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1. Full Text The Human Phenotype Ontology in 2017
by Kohler, S and Vasilevsky, N.A and Engelstad, M and Foster, E and McMurry, J and Ayme, S and Baynam, G and Bello, S.M and Boerkoel, C.F and Boycott, K.M and Brudno, M and Buske, O.J and Chinnery, P.F and Cipriani, V and Connell, L.E and Dawkins, H.J and DeMare, L.E and Devereau, A.D and Vries, B.B. de and Firth, H.V and Freson, K and Greene, D and Hamosh, A and Helbig, I and Hum, C and Jahn, J.A and James, R and Krause, R and Laulederkind, S.J.F and Lochmuller, H and Lyon, G.J and Ogishima, S and Olry, A and Ouwehand, W.H and Pontikos, N and Rath, A and Schaefer, F and Scott, R.H and Segal, M and Sergouniotis, P.I and Sever, R and Smith, C.L and Straub, V and Thompson, R and Turner, C and Turro, E and Veltman, M.W and Vulliamy, T and Yu, J and Ziegenweidt, J. von and Zankl, A and Zuchner, S and Zemojtel, T and Jacobsen, J.O and Groza, T and Smedley, D and Mungall, C.J and Haendel, M and Robinson, P.N and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Nucleic Acids Research, ISSN 0305-1048, 2017, Volume 45, Issue 1, pp. D865 - d876
Deep phenotyping has been defined as the precise and comprehensive analysis of phenotypic abnormalities in which the individual components of the phenotype are... 
DISEASE-GENE-DISCOVERY | RARE-DISEASE | VARIANT PRIORITIZATION | MATCHMAKER EXCHANGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLATELET DISORDERS | CANDIDATE GENES | MODEL ORGANISM | EPILEPTIC ENCEPHALOPATHY | GENOME-WIDE ASSOCIATION | DEVELOPMENTAL DISORDERS | Computational Biology - methods | Phenotype | Algorithms | Biological Ontologies | Humans | Rare Diseases - diagnosis | Genetic Association Studies - methods | Software | Genomics - methods | Rare Diseases - etiology | Translational Medical Research - methods | Precision Medicine - methods | BASIC BIOLOGICAL SCIENCES | Database Issue
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2. Full Text The Gene Ontology Resource: 20 years and still GOing strong
by Carbon, S and Douglass, E and Dunn, N and Good, B and Harris, N.L and Lewis, S.E and Mungall, C.J and Basu, S and Chisholm, R.L and Dodson, R.J and Hartline, E and Fey, P and Thomas, P.D and Albou, L.P and Ebert, D and Kesling, M.J and Mi, H and Muruganujan, A and Huang, X and Poudel, S and Mushayahama, T and Hu, J.C and LaBonte, S.A and Siegele, D.A and Antonazzo, G and Attrill, H and Brown, N.H and Fexova, S and Garapati, P and Jones, T.E.M and Marygold, S.J and Millburn, G.H and Rey, A.J and Trovisco, V and Dos Santos, G and Emmert, D.B and Falls, K and Zhou, P and Goodman, J.L and Strelets, V.B and Thurmond, J and Courtot, M and Osumi, D.-S and Parkinson, H and Roncaglia, P and Acencio, M.L and Kuiper, M and Lreid, A and Logie, C and Lovering, R.C and Huntley, R.P and Denny, P and Campbell, N.H and Kramarz, B and Acquaah, V and Ahmad, S.H and Chen, H and Rawson, J.H and Chibucos, M.C and Giglio, M and Nadendla, S and Tauber, R and Duesbury, M.J and Del, N.-T and Meldal, B.H.M and Perfetto, L and Porras, P and Orchard, S and Shrivastava, A and Xie, Z and Chang, H.Y and Finn, R.D and Mitchell, A.L and Rawlings, N.D and Richardson, L and Sangrador-Vegas, A and Blake, J.A and Christie, K.R and Dolan, M.E and Drabkin, H.J and Hill, D.P and Ni, L and Sitnikov, D and Harris, M.A and Oliver, S.G and Rutherford, K and Wood, V and Hayles, J and Bahler, J and Lock, A and Bolton, E.R and De Pons, J and Dwinell, M and Hayman, G.T and Laulederkind, S.J.F and Shimoyama, M and Tutaj, M and Wang, S.-J and D'Eustachio, P and Matthews, L and ... and Gene Ontology Consortium and The Gene Ontology Consortium
Nucleic Acids Research, ISSN 0305-1048, 01/2019, Volume 47, Issue D1, pp. D330 - D338
Abstract The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products.... 
DATABASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Database Issue
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3. Full Text Congenital Lack of COX-2 Affects Mechanical and Geometric Properties of Bone in Mice
by Chen, Q and Rho, J. Y and Fan, Z and Laulederkind, S. J. F and Raghow, R
Calcified Tissue International, ISSN 0171-967X, 10/2003, Volume 73, Issue 4, pp. 387 - 392
We compared the mechanical properties of bones from mice lacking either a functional cycloxygenase-1 (C57BL6/DBA COX-1−/−; n = 9) or COX-2 (C57BL6/DBA... 
PGE 2 | Mechanical properties | Cyclooxygenase | Philosophy | Knockout | Nanoindentation | PGE | knockout | CELLS | RATS | cyclooxygenase | nanoindentation | STRENGTH | INDUCTION | CYCLOOXYGENASE-1 | mechanical properties | ENDOCRINOLOGY & METABOLISM | ELASTIC-MODULUS | GENE DISRUPTION | EXPRESSION | PROSTAGLANDIN E-2 | Prostaglandin-Endoperoxide Synthases - genetics | Femur - pathology | Bone Diseases - genetics | Isoenzymes - genetics | Cyclooxygenase 2 | Mice, Inbred C57BL | Cyclooxygenase 1 | Bone Matrix - physiopathology | Genotype | Male | Materials Testing | Femur - physiopathology | Bone Matrix - pathology | Mice, Knockout | Membrane Proteins | Biomechanical Phenomena | Animals | DNA - analysis | Polymerase Chain Reaction | Bone Diseases - congenital | Mice, Inbred DBA | Mice | Nanotechnology | Bone Diseases - enzymology
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4. Full Text The Regulation of PGE2 Biosynthesis in MG-63 Osteosarcoma Cells by IL-1 and FGF Is Cell Density-Dependent
by Laulederkind, Stanley J.F and Kirtikara, Kanyawim and Raghow, Rajendra and Ballou, Leslie R
Experimental Cell Research, ISSN 0014-4827, 08/2000, Volume 258, Issue 2, pp. 409 - 416
We investigated the molecular mechanisms by which treatment of the human osteoblast-like cell line MG-63 with interleukin 1 (IL-1) and/or fibroblast growth... 
interleukin 1β | cell density | prostaglandin E2 | fibroblast growth factor 1 | cytosolic phospholipase A2 | osteoblast | prostaglandin H synthase | osteosarcoma | interleukin 1 | Osteosarcoma | Osteoblast | Interleukin 1β | Prostaglandin E | Cell density | Cytosolic phospholipase A | Fibro-blast growth factor 1 | Prostaglandin H synthase
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5. Full Text PhenoMiner: A quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease
by Wang, Shur-Jen and Laulederkind, Stanley J.F and Hayman, G. Thomas and Petri, Victoria and Liu, Weisong and Smith, Jennifer R and Nigam, Rajni and Dwinell, Melinda R and Shimoyama, Mary
Database, ISSN 1758-0463, 2015, Volume 2015
Rats have been used extensively as animal models to study physiological and pathological processes involved in human diseases. Numerous rat strains have been... 
ONTOLOGIES | SUBSTITUTION | GENETIC-BASIS | BLOOD-PRESSURE QTL | MODELS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | INJURY | Angiotensin Amide - metabolism | Animals | Biological Ontologies | Humans | Angiotensin Amide - genetics | Databases, Genetic | Rats | Software | Data Mining - methods | Kidney Diseases - genetics | Kidney Diseases - metabolism
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6. Full Text PhenoMiner: Quantitative phenotype curation at the rat genome database
by Laulederkind, Stanley J. F and Liu, Weisong and Smith, Jennifer R and Hayman, G. Thomas and Wang, Shur-Jen and Nigam, Rajni and Petri, Victoria and Lowry, Timothy F and De Pons, Jeff and Dwinell, Melinda R and Shimoyama, Mary
Database, ISSN 1758-0463, 2013, Volume 2013, p. bat015
The Rat Genome Database (RGD) is the premier repository of rat genomic and genetic data and currently houses >40 000 rat gene records as well as human and... 
ONTOLOGY | PHYSIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | TOOL | Phenotype | Animals | Humans | Molecular Sequence Annotation | Genome - genetics | Databases, Genetic | Rats | Workflow | Mice | Software | Data Mining - methods
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7. Full Text Analysis of disease-associated objects at the Rat Genome Database
by Wang, Shur-Jen and Laulederkind, Stanley J. F and Hayman, G.T and Smith, Jennifer R and Petri, Victoria and Lowry, Timothy F and Nigam, Rajni and Dwinell, Melinda R and Worthey, Elizabeth A and Munzenmaier, Diane H and Shimoyama, Mary and Jacob, Howard J
Database, ISSN 1758-0463, 2013, Volume 2013, p. bat046
The Rat Genome Database (RGD) is the premier resource for genetic, genomic and phenotype data for the laboratory rat, Rattus norvegicus. In addition to... 
ONTOLOGY | TARGETS | GENES | MATHEMATICAL & COMPUTATIONAL BIOLOGY | TOOL | Genetic Predisposition to Disease | Disease - genetics | Genetic Association Studies | Chromosomes, Mammalian - genetics | Humans | Molecular Sequence Annotation | Genome - genetics | Databases, Genetic | Rats | Nervous System Diseases - genetics | Cardiovascular Diseases - genetics | Obesity - genetics | Animals | Mice | Software | Quantitative Trait Loci - genetics
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