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1. Full Text Cellular diversity in the colon: another brick in the wall
by Cleynen, Isabelle and Laukens, Debby
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 07/2019, Volume 16, Issue 7, pp. 391 - 392
Single-cell RNA profiling of colonic epithelial crypts from healthy volunteers and patients with ulcerative colitis adds pH- regulating colonocytes and goblet... 
GASTROENTEROLOGY & HEPATOLOGY | BARRIER | Ulcerative colitis | Goblet cells | Colon | Ribonucleic acid--RNA | Epithelial cells | Index Medicus
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2. Full Text Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
by Jostins, Luke and Ripke, Stephan and Weersma, Rinse K and Duerr, Richard H and McGovern, Dermot P and Hui, Ken Y and Lee, James C and Schumm, L. Philip and Sharma, Yashoda and Anderson, Carl A and Essers, Jonah and Mitrovic, Mitja and Ning, Kaida and Cleynen, Isabelle and Theatre, Emilie and Spain, Sarah L and Raychaudhuri, Soumya and Goyette, Philippe and Wei, Zhi and Abraham, Clara and Achkar, Jean-Paul and Ahmad, Tariq and Amininejad, Leila and Ananthakrishnan, Ashwin N and Andersen, Vibeke and Anews, Jane M and Baidoo, Leonard and Balschun, Tobias and Bampton, Peter A and Bitton, Alain and Boucher, Gabrielle and Brand, Stephan and Büning, Carsten and Cohain, Ariella and Cichon, Sven and D'Amato, Mauro and de Jong, Dirk and Devaney, Kathy L and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Ferguson, Lynnette R and Franchimont, Denis and Fransen, Karin and Gearry, Richard and Georges, Michel and Gieger, Christian and Glas, Jürgen and Haritunians, Talin and Hart, Ailsa and Hawkey, Chris and Hedl, Matija and Hu, Xinli and Karlsen, Tom H and Kupcinskas, Limas and Kugathasan, Subra and Latiano, Anna and Laukens, Debby and Lawrance, Ian C and Lees, Charlie W and Louis, Edouard and Mahy, Gillian and Mansfield, John and Morgan, Angharad R and Mowat, Craig and Newman, William and Palmieri, Orazio and Ponsioen, Cyriel Y and Potocnik, Uros and Prescott, Natalie J and Regueiro, Miguel and Rotter, Jerome I and Russell, Richard K and Sanderson, Jeremy D and Sans, Miquel and Satsangi, Jack and Schreiber, Stefan and Simms, Lisa A and Sventoraityte, Jurgita and Targan, Stephan R and Taylor, Kent D and Tremelling, Mark and Verspaget, Hein W and de Vos, Martine and Wijmenga, Cisca and Wilson, David C and Winkelmann, Juliane and Xavier, Ramnik J and Zeissig, Sebastian and Zhang, Bin and Zhang, Clarence K and Zhao, Hongyu and Silverberg, Mark S and Annese, Vito and Hakonarson, Hakon and Brant, Steven R and Radford-Smith, Graham and Mathew, Christopher G and Rioux, John D and Schadt, Eric E and ... and Int IBD Genetics Consortium IIBDGC and International IBD Genetics Consortium (IIBDGC) and The International IBD Genetics Consortium (IIBDGC) and Region Örebro län and Örebro universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 2012, Volume 491, Issue 7422, pp. 119 - 124
Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with... 
HYPER-IGE SYNDROME | RISK LOCI | NETWORK | NUMBER | METAANALYSIS | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | MUTATIONS | EXPRESSION | Crohn Disease - genetics | Humans | Inflammatory Bowel Diseases - immunology | Colitis, Ulcerative - genetics | Mycobacterium tuberculosis - immunology | Inflammatory Bowel Diseases - physiopathology | Colitis, Ulcerative - immunology | Host-Pathogen Interactions - immunology | Mycobacterium tuberculosis - pathogenicity | Haplotypes - genetics | Mycobacterium - pathogenicity | Mycobacterium Infections - genetics | Inflammatory Bowel Diseases - genetics | Crohn Disease - microbiology | Mycobacterium Infections - microbiology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Reproducibility of Results | Mycobacterium - immunology | Crohn Disease - immunology | Genome, Human - genetics | Phenotype | Colitis, Ulcerative - microbiology | Host-Pathogen Interactions - genetics | Polymorphism, Single Nucleotide - genetics | Inflammatory Bowel Diseases - microbiology | Crohn Disease - physiopathology | Colitis, Ulcerative - physiopathology | Inflammatory bowel disease | Candidates | Tuberculosis | Architecture | Genetics | Genomes | Diabetes | Gene expression | Health risk assessment | Immune system | Index Medicus | Rheumatology and Autoimmunity | Basic Medicine | Medical Genetics | Medicinsk genetik | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
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3. Full Text Validated High Resolution Mass Spectrometry-Based Approach for Metabolomic Fingerprinting of the Human Gut Phenotype
by Vanden Bussche, Julie and Marzorati, Massimo and Laukens, Debby and Vanhaecke, Lynn
Analytical Chemistry, ISSN 0003-2700, 10/2015, Volume 87, Issue 21, pp. 10927 - 10934
Fecal samples are an obvious choice for metabolomic approaches, since they can be obtained non-invasively and allow one to study the interactions between the... 
CHEMISTRY, ANALYTICAL | METABONOMICS | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | PERFORMANCE | ULCERATIVE-COLITIS | FERMENTATION | MICROBIOTA | HEALTH | MODEL | FECAL METABOLOMICS | Metabolomics | Chromatography, High Pressure Liquid - methods | Intestines - microbiology | Humans | Intestines - metabolism | Feces | Mass Spectrometry - methods | Usage | Analysis | Gastrointestinal diseases | Research | Diagnosis | Biological markers | Mass spectrometry | Analytical chemistry | Genotype & phenotype | DNA fingerprints | Metabolites | Biomarkers | Chromatography | Index Medicus | Human | Fingerprinting | Computer simulation | Mathematical models | In vitro testing
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4. Full Text Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
by Franke, Ane and McGovern, Dermot P. B and Barrett, Jeffrey C and Wang, Kai and Radford-Smith, Graham L and Ahmad, Tariq and Lees, Charlie W and Balschun, Tobias and Lee, James and Roberts, Rebecca and Anderson, Carl A and Bis, Joshua C and Bumpstead, Suzanne and Ellinghaus, David and Festen, Eleonora M and Georges, Michel and Green, Todd and Haritunians, Talin and Jostins, Luke and Latiano, Anna and Mathew, Christopher G and Montgomery, Grant W and Prescott, Natalie J and Raychaudhuri, Soumya and Rotter, Jerome I and Schumm, Philip and Sharma, Yashoda and Simms, Lisa A and Taylor, Kent D and Whiteman, David and Wijmenga, Cisca and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Cohen, Albert and Colombel, Jean-Frederick and Cottone, Mario and Stronati, Laura and Denson, Ted and de Vos, Martine and D'Inca, Renata and Dubinsky, Marla and Edwards, Cathryn and Florin, Tim and Franchimont, Denis and Gearry, Richard and Glas, Jürgen and van Gossum, Ane and Guthery, Stephen L and Halfvarson, Jonas and Verspaget, Hein W and Hugot, Jean-Pierre and Karban, Amir and Laukens, Debby and Lawrance, Ian and Lemann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and Mowat, Craig and Newman, William and Panés, Julián and Phillips, Anne and Proctor, Deborah D and Regueiro, Miguel and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Seibold, Frank and Steinhart, A. Hillary and Stokkers, Pieter C. F and Torkvist, Leif and Kullak-Ublick, Gerd and Wilson, David and Walters, Thomas and Targan, Stephan R and Brant, Steven R and Rioux, John D and D'Amato, Mauro and Weersma, Rinse K and Kugathasan, Subra and Griffiths, Anne M and Mansfield, John C and Vermeire, Severine and Duerr, Richard H and Silverberg, Mark S and Satsangi, Jack and Schreiber, Stefan and Cho, Judy H and Annese, Vito and Hakonarson, Hakon and Daly, Mark J and Parkes, Miles and Hälsoakademin and Örebro universitet
Nature genetics, ISSN 1061-4036, 2010, Volume 42, Issue 12, pp. 1118 - 1125
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls... 
COMMON VARIANTS | ACTIVATION | INFLAMMATORY-BOWEL-DISEASE | PROTEIN | NEDD4 FAMILY | GENE | GENETICS & HEREDITY | SEQUENCE VARIANTS | RECEPTOR | IDENTIFICATION | ASSOCIATION | Genetic Variation | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Humans | Computational Biology | Genetic Loci - genetics | Crohn Disease - etiology | Genome, Human - genetics | Genetic Linkage | Care and treatment | Methyltransferases | Physiological aspects | Disease susceptibility | Genetic aspects | Crohn's disease | Research | Risk factors | Inflammatory bowel disease | Genetics | Genomics | Meta-analysis | Index Medicus | Medicine | Medicin | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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5. Full Text Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
by Anderson, Carl A and Boucher, Gabrielle and Lees, Charlie W and Franke, Ane and D'Amato, Mauro and Taylor, Kent D and Lee, James C and Goyette, Philippe and Imielinski, Marcin and Latiano, Anna and Lagacé, Caroline and Scott, Regan and Amininejad, Leila and Bumpstead, Suzannah and Baidoo, Leonard and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Colombel, Jean-Frédéric and Denson, Lee A and de Vos, Martine and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Fehrmann, Rudolf S. N and Floyd, James A. B and Florin, Timothy and Franchimont, Denis and Franke, Lude and Georges, Michel and Glas, Jürgen and Glazer, Nicole L and Guthery, Stephen L and Haritunians, Talin and Hayward, Nicholas K and Hugot, Jean-Pierre and Jobin, Gilles and Laukens, Debby and Lawrance, Ian and Lémann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and McGovern, Dermot P and Milla, Monica and Montgomery, Grant W and Morley, Katherine I and Mowat, Craig and Ng, Aylwin and Newman, William and Ophoff, Roel A and Papi, Laura and Palmieri, Orazio and Peyrin-Biroulet, Laurent and Panés, Julián and Phillips, Anne and Prescott, Natalie J and Proctor, Deborah D and Roberts, Rebecca and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Schumm, Philip and Seibold, Frank and Sharma, Yashoda and Simms, Lisa A and Seielstad, Mark and Steinhart, A. Hillary and Targan, Stephan R and van den Berg, Leonard H and Vatn, Morten and Verspaget, Hein and Walters, Thomas and Wijmenga, Cisca and Wilson, David C and Westra, Harm-Jan and Xavier, Ramnik J and Zhao, Zhen Z and Ponsioen, Cyriel Y and Andersen, Vibeke and Torkvist, Leif and Gazouli, Maria and Anagnou, Nicholas P and Karlsen, Tom H and Kupcinskas, Limas and Sventoraityte, Jurgita and Mansfield, John C and Kugathasan, Subra and Silverberg, Mark S and Halfvarson, Jonas and Rotter, Jerome I and Mathew, Christopher G and Griffiths, Anne M and Gearry, Richard and Ahmad, Tariq and Brant, Steven R and Chamaillard, Mathias and ... and Hälsoakademin and Örebro universitet
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 3, pp. 246 - 252
Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six... 
COMMON VARIANTS | CELLS | INFLAMMATORY-BOWEL-DISEASE | PROTEIN | CROHNS-DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | GENE-EXPRESSION | ENRICHMENT | MULTIPLE | GENOME-WIDE ASSOCIATION | Crohn Disease - genetics | Risk | Genome-Wide Association Study | Humans | Colitis, Ulcerative - genetics | Genetic aspects | Disease susceptibility | Research | Risk factors | Ulcerative colitis | Meta-analysis | Studies | Inflammatory bowel disease | Celiac disease | Genetics | Genomics | Genes | Index Medicus | Medicine | Medicin | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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6. Full Text Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
by Fisher, Sheila A and Regueiro, Miguel D and Anderson, Carl A and Prescott, Natalie J and Mathew, Christopher G and Rutgeerts, Paul and Parkes, Miles and Steinhart, A Hillary and Drummond, Hazel and Bitton, Alain and Georges, Michel and Gut, Ivo and Jewell, Derek and Barrett, Jeffrey C and Daly, Mark J and Dewit, Olivier and Bumpstead, Suzannah and Hansoul, Sarah and Hugot, Jean-Pierre and Barmada, M Michael and Xavier, Ramnik J and Libioulle, Cécile and Tremelling, Mark and Laukens, Debby and Datta, Lisa Wu and Kistner, Emily O and Onnie, Clive M and Griffiths, Anne M and Franchimont, Denis and Lathrop, Mark and Nimmo, Elaine and Green, Todd and Mansfield, John and Zelenika, Diana and Deloukas, Panos and Taylor, Kent D and Ahmad, Tariq and de Vos, Martine and Van Gossum, André and Duerr, Richard H and Silverberg, Mark S and Nicolae, Dan L and Rotter, Jerome I and Schumm, L Philip and Cardon, Lon R and Ghori, Jilur and Heath, Simon and Dassopoulos, Themistocles and Vermeire, Severine and Sandor, Cynthia and Satsangi, Jack and Marchini, Jonathan and Gwilliam, Rhian and Louis, Edouard and Rioux, John D and Mni, Myriam and Belaiche, Jacques and Targan, Stephan R and Brant, Steven R and Murtha, Michael T and Cho, Judy H and Wellcome Trust Case Control and NIDDK IBD Genetics Consortium and Belgian-French IBD Consortium and Wellcome Trust Case Control Consortium and the NIDDK IBD Genetics Consortium and the Belgian-French IBD Consortium and the Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 08/2008, Volume 40, Issue 8, pp. 955 - 962
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data... 
GENETIC-VARIATION | CELLS | VARIANTS | COLITIS | GENETICS & HEREDITY | RISK | LARGE-SCALE | NONSYNONYMOUS SNPS | IL-23 | EXPRESSION | MULTIPLE | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome, Human | Quantitative Trait Loci | Humans | Physiological aspects | Crohn's disease | Genetic aspects | Research | Genetic susceptibility | Risk factors | Inflammatory bowel disease | Studies | Medical research | Genetics | Genomics | Crohns disease | Index Medicus
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7. Full Text Assessment of faecal microbial transfer in irritable bowel syndrome with severe bloating
by Holvoet, Tom and Joossens, Marie and Wang, Jun and Boelens, Jerina and Verhasselt, Bruno and Laukens, Debby and van Vlierberghe, Hans and Hindryckx, Pieter and De Vos, Martine and De Looze, Danny and Raes, Jeroen
Gut, ISSN 0017-5749, 05/2017, Volume 66, Issue 5, pp. 980 - 982
Of note, however, placebo response rates in similar IBS patient cohorts are reported to be approximately 37.5%, which is considerably lower than the response... 
RICHNESS | GASTROENTEROLOGY & HEPATOLOGY | Abdominal Pain | Flatulence | Feces | Irritable Bowel Syndrome | Constipation | Humans | Inflammatory bowel diseases | Clinical trials | Transplantation | Patients | Manuscripts | Abdomen | Microbiota |