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American Journal of Physiology, ISSN 1040-0605, 08/2014, Volume 307, Issue 3, p. L273
  Severe bronchospasm refractory to β-agonists continues to cause significant morbidity and mortality in asthmatic patients. We questioned whether chloride... 
Calcium | Mortality | Rodents | Lung diseases | Smooth muscle | Morbidity
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2004, Volume 114, Issue 9, pp. 1184 - 1186
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2002, Volume 124, Issue 33, pp. 9678 - 9679
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2011, Volume 17, Issue 2, pp. 216 - 222
Journal Article
2012, 24th ed., ISBN 0808924370, 2 v. (xlii, 2569, 86 p.)
Since 1927, Goldman's Cecil Medicine has been the world's most influential internal medicine reference. Edited by Lee Goldman, MD and Andrew I. Schafer, MD,... 
Internal medicine
Book
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3202 - 3202
Abstract Introduction: Germinal Center Kinase (GCK) is an essential regulator of stress-activated MAPK core signaling pathways. Recent studies revealing the... 
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2009, Volume 29, Issue 25, pp. 8075 - 8086
Memory loss, synaptic dysfunction, and accumulation of amyloid beta-peptides (A beta) are major hallmarks of Alzheimer's disease (AD). Downregulation of the... 
NEURONAL GENES | SILDENAFIL | AVOIDANCE | SELECTIVE PDE5 INHIBITOR | NITRIC-OXIDE | CGMP | RAT HIPPOCAMPUS | MICE | MECHANISMS | DYSFUNCTION | NEUROSCIENCES | Immunohistochemistry | Memory - drug effects | Piperazines - administration & dosage | Phosphodiesterase 5 Inhibitors | Purines - administration & dosage | Sulfones - pharmacology | Sildenafil Citrate | Time Factors | Amyloid beta-Peptides - metabolism | Polymerase Chain Reaction | Spatial Behavior - drug effects | Synaptic Transmission - drug effects | Phosphorylation - drug effects | Piperazines - pharmacokinetics | Alzheimer Disease - psychology | Disease Models, Animal | Psychomotor Performance | Conditioning, Classical - drug effects | Phosphodiesterase Inhibitors - pharmacokinetics | Purines - pharmacology | Purines - pharmacokinetics | Injections, Intraperitoneal | Alzheimer Disease - drug therapy | Phosphodiesterase Inhibitors - pharmacology | Mice, Transgenic | Treatment Outcome | Sulfones - pharmacokinetics | Piperazines - pharmacology | Neuropsychological Tests | Phosphodiesterase Inhibitors - administration & dosage | Amyloid beta-Protein Precursor - genetics | Animals | Analysis of Variance | Cyclic GMP - metabolism | Alzheimer Disease - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Mice | Mutation | Sulfones - administration & dosage
Journal Article
by Ghinda, Diana and Chen, Suzan and Bedaiwy, Mahmoud and Jabri, Hussam and Alshardan, Mohammad and Taccone, Michael S and Lai, Carolyn and Rabski, Jessica and Tsai, Eve and Dedek, Annemarie and Xu, Jian and Tsai, Eve and Lombroso, Paul and Hildebrand, Mike and Mothe, Andrea and Tator, Charles H and Siladi, Andrew and Nally, Jaqueline and Stirling, David and Keller, Anastasia and Buckley, Christian and Shum-Siu, Alice and Magnuson, David and Rosenbaum, Benjamin P and Kelly, Michael L and Ahuja, Christopher and Ahuja, Christopher and Nori, Satoshi and Khazaei, Mohamad and Ahlfors, Jan-Eric and Liu, Yang and Wang, Jian and Fuehrmann, Tobias and Pakulska, Malgosia and Hettiaratchi, Marian H and Poon, Peter and Shoichet, Molly S and Fehlings, Michael G and Fehlings, Michael G and Fehlings, Michael G and Hazrati, Lili-Naz and Cherian, Leela and Nilewski, Lizanne and Tour, James M and Kent, Thomas A and Robertson, Claudia S and Wilde, Elisabeth and Newsome, Mary and Scheibel, Randall and Troyanskaya, Maya and Velez, Carmen and Wade, Benjamin and Drennon, Ann Marie and York, Gerald and Bigler, Erin and Abildskov, Tracy and Taylor, Brian and Jaramillo, Carlos and Eapen, Blessen and Belanger, Heather and Morey, Rajendra and Haswell, Courtney and Levin, Harvey and Hinds, Sidney and Walker, William and Walker, William and Kochunov, Peter and Jahanshad, Neda and Thompson, Paul and Tate, David and Statz, Jonathan and Goodrich, Jessica and Goforth, Cdr Carl and Tschiffely, Anna E and Arena, John D and Smith, Douglas H and Wolf, John A and Johnson, Victoria E and Rhodes, James and Friess, Stuart and Lee, Taylor and Lycke, Roy J and Jang, Ikbeom and Vike, Nicole L and Nauman, Eric A and Talavage, Thomas M and Rispoli, Joseph V and Alonso-Escalante, Jose and Fulton, William and Sodhi, Chhinder and Hackam, David J and Nasr, Isam W and Hubbard, W B and Joseph, Binoy and Spry, Malinda L and Vekaria, Hemendra J and Saatman, Kathryn and Sullivan, Patrick G and Sullivan, Patrick G and Vascak, Michal and ...
Journal of Neurotrauma, ISSN 0897-7151, 08/2018, Volume 35, Issue 16, pp. A-1 - A-285
[...]the vast majority of basic science pain research ends at target identification and validation in rodent models of chronic pain without confirmation in... 
Abstracts | Neurosciences | Keywords | Traumatic brain injury | Cytokines | Central nervous system | Inflammation | Gene expression | Trauma | Studies | Brain research | Hospitals | Pain | Rodents | Stem cells | DNA methylation | Biomarkers | Spinal cord injuries | Growth factors | Research centers | Proteins
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 08/2010, Volume 6, Issue 8, pp. 602 - 609
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2017, Volume 60, Issue 21, pp. 8858 - 8875
Phosphodiesterase 5 (PDE5) hydrolyzes cyclic guanosine monophosphate (cGMP) leading to increased levels of the cAMP response element binding protein (CREB), a... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2001, Volume 123, Issue 21, pp. 4928 - 4931
We adapted in two steps a deoxyribonucleotide-based aptamer to signal the recognition of cocaine:  an instability was engineered in one stem of a three-way... 
ANTIBODIES | RNA MOLECULES | SIGNALING APTAMERS | DNA APTAMER | RECOGNITION | CHEMISTRY, MULTIDISCIPLINARY | Cocaine - analysis | Fluorescent Dyes - chemistry | Deoxyribonucleotides - chemistry | Chemical detectors | Cocaine | Design and construction | Research
Journal Article
Science, ISSN 0036-8075, 4/2004, Volume 304, Issue 5668, pp. 292 - 296
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 11/2004, Volume 114, Issue 9, pp. 1184 - 1186
The creation of human embryonic stem cells through the destruction of a human embryo pits the value of a potential therapeutic tool against that of an early... 
MEDICINE, RESEARCH & EXPERIMENTAL | Cloning, Organism | Humans | Bioethics | Embryo Research | Tissue and Organ Procurement | Stem Cells - cytology | Research | Research Embryo Creation | Embryo, Mammalian - physiology | Fertilization in Vitro | Embryo, Mammalian - cytology | Models, Biological | Beginning of Human Life | Death | Review
Journal Article
ChemBioChem, ISSN 1439-4227, 10/2015, Volume 16, Issue 15, pp. 2205 - 2215
Journal Article