The New England Journal of Medicine, ISSN 0028-4793, 10/2015, Volume 373, Issue 15, pp. 1397 - 1407
This multicenter, randomized, controlled trial involving adults undergoing elective cardiac surgery with cardiopulmonary bypass while under propofol anesthesia...
ACUTE KIDNEY INJURY | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | THERAPY | MYOCARDIAL-INFARCTION | CARDIAC-SURGERY | DOUBLE-BLIND | COMPLICATIONS | RANDOMIZED CONTROLLED-TRIAL | BYPASS GRAFT-SURGERY | CARDIOPROTECTION | Length of Stay | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Kaplan-Meier Estimate | Postoperative Complications - prevention & control | Male | Anesthesia, Intravenous | Cardiopulmonary Bypass | Upper Extremity - blood supply | Ischemic Preconditioning - methods | Cardiac Surgical Procedures | Ischemia | Treatment Failure | Troponin - blood | Female | Aged | Propofol | Elective Surgical Procedures | Cardiopulmonary bypass | Heart | Treatment outcome | Vasomotor conditioning | Usage | Analysis | Surgery | Clinical trials | Health aspects | Myocardial infarction | Cerebral infarction | Intravenous administration | Heart surgery | Patients | Clinical outcomes | Troponin | Reperfusion | Fibrillation | Calcium-binding protein | Renal failure | Ventilation | Anesthesia | Cardiology
ACUTE KIDNEY INJURY | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | THERAPY | MYOCARDIAL-INFARCTION | CARDIAC-SURGERY | DOUBLE-BLIND | COMPLICATIONS | RANDOMIZED CONTROLLED-TRIAL | BYPASS GRAFT-SURGERY | CARDIOPROTECTION | Length of Stay | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Kaplan-Meier Estimate | Postoperative Complications - prevention & control | Male | Anesthesia, Intravenous | Cardiopulmonary Bypass | Upper Extremity - blood supply | Ischemic Preconditioning - methods | Cardiac Surgical Procedures | Ischemia | Treatment Failure | Troponin - blood | Female | Aged | Propofol | Elective Surgical Procedures | Cardiopulmonary bypass | Heart | Treatment outcome | Vasomotor conditioning | Usage | Analysis | Surgery | Clinical trials | Health aspects | Myocardial infarction | Cerebral infarction | Intravenous administration | Heart surgery | Patients | Clinical outcomes | Troponin | Reperfusion | Fibrillation | Calcium-binding protein | Renal failure | Ventilation | Anesthesia | Cardiology
Journal Article
European Journal of Anaesthesiology, ISSN 0265-0215, 12/2013, Volume 30, Issue 12, pp. 758 - 763
BACKGROUNDPreoperative anxiety and need for information can be detected during preoperative consultation via structured and standardised screening by the...
Prospective Studies | Age Factors | Physicians | Humans | Middle Aged | Self Report | Male | Health Services Needs and Demand | Elective Surgical Procedures - psychology | Adult | Anxiety - diagnosis | Female | Surveys and Questionnaires | Aged | Anxiety - etiology | Germany | Preoperative Care - methods
Prospective Studies | Age Factors | Physicians | Humans | Middle Aged | Self Report | Male | Health Services Needs and Demand | Elective Surgical Procedures - psychology | Adult | Anxiety - diagnosis | Female | Surveys and Questionnaires | Aged | Anxiety - etiology | Germany | Preoperative Care - methods
Journal Article
European Journal of Anaesthesiology, ISSN 0265-0215, 12/2013, Volume 30, Issue 12, pp. 758 - 763
BACKGROUNDPreoperative anxiety and need for information can be detected during preoperative consultation via structured and standardised screening by the...
VALIDATION | ANESTHESIA | DISORDERS | ANESTHESIOLOGY | OUTCOMES | INFORMATION SCALE APAIS
VALIDATION | ANESTHESIA | DISORDERS | ANESTHESIOLOGY | OUTCOMES | INFORMATION SCALE APAIS
Journal Article
Lancet, The, ISSN 0140-6736, 2014, Volume 384, Issue 9942, pp. 495 - 503
Summary Background The role of positive end-expiratory pressure in mechanical ventilation during general anaesthesia for surgery remains uncertain. Levels of...
Internal Medicine | POSTOPERATIVE PULMONARY COMPLICATIONS | MECHANICALLY VENTILATED PATIENTS | MEDICINE, GENERAL & INTERNAL | MULTIFACTORIAL RISK INDEX | VOLUME | PREVENTS | ATELECTASIS | RESPIRATORY-DISTRESS-SYNDROME | STRATEGIES | South America | Postoperative Complications - etiology | Double-Blind Method | Anesthesia, General - methods | Europe | Humans | Lung Diseases - prevention & control | Middle Aged | Risk Factors | Postoperative Complications - prevention & control | Positive-Pressure Respiration - adverse effects | Male | Treatment Outcome | Anesthesia, General - adverse effects | Positive-Pressure Respiration - methods | Tidal Volume | North America | Abdomen - surgery | Lung Diseases - etiology | Female | Aged | Surgical Procedures, Operative - methods | Surgical Procedures, Operative - adverse effects | Complications and side effects | Anesthesia | Drug therapy | Health aspects | Lung diseases | Abdominal surgery | Respiratory distress syndrome | Mortality | Medical and Health Sciences | Medicin och hälsovetenskap
Internal Medicine | POSTOPERATIVE PULMONARY COMPLICATIONS | MECHANICALLY VENTILATED PATIENTS | MEDICINE, GENERAL & INTERNAL | MULTIFACTORIAL RISK INDEX | VOLUME | PREVENTS | ATELECTASIS | RESPIRATORY-DISTRESS-SYNDROME | STRATEGIES | South America | Postoperative Complications - etiology | Double-Blind Method | Anesthesia, General - methods | Europe | Humans | Lung Diseases - prevention & control | Middle Aged | Risk Factors | Postoperative Complications - prevention & control | Positive-Pressure Respiration - adverse effects | Male | Treatment Outcome | Anesthesia, General - adverse effects | Positive-Pressure Respiration - methods | Tidal Volume | North America | Abdomen - surgery | Lung Diseases - etiology | Female | Aged | Surgical Procedures, Operative - methods | Surgical Procedures, Operative - adverse effects | Complications and side effects | Anesthesia | Drug therapy | Health aspects | Lung diseases | Abdominal surgery | Respiratory distress syndrome | Mortality | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
BMC Psychiatry, ISSN 1471-244X, 03/2018, Volume 18, Issue 1, pp. 82 - 8
Background: Ongoing pain after surgery is a major problem and influences recovery and the quality of life of the patient. Associations between anxiety and...
Postoperative pain | Analgesics | Opioids | Prediction | Spine surgery | Anxiety | Lumbar | PSYCHIATRY | HERNIATION | RESEARCH-TRIAL SPORT | BACK-PAIN | OBESITY | GAD-7 | DISORDER | GENDER | PREOPERATIVE ANXIETY | OUTCOMES | Disability Evaluation | Analgesics - therapeutic use | Predictive Value of Tests | Chronic Pain - drug therapy | Prospective Studies | Pain, Postoperative - drug therapy | Pain, Postoperative - psychology | Humans | Middle Aged | Anxiety - psychology | Male | Chronic Pain - psychology | Intervertebral Disc Displacement - psychology | Lumbar Vertebrae - surgery | Pain Measurement - methods | Quality of Life | Adult | Female | Intervertebral Disc Displacement - surgery | Longitudinal Studies | Anxiety - etiology | Preoperative Period
Postoperative pain | Analgesics | Opioids | Prediction | Spine surgery | Anxiety | Lumbar | PSYCHIATRY | HERNIATION | RESEARCH-TRIAL SPORT | BACK-PAIN | OBESITY | GAD-7 | DISORDER | GENDER | PREOPERATIVE ANXIETY | OUTCOMES | Disability Evaluation | Analgesics - therapeutic use | Predictive Value of Tests | Chronic Pain - drug therapy | Prospective Studies | Pain, Postoperative - drug therapy | Pain, Postoperative - psychology | Humans | Middle Aged | Anxiety - psychology | Male | Chronic Pain - psychology | Intervertebral Disc Displacement - psychology | Lumbar Vertebrae - surgery | Pain Measurement - methods | Quality of Life | Adult | Female | Intervertebral Disc Displacement - surgery | Longitudinal Studies | Anxiety - etiology | Preoperative Period
Journal Article
BMC Anesthesiology, ISSN 1471-2253, 10/2016, Volume 16, Issue 1, p. 91
Background: Pain after surgery is a major issue for patient discomfort and often associated with delayed recovery. The aim of the present study was to evaluate...
Postoperative pain | Analgesics | Outcome | Chronic pain | PERSISTENT POSTSURGICAL PAIN | POPULATION | RISK-FACTORS | PREDICTORS | DISABILITY | ANESTHESIOLOGY | QUALITY-OF-LIFE | PREOPERATIVE OPIOID USE | Prevalence | Prospective Studies | Pain, Postoperative - drug therapy | Humans | Middle Aged | Elective Surgical Procedures - adverse effects | Male | Young Adult | Chronic Pain - epidemiology | Time Factors | Aged, 80 and over | Adult | Female | Surveys and Questionnaires | Elective Surgical Procedures - methods | Chronic Pain - etiology | Chronic Pain - drug therapy | Analgesics - administration & dosage | Analgesics, Opioid - administration & dosage | Pain, Postoperative - epidemiology | Adolescent | Aged | Pain Measurement | Cohort Studies | Preoperative Period | Complications and side effects | Care and treatment | Pain | Dosage and administration | Research | Drug therapy | Risk factors | Methods
Postoperative pain | Analgesics | Outcome | Chronic pain | PERSISTENT POSTSURGICAL PAIN | POPULATION | RISK-FACTORS | PREDICTORS | DISABILITY | ANESTHESIOLOGY | QUALITY-OF-LIFE | PREOPERATIVE OPIOID USE | Prevalence | Prospective Studies | Pain, Postoperative - drug therapy | Humans | Middle Aged | Elective Surgical Procedures - adverse effects | Male | Young Adult | Chronic Pain - epidemiology | Time Factors | Aged, 80 and over | Adult | Female | Surveys and Questionnaires | Elective Surgical Procedures - methods | Chronic Pain - etiology | Chronic Pain - drug therapy | Analgesics - administration & dosage | Analgesics, Opioid - administration & dosage | Pain, Postoperative - epidemiology | Adolescent | Aged | Pain Measurement | Cohort Studies | Preoperative Period | Complications and side effects | Care and treatment | Pain | Dosage and administration | Research | Drug therapy | Risk factors | Methods
Journal Article
European Journal of Anaesthesiology, ISSN 0265-0215, 05/2019, Volume 36, Issue 5, pp. 369 - 374
BACKGROUNDPostoperative nausea and vomiting (PONV) is an extremely distressing side effect for patients. Despite PONV prophylaxis guided by well established...
DIMENSIONS | ANESTHESIA | RISK-FACTORS | SCORE | INDEX-3 | ANESTHESIOLOGY | PREOPERATIVE ANXIETY | RELIABILITY | SCALE | VALIDITY | Vomiting | Complications | Surgery | Anxiety | Nausea | Diagnosis | Risk factors
DIMENSIONS | ANESTHESIA | RISK-FACTORS | SCORE | INDEX-3 | ANESTHESIOLOGY | PREOPERATIVE ANXIETY | RELIABILITY | SCALE | VALIDITY | Vomiting | Complications | Surgery | Anxiety | Nausea | Diagnosis | Risk factors
Journal Article
Deutsches Arzteblatt International, ISSN 1866-0452, 03/2018, Volume 115, Issue 9, pp. 135 - 142
Background: Rotating several different WHO level III opioid drugs is a therapeutic option for patients with chronic cancer-related pain who suffer from...
OXYCODONE | TAPENTADOL PROLONGED RELEASE | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | EFFICACY | METHADONE | CONVERSION | MORPHINE | SAFETY | TITRATION | EXTENDED-RELEASE | Original
OXYCODONE | TAPENTADOL PROLONGED RELEASE | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | EFFICACY | METHADONE | CONVERSION | MORPHINE | SAFETY | TITRATION | EXTENDED-RELEASE | Original
Journal Article
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie, ISSN 0939-2661, 2011, Volume 46, Issue 5, pp. 354 - 363
Journal Article
Deutsches Arzteblatt international, ISSN 1866-0452, 03/2018, Volume 115, Issue 9, p. 135
Rotating several different WHO level III opioid drugs is a therapeutic option for patients with chronic cancer-related pain who suffer from inadequate...
Journal Article
European journal of anaesthesiology, ISSN 0265-0215, 2017, Volume 34, Issue 4, pp. 229 - 238
BACKGROUND Postoperative pulmonary complications (PPCs) are common after major abdominal surgery. The kinetics of plasma biomarkers could improve...
LOWER TIDAL VOLUMES | CARDIAC-SURGERY | MECHANICAL VENTILATION | RECEPTOR | ANESTHESIOLOGY | RANDOMIZED CONTROLLED-TRIAL | GENERAL-ANESTHESIA | OPEN ABDOMINAL-SURGERY | RESPIRATORY-DISTRESS-SYNDROME | GLYCATION END-PRODUCTS | CLINICAL-OUTCOMES | Lung Injury - blood | Humans | Inflammation Mediators - blood | Postoperative Complications - blood | Positive-Pressure Respiration - adverse effects | Male | Positive-Pressure Respiration - trends | Postoperative Complications - epidemiology | Biomarkers - blood | Inflammation - epidemiology | Lung Injury - diagnosis | Lung Injury - epidemiology | Inflammation - blood | Postoperative Complications - diagnosis | Adult | Female | Inflammation - diagnosis
LOWER TIDAL VOLUMES | CARDIAC-SURGERY | MECHANICAL VENTILATION | RECEPTOR | ANESTHESIOLOGY | RANDOMIZED CONTROLLED-TRIAL | GENERAL-ANESTHESIA | OPEN ABDOMINAL-SURGERY | RESPIRATORY-DISTRESS-SYNDROME | GLYCATION END-PRODUCTS | CLINICAL-OUTCOMES | Lung Injury - blood | Humans | Inflammation Mediators - blood | Postoperative Complications - blood | Positive-Pressure Respiration - adverse effects | Male | Positive-Pressure Respiration - trends | Postoperative Complications - epidemiology | Biomarkers - blood | Inflammation - epidemiology | Lung Injury - diagnosis | Lung Injury - epidemiology | Inflammation - blood | Postoperative Complications - diagnosis | Adult | Female | Inflammation - diagnosis
Journal Article
BMJ Open, ISSN 2044-6055, 10/2018, Volume 8, Issue 10, p. e023609
IntroductionHip fracture surgery is associated with high in-hospital and 30-day mortality rates and serious adverse patient outcomes. Evidence from randomised...
anaesthesia in orthopaedics | geriatric medicine | anaesthetics | MORTALITY | SURGERY | AUDIT | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | MODE | POSTOPERATIVE DELIRIUM | VALIDATION | RELIABILITY | SCALE | LENGTH-OF-STAY | Delirium | Pneumonia | Heart attacks | Mortality | Clinical trials | Cardiovascular disease | Medical screening | Meta-analysis | Studies | Hypotheses | Hospitals | Fractures | Pain | Surgery | Older people | Questionnaires | Anesthesia | Patient satisfaction | Health risk assessment
anaesthesia in orthopaedics | geriatric medicine | anaesthetics | MORTALITY | SURGERY | AUDIT | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | MODE | POSTOPERATIVE DELIRIUM | VALIDATION | RELIABILITY | SCALE | LENGTH-OF-STAY | Delirium | Pneumonia | Heart attacks | Mortality | Clinical trials | Cardiovascular disease | Medical screening | Meta-analysis | Studies | Hypotheses | Hospitals | Fractures | Pain | Surgery | Older people | Questionnaires | Anesthesia | Patient satisfaction | Health risk assessment
Journal Article
Trials, ISSN 1745-6215, 02/2019, Volume 20, Issue 1, pp. 101 - 10
BackgroundPerioperative anaemia leads to impaired oxygen supply with a risk of vital organ ischaemia. In healthy and fit individuals, anaemia can be...
Red blood cell transfusion | elderly patients | anaemia | surgery | BLOOD-CELL TRANSFUSION | MEDICINE, RESEARCH & EXPERIMENTAL | EQ-5D | MULTICENTER | MANAGEMENT | OLDER-ADULTS | GUIDELINES | THRESHOLDS | RESTRICTIVE TRANSFUSION | Care and treatment | Mortality | Surgery | Aged patients | Forecasts and trends | Blood transfusion | Methods
Red blood cell transfusion | elderly patients | anaemia | surgery | BLOOD-CELL TRANSFUSION | MEDICINE, RESEARCH & EXPERIMENTAL | EQ-5D | MULTICENTER | MANAGEMENT | OLDER-ADULTS | GUIDELINES | THRESHOLDS | RESTRICTIVE TRANSFUSION | Care and treatment | Mortality | Surgery | Aged patients | Forecasts and trends | Blood transfusion | Methods
Journal Article
BMC cardiovascular disorders, ISSN 1471-2261, 01/2019, Volume 19, Issue 1, pp. 26 - 12
BackgroundThe aim of our study was the identification of genetic variants associated with postoperative complications after cardiac surgery.MethodsWe conducted...
Delirium | Myocardial infarction | Stroke | Genome-wide association study | Acute kidney injury | Atrial fibrillation | Cardiac surgery | DEFINITION | PHLPP2 | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | KINASE | MECHANISMS | CA2 | DYSFUNCTION | INFLAMMATORY RESPONSE | CEREBRAL ISCHEMIA/REPERFUSION INJURY | Heart | Medical research | Genome-wide association studies | Usage | Complications | Surgery | Medicine, Experimental | Genetic aspects | Research | Heart attack | Risk factors | Oxidative stress | Cardiac arrhythmia | Heart attacks | Heart surgery | Clinical trials | Ryanodine receptors | Cardiovascular disease | Genomes | Single-nucleotide polymorphism | Fibrillation | Ischemia | Rodents | Chromosomes | Cerebral infarction | Kidneys | Mortality | Studies | Genetic variance | Coronary vessels | Quality control | Renal failure
Delirium | Myocardial infarction | Stroke | Genome-wide association study | Acute kidney injury | Atrial fibrillation | Cardiac surgery | DEFINITION | PHLPP2 | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | KINASE | MECHANISMS | CA2 | DYSFUNCTION | INFLAMMATORY RESPONSE | CEREBRAL ISCHEMIA/REPERFUSION INJURY | Heart | Medical research | Genome-wide association studies | Usage | Complications | Surgery | Medicine, Experimental | Genetic aspects | Research | Heart attack | Risk factors | Oxidative stress | Cardiac arrhythmia | Heart attacks | Heart surgery | Clinical trials | Ryanodine receptors | Cardiovascular disease | Genomes | Single-nucleotide polymorphism | Fibrillation | Ischemia | Rodents | Chromosomes | Cerebral infarction | Kidneys | Mortality | Studies | Genetic variance | Coronary vessels | Quality control | Renal failure
Journal Article