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PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0120995
Objective We aimed to identify a novel panel of biomarkers predicting renal function decline in type 2 diabetes, using biomarkers representing different... 
GLOMERULAR-FILTRATION-RATE | PLASMA | ENDOTHELIAL DYSFUNCTION | ALBUMINURIA | MICROALBUMINURIA | INFLAMMATION | MELLITUS | CHRONIC KIDNEY-DISEASE | NEPHROPATHY | PROGRESSION | YKL-40 LEVELS | MULTIDISCIPLINARY SCIENCES | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Bone Morphogenetic Proteins - blood | Diabetic Nephropathies - blood | Diabetic Nephropathies - diagnosis | Adipokines - blood | Chitinase-3-Like Protein 1 | Kidney - metabolism | Diabetic Nephropathies - physiopathology | Adult | Female | Renal Insufficiency, Chronic - diagnosis | Membrane Proteins - blood | Kidney - physiopathology | Natriuretic Peptide, C-Type - blood | Glomerular Filtration Rate | Receptors, Tumor Necrosis Factor, Type I - blood | Risk Factors | Biomarkers - blood | Genetic Markers | Intracellular Signaling Peptides and Proteins - blood | Chemokine CCL2 - blood | Renal Insufficiency, Chronic - physiopathology | Disease Progression | Protein-Tyrosine Kinases - blood | Renal Insufficiency, Chronic - blood | Diabetes Mellitus, Type 2 - diagnosis | Diabetes Mellitus, Type 2 - blood | Lectins - blood | Diabetes Mellitus, Type 2 - physiopathology | Outpatients | Matrix Metalloproteinases, Secreted - blood | Fibrosis | Aged | Connective Tissue Growth Factor - blood | Type 2 diabetes | Complications and side effects | Research | Kidney diseases | Diagnosis | Biological markers | Risk factors | Nephrology | Renal function | Risk | SOST protein | Angiogenesis | Pathways | Mathematical analysis | Data integration | Rodents | Mathematical models | Protein-tyrosine kinase | Tyrosine | Medical research | Internal medicine | Epidermal growth factor receptors | Diabetes mellitus | Health risks | Connective tissue growth factor | Pharmacology | Shrinkage | Patients | Studies | Nephropathy | Tumor necrosis factor | Pharmacy | Predictions | Biomarkers | Research design | Diabetes | Monocyte chemoattractant protein 1 | Kidney transplantation
Journal Article
BMJ, ISSN 0959-8138, 7/2011, Volume 343, Issue 7818, pp. 298 - 298
Objective To compare the effects on proteinuria and blood pressure of addition of dietary sodium restriction or angiotensin receptor blockade at maximum dose,... 
RESEARCH | Enzymes | Nephrology | Sodium | Internal medicine | Sodium restricted diets | Enzyme inhibition | Blood pressure | Dietary sodium | Angiotensin receptors | Proteinuria | ANTIPROTEINURIC EFFICACY | GLOMERULAR-FILTRATION-RATE | TERM ANTIHYPERTENSIVE TREATMENT | CARDIOVASCULAR-DISEASE | ACE-INHIBITION | CHRONIC KIDNEY-DISEASE | DIABETIC NEPHROPATHY | UMCG Approved | HYPERTENSIVE PATIENTS | CHRONIC-RENAL-FAILURE | ALDOSTERONE SYSTEM | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | RENAL HEMODYNAMICS | CARDIOVASCULAR RISK | PROGRESSION | Kidney Diseases - physiopathology | Valsartan | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Sodium Chloride, Dietary - administration & dosage | Male | Proteinuria - prevention & control | Lisinopril - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Hypertension - prevention & control | Female | Blood Pressure - drug effects | Blood Pressure - physiology | Kidney Diseases - complications | Drug Therapy, Combination | Double-Blind Method | Valine - analogs & derivatives | Treatment Outcome | Combined Modality Therapy | Hypertension - physiopathology | Proteinuria - physiopathology | Cross-Over Studies | Diet, Sodium-Restricted - methods | Tetrazoles - therapeutic use | Valine - therapeutic use | Patient Compliance | Chronic Disease
Journal Article
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 06/2015, Volume 10, Issue 6, pp. 1099 - 1099
Our opponents in this debate state that there are insufficient data to consider albuminuria as a valid target for therapy in patients with CKD. They base their... 
UROLOGY & NEPHROLOGY | Albuminuria - therapy | Renal Insufficiency, Chronic - therapy | Kidney - drug effects | Humans | Serum Albumin - metabolism | Urological Agents - therapeutic use | Controversies in Nephrology | albuminuria | renoprotection | CKD
Journal Article
Diabetes obesity & metabolism, ISSN 1462-8902, 05/2017, Volume 19, Issue 5, pp. 749 - 753
Journal Article
Journal Article
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 10/2017, Volume 12, Issue 10, pp. 1595 - 1600
Background and objectives: RRT and doubling of serum creatinine are considered the objective hard end points in nephrology intervention trials. Because both... 
SERUM CREATININE | CHOICE | DECISION | DISEASE | NEPHROLOGISTS | DIABETIC-NEPHROPATHY | OUTCOMES | IRBESARTAN | PROGRESSION | DECLINE | Creatinine | Nephrology | Diabetes mellitus, type 2 | Humans | Diabetic nephropathies | Tetrazoles | Linear models | Kidney | Glomerular filtration rate | Irbesartan | Losartan | Renal dialysis | Renal replacement therapy | Angiotensin II | Biphenyl compounds | GFR | UROLOGY & NEPHROLOGY | START | NEPHROPATHY | Up-Regulation | Angiotensin II Type 1 Receptor Blockers - adverse effects | Renal Insufficiency, Chronic - etiology | Diabetic Nephropathies - etiology | Health Status Indicators | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Biphenyl Compounds - adverse effects | Diabetic Nephropathies - drug therapy | Biphenyl Compounds - therapeutic use | Glomerular Filtration Rate - drug effects | Diabetic Nephropathies - physiopathology | Time Factors | Clinical Decision-Making | Endpoint Determination | Diabetes Mellitus, Type 2 - complications | Kidney - physiopathology | Kidney - drug effects | Risk Factors | Proportional Hazards Models | Linear Models | Treatment Outcome | Biomarkers - blood | Renal Insufficiency, Chronic - physiopathology | Disease Progression | Renal Insufficiency, Chronic - prevention & control | Diabetes Mellitus, Type 2 - physiopathology | Losartan - therapeutic use | Creatinine - blood | Losartan - adverse effects | Tetrazoles - therapeutic use | Clinical Trials as Topic - methods | Tetrazoles - adverse effects | Diabetes Mellitus, Type 2 - drug therapy | Health Status | Research Design | Renal Dialysis | irbesartan | Diabetic Nephropathies | glomerular filtration rate | Renal Replacement Therapy | Biphenyl Compounds | nephrology | kidney | creatinine | Diabetes Mellitus, Type 2 | Original | renal dialysis
Journal Article
Journal Article
American Journal of Kidney Diseases, ISSN 0272-6386, 2014, Volume 63, Issue 2, pp. 244 - 250
Journal Article