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Journal Article
Bone, ISSN 8756-3282, 2016
Abstract Mechanical loading is the primary functional determinant of bone mass and architecture, and osteocytes play a key role in translating mechanical... 
Orthopedics
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 06/2017, Volume 35, Issue 4, pp. 244 - 244
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2015, Volume 30, Issue 3, pp. 423 - 435
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2009, Volume 24, Issue 4, pp. 753 - 753
Journal Article
Frontiers in endocrinology, ISSN 1664-2392, 2015, Volume 6, p. 52
Investigations into the effect of (re)modeling stimuli on cortical bone in rodents normally rely on analysis of changes in bone mass and architecture at a... 
Journal Article
FEBS Letters, ISSN 0014-5793, 08/2011, Volume 585, Issue 15, pp. 2450 - 2454
► down-regulation is stimulated by mechanical strain in osteoblastic cells. ► /Osteocalcin regulation by strain in Saos2 osteoblastic cells requires Cox2. ►... 
Osteoporosis | Sclerostin | PGE2 signaling | Mechanical strain | parathyroid hormone | extracellular signal-regulated kinase | BMP | PTH | prostaglandin | TCS | quantitative reverse transcriptase polymerase chain reaction | qRT-PCR | PKA | PKC | mitogen activated protein kinase | MAPK | bone morphogenetic protein | Cox | TCS2510 | cyclo-oxygenase | protein kinase A | protein kinase C | ERK | ACTIVATION | STIMULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EARLY RESPONSES | CELL BIOLOGY | BIOPHYSICS | BONE-FORMATION | ESTROGEN-RECEPTOR-ALPHA | IN-VIVO | SELECTIVE AGONIST | EXPRESSION | PROSTAGLANDIN E-2 | MODULATION | Dinoprostone - metabolism | Biomechanical Phenomena | Signal Transduction | Genetic Markers - genetics | Humans | Cells, Cultured | Stress, Mechanical | Osteoblasts - metabolism | Bone Morphogenetic Proteins - genetics | Down-Regulation - genetics | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Parathyroid hormone | Prostaglandins E | DNA polymerases | Bone morphogenetic proteins | Mitogens | Protein kinases | Index Medicus | PG, prostaglandin | qRT-PCR, quantitative reverse transcriptase polymerase chain reaction | PKC, protein kinase C | TCS, TCS2510 | PTH, parathyroid hormone | Cox, cyclo-oxygenase | ERK, extracellular signal-regulated kinase | BMP, bone morphogenetic protein | MAPK, mitogen activated protein kinase | PKA, protein kinase A
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 02/2013, Volume 28, Issue 2, p. 291
  Estrogen receptor-[alpha] (ER[alpha]) is crucial for the adaptive response of bone to loading but the role of endogenous estradiol (E2) for this response is... 
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0140260 - e0140260
Genome Wide Association Studies suggest that Wnt16 is an important contributor to the mechanisms controlling bone mineral density, cortical thickness, bone... 
OSTEOCYTES | MINERAL DENSITY | OSTEOGENIC RESPONSE | MULTIDISCIPLINARY SCIENCES | GROWTH | GENE-EXPRESSION | GENOME-WIDE | LOAD-BEARING | MUTATIONS | RECEPTOR-ALPHA | BETA | Estrogens - pharmacology | Ovariectomy | Mice, Inbred C57BL | Male | Tibia - drug effects | Wnt Proteins - metabolism | Gene Expression Regulation - drug effects | Animals | Wnt Proteins - genetics | Osteoporosis - metabolism | Estrogen Receptor alpha - metabolism | Female | Osteoporosis - genetics | Weight-Bearing | Mice | Tibia - metabolism | Estrogens - metabolism | Osteoporosis - physiopathology | Tibia - physiopathology | Aging - metabolism | Osteoporosis | Physiological aspects | Bones | Genetic aspects | Research | Wnt proteins | Density | Risk factors | Estrogens | Genomes | Males | Osteoblasts | Estradiol | Biomedical materials | Tibia | Mechanical loading | Rodents | Cooperation | Bone marrow | Aging | Biocompatibility | Bone loss | Bone (cortical) | Bone strength | Age | Medical research | Kidneys | Mechanical unloading | Unloading | Mechanical properties | Tamoxifen | Gene expression | Nutrition research | Sex hormones | Bone mass | Osteoclasts | Bone mineral density | Mutation | Females | Index Medicus | CORTICAL BONE | FEMALE MICE | Cell and Molecular Biology | MALE-MICE | KAPPA-B | OSTEOGENIC | RESPONSE | Cell- och molekylärbiologi
Journal Article
Journal Article