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Pharmaceuticals (Basel, Switzerland), ISSN 1424-8247, 08/2019, Volume 12, Issue 3, p. 125
Iron deficiency is the most common nutritional disorder in the world. It is prevalent amongst patients with cardiovascular disease, in whom it is associated... 
hepcidin | cardiomyocyte | pulmonary arterial smooth muscle cells | iron | chronic heart failure | iron regulatory proteins | pulmonary arterial hypertension
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. SCI-21 - SCI-21
Abstract Ferroportin, the only known mammalian iron export protein, releases iron from the duodenum, reticuloendothelial system and liver, the sites of iron... 
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 03/2019, Volume 133, pp. 234 - 237
Heart disease is a common manifestation in conditions of iron imbalance. Normal heart function requires coupling of iron supply for oxidative phosphorylation... 
Heart | Ferroportin | Homeostasis | Iron | Hepcidin | OVERLOAD | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOMYOPATHY | PREVALENCE | FAILURE | DEFICIENCY | REGULATORY PROTEINS | ERYTHROFERRONE | ACUTE-PHASE | ENDOCRINOLOGY & METABOLISM | ANEMIA | Proteins | Physiological aspects | Iron industry | Heart diseases
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 09/2019, Volume 189, Issue 9, pp. 1814 - 1830
The liver secretes hepcidin (Hepc) into the bloodstream to reduce blood iron levels. Hepc accomplishes this by triggering degradation of the only known... 
Journal Article
Nature Protocols, ISSN 1754-2189, 2012, Volume 7, Issue 12, pp. 2112 - 2126
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 10/2017, Volume 123, Issue 4, p. 967
Iron is subject to tight homeostatic control in mammals. At the systemic level, iron homeostasis is controlled by the liver-derived hormone hepcidin acting on... 
Heart | Spleen | Oxygen | Liver | Homeostasis | Chemical reactions | Iron | Coronary artery disease | Proteins | Hypoxia | Chemical properties | Heart diseases | Hepcidin | Regulatory proteins
Journal Article
Heart, ISSN 1355-6037, 05/2019, Volume 105, Issue Suppl 6, p. A142
IntroductionIron deficiency augments hypoxic pulmonary arterial pressure in healthy individuals and exacerbates pulmonary arterial hypertension (PAH) in... 
Hypertension | Smooth muscle | Iron | Anemia
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2015, Volume 112, Issue 10, pp. 3164 - 3169
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2019, Volume 116, Issue 26, pp. 13122 - 13130
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 10/2017, Volume 123, Issue 4, pp. 967 - 973
Iron is subject to tight homeostatic control in mammals. At the systemic level, iron homeostasis is controlled by the liver-derived hormone hepcidin acting on... 
Ferroportin | Heart | Oxygen | Iron | Hepcidin | SPORT SCIENCES | hepcidin | PHYSIOLOGY | ferroportin | FAILURE | heart | HORMONE HEPCIDIN | DEFICIENCY | REGULATORY PROTEINS | ERYTHROFERRONE | ACUTE-PHASE | INFLAMMATION | HEPCIDIN SUPPRESSION | iron | FERRIC CARBOXYMALTOSE | ANEMIA | oxygen | Animals | Iron - metabolism | Homeostasis - physiology | Humans | Myocardium - metabolism | Oxygen - metabolism | Review
Journal Article
Experimental Eye Research, ISSN 0014-4835, 10/2019, Volume 187, p. 107728
Retinal iron accumulation has been implicated in the pathogenesis of age-related macular degeneration (AMD) and other neurodegenerative diseases. The retina... 
Ferroportin | Retina | Iron | Age-related macular degeneration (AMD) | Retinal vascular endothelium | Ferritin
Journal Article
Heart, ISSN 1355-6037, 06/2017, Volume 103, Issue Suppl 5, pp. A137 - A137
BackgroundIron deficiency and chronic heart failure are two of the most common disorders worldwide. Recent evidence has demonstrated that they are linked.... 
Journal Article