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Journal Article
Developmental Cell, ISSN 1534-5807, 11/2016, Volume 39, Issue 4, pp. 452 - 465
Merlin encoded by the gene is a bona fide tumor suppressor that has been implicated in regulation of both the Hippo-Yap and Rac1-Pak1 pathways. Using... 
senescence | inflammation | DNA damage response | ROS | Yap | NF2 | Rac1 | MERLIN | ACTIVATION | SECRETORY PHENOTYPE | SIGNALING PATHWAY | LIVER | GROWTH | GENE-EXPRESSION | YAP | PROLIFERATION | DEVELOPMENTAL BIOLOGY | RAC1 | CELL BIOLOGY | Hepatomegaly - pathology | Cell Cycle - genetics | Inflammation - pathology | Liver - pathology | Cell Proliferation | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Humans | Cell Dedifferentiation | Hepatocytes - pathology | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Hepatocytes - metabolism | Carcinogenesis - metabolism | Cellular Senescence | Gene Deletion | Proto-Oncogene Proteins c-akt - metabolism | Neurofibromin 2 - metabolism | Biomarkers - metabolism | Meningioma - metabolism | Signal Transduction | Liver - metabolism | Tumor Suppressor Protein p53 - metabolism | Organ Size | Epithelial Cells - pathology | Neurilemmoma - pathology | Mice, Knockout | Carcinogenesis - pathology | Meningioma - pathology | Phenotype | Animals | Neurilemmoma - metabolism | Hepatomegaly - metabolism | Mice | DNA Damage | rac1 GTP-Binding Protein - metabolism | Medical colleges | DNA damage | Analysis | Liver | DNA | Genetically modified organisms | Development and progression | Genetic engineering | Inflammation | Tumor proteins | Tumors | DNA repair | Senescence
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