatitis | C/immunology Hepatitis | HIV Infections/complications | Ribavirin/administration & dosage | Hepacivirus/drug effects | Antiviral Agents/administration & dosage | C/genetics Hepatitis
Journal Article
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | Immunology | Infectious Diseases | Immunology and Allergy | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
by Shen, H and Fridley, B.L and Song, H and Lawrenson, K and Cunningham, J.M and Ramus, S.J and Cicek, M.S and Tyrer, J and Stram, D and Larson, M.C and Kobel, M and Ziogas, A and Zheng, W and Yang, H.P and Wu, A.H and Wozniak, E.L and Ling Woo, Y and Winterhoff, B and Wik, E and Whittemore, A.S and Wentzensen, N and Palmieri Weber, R and Vitonis, A.F and Vincent, D and Vierkant, R.A and Vergote, I and Berg, D. Van den and Altena, A.M. van and Tworoger, S.S and Thompson, P.J and Tessier, D.C and Terry, K.L and Teo, S.H and Templeman, C and Stram, D.O and Southey, M.C and Sieh, W and Siddiqui, N and Shvetsov, Y.B and Shu, X.O and Shridhar, V and Wang-Gohrke, S and Severi, G and Schwaab, I and Salvesen, H.B and Rzepecka, I.K and Runnebaum, I.B and Rossing, M.A and Roiguez-Roiguez, L and Risch, H.A and Renner, S.P and Poole, E.M and Pike, M.C and Phelan, C.M and Pelttari, L.M and Pejovic, T and Paul, J and Orlow, I and Zawiah Omar, S and Olson, S.H and Odunsi, K and Nickels, S and Nevanlinna, H and Ness, R.B and Narod, S.A and Nakanishi, T and Moysich, K.B and Monteiro, A.N and Moes-Sosnowska, J and Modugno, F and Menon, U and McLaughlin, J.R and McGuire, V and Matsuo, K and Mat Adenan, N.A and Massuger, L.F.A.G and Lurie, G and Lundvall, L and Lubinski, J and Lissowska, J and Levine, D.A and Leminen, A and Lee, A.W and Le, N.D and Lambrechts, S and Lambrechts, D and Kupryjanczyk, J and Krakstad, C and Konecny, G.E and Kruger Kjaer, S and Kiemeney, L.A.L.M and Kelemen, L.E and Keeney, G.L and Karlan, B.Y and Karevan, R and Kalli, K.R and Kajiyama, H and Ji, B.T and Jensen, A and Jakubowska, A and ... and PRACTICAL Consortium and Australian Ovarian Canc Study Grp and Australian Canc Study and Australian Ovarian Cancer Study Group and Australian Cancer Study
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 1628
Journal Article