X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (12) 12
index medicus (12) 12
animals (11) 11
mice (10) 10
research (8) 8
diabetes (7) 7
gene expression (7) 7
biochemistry & molecular biology (6) 6
genetic aspects (6) 6
microrna (6) 6
proteins (6) 6
mice, knockout (5) 5
micrornas - genetics (5) 5
phosphorylation (5) 5
signal transduction (5) 5
care and treatment (4) 4
female (4) 4
genes (4) 4
genetics (4) 4
history (4) 4
insulin (4) 4
insulin - metabolism (4) 4
insulin-secreting cells - metabolism (4) 4
male (4) 4
medicine, research & experimental (4) 4
micrornas - metabolism (4) 4
oncogene proteins - metabolism (4) 4
oncogene proteins - physiology (4) 4
pancreatic beta cells (4) 4
rodents (4) 4
abridged index medicus (3) 3
adaptor proteins, signal transducing (3) 3
adaptor proteins, signal transducing - physiology (3) 3
aged (3) 3
cell biology (3) 3
cos cells (3) 3
endocrinology & metabolism (3) 3
homeostasis (3) 3
immunology (3) 3
insulin resistance (3) 3
middle aged (3) 3
obesity (3) 3
oncogene proteins - genetics (3) 3
pancreatic β-cells (3) 3
physiological aspects (3) 3
physiology (3) 3
research article (3) 3
type 2 diabetes (3) 3
adaptor proteins (2) 2
adaptor proteins, signal transducing - genetics (2) 2
analysis of variance (2) 2
apoptosis - genetics (2) 2
article subject (2) 2
binding sites (2) 2
biological markers (2) 2
biomarker (2) 2
breast-cancer (2) 2
cancer (2) 2
cancer patients (2) 2
cell line (2) 2
cell survival - genetics (2) 2
cell-survival (2) 2
cellular biology (2) 2
cercopithecus aethiops (2) 2
development and progression (2) 2
diabetes mellitus, type 2 - genetics (2) 2
diabetes mellitus, type 2 - pathology (2) 2
domain (2) 2
eif-2 kinase - metabolism (2) 2
endocrine system diseases (2) 2
endoplasmic reticulum (2) 2
eukaryotic initiation factor-2 - metabolism (2) 2
experiments (2) 2
expression (2) 2
gene expression regulation (2) 2
gene-expression (2) 2
glucose (2) 2
hela cells (2) 2
hsp40 heat-shock proteins - biosynthesis (2) 2
hypogonadism (2) 2
infertility (2) 2
inhibition (2) 2
insulin-secreting cells - pathology (2) 2
kinase (2) 2
macromolecular substances (2) 2
mice, inbred c57bl (2) 2
mice, inbred nod (2) 2
mice, obese (2) 2
mice, transgenic (2) 2
micrornas (2) 2
mirna-375 (2) 2
molecular biology (2) 2
molecular medicine (2) 2
multidisciplinary sciences (2) 2
mutation (2) 2
nck (2) 2
other (2) 2
pancreas (2) 2
protein (2) 2
protein binding (2) 2
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 15, pp. 1493 - 1505
Journal Article
Diabetes, ISSN 0012-1797, 05/2018, Volume 67, Issue Supplement 1, p. 52
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2015, Volume 21, Issue 6, pp. 619 - 627
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2017, Volume 127, Issue 3, pp. 1061 - 1074
Journal Article
International journal of endocrinology, ISSN 1687-8337, 2018, Volume 2018, pp. 9514927 - 2
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 03/2011, Volume 300, Issue 3, pp. 423 - 434
Obesity has been shown to create stress in the endoplasmic reticulum (ER), and that initiates the activation of the unfolded protein response (UPR). This has... 
Adaptor proteins | Insulin receptor substrate-1 | Insulin resistance | Noncatalytic region of tyrosine kinase | terminal kinase pathway | Diabetes | Inositol-requiring enzyme-1-c-Jun NH | Endoplasmic reticulum | insulin receptor substrate-1 | LOCALIZATION | PHYSIOLOGY | UNFOLDED-PROTEIN RESPONSE | ENDOPLASMIC-RETICULUM STRESS | adaptor proteins | CELL-SURVIVAL | noncatalytic region of tyrosine kinase | MESSENGER-RNA | IRE1 | ENDOCRINOLOGY & METABOLISM | RESISTANCE | inositol-requiring enzyme-1-c-Jun NH2-terminal kinase pathway | BAX INHIBITOR-1 | insulin resistance | diabetes | ADAPTER PROTEIN | ATF6 | endoplasmic reticulum | Oncogene Proteins - genetics | Phosphorylation | Insulin - physiology | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Oncogene Proteins - physiology | Insulin Resistance - physiology | Glycogen - biosynthesis | HEK293 Cells | Membrane Proteins - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Glucose Intolerance - physiopathology | Protein-Serine-Threonine Kinases - metabolism | Glucose Intolerance - genetics | Unfolded Protein Response - genetics | Membrane Proteins - genetics | Endoplasmic Reticulum - physiology | Protein-Serine-Threonine Kinases - genetics | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Adaptor Proteins, Signal Transducing - physiology | Animals | Homeostasis - physiology | Adaptor Proteins, Signal Transducing - genetics | Insulin Resistance - genetics | Liver - physiology | Mice, Obese | Signal Transduction - physiology | Mice | Blood Glucose - metabolism | Unfolded Protein Response - physiology | Gene mutations | Physiological aspects | Genetic aspects | Stress (Physiology) | Research
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, pp. 26633 - 26644
Stress imposed on the endoplasmic reticulum (ER) induces the phosphorylation of the alpha-subunit of the eukaryotic initiation factor 2 (eIF2) on Ser(51). This... 
SH2/SH3 ADAPTER PROTEIN | INDUCED GENE-EXPRESSION | MESSENGER-RNA TRANSLATION | UNFOLDED PROTEIN RESPONSE | INHIBITION | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | GAMMA34.5 PROTEIN | MAMMALIAN-CELLS | TRANSCRIPTION FACTOR
Journal Article
Frontiers in Genetics, ISSN 1664-8021, 01/2017, Volume 7, p. 226
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2017, Volume 127, Issue 3, p. 1061
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2014, Volume 124, Issue 6, p. 2722
Dysfunctional microRNA (miRNA) networks contribute to inappropriate responses following pathological stress and are the underlying cause of several disease... 
Type 2 diabetes | Pancreatic beta cells | MicroRNA | Development and progression | Genetic aspects | Properties | Genetic regulation | Transcription factors | Adrenal glands | Genomes | Grants | Gene expression | Insulin | Experiments | Studies | Hyperglycemia | Animals | Rodents | Insulin resistance | Diabetes | Pancreas
Journal Article