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The New England Journal of Medicine, ISSN 0028-4793, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MYOCARDIAL-INFARCTION | STATIN THERAPY | CLONAL HEMATOPOIESIS | INFLAMMATION | CARDIOVASCULAR-DISEASE | INTERLEUKIN-1-BETA INHIBITION | RISK | CORONARY-ARTERY-DISEASE | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Klinisk medicin | Clinical Medicine
Journal Article
by Drake, Thomas M and Cheung, Lok Ka and Gaba, Fortis and Glasbey, James and Griffiths, Nathan and Helliwell, Rebecca J and Huq, Tausif and Khaw, Rachel and Mayes, Jonathan and Khan, Saif and Rafiq, Nasir and Woin, Evelina and Fitzgerald, J Edward and Harrison, Ewen M and Nepogodiev, Dmitri and Drake, TM and Drake, Thomas M and Glasbey, James and Bath, Mike and Borakati, Aditya and Burke, Joshua and Claireaux, Henry and Deekonda, Praveena and Gundogan, Buket and Joyce, Holly and Kamarajah, Sivesh and Khatri, Chetan and Kong, Chia and McLean, Kenneth A and Mcnamee, Lisa and Mohan, Midhun and Woin, Evelina and Fitzgerald, J Edward and Bhangu, Aneel and Harrison, Ewen M and Nepogodiev, Dmitri and Arulkumaran, Nishkantha and Bell, Samira and Duthie, Fiona and Hughes, Jeremy and Prowle, John and Richards, Toby and Dynes, K and Patel, P and Wigley, C and Suresh, R and Shaw, A and Klimach, S and Jull, P and Evans, D and Preece, R and Ibrahim, I and Manikavasagar, V and Brown, F S and Deekonda, P and Teo, R and Sim, D P Y and Borakati, A and Logan, A E and Barai, I and Amin, H and Suresh, S and Sethi, R and Bolton, W and Corbridge, O and Horne, L and Attalla, M and Morley, R and Hoskins, T and McAllister, R and Lee, S and Dennis, Y and Nixon, G and Heywood, E and Wilson, H and Ng, L and Samaraweera, S and Mills, A and Doherty, C and Woin, E and Belchos, J and Phan, V and Chouari, T and Gardner, T and Goergen, N and Hayes, J D B and MacLeod, C S and McCormack, R and McKinley, A and McKinstry, S and Milligan, W and Ooi, L and Rafiq, N M and Sammut, T and Sinclair, E and Smith, M and Baker, C and Boulton, A P R and Collins, J and Copley, H C and ... and STARSurg Collaborative
Anaesthesia, ISSN 0003-2409, 10/2018, Volume 73, Issue 10, pp. 1214 - 1222
Summary The peri‐operative use of angiotensin‐converting enzyme inhibitors or angiotensin‐2 receptor blockers is thought to be associated with an increased... 
postoperative complications | acute kidney injury | angiotensin‐converting enzyme inhibitors | angiotensin II receptor blockers | angiotensin-converting enzyme inhibitors | RISK | ANESTHESIOLOGY | DIURETICS | Prospective Studies | Humans | Middle Aged | Elective Surgical Procedures - adverse effects | Postoperative Complications - prevention & control | Male | Angiotensin-Converting Enzyme Inhibitors - adverse effects | Aged, 80 and over | Female | Acute Kidney Injury - chemically induced | Postoperative Complications - chemically induced | Drug Administration Schedule | Comorbidity | Risk Factors | Ireland - epidemiology | Postoperative Complications - epidemiology | Digestive System Surgical Procedures - adverse effects | Withholding Treatment | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Acute Kidney Injury - prevention & control | Perioperative Care - methods | Aged | Acute Kidney Injury - epidemiology | United Kingdom - epidemiology | Angiotensin Receptor Antagonists - administration & dosage | Angiotensin Receptor Antagonists - adverse effects | Heart | Enzymes | Kidneys | Heart surgery | Health risks | Risk reduction | Risk | Gastrointestinal tract | Patients | Matching | Injury prevention | Inhibitors | Enzyme inhibitors | Converting | Surgery | Gastrointestinal system | Angiotensin
Journal Article