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Journal Article
Nature Immunology, ISSN 1529-2908, 07/2009, Volume 10, Issue 7, pp. 713 - 720
T helper type 2 (T(H)2)-mediated immune responses are induced after infection with multicellular parasites and can be triggered by a variety of allergens. The... 
B-CELLS | IMMUNITY | ACTIVATION | DENDRITIC CELLS | MAST-CELLS | IN-VIVO | HUMAN IGE SYNTHESIS | CLASS-II TRANSACTIVATOR | IMMUNOLOGY | EXPRESSION | NALP3 INFLAMMASOME | Antigen-Presenting Cells - cytology | Male | Th2 Cells - immunology | Adoptive Transfer | CD4-Positive T-Lymphocytes - immunology | Flow Cytometry | Allergens - immunology | Bone Marrow Cells - immunology | Basophils - immunology | Trans-Activators - genetics | Female | Papain - immunology | Interleukin-4 - genetics | Nuclear Proteins - genetics | Trans-Activators - immunology | Endocytosis - immunology | Antigen-Presenting Cells - metabolism | Gene Expression | Bone Marrow Cells - cytology | CD4-Positive T-Lymphocytes - cytology | Interleukin-4 - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Nuclear Proteins - metabolism | Th2 Cells - cytology | Nuclear Proteins - immunology | Reverse Transcriptase Polymerase Chain Reaction | Antigen-Presenting Cells - immunology | Mice, Knockout | Basophils - transplantation | Cell Differentiation - immunology | Antigens, Helminth - immunology | Animals | Histocompatibility Antigens Class II - immunology | Trans-Activators - metabolism | Mice | Mice, Inbred BALB C | Histocompatibility Antigens Class II - genetics | Basophils - metabolism | Bone Marrow Cells - metabolism | Allergens | Immune response | Basophils | Physiological aspects | Genetic aspects | Research | T cells | Health aspects
Journal Article
PLoS Biology, ISSN 1544-9173, 09/2008, Volume 6, Issue 9
  The process of rescuing cells that can interact with self-peptide/MHC complexes enriches for autoreactive T cells. [...]tolerance mechanisms must be in place... 
Proteins | Immunology | Peptides | T cell receptors | Immune system
Journal Article
Nature Immunology, ISSN 1529-2908, 2009, Volume 10, Issue 7, pp. 697 - 705
  Dendritic cells can prime naive CD4+ T cells; however, here we demonstrate that dendritic cell-mediated priming was insufficient for the development of T... 
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 05/2012, Volume 109, Issue 19, pp. 7415 - 7420
Mature peripheral T cells respond to foreign but not to self-antigens. During development in the thymus, deletion of high-affinity self-reactive immature... 
Phosphorylation | Autoantigens | Medulla | Lymphocytes T | Immunological tolerance | CD4 antigen | Thymus | T-cell receptor | Signal transduction | Major histocompatibility complex | Transmission electron microscopy | Thymocytes | Topography | Lck protein | Islands | Protein-tyrosine kinase
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2012, Volume 109, Issue 19, p. 7415
Mature peripheral T cells respond to foreign but not to self-antigens. During development in the thymus, deletion of high-affinity self-reactive immature... 
Proteins | Phosphorylation | Transmission electron microscopy | Peptides | Rodents | T cell receptors
Journal Article
Science (Washington), ISSN 0036-8075, 01/2012, Volume 335, Issue 6066, pp. 342 - 344
Lifelong antibody responses to vaccination require reorganization of lymphoid tissue and dynamic intercellular communication called the germinal center... 
Antibodies
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2004, Volume 199, Issue 5, pp. 725 - 730
Control of the intracellular protozoan, Leishmania major, requires major histocompatibility complex class II (MHC II)-dependent antigen presentation and CD4(+)... 
Langerhans cells | Antigen presentation | CD4 | Macrophages | Th1 | GAMMA | MEDICINE, RESEARCH & EXPERIMENTAL | CD40 | antigen presentation | DEFICIENT MICE | IMMUNOLOGY | SUSCEPTIBLE MICE | CUTANEOUS LEISHMANIASIS | macrophages | MEDIATED-IMMUNITY | INFECTION | T-CELLS | ANTIGEN | Brief Definitive Report
Journal Article
Immunity, ISSN 1074-7613, 01/2017, Volume 46, Issue 1, pp. 51 - 64
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2011, Volume 187, Issue 3, pp. 1091 - 1095
Follicular helper T (TFH) cells are critical for germinal center (GC) formation. The processes that drive their generation and effector potential remain... 
Journal Article