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British Journal of Pharmacology, ISSN 0007-1188, 11/2018, Volume 175, Issue 21, pp. 4005 - 4008
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2014, Volume 171, Issue 2, pp. 281 - 282
Journal Article
Journal of Chemical Theory and Computation, ISSN 1549-9618, 01/2018, Volume 14, Issue 1, p. 426
Motivated by the extremely high computing costs associated with estimates of free energies for biological systems using molecular simulations, we further the... 
Peptides | Computer simulation | Propagation | Computing costs | Chains | Estimates | Molecular chains | Proteins | Confidence intervals | Molecular conformation | Algorithms | Microprocessors | Discretization | Run time (computers) | Graphical representations | Binding sites | Lysozyme | Estimators
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2013, Volume 169, Issue 2, pp. 353 - 356
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2008, Volume 117, Issue 2, pp. 232 - 243
Muscarinic acetylcholine receptors (mAChRs) are widely expressed in the CNS where they control a variety of neuronal functions. Due to their roles in a number... 
Parkinson's disease | mAChR | Schizophrenia | CNS | Drug dependence | Muscarinic receptors | Alzheimer's disease | AFFINITY AGONIST BINDING | ALZHEIMERS-DISEASE | schizophrenia | AMYLOID PRECURSOR PROTEIN | SUBSTANTIA-NIGRA | drug dependence | PEDUNCULOPONTINE TEGMENTAL NUCLEUS | muscarinic receptors | EXPERIMENTAL CHOLINERGIC DENERVATION | M-1 RECEPTOR | A-BETA | PHARMACOLOGY & PHARMACY | HAMSTER OVARY-M1 CELLS | NIGRA PARS COMPACTA | Central Nervous System Agents - therapeutic use | Schizophrenia - metabolism | Antiparkinson Agents - pharmacology | Central Nervous System - metabolism | Muscarinic Agonists - pharmacology | Humans | Muscarinic Agonists - therapeutic use | Receptor, Muscarinic M2 - drug effects | Receptors, Muscarinic - metabolism | Parkinson Disease - drug therapy | Muscarinic Antagonists - therapeutic use | Receptors, Muscarinic - drug effects | Receptor, Muscarinic M1 - drug effects | Muscarinic Antagonists - pharmacology | Parkinson Disease - metabolism | Substance-Related Disorders - metabolism | Receptor, Muscarinic M2 - metabolism | Alzheimer Disease - drug therapy | Receptor, Muscarinic M4 - metabolism | Animals | Receptor, Muscarinic M4 - drug effects | Alzheimer Disease - metabolism | Central Nervous System Agents - pharmacology | Central Nervous System - drug effects | Antipsychotic Agents - pharmacology | Schizophrenia - drug therapy | Substance-Related Disorders - drug therapy | Receptor, Muscarinic M1 - metabolism | Antipsychotic drugs | Antiparkinsonian agents
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2011, Volume 746, pp. 195 - 209
The drive to produce safer and more receptor subtype selective drugs has sparked a renewed interest in allosteric modulators of G protein-coupled receptors.... 
Allosteric | Binding | Affinity | Efficacy | Potency | Orthosteric | Models, Biological | Allosteric Regulation | Allosteric Site | Protein Binding | Ligands | Receptors, Muscarinic - metabolism | Guanosine Triphosphate - metabolism | Radioligand Assay
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2018, Volume 175, Issue 21, pp. 4005 - 4008
Linked Articles This article is part of a themed section on Molecular Pharmacology of GPCRs. To view the other articles in this section visit... 
TARGET | CELLS | ENERGY | CALCIUM-SENSING RECEPTOR | MEMBRANE | DRUGS | PHARMACOLOGY & PHARMACY | BROWN ADIPOSE-TISSUE | MODULATION | AGONIST | Pharmacology | Themed Section
Journal Article
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2014, Volume 171, Issue 2, pp. 281 - 282
Linked Articles This article is part of a themed section on Orexin Receptors. To view the other articles in this section visit... 
PHARMACOLOGY & PHARMACY | Themed Section | Orexin Receptors
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2012, Volume 55, Issue 5, pp. 1898 - 1903
Journal Article
Nature, ISSN 0028-0836, 06/2011, Volume 474, Issue 7352, p. 521
  Adenosine receptors and β-adrenoceptors are G-protein-coupled receptors (GPCRs) that activate intracellular G proteins on binding the agonists adenosine or... 
Proteins | Data collection | Mutation | Binding sites
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2010, Volume 161, Issue 6, pp. 1276 - 1290
Journal Article
Journal Article
Journal Article
Current Opinion in Cell Biology, ISSN 0955-0674, 2013, Volume 27, Issue 1, pp. 94 - 101
Journal Article