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Gastroenterology, ISSN 0016-5085, 08/2019
It has been a challenge to develop fully functioning cells from human pluripotent stem cells (hPSCs). We investigated how activation of hedgehog signaling... 
Journal Article
Gastroenterology, ISSN 0016-5085, 12/2018, Volume 155, Issue 6, pp. 1908 - 1922.e5
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2011, Volume 121, Issue 9, pp. 3467 - 3478
Hirschsprung (HSCR) disease is a complex genetic disorder attributed to a failure of the enteric neural crest cells (ENCCs) to form ganglia in the hindgut.... 
MEDICINE, RESEARCH & EXPERIMENTAL | NERVOUS-SYSTEM | PROGENITORS | STEM-CELLS | INHIBITION | NOTCH ACTIVATION | NEUROGENESIS | PROLIFERATION | DIFFERENTIATION | NEURAL CREST CELLS | GENOME-WIDE ASSOCIATION | Enteric Nervous System - cytology | Receptors, Notch - metabolism | Humans | Hirschsprung Disease - genetics | Hedgehog Proteins - metabolism | Receptors, Notch - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Neuroglia - cytology | Hedgehog Proteins - genetics | Gastrointestinal Tract - physiology | Gene Expression Regulation, Developmental | Membrane Proteins - metabolism | Patched Receptors | Cell Differentiation - physiology | Intracellular Signaling Peptides and Proteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Neural Crest - cytology | Membrane Proteins - genetics | Hirschsprung Disease - physiopathology | Cells, Cultured | Neuroglia - physiology | Receptors, Cell Surface - metabolism | Neural Crest - physiology | Animals | Epistasis, Genetic | Neurogenesis - physiology | Signal Transduction - physiology | Gastrointestinal Tract - cytology | Mice | Polymorphism, Single Nucleotide | Enteric Nervous System - physiology | Patched-1 Receptor | Receptors, Cell Surface - genetics | Hirschsprung's disease | Cell proliferation | Care and treatment | Intestine, Small | Growth | Physiological aspects | Genetic aspects | Cellular signal transduction | Diagnosis | Gene expression | Nervous system, Autonomic
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 08/2015, Volume 1852, Issue 8, pp. 1676 - 1686
A germline mutation (A339V) in thyroid transcription factor-1 ( / ) was shown to be associated with multinodular goiter (MNG) and papillary thyroid carcinoma... 
Proliferation | TTF1 | Multinodular goiter | Proteomics | MIGRATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | STAT3 | MARKERS | RECEPTOR | CANCER | THYROTROPIN | INVASION | BIOPHYSICS | CARCINOMA | Clathrin | Thyroid gland | Growth | Goiter | Mass spectrometry | Analysis
Journal Article
Current cancer drug targets, 05/2011, Volume 11, Issue 4, p. 412
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 11/2011, Volume 94, Issue 11, pp. 2099 - 2105
Bruceine K (1), a pentacyclic C20‐quassinoid bearing a unique 12,20‐epoxy moiety, and bruceine L (2), along with the ten known compounds... 
Brucea javanica | Bruceines K and L | SEEDS | QUASSINOIDS | MOSAIC-VIRUS | MERR | CHEMISTRY, MULTIDISCIPLINARY | CONSTITUENTS
Journal Article
01/2009, ISBN 9781267056993
Pancreatic cancer is the forth and sixth leading cause of cancer deaths in the United States and Hong Kong, respectively. The morbidity of pancreatic cancer is... 
Alternative Medicine | Molecular biology
Dissertation
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