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1. cGMP
: generators, effectors and therapeutic implications
by Hofmann, Franz, Prof and Stasch, Johannes-Peter and Antos, L. K. (Laura K.) and Schmidt, Harald H. H. W
2009, Handbook of experimental pharmacology, ISBN 9783540689645, Volume 191, xiv, 583
This book is a celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field to patients and the way in which the... 
Cyclic guanylic acid | Cyclic GMP | Biochemistry | Medical Biochemistry | Molecular Medicine | Biomedicine | Human Physiology | Pharmacology/Toxicology
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2. Full Text Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels
by Stasch, Johannes-Peter and Schmidt, Peter M and Nedvetsky, Pavel I and Nedvetskaya, Tatiana Y and Arun Kumar, H.S and Meurer, Sabine and Deile, Martin and Taye, Ashraf and Knorr, Andreas and Lapp, Harald and Müller, Helmut and Turgay, Yagmur and Rothkegel, Christiane and Tersteegen, Adrian and Kemp-Harper, Barbara and Müller-Esterl, Werner and Schmidt, Harald H. H. W
Journal of Clinical Investigation, ISSN 0021-9738, 09/2006, Volume 116, Issue 9, pp. 2552 - 2561
ROS are a risk factor of several cardiovascular disorders and interfere with NO/soluble guanylyl cyclase/cyclic GMP (NO/sGC/cGMP) signaling through scavenging... 
SYSTEM | MEDICINE, RESEARCH & EXPERIMENTAL | SOLUBLE GUANYLYL CYCLASE | METHYLENE-BLUE | SPONTANEOUSLY HYPERTENSIVE-RATS | DEPENDENT PROTEIN-KINASE | NITROGLYCERIN TREATMENT | ANGIOTENSIN-II | DYSFUNCTION | SUPEROXIDE ANION PRODUCTION | EXPRESSION | Endothelium, Vascular - cytology | Reactive Oxygen Species - metabolism | Rats, Wistar | Oxidative Stress - physiology | Endothelium, Vascular - drug effects | Vasodilation | Endothelium, Vascular - physiology | Guanylate Cyclase - drug effects | Swine | Guanylate Cyclase - physiology | Heme | Blood Pressure - drug effects | Cell Culture Techniques | Rats, Inbred SHR | Oxidation-Reduction | Receptors, Cytoplasmic and Nuclear - drug effects | Rats | Receptors, Cytoplasmic and Nuclear - physiology | Soluble Guanylyl Cyclase | Benzoates - chemical synthesis | Pulmonary Artery | Animals | Cyclic GMP - metabolism | Benzoates - pharmacology | Oxidative Stress - drug effects | Blood Vessels - physiology
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3. Full Text PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock
by Thiele, Holger and Akin, Ibrahim and Sandri, Marcus and Fuernau, Georg and de Waha, Suzanne and Meyer-Saraei, Roza and Nordbeck, Peter and Geisler, Tobias and Landmesser, Ulf and Skurk, Carsten and Fach, Andreas and Lapp, Harald and Piek, Jan J and Noc, Marko and Goslar, Tomaž and Felix, Stephan B and Maier, Lars S and Stepinska, Janina and Oldroyd, Keith and Serpytis, Pranas and Montalescot, Gilles and Barthelemy, Olivier and Huber, Kurt and Windecker, Stephan and Savonitto, Stefano and Torremante, Patrizia and Vrints, Christiaan and Schneider, Steffen and Desch, Steffen and Zeymer, Uwe and CULPRIT-SHOCK Investigators
The New England Journal of Medicine, ISSN 0028-4793, 12/2017, Volume 377, Issue 25, pp. 2419 - 2432
Among patients who had multivessel coronary disease and acute myocardial infarction with cardiogenic shock, the 30-day risk of death or renal-replacement... 
ANGIOGRAPHIC FINDINGS | SURVIVAL | MULTIVESSEL DISEASE | MEDICINE, GENERAL & INTERNAL | PERCUTANEOUS CORONARY INTERVENTION | EARLY REVASCULARIZATION | ANGIOPLASTY | MANAGEMENT | RANDOMIZED-TRIAL | OPEN-LABEL | CULPRIT LESION | Myocardial Infarction - mortality | Time-to-Treatment | Humans | Middle Aged | Kaplan-Meier Estimate | Renal Replacement Therapy | Shock, Cardiogenic - mortality | Male | Risk | Renal Insufficiency - etiology | Myocardial Infarction - complications | Myocardial Infarction - therapy | Renal Insufficiency - therapy | Shock, Cardiogenic - etiology | Coronary Artery Disease - therapy | Percutaneous Coronary Intervention - methods | Coronary Artery Disease - complications | Female | Aged | Treatment outcome | Care and treatment | Usage | Coronary artery bypass | Cardiogenic shock | Cardiac patients | Analysis | Heart attack | Myocardial infarction | Shock | Cerebral infarction | Stroke | Heart attacks | Kidneys | Creatine kinase | Angioplasty | Coronary artery | Cardiovascular disease | Creatine | Bleeding | Clinical outcomes | Troponin T | Troponin | Calcium-binding protein | Coronary vessels | Renal failure | Electrocardiography | Death | Cardiology | Heart diseases | Stents | Kidney transplantation | Life Sciences | Human health and pathology
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4. Full Text Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
by Cannon, Christopher P and Blazing, Michael A and Giugliano, Robert P and McCagg, Amy and White, Jennifer A and Theroux, Pierre and Darius, Harald and Lewis, Basil S and Ophuis, Ton Oude and Jukema, J. Wouter and De Ferrari, Gaetano M and Ruzyllo, Witold and De Lucca, Paul and Im, KyungAh and Bohula, Erin A and Reist, Craig and Wiviott, Stephen D and Tershakovec, Andrew M and Musliner, Thomas A and Braunwald, Eugene and Califf, Robert M and IMPROVW-IT Investigators and IMPROVE-IT Investigators
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
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5. Full Text One-Year Outcomes after PCI Strategies in Cardiogenic Shock
by Thiele, Holger and Akin, Ibrahim and Sandri, Marcus and de Waha-Thiele, Suzanne and Meyer-Saraei, Roza and Fuernau, Georg and Eitel, Ingo and Nordbeck, Peter and Geisler, Tobias and Landmesser, Ulf and Skurk, Carsten and Fach, Andreas and Jobs, Alexander and Lapp, Harald and Piek, Jan J and Noc, Marko and Goslar, Tomaž and Felix, Stephan B and Maier, Lars S and Stepinska, Janina and Oldroyd, Keith and Serpytis, Pranas and Montalescot, Gilles and Barthelemy, Olivier and Huber, Kurt and Windecker, Stephan and Hunziker, Lukas and Savonitto, Stefano and Torremante, Patrizia and Vrints, Christiaan and Schneider, Steffen and Zeymer, Uwe and Desch, Steffen and CULPRIT-SHOCK Investigators
The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 18, pp. 1699 - 1710
In a randomized trial, 706 patients with acute myocardial infarction and cardiogenic shock were assigned to either culprit-lesion-only PCI or immediate... 
ANGIOGRAPHIC FINDINGS | MULTIVESSEL DISEASE | MEDICINE, GENERAL & INTERNAL | PERCUTANEOUS CORONARY INTERVENTION | EARLY REVASCULARIZATION | ACUTE MYOCARDIAL-INFARCTION | RANDOMIZED-TRIAL | ONE-YEAR SURVIVAL | OPEN-LABEL | ST-SEGMENT ELEVATION | CULPRIT LESION | Recurrence | Follow-Up Studies | Patient Readmission | Shock, Cardiogenic - therapy | Humans | Middle Aged | Kaplan-Meier Estimate | Renal Replacement Therapy | Shock, Cardiogenic - mortality | Male | Renal Insufficiency - etiology | Myocardial Infarction - complications | Renal Insufficiency - therapy | Shock, Cardiogenic - etiology | Percutaneous Coronary Intervention - methods | Female | Aged | Heart Failure - epidemiology | Heart Failure - etiology | Heart | Treatment outcome | Care and treatment | Usage | Cardiogenic shock | Analysis | Surgery | Heart failure | Myocardial infarction | Short term | Fees & charges | Shock | Heart attacks | Kidneys | Mortality | Coronary artery | Cardiovascular disease | Congestive heart failure | Patients | Information sharing | Coronary vessels | Renal failure | Death | Stents | Life Sciences | Human health and pathology
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