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PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149405 - e0149405
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 14, Issue 3, pp. 263 - 273
Several hypotheses have been proposed to explain how antiangiogenic drugs enhance the treatment efficacy of cytotoxic chemotherapy, including impairing the... 
CELLCYCLE | BREAST-CANCER | LUNG-CANCER | RECRUITMENT | THERAPY | ONCOLOGY | VEGF | CHEMOKINE | GROWTH-FACTOR | TUMOR ANGIOGENESIS | NEOVASCULARIZATION | METRONOMIC CHEMOTHERAPY | CELL BIOLOGY | Paclitaxel - pharmacology | Apoptosis - drug effects | Humans | Melanoma, Experimental - drug therapy | Antibodies, Monoclonal - therapeutic use | Deoxycytidine - pharmacology | Antineoplastic Agents - therapeutic use | Deoxycytidine - therapeutic use | Neoplasms - blood | Angiogenesis Inhibitors - therapeutic use | Bone Marrow Cells - drug effects | Female | Antineoplastic Agents - pharmacology | Drug Therapy, Combination | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Vascular Endothelial Growth Factor A - blood | Angiogenesis Inhibitors - pharmacology | Melanoma, Experimental - pathology | Carcinoma, Lewis Lung - blood | Breast Neoplasms - drug therapy | Paclitaxel - therapeutic use | Carcinoma, Lewis Lung - drug therapy | Neoplasms - drug therapy | Animals | Tumor Burden - drug effects | Breast Neoplasms - pathology | Chemokine CXCL12 - blood | Breast Neoplasms - blood | Carcinoma, Lewis Lung - pathology | Stem Cells - drug effects | Stem Cells - pathology | Cell Proliferation - drug effects | Melanoma, Experimental - blood | Mice | Mice, Inbred BALB C | Endothelial Cells - pathology | Neoplasms - pathology | Deoxycytidine - analogs & derivatives | Endothelial Cells - drug effects | Antimitotic agents | Chemotherapy | Antineoplastic agents | Antitank weapons | Cancer | Tumors | Endothelium | Index Medicus
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2017, Volume 23, Issue 18, pp. 5406 - 5415
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2011, Volume 17, Issue 18, pp. 6071 - 6082
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2017, Volume 76, pp. 144 - 151
Abstract Purpose In tumours with wild-type TP53 , the tumour-suppressive function of p53 is frequently inhibited by HDM2. This phase I, dose-escalating study... 
Hematology, Oncology and Palliative Medicine | HDM2 | De-differentiated liposarcoma | Pharmacodynamics | Solid tumours | MDM2 | Pharmacokinetics | SAR405838 | p53 | LIPOSARCOMA | P53 PATHWAY | TRIAL | AMPLIFICATION | DATABASE | ONCOLOGY | MDM2 ANTAGONIST | MUTATION | INHIBITOR | Lung Neoplasms - drug therapy | Skin Neoplasms - drug therapy | Nausea - chemically induced | Gastrointestinal Neoplasms - drug therapy | Humans | Middle Aged | Spiro Compounds - administration & dosage | Lung Neoplasms - pathology | Male | Fatigue - chemically induced | Antineoplastic Agents - administration & dosage | Spiro Compounds - adverse effects | Indoles - administration & dosage | Dose-Response Relationship, Drug | Young Adult | Gastrointestinal Neoplasms - pathology | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - pathology | Skin Neoplasms - pathology | Liposarcoma - drug therapy | Liposarcoma - pathology | Thrombocytopenia - chemically induced | Melanoma - pathology | Spiro Compounds - pharmacokinetics | Neoplasms - drug therapy | Vomiting - chemically induced | Maximum Tolerated Dose | Indoles - adverse effects | Melanoma - drug therapy | Anorexia - chemically induced | Indoles - pharmacokinetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasms - pathology | Tumor proteins | Care and treatment | Tumors | Cytokines | Toxicity | p53 Protein | Nausea | Pharmacology | Patients | Metastases | Minimum inhibitory concentration | Liposarcoma | Biomarkers | Bioindicators | Safety | Solid tumors | Mutation | Index Medicus
Journal Article
Journal Article
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 05/2010, Volume 9, Issue 9, pp. 743 - 748
Journal Article
Journal Article