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Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2008, Volume 7, Issue 8, pp. 2348 - 2357
We previously reported that our novel compound 3β-hydroxy-17-(1 H -benzimidazole-1-yl)androsta-5,16-diene (VN/124-1) is a potent 17α-hydroxylase/17,20-lyase... 
CYP17 inhibitor/antiandrogen | prostate cancer prevention and inhibition | IN-VITRO | POTENTIAL AGENTS | LNCAP | GENE | MECHANISM | ONCOLOGY | TESTOSTERONE | STRATEGY | CELL-GROWTH | PROGRESSION | ADRENAL ANDROGENS
Journal Article
Expert Opinion on Drug Discovery, ISSN 1746-0441, 11/2009, Volume 4, Issue 11, pp. 1099 - 1111
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 5/2012, Volume 133, Issue 1, pp. 137 - 144
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. LB-340 - LB-340
Journal Article
Steroids, ISSN 0039-128X, 2011, Volume 76, Issue 12, pp. 1268 - 1279
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2005, Volume 48, Issue 8, pp. 2972 - 2984
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 51, pp. 88501 - 88516
The androgen receptor (AR) has long been the primary target for the treatment of prostate cancer (PC). Despite continuous efforts to block AR activity through... 
AR-V7 | CWR22Rv1 | Prostate cancer | Apoptosis | Unfolded protein response | REGULATES ANDROGEN RECEPTOR | BIP | apoptosis | ENDOPLASMIC-RETICULUM STRESS | CELL BIOLOGY | unfolded protein response | prostate cancer | ANTIANDROGEN | IN-VIVO | GROWTH | DEGRADATION | BINDING | XENOGRAFT MODEL | ABIRATERONE
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2008, Volume 16, Issue 6, pp. 3352 - 3360
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2009, Volume 52, Issue 22, pp. 7122 - 7131
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 07/2014, Volume 734, Issue 1, pp. 98 - 104
Journal Article